Clinical trials: sponsored by Cedars-Sinai Medical Center
Chronic Pain
Pragmatic Comparative Effectiveness Trial of Evidence-based, On-demand, Digital Behavioral Treatments for Chronic Pain
This study compared two available, evidence-based, at-home digital pain treatment programs. The goal is to see if one approach is better than the other, and whether certain patients respond to one more than the other.
- Trial name
- NCT04933474
- Testing
- painTRAINER®, Skills-Based VR
- Where
- United States
- Volunteers
- 330 people
- Sponsor
- Cedars-Sinai Medical Center
Pituitary Tumor
Pituitary Tumor Surveillance: Pathogenic Correlation
The purpose of this study is to observe predictors of pituitary tumor recurrence and markers of persistent disease activity in patients harboring pituitary mass lesions of all types.
- Trial name
- NCT00599092
- Where
- United States
- Volunteers
- 1,250 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Wounds and Injuries
Food is Medicine Prospective Study
The purpose of this study is to examine the impact of a medically tailored post-operative meal delivery program on surgical outcomes and metabolic lab markers in orthopaedic trauma patients.
- Trial name
- FIM (NCT07169448)
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Cedars-Sinai Medical Center
Coronary Artery Disease, Non-Obstructive Coronary Atherosclerosis
WARRIOR Ancillary Study for CCTA Analysis
In this study, quantitative characterization of plaque using coronary computed tomographic angiography (CTA) will be used to determine if women who were treated with intensive medical therapy have a greater reduction in the…
- Conditions
- Coronary Artery Disease, Non-Obstructive Coronary Atherosclerosis, Ischemia
- Trial name
- NCT05035056
- Where
- United States
- Volunteers
- 191 people
- Sponsor
- Cedars-Sinai Medical Center
Diabetes Mellitus
This Study is to Evaluate Whether Receiving Education and Glucose Monitoring With the CGM Device Will Improve Patient-reported Outcomes by Improving Patient's Satisfaction and Quality of Life (QOL) With Glucose Monitoring Device
The purpose of the study is to improve patient-reported outcomes by improving patient's satisfaction and quality of life (QOL) with glucose monitoring device through pre and post satisfaction survey of patient with diabetes.
- Trial name
- CGM QOL (NCT06965803)
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Cedars-Sinai Medical Center
Obesity, Healthy Lifestyle
Single Nuclei RNA-seq to Map Adipose Cellular Populations and Senescent Cells in Older Subjects
All participants will undergo baseline biopsies of subcutaneous abdominal adipose tissue for cellular/molecular profiling via snRNA-seq and metabolic/physiological assessments (insulin sensitivity, glucose tolerance, and β-cell…
- Trial name
- NCT05653258
- Testing
- Lifestyle Intervention, Dasatinib 100 MG, Quercetin 1000mg
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Heart Transplantation
Precise Cooler for Donor Heart Transport
The investigators are doing this study to compare approaches to cold storage of donor hearts during transportation. The adjustable temperature RYOBI cooler should allow precise temperature control while reducing environmental…
- Trial name
- NCT07354763
- Testing
- Organ transport using SherpaPak, Ryobi cooler for Organ Transport
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Cedars-Sinai Medical Center
ICU Delirium
Virtual Reality for ICU Delirium Prevention
The purpose of this study is to evaluate whether daily exposure to immersive virtual reality (VR) can reduce the incidence of delirium in high-risk, non-intubated ICU patients.
- Trial name
- NCT07357389
- Testing
- Virtual Reality therapeutics
- Where
- United States
- Volunteers
- 822 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Chronic Maxillary Rhinosinusitis
Using Navigation to Improve Accuracy of Maxillary Balloon Sinusotomy
The purpose of the research is to examine the effectiveness of navigation in maxillary sinus balloon dilation for the treatment of chronic maxillary rhinosinusitis.
- Trial name
- NCT06567821
- Testing
- RELIEVA SPINPLUS® NAV Balloon Sinusplasty System
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Prostate Cancer
Intensive Cholesterol-Lowering and CD8+ T Cells in Prostate Cancer
To test the hypothesis that intensive cholesterol lowering (iCL) therapy has anti-tumor immune modulating activity, the investigators will conduct an open-label, single-arm phase II trial in prostate cancer patients who are in…
- Trial name
- NCT06437574
- Testing
- Vytorin, Ezetimibe
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Cedars-Sinai Medical Center
Eustachian Tube Dysfunction
Effect of Novel Exhalational Delivery System With Fluticasone (EDS-FLU) on Eustachian Tube Dysfunction (ETD)
Intranasal nasal steroid sprays are the mainstay of treatment for chronic Eustachian tube dysfunction despite having little supportive evidence in the literature.
