Clinical trials: completed, sponsored by Emory University
Diabetes
The Effect of Dopamine on Diabetic Retinopathy
The purpose of this study is to evaluate the use of electroretinogram (ERG) using a novel handheld system, RETeval, and evaluate contrast sensitivity testing in detecting pre-clinical retinopathy on a tablet device.
- Trial name
- Dopamine DR (NCT02706977)
- Testing
- Low Dose Sinemet CR, High Dose Sinemet CR, RETeval Electroretinogram (ERG) Testing
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Emory University
Hypertension, Arthritis
The Health Access and Recovery Peer Program
Individuals with serious mental illnesses (SMI) face high rates of medical comorbidity as well as challenges in managing these conditions.
- Conditions
- Hypertension, Arthritis, Coronary Artery Disease, Hepatitis
- Trial name
- HARP (NCT01725815)
- Testing
- HARP Intervention
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Emory University
Coronary Artery Disease
HCR vs. CABG Study
The purpose of the study is to find out if hybrid coronary revascularization (HCR) and coronary artery bypass grafting (CABG) procedure outcomes are similar.
- Trial name
- NCT02892474
- Testing
- Hybrid Coronary Revascularization (HCR), Coronary Artery Bypass Grafting (CABG)
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Emory University
Major Depressive Disorder
Heart Rate Variability in Depression
The purpose of this study is to understand if there is a relationship between the way that emotions are regulated by the brain and the way that heart rate is regulated by the brain.
- Trial name
- NCT02525978
- Testing
- Video Task, Imaginal Task
- Where
- 3 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Emory University
Duarte Galactosemia
Intervention and Outcomes in Duarte Galactosemia
The purpose of this study is to learn about Duarte galactosemia (DG). This study will examine the possible effects of Duarte galactosemia (DG) in children, and determine whether dietary exposure to milk in infancy or early…
- Trial name
- NCT02519504
- Where
- United States
- Volunteers
- 566 people, healthy volunteers welcome
- Sponsor
- Emory University
Prostate Cancer
Fusion Targeted Biopsy of the Prostate
The objective of the proposed study is to evaluate a new, molecular image directed, three-dimensional (3D) ultrasound guided biopsy system in human patients. The current biopsy uses ultrasound imaging as guidance.
- Trial name
- NCT02013414
- Testing
- 3D ultrasound-guided biopsy
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Emory University
HIV Infections
Body Compartment PK for New HIV Pre-exposure Prophylaxis Modalities
The purpose of this study is to determine the ability of new anti-HIV agents to penetrate different body compartments in HIV negative men who have sex with men and transgender women.
- Trial name
- NCT02985996
- Testing
- Truvada, Genvoya
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Emory University
Implantable Cardioverter-defibrillators (ICDs)
Syngery-Evaluating the Impact of Decision Aid
The aim of this study is to determine whether it is better to give patients an implantable cardioverter-defibrillators (ICDs) decision aid before they have their first consultation with an implanting cardiac electrophysiologist…
- Trial name
- NCT03832868
- Testing
- Pre-visit timing of receipt of the ICDs implantation decision aid, Post-visit timing of receipt of the ICDs implantation decision aid
- Where
- 3 sites in United States
- Volunteers
- 25 people
- Sponsor
- Emory University
Schizophrenia
Oxytocin as Adjunctive Treatment of Schizophrenia
The focus of the current project is to advance our understanding of the effects of oxytocin (OT) on components of social cognition in schizophrenia (SCZ).
- Trial name
- NCT01568528
- Testing
- Oxytocin, Control
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Emory University
Pregnancy, Prenatal Care
Perinatal mHealth Intervention in Guatemala
The purpose of the study is to explore ways to improve maternal and child outcomes in the ethnic Maya speaking the Kaqchikel language population, which experiences wide disparities in health care access and outcomes when compared…
- Trial name
- NCT02348840
- Testing
- mHealth
- Where
- Guatemala
- Volunteers
- 843 people, healthy volunteers welcome
- Sponsor
- Emory University
Pain
Gabapentin as an Adjunct to Paracervical Block for Perioperative Pain Management
This is a randomized controlled trial of gabapentin 600 mg compared to placebo given 1-2 hours preoperatively in conjunction with perioperative paracervical block for surgical abortion.
