Clinical trials: sponsored by Changhai Hospital
Parkinson Disease, Deep Brain Stimulation
Association Between Fibrinogen-to-albumin Ratio and Delirium After Deep Brain Stimulation Surgery in Parkinson's Disease
Postoperative delirium (POD) remains one of the most common neuropsychiatric complications after deep brain stimulation (DBS) surgery.
- Conditions
- Parkinson Disease, Deep Brain Stimulation, Postoperative Delirium
- Trial name
- NCT05833308
- Where
- China
- Volunteers
- 226 people
- Sponsor
- Changhai Hospital
Pancreatic Exocrine Insufficiency
PE-1 in the Diagnosis of Pancreatic Exocrine Insufficiency
The aim of this study was to evaluate and determine the clinical performance of Fecal Pancreatic Elastase 1 Test in the diagnosis of pancreatic exocrine insufficiency.
- Trial name
- NCT05791110
- Testing
- Fecal pancreatic elastase 1 test
- Where
- China
- Volunteers
- 1,053 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Colon Adenoma
Efficacy of Second Forward-view Examination of Left Colon for Adenoma Detection During Colonoscopy
The incidence of colorectal cancer in China is increasing year by year. Studies have shown that colorectal cancer is more common in the left colon，especially in the China.
- Trial name
- NCT05651893
- Testing
- re-examination, extended withdraw time
- Where
- China
- Volunteers
- 1,516 people
- Sponsor
- Changhai Hospital
Postoperative Delirium, Elderly
The Association Between SIRI and POD in Older Patients
Postoperative delirium (POD) remains one of most common complication in elderly patients receiving surgery, which is characterized by acute and fluctuating change in the level of cognition and consciousness.
- Conditions
- Postoperative Delirium, Elderly, Surgery
- Trial name
- NCT05797194
- Where
- China
- Volunteers
- 116 people
- Sponsor
- Changhai Hospital
Postoperative Complications
Influence of Arrangement of Small Intestine Order on the Recovery of Bowel Function After Laparoscopic Colorectal Surgery
The method of arranging and restoring the position of the small intestine under laparoscopy is used to determine whether it can promote the recovery of intestinal function after colorectal surgery.
- Trial name
- NCT05485857
- Testing
- Arrangement of small intestine order before close the abdomen
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Changhai Hospital
Cerebral Angiography
A Clinical Trial for the Interventional Robotic System
The goal of this multi-center clinical trial is to evaluate the efficacy and safety of the interventional robotic system for cerebral angiography, researchers will compare the ordinary angiography to assess the clinical success…
- Trial name
- NCT05778214
- Testing
- Interventional Robotic System
- Where
- China
- Volunteers
- 142 people
- Sponsor
- Changhai Hospital
Traumatic Lung Injury, Inhalation Injury
Selecting Specific Bio-markers and Researching Mechanisms of Immune Regulation From Inhalation Injury and Traumatic Lung Injury Based on Single Cell Sequencing Technology
The goal of this observational study is to profile the circulating immunological traits of patients with traumatic lung injury (TLI) and inhalation injury (ILI),providing a new direction for the depth research of the…
- Trial name
- NCT05718830
- Where
- China
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
AI Assist in the Diagnosis of Pancreatic Solid Lesions
AI Assisted the Diagnosis of Pancreatic Solid Lesions
Solid lesions of the pancreas mainly include tumor and non tumor lesions. More than 90% of pancreatic tumor lesions are pancreatic cancer, which is characterized by high mortality and poor prognosis and requires surgical…
- Trial name
- NCT05706415
- Testing
- Clinicians will review the suggestions of a hypothetical AI
- Where
- 2 sites in China
- Volunteers
- 200 people
- Sponsor
- Changhai Hospital
Colorectal Cancer, Surgical Procedure, Unspecified
Perioperative Management of Colorectal Cancer Patients Infected With COVID-19: a Multicenter Prospective Cohort Study.
This trial is a multicenter prospective cohort study to explore timing of colorectal cancer surgery after COVID-19 infection so that can assist clinicians and patients.
- Trial name
- NCT05682898
- Testing
- Timing of colorectal cancer surgery
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Digestive Tumor
A Clinical Study on the Safety and Efficacy of CAR-T Therapy for the TM4SF1-positive Tumors of Digestive System
Transmembrane 4 L Six Family Member 1 (TM4SF1) is highly expressed in many tumors of digestive system . The Chimeric Antigen Receptor T-cells (CAR-T) that target TM4SF1 has been generated in our good manufacturing practices (GMP)…
- Trial name
- NCT05673434
- Testing
- TM4SF1-positive chimeric antigen receptor T-cell therapy
- Volunteers
- 24 people
- Sponsor
- Changhai Hospital
IgG4-related Disease
Tofatib Treatment for IgG4-related Disease
Compared with cyclophosphamide, the efficacy and safety of tofacitinib in the treatment of active IgG4-related diseases were evaluated.
