Clinical trials: sponsored by Case Comprehensive Cancer Center
Head and Neck Cancer
Temporally Feathered Radiation Therapy (TFRT) for Head and Neck Squamous Cell Carcinoma
This study will evaluate the feasibility of using more advanced IMRT (intensity modulated radiation therapy) techniques. This new technique is termed Temporally Feathered Radiation Therapy (TFRT).
- Trial name
- NCT03768856
- Testing
- Temporally Feathered Radiation Therapy (TFRT)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Case Comprehensive Cancer Center
Breast Cancer
Efficacy of Digital Breast Tomosynthesis + Standard 2- Dimensional Mammography in Breast Cancer
The purpose of this study is to determine if a 3-dimensional mammogram (DBT) may provide additional information to evaluate the extent of disease and additional findings that would aid in staging a new breast cancer patient.
- Trial name
- NCT03190083
- Testing
- 2-dimensional mammogram, digital breast tomosynthesis (DBT)
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Case Comprehensive Cancer Center
Actinic Keratosis
Vitamin D Supplementation as a Neoadjuvant for Photodynamic Therapy of Actinic Keratoses
This study is open to individuals with Actinic Keratoses (skin lesions that have the potential to turn into skin cancer), who are receiving photodynamic therapy (PDT) as part of their clinical care.
- Trial name
- NCT04140292
- Testing
- Photodynamic therapy (PDT), Vitamin D3
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Case Comprehensive Cancer Center
Hepatic Malignancies
Comparison of Yttrium-90 Absorbed Doses Using PET/CT Versus PET/MR Imaging for Hepatic Malignancies
The purpose of this study is to compare the results of positron emission tomography/computer tomography (PET/CT) to positron emission tomography/magnetic resonance imaging (PET/MRI) to help determine any added advantage of one…
- Trial name
- NCT04332419
- Testing
- PET/CT, PET/MR, SIRT with Y-90
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Case Comprehensive Cancer Center
Prostate Cancer
Apalutamide and Leuprolide in Intermediate and High-risk Prostate Cancer
This is a research study to test an investigational drug (Not FDA approved), Apalutamide given in combination with Leuprolide acetate (FDA approved) in men diagnosed with high-risk prostate cancer who have already selected to…
- Trial name
- NCT02770391
- Testing
- Leuprolide acetate, Apalutamide, Radical prostatectomy
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Case Comprehensive Cancer Center
Esophageal Cancer
Endoesophageal Brachytherapy for Patients With Esophageal Cancer
Depending upon the cancer stage, esophageal cancer can be treated with surgery, chemotherapy, radiation therapy, or a combination of these modalities.
- Trial name
- NCT03335813
- Testing
- Endoesophageal Brachytherapy
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Case Comprehensive Cancer Center
Prostate Cancer
Virtual Prostate Biopsy Protocol for Patients on Active Surveillance and at Risk of Prostate Cancer
The purpose of this study is to examine the use of MRI surveillance for patients with no prostate cancer, potential prostate cancer, or diagnosed low-grade prostate cancer.
- Trial name
- NCT03823001
- Testing
- virtual biopsy (VB) monitoring protocol
- Where
- United States
- Sponsor
- Case Comprehensive Cancer Center
Breast Cancer, Malignant Neoplasm of Breast
Breast Reconstruction Following Breast Cancer in Very High Risk Patients
The purpose of this study is to: 1. Evaluate whether immediate or delayed reconstruction should be offered for breast reconstruction candidates with higher risk for surgical complications by comparing complications, quality of…
- Trial name
- NCT03261323
- Testing
- Immediate Breast Reconstruction, Delayed Breast Reconstruction, Breast-Q questionnaire
- Where
- United States
- Sponsor
- Case Comprehensive Cancer Center
Non-muscle Invasive Bladder Cancer (NMIBC), Bladder Tumor (TURBT)
Continuous Bladder Irrigation Following Transurethral Resection of Bladder Tumors
The purpose of this pilot study is to determine if washing out the bladder with large volumes of saline after surgical removal of bladder tumors helps to decrease the number of loose cells floating within the bladder after…
- Trial name
- NCT03839472
- Testing
- CBI
- Where
- United States
- Sponsor
- Case Comprehensive Cancer Center
Malignant Neoplasm of Prostate
Fluciclovine (Axumin) PET/CT vs. NaF PET/CT in Prostate Cancer Osseous Metastatic Disease
The purpose of this study is to look at whether F-18 Fluciclovine (i.e. Axumin) is better or as good as F-18 Sodium Fluoride (F-18 NaF) when looking at bone disease from prostate cancer.
