Clinical trials: completed, sponsored by Emory University
Diabetes Mellitus
Satisfaction of Treatment Among Elderly Patients With Insulin Therapy
Several studies have shown that high blood sugar (glucose) levels are associated with diseases caused by diabetes. Controlling the glucose may prevent these complications.
- Trial name
- NCT01240200
- Testing
- Glargine, glargine via insulin pen
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Emory University
Diabetes or With New Hyperglycemia
Trial Between a Computer-Guided Insulin Infusion Protocol Versus a Standard Insulin Infusion Algorithm in Medical ICU
The study is a multicenter, prospective, open-label randomized study to compare the safety and efficacy of continuous insulin infusion (CII) via a computer-guided(Glucommander) and a standard paper form protocol among the…
- Trial name
- NCT00394524
- Testing
- Glucommander, Standard insulin infusion algorithm
- Where
- 4 sites in United States
- Volunteers
- 160 people
- Sponsor
- Emory University
Neuroendocrine Tumors
Pasireotide, Everolimus and Selective Internal Radioembolization Therapy for Unresectable Hepatic Metastases
The purpose of this study is to see the safety and activity of using pasireotide, everolimus and radioembolization (Selective Internal Radioembolization Therapy-SIRT) in the treatment of neuroendocrine tumors (carcinoid) that has…
- Trial name
- NCT01469572
- Testing
- Pasireotide, Sir-sphere Radioembolization, Everolimus
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Emory University
Parenteral Nutrition
Study Comparing a Soybean Oil-Based With an Olive Oil-Based Lipid Emulsion in ICU Patients Requiring TPN
Many hospitalized patients who are malnourished or not eating receive intravenous feeding or total parenteral nutrition (TPN). Despite improving nutrition, TPN may increase the risk of infections and hospital complications.
- Trial name
- TPN2 (NCT00672854)
- Testing
- ClinOleic 20% Intravenous Emulsion, Intralipid, 20% Intravenous Emulsion
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Emory University
Endothelial Dysfunction, Hypertension
FFA-Induced Hypertension and Endothelial Dysfunction
The study is a prospective open label study to examine the effects of oral and intravenous fat load on blood pressure, endothelial function, sympathetic activity, and oxidative stress in obese healthy subjects.
- Trial name
- NCT00589888
- Testing
- Intralipid 20% @ 20cc/hour, Intralipid 20%@ 40cc/hour, Normal Saline
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Emory University
Diabetes Mellitus, Type 2
Mechanism Underlying Beta-cell Failure in Obese African Americans With History of Hyperglycemic Crises
Obesity is common in African American (AA) patients with newly diagnosed diabetes who present with diabetic ketoacidosis (DKA). Despite the presentation with severe symptoms of insulinopenia and ketoacidosis, clinical and…
- Trial name
- NCT00753142
- Testing
- Intralipid 20%, Glucose infusion
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Emory University
Sickle Cell Disease, Sickle Cell Anemia
Decision Aid for Therapeutic Options In Sickle Cell Disease
Sickle cell disease (SCD) is an inherited disorder with chronic multi-system manifestations affecting 100,000 individuals in the US, largely of minority origin and associated with substantial morbidity, premature mortality…
- Conditions
- Sickle Cell Disease, Sickle Cell Anemia, Hemoglobin SS, Hemoglobin SC
- Trial name
- NCT02326597
- Testing
- Decision Aid Tool, Standard Practice
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Emory University
Pneumococcal Infection
Systems Biology of PNEUMOVAX®23 and PREVNAR 13®
Vaccination is the most effective way of preventing infectious diseases. Despite the success of vaccines in general, vaccines induce diminished antibody responses and lower protection in the elderly in particular.
- Trial name
- NCT01307449
- Testing
- PNEUMOVAX, Prevnar
- Where
- 2 sites in United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Emory University
Inflammatory Bowel Disease, Crohn's Disease
Medication Adherence in Patients With Inflammatory Bowel Disease (IBD)
The purpose of this is to formally assess health literacy and medication adherence in participants with Inflammatory bowel disease (IBD).