- Trial name
- NCT05275686
- Testing
- Fluticasone Propionate 93 MCG/1 ACTUATION Nasal Spray
- Where
- 4 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Symptomatic Parkinson Disease, REM Sleep Behavior Disorder
Terazosin and Parkinson's Disease Extension Study
The purpose of this study is to investigate the long-term effects of treatment with the selective post-synaptic a1-adrenergic blocker terazosin on serial in a population of subjects with defined pre-motor Parkinson's disease (PD)…
- Conditions
- Symptomatic Parkinson Disease, REM Sleep Behavior Disorder, Pre-motor Parkinson's Disease
- Trial name
- NCT05109364
- Testing
- Terazosin therapy
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Cedars-Sinai Medical Center
REM Sleep Behavior Disorder, Pre-motor Parkinson's Disease
Terazosin Effect on Cardiac Changes in Early Parkinson's Disease
Parkinson's disease (PD) is characterized by many non-motor symptoms that occur several years before the diagnosis, in particular idiopathic REM behavior disorder (iRBD), which is associated with autonomic impairment.
- Conditions
- REM Sleep Behavior Disorder, Pre-motor Parkinson's Disease, Symptomatic Parkinson Disease
- Trial name
- NCT04386317
- Testing
- Terazosin
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Cedars-Sinai Medical Center
REM Sleep Behavior Disorder, Pre-motor Parkinson Disease
Cardiac Changes in Early Parkinson's Disease: A Follow up Study
The purpose of this study is to investigate the long-term effects of treatment with the adrenergic blocker carvedilol on serial DaTscan, a dopamine transporter (DAT) single photon emission computerized tomography (SPECT) imaging…
- Conditions
- REM Sleep Behavior Disorder, Pre-motor Parkinson Disease, Symptomatic Parkinson Disease
- Trial name
- NCT04218968
- Testing
- Carvedilol
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Cedars-Sinai Medical Center
Crohn Disease, CARD9 S12N Risk Allele
Pilot Study of Posaconazole in Crohn's Disease
This trial is designed to evaluate the effects of oral antifungal treatment with posaconazole on active Crohn's disease (CD) activity and the burden of Malassezia spp.
- Trial name
- NCT04966585
- Testing
- Posaconazole Delayed Release Oral Tablet
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Cedars-Sinai Medical Center
Idiopathic Pulmonary Fibrosis
Atezolizumab for Idiopathic Pulmonary Fibrosis
The purpose of this study is to determine the safety and preliminary efficacy of atezolizumab, an immune checkpoint inhibitor approved for the treatment of various cancers, in patients with idiopathic pulmonary fibrosis (IPF).
- Trial name
- NCT05515627
- Testing
- Atezolizumab
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Cedars-Sinai Medical Center
Cancer Pain, Visceral Pain
Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes
Patients with digestive tract malignancy often experience severe and unremitting abdominal pain that negatively affects physical, emotional, and social function, as well as health related quality of life (HRQOL).
- Conditions
- Cancer Pain, Visceral Pain, Gastrointestinal Neoplasms, Cancer of Gastrointestinal Tract
- Trial name
- NCT04907643
- Testing
- PICO G2 4k
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- Cedars-Sinai Medical Center
Crohn Disease
Stem Cell Transplantation in Crohn's Disease
Unfortunately, some patients with Crohn's disease (CD) fail to respond to the best clinical treatments and some only experience temporary benefit.
- Trial name
- NCT04224558
- Testing
- Mesna, Cyclophosphamide, Filgrastim
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Cedars-Sinai Medical Center
Financial Burden, Financial Toxicity
Proactive Costs of Care Study
The Proactive Costs of Care intervention is an educational intervention designed to help patients deal with the cost of cancer care.
- Conditions
- Financial Burden, Financial Toxicity, Financial Stress, Financial Navigation
- Trial name
- PCOC (NCT07217262)
- Testing
- Educational Intervention
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Bladder Cancer
A Novel Multiplex ELISA Assay for Evaluating Patients With Microscopic Hematuria for Bladder Cancer
To improve upon the non-invasive detection of BCa by further validating a multiplex ELISA assay directed at a BCa-associated diagnostic signature in voided urine samples of patients with microscopic hematuria.
- Trial name
- NCT03193541
- Where
- 8 sites in United States, Japan
- Volunteers
- 900 people
- Sponsor
- Cedars-Sinai Medical Center