Clinical trials: sponsored by Centre Leon Berard
Breast Cancer
Axillary Sentinel Lymph Node Detection in Breast Cancers > 2 cm
The purpose of this study is to evaluate the quality criteria of the SLN detection technique in breast cancer patients with a tumor size (clinical measurement) greater than 2 centimeters (rate of false negatives, rate of…
- Trial name
- GAS2PLUS (NCT00636467)
- Testing
- No name
- Where
- 22 sites in France
- Volunteers
- 249 people
- Sponsor
- Centre Leon Berard
Prostate Cancer
Carboplatin-Etoposide Combination in Hormone-Resistant Prostate Cancers
The aim of our study is to assess the efficacy and toxicity of a chemotherapy regimen combining carboplatin and etoposide in patients with metastatic hormone-resistant prostate cancer and neuro-endocrine differentiation.
- Trial name
- NCT00973882
- Testing
- Carboplatin, Etoposide
- Where
- 11 sites in France
- Volunteers
- 60 people
- Sponsor
- Centre Leon Berard
Upper Digestive Tract Cancer
Application of Medical Imaging Procedures in Surgery Implanting in Cancerology With the Aim to Reduce Invasive Acts
Aero digestive Cancer patients treated by external head and neck radiotherapy and/or by curie-therapy and/or mandible reconstruction by microanastomosed fibula flaps.
- Trial name
- ATIM (NCT00925509)
- Testing
- Therapeutic assessment -Radio-surgical guidance.
- Where
- 4 sites in France
- Volunteers
- 53 people
- Sponsor
- Centre Leon Berard
Brain and Central Nervous System Tumors
Standard Radiation Therapy, Higher-Dose Radiation Therapy, or Chemotherapy in Treating Older Patients With Glioblastoma Multiforme
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Giving radiation therapy in higher doses over a shorter period of time may kill more tumor cells and have fewer side effects.
- Trial name
- NCT00820963
- Testing
- temozolomide, hypofractionated radiation therapy, radiation therapy
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Centre Leon Berard
Colorectal Cancer
Resorbable Barrier for the Prevention of Abdominal and Peri-hepatic Adhesion Formation
The purpose of this study is to evaluate the efficiency of a resorbable barrier membrane for the prevention of abdominal and peri-hepatic adhesion in patients with colorectal cancer requiring two-stage surgery for the resection…
- Trial name
- SEPRAC2T (NCT01262417)
- Testing
- - use of resorbable membrane Seprafilm, without resorbable barrier (seprafilm)
- Where
- 17 sites in France
- Volunteers
- 60 people
- Sponsor
- Centre Leon Berard
Lymphoma, Myeloma
Stem Cell Mobilization With Pegfilgrastim in Lymphoma and Myeloma
The purpose of this study is to evaluate the efficacy and tolerance of a single administration of Pegfilgrastim in patients with lymphoma or myeloma receiving high-dose chemotherapy and autologous peripheral stem cell support…
- Trial name
- PALM (NCT00794261)
- Testing
- Injection of Pegfilgrastim, Injection of Filgrastim
- Where
- 11 sites in France
- Volunteers
- 150 people
- Sponsor
- Centre Leon Berard
Carcinoma
Evaluation of the Bonfils Fiberscope for Predicted Difficult Intubation in Awake Patients With Ear, Nose, and Throat (ENT) Cancer (INVIBO)
The Bonfils intubation fiberscope (BF), a rigid medical device with a curved tip, is exclusively used in anesthesiology for orotracheal intubation (OTI).
- Trial name
- INVIBO (NCT01070537)
- Testing
- Bonfils fiberscope intubation
- Where
- France
- Volunteers
- 41 people
- Sponsor
- Centre Leon Berard
Breast Cancer
Placebo-controlled Evaluation of Cocculine® Efficacy in the Management of Nausea After Chemotherapy in Breast Cancer.
The purpose of the study is to determine whether a homeopathic remedy (Cocculine®) is effective in the prevention of chemotherapy-induced nausea in non metastatic breast cancer.
- Trial name
- NCT00409071
- Testing
- Cocculine®
- Where
- France
- Volunteers
- 431 people
- Sponsor
- Centre Leon Berard
Spinal Puncture
Randomized Evaluation of a Positioning Pillow for Lumbar Puncture in Paediatric Hematology-Oncology
We have developed a positioning cushion for LP which allows the child to be relaxed in an adequate position, and to maintain this position throughout LP.
- Trial name
- NCT00775112
- Testing
- pillow
- Where
- 2 sites in France
- Volunteers
- 124 people
- Sponsor
- Centre Leon Berard
Metastatic Renal Cell Carcinoma
Cytokines in Patients With Metastatic Renal Cell Carcinoma of Intermediate Prognosis
The PERCY Quattro trial has been designed to evaluate the survival benefit of two cytokine treatments, Interleukin-2 (IL2) and/or alpha interferon (IFN), for patients with intermediate chance of response in metastatic renal cell…
- Trial name
- NCT00291369
- Testing
- Interleukin-2, Interferon alfa, medroxyprogesterone acetate
- Where
- France
- Volunteers
- 456 people
- Sponsor
- Centre Leon Berard