Clinical trials: sponsored by Fujian Medical University
Cardiovascular Diseases (CVD), Postoperative
Evaluate the Value of Modified Shock Index in Predicting the Incidence of Cardiovascular Events After Non-cardiac Surgery in Cardiac Patients
The objective of this study is to evaluate the efficacy of the modified shock index (MSI) in predicting the incidence of postoperative cardiovascular events (PCEs) in patients with pre-existing cardiac disease undergoing…
- Trial name
- NCT07735689
- Volunteers
- 1,500 people
- Sponsor
- Fujian Medical University Union Hospital
Tumor, Positron-Emission Tomography
68Ga-FAPI PET/CT in Patients With Various Types of Cancer
To evaluate the potential usefulness of 68Ga-DOTA/NOTA-FAPI-04 positron emission tomography/computed tomography (PET/CT) for the diagnosis of primary and metastatic lesions in various types of cancer.
- Conditions
- Tumor, Positron-Emission Tomography, Metastasis
- Trial name
- NCT04499365
- Testing
- 68Ga-DOTA/NOTA-FAPI-04, PET/CT scan
- Where
- China
- Volunteers
- 500 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Lymphoma, Multiple Myeloma
Value of Chemokine Receptor CXCR4 Imaging for Diagnosis and Prognostic Evaluation in Lymphoproliferative Diseases
Chemokine receptor CXCR4 is normally expressed on T-lymphocytes, B-lymphocytes, monocytes, macrophages, neutrophils and eosinophils as well as hematopoietic stem and progenitor cells (HSPC) in the bone marrow.
- Conditions
- Lymphoma, Multiple Myeloma, Leukemia
- Trial name
- NCT04504526
- Testing
- 68Ga-Pentixafor
- Where
- China
- Volunteers
- 50 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Positron-Emission Tomography
Application of 68Ga-Pentixafor PET/CT in Primary Aldosteronism and Pre-postoperative of SAAE
Primary aldosteronism is the most common cause of secondary hypertension. The two main types of primary aldosteronism are aldosteronoma(30%) and adrenal hyperplasia(60%).
- Trial name
- NCT05188872
- Testing
- 68Ga-Pentixafor
- Where
- China
- Volunteers
- 100 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Elderly Heart Valve Surgery, Silent Aspiration
Study on Influencing Factors and Intervention of Silent Aspiration After Heart Valve Operation in Elderly Patients
Objective To investigate the safety and effectiveness of interference electrical stimulation in the prevention of silent aspiration after heart valve surgery in elderly patients.
- Trial name
- SILENT-HV (NCT07710001)
- Testing
- The intervention was delivered using the Gentle Stim Electrical Stimulation Therapy Device (Model: JC-2071), Usual Care Group
- Where
- China
- Volunteers
- 117 people
- Sponsor
- Fujian Medical University Union Hospital
Radiation Cystitis
Clinical Efficacy of Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Combined With Sodium Hyaluronate Intravesical Instillation in the Treatment of Radiation Cystitis
The goal of this clinical trial is to learn whether intravesical instillation of human umbilical cord mesenchymal stem cell-derived exosomes combined with sodium hyaluronate is safe and effective for treating radiation cystitis.
- Trial name
- NCT07665619
- Testing
- Exosomes (hUC-MSC-Exo), Sodium Hyaluronate (Hyalein), Normal Saline (0.9% NaCl)
- Volunteers
- 48 people
- Sponsor
- Fujian Medical University Union Hospital
Prostate Cancer, Biochemical Recurrence
Predictors of BCR After RARP for Localized Prostate Cancer: A Retrospective Analysis
This retrospective study aims to identify predictive factors for biochemical recurrence (BCR) in patients with localized prostate cancer who underwent robot-assisted radical prostatectomy (RARP).
- Trial name
- NCT07682584
- Volunteers
- 200 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Patients With Advanced Metastatic FAP-Positive Tumors
Clinical Study of 177Lu-JH040182 in Patients With FAP-Positive Malignancies
This first-in-human study aimed to assess the safety and internal radiation dosimetry of 177Lu-JH040182, a novel FAP-targeted radiopharmaceutical, in patients with FAP-positive tumors.
- Trial name
- NCT07681141
- Testing
- 177Lu-JH040182 with an activity of approximately 5.55-7.50 GBq
- Where
- China
- Volunteers
- 3 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Keloid
A Clinical Study on the Safety and Efficacy of Wide-Band Ultrasound Combined With Traditional Chinese Medicine Preparations in the Prevention and Treatment of Keloids
The prevention and treatment of patients with multiple keloids throughout the body are extremely challenging. Keloids are highly resistant, refractory, and prone to recurrence, and are thus known as the "cancer that does not…
- Trial name
- WBUS +TCM (NCT07679243)
- Testing
- Wide-Band Ultrasound, traditional Chinese medicine
- Volunteers
- 120 people
- Sponsor
- Fujian Medical University Union Hospital
PARKINSON DISEASE (Disorder)
Integrated Digital and Neurogenic Exosome Biomarkers for Early Diagnosis of Parkinson's Disease: Development and Application
Based on the high-quality Parkinson's disease cohort population and biological sample database in the early stage of the team, multi-dimensional intelligent wearable device technology and machine learning were used to screen and…
- Trial name
- NCT07679256
- Where
- China
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University Union Hospital
Complicated Intra-abdominal Infection (cIAI), Systemic Inflammatory Response
Ulinastatin on Systemic Immune-Inflammation in Patients With Complicated Intra-Abdominal Infection
Complicated intra-abdominal infection (cIAI) triggers dysregulated systemic inflammation and immune paralysis leading to high organ failure and death risk.
