Clinical trials: completed, sponsored by Emory University
Childhood Vaccinations
Tailoring of Vaccine-Focused Messages: Moral Foundations
This study is the first phase of a trial examining decision making about vaccines. This phase tests the impact of targeted vaccine-focused health messages on vaccine beliefs held by parents of young children and pre-adolescents.
- Trial name
- NCT02851459
- Testing
- Baseline Survey, Pre-intervention Survey, Morally Congruent Message
- Where
- United States
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- Emory University
Malignant Neoplasm
Potential Use of Indocyanine Green as a Fluorescent Agent for Definition of Surgical Margins in Cancer
The surgeon may remove a very small amount of additional tissue compared to what would be removed if you were not enrolled in the study. This tissue may prove to contain tumor or it may contain normal tissue.
- Trial name
- NCT01884584
- Testing
- Indocyanine green (ICG)
- Where
- 3 sites in United States
- Volunteers
- 24 people
- Sponsor
- Emory University
Stress Disorders, Post-Traumatic
Evaluation of GSK561679 in Women With Post-Traumatic Stress Disorder
This study will test the hypothesis of whether an antagonist at the corticotropin releasing factor type 1 (CRF1) receptor (i.e. GSK561679) is superior to placebo in reducing symptoms of post-traumatic stress disorder (PTSD).
- Trial name
- NCT01018992
- Testing
- GSK561679
- Where
- 4 sites in United States
- Volunteers
- 267 people
- Sponsor
- Emory University
Posttraumatic Stress Disorder (PTSD)
Effects of Paxil CR on Neural Circuits in Posttraumatic Stress Disorder (PTSD)
Posttraumatic stress disorder (PTSD) is a major public health problem in this country. It is estimated that at least one out of every seven women in our society have been the victim of childhood sexual abuse at least once before…
- Trial name
- NCT00672776
- Testing
- paroxetine
- Volunteers
- 40 people
- Sponsor
- Emory University
Health Promotion
Caregiver Stress: Interventions to Promote Health and Wellbeing
More and more family members are providing care to their loved ones with prolonged and progressive illnesses. Chronic intense caregiving represents a situation of chronic stress, which takes a toll on one's mental and physical…
- Trial name
- NCT01188070
- Testing
- Usual Care, Psycho-education, Psycho-education plus physical exercise
- Where
- United States
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- Emory University
HIV, AIDS
Exploring the Impact of HIV and ART on Knowledge, Attitudes and Practices in Reproductive Health in Lilongwe, Malawi
The aim of this study is to identify reproductive health priorities among individuals living with HIV.This study also seeks to explore factors that influence fertility, family planning, and sexual behavior among individuals with…
- Trial name
- HIV KAP (NCT02667808)
- Testing
- Focus Group, Questionnaire
- Where
- Malawi
- Volunteers
- 562 people
- Sponsor
- Emory University
Neoplasms, Malignancies
Extended Infusion Carfilzomib on a Weekly Schedule in Patients With Advanced Solid Tumors
The purpose of this study is to find the safest dose level of an approved drug, carfilzomib, in solid tumors when given over a different period of time than normally used.
- Trial name
- NCT02257476
- Testing
- Carfilzomib, Dexamethasone
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Emory University
Orthopedic Disorders, Tibial Fractures
Reliability of Sensor Spacing for NIRS in Traumatic Tibia Fractures
This is a study intended to evaluate a non-invasive device that uses light to measure the amount of oxygen in the muscles of injured and non-injured legs in specific situations.
- Trial name
- NCT02301832
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Emory University
Fear of Flying
Targeting Reconsolidation to Prevent Return of Fear
The overall aim of this project is to determine if using a cue to trigger (and reactivate) the fear memory 10 minutes prior to exposure treatment sessions leads to less anxiety in patients with a fear of flying.
