Clinical trials: sponsored by Chinese PLA General Hospital
Intracranial Hemorrhage, Hypertensive
Minimally-invasive Surgery Versus Craniotomy in Patients With Supratentorial Hypertensive Intracerebral Hemorrhage
The effectiveness of craniotomy in the treatment of intracerebral hemorrhage remains controversial. Two main types of minimally invasive surgery, endoscopic evacuation and stereotactic aspiration, have been attempted for hematoma…
- Trial name
- MISICH (NCT02811614)
- Testing
- Endoscopic Evacuation, Stereotactic Aspiration, Craniotomy
- Where
- China
- Volunteers
- 733 people
- Sponsor
- Chinese PLA General Hospital
Ultrafiltration Failure
An Observational Study of Long-term Peritoneal Dialysis Patients Who Eventually Develop Ultrafiltration Failure (LUFF)
At present, there are few researches on peritoneal dialysis, especially on ultrafiltration failure of peritoneal dialysis. To explore the regularity and mechanism of peritoneal ultrafiltration failure,investigators followed up…
- Trial name
- LUFF (NCT05721703)
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Chinese PLA General Hospital
Radiology, Cerebral Stroke
Deep Enhanced Imaging in Stroke and Vascular Neurology
To investigate the performance of enhanced computed tomography (CT) or magnetic resonance (MR) imaging by deep learning relative to conventional CT or MR imaging in brain stroke and vascular neurology.
- Conditions
- Radiology, Cerebral Stroke, Vascular Diseases
- Trial name
- NCT05614193
- Testing
- Deep learning imaging enhancement
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Chinese PLA General Hospital
Pneumocystis Jirovecii Pneumonia
Radiomics Model for the Diagnosis of Pneumocystis Jirovecii Pneumonia in Non-HIV Patients
To evaluate the performance of radiomics in differentiating Pneumocystis jirovecii pneumonia (PCP) from other types of pneumonia and to improve the diagnostic efficacy of non-invasive tests in non-HIV patients.
- Trial name
- NCT05701631
- Testing
- Radiomic model
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Chinese PLA General Hospital
Microbiome,Immune Function, Critically Ill
Microecology and Host Immunity in Patients With Severe COVID-19 Infection
The purpose of this study was to analyze the relationship between the microbial community, host immunity and the prognosis of patients with severe COVID-19.
- Trial name
- NCT05670275
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Chinese PLA General Hospital
Myocardial Infarction, Contrast-induced Nephropathy
Effect of Hydration Guided by Vigileo on the Prevention of CIN After PCI for Patients With AMI
In this study, Vigileo is used to guide hydration adjustment, and SCr is used to estimate renal function. The aim of the study is to investigate the preventive effect of adequate hydration guided by Vigileo on contrast induced…
- Trial name
- NCT04382313
- Testing
- the adequate hydration group guided by Vigileo
- Where
- China
- Volunteers
- 344 people
- Sponsor
- Chinese PLA General Hospital
Moyamoya Disease, Revascularization
The Evolution and Prognosis of Moyamoya Disease
To investigate the evolution of imaging appearances and cognitive function of Moyamoya disease (MMD) and to establish a prognosis evaluation system based on imaging biomarkers in MMD.
- Conditions
- Moyamoya Disease, Revascularization, Cognitive Impairment, Functional Impairment
- Trial name
- NCT05619068
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Chinese PLA General Hospital
Gastric Cancer, Chemotherapy Effect
Neo-adjuvant Chemotherapy Evluation in Gastric Cancer Patients Based on Circulating Exosomal LncRNA-GC1
The investigators hope that through the analysis and research to find determine whether lncRNA-GC1 could serve as a non-invasive biomarker for monitoring the neo-adjuvant chemotherapy response for personalized medicine for…
- Trial name
- NCT05647941
- Testing
- Detection of levels of circulating EV-derived lncRNA-GC1
- Where
- China
- Volunteers
- 700 people
- Sponsor
- Chinese PLA General Hospital
Artificial; Complications, Heart
Stroke Volume Variations and Pulse Pressure Variations Undergoing Artificial Pneumothorax Surgery
Stroke volume variation (SVV) and pulse pressure variation (PPV) have been thought to be sensitive predictors of fluid responsiveness in mechanically ventilated participants.
- Trial name
- NCT05644405
- Testing
- FloTrac Vigileo
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Movement Disorders
Multimodal MR Imaging Study on ET and PD Patients Subjected With MRgFUS Thalamotomy
The technological advance of magnetic resonance-guided focused ultrasound (MRgFUS) has once again brought lesion therapy back to the clinical frontline for the treatment of movement disorder.