- Trial name
- NCT05625581
- Testing
- tofacitinib
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Changhai Hospital
Capsule Endoscopy
Mini-sized MCE for Better Examination of UGI and Small Bowel
A mini-sized MCE highlighted with a diameter of 9.5mm, a length of 24.5mm, and a weight of 3.0g has been developed. This new type of MCE is approximately 0.6 times the conventional MCE (27mm*11.8mm) in volume and weight, and it…
- Trial name
- NCT05073536
- Testing
- mini-sized MCE, normal-sized MCE
- Where
- China
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Anastomotic Leak Rectum
Evaluation of AL Prediction for Rectal Cancer
Anastomotic leakage is one of the most serious postoperative complications of low rectal cancer, with an incidence of 3%-21%. The occurrence of anastomotic leakage is related to many factors, and the occurrence of anastomotic…
- Trial name
- NCT05610904
- Testing
- Prediction model evaluation
- Where
- China
- Volunteers
- 418 people
- Sponsor
- Changhai Hospital
Acute Pancreatitis
Study of Peripheral Blood Non-coding RNAs as Diagnosis and Prognosis Biomarker for Acute Pancreatitis
It is important to identify patients with acute pancreatitis who are at risk for developing persistent organ failure early in the course of disease.
- Trial name
- NCRNAP (NCT02602808)
- Where
- 3 sites in China
- Volunteers
- 1,097 people
- Sponsor
- Changhai Hospital
Pancreatoduodenectomy
Early Oral Feeding for Patients After Pancreaticoduodenectomy
This study intends to retrospectively analyze the patients who underwent pancreatoduodenectomy and compare the safety and feasibility between early enteral nutrition through nasojejunal tube and early oral feeding after…
- Trial name
- NCT05573399
- Where
- China
- Volunteers
- 440 people
- Sponsor
- Changhai Hospital
Small Bowel Disease
Mini-sized MCE for Detection of Small Bowel in Children Under the Age of 10 Years
In this prospective randomized controlled trial, pediatric volunteers were enrolled and randomly underwent mini-sized MCE and normal-sized CE to compare the success rate of self-swallowing between mini-sized MCE and normal-sized…
- Trial name
- NCT05522101
- Testing
- Mini-sized MCE, Normal-sized MCE
- Where
- 4 sites in China
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Esophageal Squamous Cell Carcinoma, Esophageal Cancer
Esophageal cAncer Screening Trial
This multicenter study aims to include 15000 participants undergoing screening upper gastrointestinal endoscopy and establish a risk prediction model for esophageal squamous cell carcinoma and esophagogastric junctional (EGJ)…
- Conditions
- Esophageal Squamous Cell Carcinoma, Esophageal Cancer, Gastroesophageal Junction Adenocarcinoma
- Trial name
- EAST (NCT04609813)
- Testing
- Sponge cytological test
- Where
- China
- Volunteers
- 14,597 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Healthy People, Chronic Pancreatitis
Establishment and Verification of Pancreatic Volume Formula Based on Imaging
This study intends to construct the linear relationship between pancreatic volume and individual attributes (height, weight, width of anterior superior iliac spine, etc.), and to establish and verify the formula of pancreatic…
- Conditions
- Healthy People, Chronic Pancreatitis, Acute Pancreatitis
- Trial name
- NCT05410795
- Testing
- Magnetic resonance imaging
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Changhai Hospital
Pancreatic Stenting, Pancreatic Stent Displacement
Incidence, Risk Factors and Endoscopic Retrieval of Proximally Migrated Pancreatic Stents
This study intends to determine the incidence, risk factors and endoscopic treatment of proximally migrated pancreatic stents.
- Trial name
- NCT05431517
- Testing
- Analysis of ERCP records
- Where
- China
- Volunteers
- 9,073 people
- Sponsor
- Changhai Hospital
Pancreatitis, Chronic, Pancreatic Duct Stone
Comparison of Efficacy of ESWL and Laser Lithotripsy in Chronic Pancreatitis With ERCP
This study will compare the efficacy of ESWL and Laser Lithotripsy in the treatment of pancreatic duct stones with ERCP.
- Trial name
- NCT05326542
- Testing
- ESWL and ERCP, LL and ERCP
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Changhai Hospital