- Trial name
- NCT01623830
- Testing
- Virtual Reality Exposure Therapy
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Emory University
Human Immunodeficiency Virus
Cognitive-Based Compassion Training (CBCT) for People Living With HIV (PLHIV)
The purpose of the study is to examine the effects of cognitive-based compassion training (CBCT), a meditative practice based on Buddhist teachings, on long term emotional well-being and immune system improvement with people…
- Trial name
- NCT02395289
- Testing
- Cognitive-Based Compassion Training (CBCT), Health discussion
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Emory University
Right Ventricle, Pulmonary Valve Stenosis
Follow Up on Freestyle Valves in Children
The purpose of this study is to determine if the Medtronic Freestyle porcine valve is effective over a long period of time when it is used to replace the valve that normally allows blood to flow from the right lower pumping…
- Conditions
- Right Ventricle, Pulmonary Valve Stenosis, Pulmonary Valve Atresia
- Trial name
- NCT00385112
- Testing
- Echocardiogram
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Emory University
Stroke
Stroke Study: Operative Strategies to Reduce Cerebral Embolic Events During Coronary Artery Bypass Surgery
One of the most devastating complications of coronary artery bypass surgery (CABG) is postoperative stroke. While there are multiple causes of stroke after CABG, particles generated during handling of the aorta is believed to…
- Trial name
- NCT01502683
- Testing
- No aortic clamping, partial occluding clamp, single cross clamp
- Where
- United States
- Volunteers
- 193 people
- Sponsor
- Emory University
HIV
Planning for SUCCESS
Planning for SUCCESS (Sustained, Unbroken Connections to Care, Entry Services, and Suppression) is a project to improve the connection to community care for HIV infected persons leaving Fulton County Jail or Atlanta City…
- Trial name
- SUCCESS (NCT02185742)
- Testing
- Strength Based Case Management
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- Emory University
Respiratory Failure
Vitamin D in Ventilated ICU Patients
The increasing rate of hospital-acquired infection and antibiotic resistance are major causes of prolonged ICU stay and death in hospitalized patients.
- Trial name
- R21 HL-110044 (NCT01372995)
- Testing
- Enteral Vitamin D3 50,000 IU, Enteral Vitamin D3 100,000IU, Inactive substance
- Where
- 2 sites in United States
- Volunteers
- 31 people
- Sponsor
- Emory University
Lung Cancer
Trial of RAD001 in Patients With Operable Non-Small Cell Lung Cancer (NSCLC)
This is a Phase 1b pre-operative lung cancer trial wherein patients with operable lung cancer will be treated with RAD001 to evaluate the target effects of this compounds on relevant molecular pathways and on the…
- Trial name
- NCT00401778
- Testing
- RAD001
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Emory University
Colorectal Adenomatous Polyps
Calcium/Vitamin D, Biomarkers & Colon Polyp Prevention
The study team has developed a set of biomarkers of risk for colon cancer; this study tests 1) whether or not calcium and/or vitamin D supplementation can favorably affect these biomarkers in persons who are at higher than…
- Trial name
- PPS4B (NCT00399607)
- Testing
- Rectal biopsy during colonoscopy, Rectal biopsy at randomization, Rectal biopsy at 1 year
- Where
- 9 sites in United States
- Volunteers
- 264 people
- Sponsor
- Emory University
Autism Spectrum Disorder
Emergence of Generative Language
The purpose of this study is to investigate the effects of several applied behavior teaching procedures on the use of multi-word utterances by children with autism.
- Trial name
- NCT02555241
- Testing
- Mand Training, Matrix, Stimulus Equivalence Training
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Emory University
Heart Diseases
B-type Natriuretic Peptide in the Non-Cardiac Pediatric Patient
B-type Natriuretic Peptide (BNP) is a hormone that is made by the pumping chambers of the heart. The BNP level can be measured by a blood test and is used as a marker for heart problems in adults.
- Trial name
- NCT00330811
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Emory University
Atrial Fibrillation, Coronary Artery Disease
Management of New-Onset Postoperative Atrial Fibrillation
One common occurrence following open heart surgery is an irregular rhythm from the top chambers of the heart known as atrial fibrillation (afib or AF).
- Conditions
- Atrial Fibrillation, Coronary Artery Disease, Post Operative Arrythmia
- Trial name
- Monitor-AF (NCT01395836)
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Emory University
Diabetes Mellitus, Type 2
A Randomized Trial of Diabetes Prevention Through Lifestyle Change in India
People from the Indian subcontinent are more likely to get diabetes, even at younger ages. The Diabetes Community Lifestyle Improvement Program (D-CLIP) will test in a randomized trial if a culturally specific, community-based…
- Trial name
- D-CLIP (NCT01283308)
- Testing
- Lifestyle Intervention, Standard of Care
- Where
- India
- Volunteers
- 599 people, healthy volunteers welcome
- Sponsor
- Emory University