- Trial name
- NCT05623644
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Chinese PLA General Hospital
Metabolic-dysfunction-associated Fatty Liver Disease (MAFLD)
Noninvasive Assessment of Metabolic Associated Fatty Liver Disease (MAFLD) in Chinese Population
Attenuation imaging (ATI) technology independently developed by Canon medical is a non-invasive examination technology for quantitative detection and analysis of liver steatosis.
- Trial name
- NCT04551716
- Where
- China
- Volunteers
- 448 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Solid Tumor, Adult, EGFR Overexpression
TGFβR-KO CAR-EGFR T Cells in Previously Treated Advanced EGFR-positive Solid Tumors
Chimeric antigen receptor modified T (CART) cell therapy has been identified as a breakthrough therapy in hematologic malignancies. However, CART cell therapy yielded no satisfactory efficacy data in the study of solid tumors.
- Trial name
- NCT04976218
- Testing
- TGFβR-KO CAR-EGFR T Cells
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Chinese PLA General Hospital
Thrombocytopenia; Drugs, Chronic Liver Disease
Efficacy of Avatrombopag in Thrombocytopenic Patients With Chronic Liver Disease Undergoing an Elective Procedure
In this study, investigators aimed to evaluate the efficacy of Avatrombopag in thrombocytopenic patients with chronic liver disease undergoing an elective invasive procedure through a prospective, non-randomized controlled…
- Trial name
- NCT04915287
- Testing
- Avatrombopag maleate, Platelet transfusion, Medicine
- Where
- China
- Volunteers
- 476 people
- Sponsor
- Chinese PLA General Hospital
Stomach Neoplasms, Neoplasm Metastasis
Gastric Cancer Liver Metastasis Cohort of China
This multi-institutional retrospective cohort study aimed to describe and analyze the overall clinical characteristics, therapeutic status and prognosis pattern of gastric cancer liver metastasis (GCLM) in China.
- Trial name
- RECORD (NCT04574245)
- Testing
- Gastrectomy; Hepatectomy
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Chinese PLA General Hospital
Malignant Solid Tumours
Allogeneic γδ T Cell Therapy for the Treatment of Solid Tumors
The study is to determine the safety, feasibility and efficacy of allogeneic γδ T cell therapy in patients with solid tumors.
- Trial name
- NCT04765462
- Testing
- Allogeneic γδ T cells
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Chinese PLA General Hospital
Chronic Kidney Diseases, Electrolyte Imbalance
24-hour Urinary Electrolyte Excretion in Chronic Kidney Disease
Association between excretion pattern and development trajectory of urinary electrolytes (urine sodium, urine potassium, urine chlorine, urine magnesium, urine calcium, urine phosphorus, urine creatinine, urea, uric acid, urine…
- Trial name
- NCT05550467
- Volunteers
- 10,000 people
- Sponsor
- Chinese PLA General Hospital
Postoperative Acute Kidney Injury
Predictive Nomogram for Postoperative Acute Kidney Injury in Older Patients Undergoing Noncardiac Surgery
Postoperative acute kidney injury is associated increased risk of morbidity and mortality. Older patients are at high risk of developing postoperative acute kidney injury.
- Trial name
- NCT05507268
- Testing
- no intervention
- Where
- China
- Volunteers
- 50,000 people
- Sponsor
- Chinese PLA General Hospital
Arterial Aneurysm
Computational Imaging Research Based on Deep Learning
Computational imaging research based on deep learning
- Trial name
- NCT05471869
- Testing
- Aneurysm diagnosis
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Cerebral Small Vessel Diseases, MRI
Magnetic Resonance Imaging in Cerebral Small Vessel Disease
Cerebral small vessel disease (cSVD) accounts for 20% of ischemic strokes and is the most common cause of vascular cognitive impairment.
- Trial name
- NCT05200377
- Testing
- Magnetic resonance imaging
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Postoperative Delirium
Comparison of Postoperative Delirium in Elders Anaesthetised With Midazolam and Without Midazolam
This research project is an observational cohort study by prospective chart review of patients that underwent surgery in multi-centers, China, in the years 2020-2022.
- Trial name
- NCT05456230
- Testing
- Midazolam
- Where
- China
- Volunteers
- 11,927 people
- Sponsor
- Chinese PLA General Hospital