Clinical trials: sponsored by Central Hospital, Nancy, France
Postoperative Pain
Continuous Pre-uterine Wound Infiltration Versus Intrathecal Morphine for Postoperative Analgesia After Cesarean Section
The cesarean section is considered as a painful surgery during the post operative period. Mothers may need to move immediately after the surgery to take care of their babies.
- Trial name
- NCT02279628
- Testing
- Ropivacaine, Morphine
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Central Hospital, Nancy, France
Knee Osteoarthritis
Spa Therapy in Knee Osteoarthritis (OA): Nancy-thermal
Non-pharmacological treatments are recommended for the management of knee osteoarthritis (EULAR or OARSI recommendations) and some thermal modalities may be effective for relieving symptoms in knee Osteoarthritis.
- Trial name
- Nancythermal (NCT01544647)
- Testing
- Usual spa protocol, Active spa protocol
- Where
- France
- Volunteers
- 283 people
- Sponsor
- Central Hospital, Nancy, France
Cardiovascular Diseases
Search of Biomarkers of Mineralocorticoid Receiver Activity : the Value of Neutrophil Gelatinase Associated Lipocalin (NGAL)in Serum or Urine in Human
Aldosterone and its target the mineralocorticoid receptor are implied in development of cardiovascular disease such as arterial high blood pressure or cardiac failure.
- Trial name
- NCT02129621
- Testing
- Urinary and blood lipococalin levels determination, Spironolactone
- Where
- 3 sites in France
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Heart Failure
Biomarkers and Therapeutic Modelisation in Heart Failure
The telemonitoring systems for congestive HF did not yet prove their efficacy despite initial encouraging results. Decongestion is one of the main objectives in Congestive HF, but an appropriate titration of diuretics is…
- Trial name
- BIOMIC (NCT01655134)
- Testing
- Blood simples, Capillary punction, Urine simples
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Central Hospital, Nancy, France
Post CVA Hypertension
Post CVA Persistent Hypertension Caring
The study HIPPOCRATE is a prospective open comparative study with a control group. The objective of this study is to show that an optimization of the caring of non controlled hypertended patients following a CVA (including a…
- Trial name
- Hippocrate (NCT01109251)
- Testing
- Auto-measure of the tension by an autotensiometer
- Where
- 2 sites in France
- Volunteers
- 240 people
- Sponsor
- Central Hospital, Nancy, France
Aging, Inflammation
Relationship Between Thoracic Aortic Structure Assessed B PET/CT Scan and Arterial Stiffness in Elderly Patients
The purpose of this study is to determine the relationship between thoracic aortic inflammation and arterial stiffness in elderly patients.
- Trial name
- FICTEP (NCT01963221)
- Testing
- fludeoxyglucose(18f), blood sample, cardiac and aortic magnetic resonance imaging
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Neuromuscular Blockade
Sugammadex-dosing in Bariatric Patients
Should the dose of sugammadex in morbid obese patients be calculated on the real body weight or the ideal body weight? The main objective of the trial is to compare in patients undergoing bariatric surgery the efficacy of…
- Trial name
- SugReBaCh-1 (NCT01570179)
- Testing
- ideal BW based sugammadex reversal of moderate block, real body weight based sugammadex reversal of moderate block, real body weight based sugammadex reversal of deep block
- Where
- 2 sites in France
- Volunteers
- 34 people
- Sponsor
- Central Hospital, Nancy, France
Vestibular Schwannoma
Vestibular Schwannoma and Psychological Factors
The surgery of a vestibular schwannoma induces balance disorders which have a an impact on the patient's daily life and disrupt their quality of life.
- Trial name
- NCT01743248
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Central Hospital, Nancy, France
Cardiovascular Pathology
NESCAV Nutrition Environment and Cardiovascular Health
Introduction. The cardiovascular diseases, at the origin of 4 deaths out of 10, remain the leading cause of mortality in Europe. According to WHO, this tendency will spread in 2020 on a worldwide scale.