- Conditions
- Inflammatory Bowel Disease, Crohn's Disease, Ulcerative Colitis
- Trial name
- NCT02620514
- Testing
- Education and Reminders, Educational Visit, Medication Educational Visit
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Emory University
Diabetic Ketoacidosis
Basal Insulin in the Management of Patients With Diabetic Ketoacidosis (DKA)
The study is a multicenter, randomized controlled trial to compare the safety and efficacy of insulin analogs and human insulins both during acute intravenous treatment and during the transition to subcutaneous insulin in…
- Trial name
- NCT00590044
- Testing
- insulin glargine+ glulisine, NPH + Regular insulin
- Where
- 2 sites in United States
- Volunteers
- 74 people
- Sponsor
- Emory University
Schizophrenia, Schizoaffective Disorder
Minocycline Augmentation to Clozapine
The proposed pilot study will compare minocycline augmentation with clozapine in individuals with high vs low inflammation as measured by CRP.
- Trial name
- NCT02124811
- Testing
- Minocycline
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Emory University
Poor Glycemic Control
Efficacy and Safety of a Glargine-based Hospital Discharge Algorithm in Coronary Artery Bypass Graft (CABG) Patients
Most coronary artery bypass graft surgery (CABG) patients develop high blood sugar while they are in the hospital. No studies have shown what the best insulin regimen is for CABG patients with type 2 diabetes is after going home…
- Trial name
- CABG-D/C (NCT01792830)
- Testing
- Metformin, Glargine insulin, Glulisine
- Where
- 3 sites in United States
- Volunteers
- 175 people
- Sponsor
- Emory University
HIV
Comprehensive HIV Prevention Package for MSM in Southern Africa: Pilot Study (Sibanye Health Project)
The purpose of this study is to evaluate the acceptability and uptake of a combination package of biomedical, behavioral and community-level HIV prevention interventions and services for men who have sex with men (MSM) in South…
- Trial name
- NCT02043015
- Testing
- Condom choices, Condom-compatible lubricant choices, Couples HIV counseling and testing (CVCT)
- Where
- 3 sites in United States, South Africa
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Emory University
Depression
Effectiveness of Escitalopram in Preventing or Reducing Depressive Symptoms in People Receiving Interleukin-2 Treatment
This study will determine the effectiveness of an antidepressant in preventing or reducing depressive symptoms in people with melanoma who are receiving Interleukin-2 (IL-2) treatment.
- Trial name
- NCT00352885
- Testing
- Escitalopram, IL-2
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Emory University
Diabetes
ADA Linagliptin in Long Term Care
This is a study to determine whether glycemic control, as measured by change in HbA1c and frequency of hypoglycemia, is different between treatment with linagliptin (Tradjenta®) and basal insulin in long term care residents(LTC)…
- Trial name
- NCT02061969
- Testing
- linagliptin, insulin glargine
- Where
- 4 sites in United States
- Volunteers
- 140 people
- Sponsor
- Emory University
Influenza
Systems Biology of Flu Vaccine in Healthy Adults With and Without the Use of Antibiotics
The purpose of the study is to better understand how the use of antibiotics changes micro-organisms in the intestines. The change to micro-organisms in the intestines may change the body's vaccine immune response and alter the…
- Trial name
- VAX-002 (NCT02154061)
- Testing
- IIV Flu Vaccine, Metronidazole, Neomycin
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Emory University
Chronic Pruritus
Study of Kids Itch Severity (SKIS)
This purpose of this study is to validate two measures of chronic itching in kids: itch severity (ItchyQuant) and the impact on their quality of life (ItchyQoL).
- Trial name
- SKIS (NCT02672579)
- Where
- United States
- Volunteers
- 312 people
- Sponsor
- Emory University
Cancer
Promoting Quality of Life Among Young Adult Cancer Survivors
This study expands on a prior pilot study to refine the intervention messaging to focus on goal-oriented thinking, include a coach, and extend the intervention to a larger sample of young adult cancer survivors (aged 18-39 years)…
- Trial name
- NCT03446105
- Testing
- App-based behavioral intervention, Attention control group
- Where
- 2 sites in United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Emory University
Human Papilloma Virus
PreTeenVax Evaluation
The primary research aim of this project is to test the effectiveness of a comprehensive, evidence-based vaccine promotion toolkit implemented in the pediatric healthcare setting on increasing the likelihood that adolescents in…
- Trial name
- NCT03186430
- Testing
- Comprehensive Vaccine Promotion Package
- Where
- 6 sites in United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Emory University
HIV Associated Neurocognitive Disorder, Human Immunodeficiency Virus
Observational Study of HIV-associated Neurocognitive Disorder
It is estimated that over 1 million people in the United States have HIV infection. While HIV is treatable, there are still high rates of HIV-associated neurocognitive disorder (HAND).
- Trial name
- HAND2 (NCT01966094)
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Emory University