- Trial name
- NCT04765423
- Testing
- [F-18] NaF PET/CT, [F-18] fluciclovine PET/CT
- Where
- United States
- Sponsor
- Case Comprehensive Cancer Center
Vaginal Surgery, Laparoscopic Surgery
Improved Intra-operative Safety From Optimal Selection of Anti-slip Surface
To identify the best surface to minimize the risk of intra-operative slipping when placed in Trendelenburg position. The outcomes of interest are to minimize the amount of movement from predefined anatomic landmarks and maximize…
- Trial name
- NCT03573557
- Testing
- Pink Pad, Bean Bag, Gel Pad
- Where
- United States
- Volunteers
- 159 people
- Sponsor
- Case Comprehensive Cancer Center
Breast Cancer, Physical Activity
Physical Activity Intervention to Reduce Functional Health Disparities Among Breast Cancer Survivors
The purpose of this research study is to determine whether a physical activity (exercise) program in the community will improve the functional and overall health status of older women with a history of breast cancer.
- Trial name
- NCT02763228
- Testing
- Aerobic Training - Fixed Schedule, Resistance Training - Fixed Schedule, Walking program
- Where
- 3 sites in United States
- Volunteers
- 218 people
- Sponsor
- Case Comprehensive Cancer Center
Postoperative Ileus, Gastrointestinal Cancer
Acupuncture for the Treatment of Postoperative Ileus After Gastrointestinal Surgery
The goal of this study is to learn if electro-acupuncture is a feasible treatment option for postoperative ileus after abdominal surgery.
- Trial name
- NCT04713241
- Testing
- Electro-acupuncture, Standard of Care Bowel rest
- Sponsor
- Case Comprehensive Cancer Center
Malignant Neoplasm of Ovary, Malignant Neoplasm of Fallopian Tube
Debulking Surgery in Ovarian Cancer
The purpose of this study is to see if patients undergoing a laparoscopic surgery for removal of ovarian, fallopian tube, or primary peritoneal cancer following neoadjuvant chemotherapy (neoadjuvant- chemotherapy given before…
- Conditions
- Malignant Neoplasm of Ovary, Malignant Neoplasm of Fallopian Tube, Malignant Neoplasm of Peritoneum
- Trial name
- MIID-SOC (NCT03378128)
- Testing
- Diagnostic laparoscopy
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Case Comprehensive Cancer Center
Advanced Cancer
Online Information and Support for Distance Caregivers
This study seeks to test the effectiveness of two arms of an intervention that use videoconference technology for distance caregivers of patients with advanced cancer.
- Trial name
- NCT02666183
- Testing
- Video-C, Nurse Coaching, Web-Only
- Where
- United States
- Volunteers
- 397 people, healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center
Peripheral Neuropathy
Clinical Trial of Acupuncture for Chemotherapy-Induced Peripheral Neuropathy
The goal of this clinical research study is to learn if one acupuncture treatment approach is more effective than another in helping to relieve chemo-therapy induced neuropathy in cancer patients.
- Trial name
- NCT03881748
- Testing
- Manual acupuncture, Electro-acupuncture
- Where
- United States
- Sponsor
- Case Comprehensive Cancer Center
Hematologic Diseases
Lavender Oil Aromatherapy for The Treatment of Acute Anxiety During Bone Marrow Biopsy Procedures
The purpose of this study is to assess the effectiveness of lavender oil as compared to standard of care (SOC) to relieve anxiety in participants undergoing a bone marrow aspirate and biopsy procedure
- Trial name
- NCT05102331
- Testing
- Lavender Oil Aromatherapy, BMAB procedure
- Sponsor
- Case Comprehensive Cancer Center
Positron Emission Tomography-Magnetic Resonance (PET-MR)
Enhancing SUV Accuracy of PET/MR for Clinical Trial Qualification
Standardized Uptake Values (SUVs), normalized activity concentration, measured using PET/MR have inaccuracies ≥ 20% which exceeds National Cancer Institute / American College of Radiology Imaging Network (NCI/ACRIN), Radiological…
- Trial name
- NCT03603925
- Testing
- Positron Emission Test / Magnetic Resonance (PET/MR), Positron Emission Test / Computed Tomography (PET/CT)
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Case Comprehensive Cancer Center
Smoking Cessation
Innovations to Prevent Relapse Among Low-income African American Smokers
The purpose of this research is to study a relapse prevention program for adult former smokers in Northeast Ohio. The study will also look at how different people respond to the program.
- Trial name
- NCT03982576
- Testing
- Nicotine replacement therapy (NRT), CS-CBT intervention, Path2Quit
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Case Comprehensive Cancer Center
Dehydration, Head & Neck Cancer
DRIHNC - Dehydration Reduction in Head & Neck Cancer
The purpose of this study is to decrease the rate of visits to the Emergency Department (ED) and Acute Care Clinics (ACC) for dehydration for head \& neck (H\&N) and esophageal cancer patients that are given Gatorade while…
- Conditions
- Dehydration, Head & Neck Cancer, Esophageal Cancer
- Trial name
- NCT03799380
- Testing
- Gatorade G2, Standard of care nutritional support
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Case Comprehensive Cancer Center