- Trial name
- Gaba (NCT02944656)
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Emory University
Posttraumatic Stress Disorder
Fear Potentiation and Fear Inhibition in Posttraumatic Stress Disorder
The current study will investigate the ability of people with and without fear symptoms after trauma to inhibit fear in an experimental situation.
- Trial name
- NCT00209040
- Testing
- Acoustic Startle Testing
- Where
- United States
- Volunteers
- 425 people, healthy volunteers welcome
- Sponsor
- Emory University
Cocaine-Related Disorders
Acoustic Startle Reduction In Cocaine Dependence
Chronic cocaine administration leads to changes in brain function that persist long after the acute withdrawal phase. The acoustic startle response (ASR) is a well characterized reflexive response to a sudden acoustic stimulus.
- Trial name
- NCT00430690
- Testing
- acoustic startle testing
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Emory University
Schizophrenia
Sensorimotor Gating in Schizophrenia
This study is looking at problems people sometimes have taking in information from their senses. Specifically, we are comparing the way in which people diagnosed with schizophrenia process sound information, compared with people…
- Trial name
- NCT00561561
- Testing
- Acoustic startle testing
- Where
- United States
- Volunteers
- 531 people, healthy volunteers welcome
- Sponsor
- Emory University
Breast Cancer
Inflammation-Induced CNS Glutamate During Breast Cancer Treatment
The purpose of this study is to try and provide data linking the impact of increased inflammatory cytokines as a result of chemotherapy and their relationship with increased levels of CNS glutamate and related behavioral and…
- Trial name
- NCT02421978
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Emory University
Mild Cognitive Impairment
Effects of Atomoxetine in Mild Cognitive Impairment
The purpose of this study is to evaluate the safety of atomoxetine and its effect primarily on the biologic markers (substances that may indicate the presence of a disease) in the cerebrospinal fluid (CSF) of participants…
- Trial name
- ATX-001 (NCT01522404)
- Testing
- Atomoxetine
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Emory University
Latrine Usage
Evaluating a Latrine Use Intervention in Odisha, India
The objective of this research is to evaluate an intervention focused on increasing latrine use in rural Odisha India. The present study builds off of previous research, which resulted in the design of an intervention to increase…
- Trial name
- NCT03274245
- Testing
- Intervention Package, Qualitative Research
- Where
- India
- Volunteers
- 11,722 people
- Sponsor
- Emory University
HIV
Immune Enhancement for Immunological Non-responders to ART
The purpose of this study is to see if taking two nutritional supplements, zinc and SAMe (S-adenosylmethionine), can improve lung health and immune function in persons with HIV.
- Trial name
- IMMUNE (NCT01806870)
- Testing
- Zinc and SAMe
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Emory University
Plantar Fasciitis, Achilles Tendinitis
Effects of Dry Needling Using Spinal and Peripheral Sites Versus Peripheral Sites Only
The purpose of this study is to determine if dry needling both low back and extremity areas is more effective for reducing pain and improving strength, balance and functional performance among patients with chronic…
- Conditions
- Plantar Fasciitis, Achilles Tendinitis, Patellofemoral Pain Syndrome
- Trial name
- NCT02646579
- Testing
- Spinal and Peripheral Dry Needling, Peripheral Dry Needling
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Emory University
Sustained Behavior Change, Mental Well-being
The Impact of Enhanced, Demand-side Sanitation and Hygiene Promotion on Sustained Behavior Change and Health in Ethiopia
This study is a two-year evaluation investigating the impacts of an enhanced, demand-side sanitation and hygiene intervention on sustainable adoption of improved water, sanitation, and hygiene (WASH) practices and mental…
- Trial name
- NCT03075436
- Testing
- Enhanced demand-side sanitation, hygiene, Standard of care
- Where
- Ethiopia
- Volunteers
- 10,375 people, healthy volunteers welcome
- Sponsor
- Emory University