- Trial name
- NESCAV (NCT01414179)
- Where
- France
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Osteoarthritis
Etude 3000 ARTHROSES Symptomatic Knee and Hip Osteoarthritis Prevalence Survey
Nationwide descriptive epidemiology survey aiming to determine lower limb OA prevalence, based on a validated method previously used to assess inflammatory rheumatism (rheumatoid arthritis and spondylarthropathy) prevalence in…
- Trial name
- 3000ARTHROSE (NCT01400529)
- Where
- 6 sites in France
- Volunteers
- 3,000 people
- Sponsor
- Central Hospital, Nancy, France
Ureteral Obstruction
Functional MR Urography
The objective of functional Uro MR is to add to an initial morphological phase, based on T2 and T1 weighted MR sequences, a sequential contrast-enhanced acquisition allowing to obtain functional semi-quantitative parameters from…
- Trial name
- NCT00301470
- Testing
- MR urography
- Where
- 16 sites in France
- Volunteers
- 550 people
- Sponsor
- Central Hospital, Nancy, France
Ischemic Stroke
Effect of Aspirin at the Acute Phase of Cerebral Ischemic Event.
Aspirin is the only anti-platelet medication used at the acute phase of ischemic stroke. The investigators would like to study laboratory effect of the first oral 300 mg dose of aspirin, given at hospital, after an ischemic…
- Trial name
- Aspirin (NCT01375400)
- Testing
- Aspirin, blood sample
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Central Hospital, Nancy, France
Severe Sepsis
Evaluation of MorphoTEP With the FDG Among Patients in Severe Sepsis of Unspecified Etiology
The objective of this pilot study is to estimate a procedure where the biological samples routinely obtained at the site of suspected infection could be guided by the early realization of a TEP with FDG coupled to scanner X, in…
- Trial name
- NCT00791310
- Testing
- Flucis
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Central Hospital, Nancy, France
Hospitalization
Adapted Physical Activity, Health-related Quality of Life and Satisfaction With Care in Hospitalized Children
The aim of this study is to assess the efficacy of adapted physical activity intervention on health-related quality of life and satisfaction with care in hospitalized children and adolescents.
- Trial name
- ACTIVHOP (NCT00828217)
- Testing
- adapted physical activity
- Where
- France
- Volunteers
- 312 people
- Sponsor
- Central Hospital, Nancy, France
Pneumonia
Probiotic Enteral Administration in Mechanically Ventilated Patients
The objective of this study is to assess the effects of a daily enteral supplementation with probiotics within a population of critically ill, mechanically ventilated patients.
- Trial name
- NCT00122408
- Testing
- Ergyphilus
- Where
- 3 sites in France
- Volunteers
- 740 people
- Sponsor
- Central Hospital, Nancy, France
Newly Diagnosed Breast Cancer, Surgery Programmed
Factors Correlated With Fatigue in Breast Cancer
The aim of this study is to identify the determinants of cancer-related fatigue, and the long-term effect of the different adjuvants treatments will be explored.
- Trial name
- FATSEIN (NCT01064427)
- Where
- 3 sites in France
- Volunteers
- 557 people
- Sponsor
- Central Hospital, Nancy, France
Newly Diagnosed, Multiple Myeloma
Comparison of Melphalan-Prednisone (MP) to MP Plus Thalidomide in the Treatment of Newly Diagnosed Very Elderly Patients (> 75 Years) With Multiple Myeloma
In multiple myeloma, combination chemotherapy with melphalan plus prednisone has been usedsince the 1960s and is regarded as the standard of care in very elderly patients.
- Trial name
- IFM 01/01 (NCT00644306)
- Testing
- Thalidomide, melphalan, prednisone, melphalan, prednisone, thalidomide
- Where
- France
- Volunteers
- 232 people
- Sponsor
- Central Hospital, Nancy, France