- Conditions
- Complicated Intra-abdominal Infection (cIAI), Systemic Inflammatory Response, Sepsis, Immune Dysfunction
- Trial name
- UTI-cIAI (NCT07672496)
- Testing
- ulinastatin, Normal Saline (0.9% NaCl)
- Where
- China
- Volunteers
- 165 people
- Sponsor
- Fujian Medical University Union Hospital
Colon Cancer, Synchronous Liver Metastases
QL1706 Combined With Standard Therapy for Conversion Therapy of Synchronous Liver Metastases From Colon Cancer: a Multicenter, Single-arm, Exploratory Study
This is a single-arm clinical study aiming to enroll 30 colon cancer patients with liver-only metastases. All eligible participants will undergo screening and enrollment after signing the informed consent form.
- Trial name
- NCT07649473
- Testing
- QL1706 (Iparomlimab/Tuvonralimab)
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Fujian Medical University
MDS (Myelodysplastic Syndrome), AML (Acute Myeloid Leukemia)
Haplo-Cord HSCT for AML/MDS
This study aims to investigate the clinical efficacy of haploidentical-cord blood hematopoietic stem cell transplantation in patients with acute myeloid leukemia (AML) and high-risk myelodysplastic syndromes (MDS), and to analyze…
- Trial name
- NCT07588360
- Testing
- haplo-cord HSCT, Fludarabine, Cytarabine, Busulfan, Antithymocyte Globulin (ATG), Melphalan, Cyclophosphamide (CTX)
- Where
- 4 sites in China
- Volunteers
- 82 people
- Sponsor
- Fujian Medical University Union Hospital
Thyroid Diseases, Thyroid Neoplasms
Computer Vision-Based Recognition of Parathyroid Glands and Recurrent Laryngeal Nerves in Endoscopic Surgery
This study aims to evaluate the performance of the PTAIR computer vision model for recognizing parathyroid glands and recurrent laryngeal nerves during endoscopic thyroid surgery.
- Trial name
- PTAIR (NCT07628543)
- Testing
- PTAIR Computer Vision Model Assessment
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Fujian Medical University
Dementia, Primary Health Care Providers
Dementia Management Training Programme for Primary Health Care Providers
This study aims to evaluate the effectiveness and implementation outcomes of a dementia management competency training program for primary healthcare workers.
- Trial name
- NCT07617883
- Testing
- Structured Dementia Management Competency Training Program, Self-directed Dementia Learning
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University
BPH (Benign Prostatic Hyperplasia)
Predicting BPH Surgery Outcomes Using a Preoperative Scoring System
This study aims to develop and validate a preoperative predictive scoring system for surgical outcomes in patients with benign prostatic hyperplasia (BPH) undergoing prostate surgery (including but not limited to transurethral…
- Trial name
- NCT07623239
- Volunteers
- 2,000 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Urinary Bladder Neoplasms
FAPI and FDG PET/MRI in Diagnosis and Therapy Prediction of Bladder Cancer
The aim of this trial is to investigate the value of FAPI PET/MRI, FDG PET/MRI and MRI in diagnosing MIBC and predicting the efficacy of neoadjuvant therapy for MIBC patients, so as to guide the clinic to adjust the treatment…
- Trial name
- NCT06421142
- Testing
- imaging examinations:FAPI PET/MRI, FDG PET/MRI, MRI
- Where
- China
- Volunteers
- 80 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Prostate Cancer Screening, PSMA-PET
PSMA PET/MRI-Guided Prostate Biopsy for PI-RADS ≤3 and Prior Negative Biopsy
The goal is to provide more accurate diagnostic tools and optimized diagnostic workflows for clinically suspected prostate cancer patients with prior negative biopsies, improving early detection rates for csPCa and reducing…
- Trial name
- NCT06923657
- Testing
- PSMA PET/MRI-TRUS guided prostate targeted combined saturation biopsy, TRUS guided transperineal saturation biopsy
- Where
- China
- Volunteers
- 230 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Parkinson Disease (PD)
A Multimodal Convergent Cohort of Parkinson's Disease at FJMUUH (FJMUUH-PD): Natural History Study
Parkinson's disease (PD) is a common neurodegenerative disorder in middle-aged and elderly individuals, with a global incidence of 2.0% among adults aged 65 and over.
- Trial name
- NCT07588763
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Fujian Medical University Union Hospital
Creutzfeldt-Jakob Disease (CJD) | Prion Disease
CLIME-CJD: A Multimodal Study
Creutzfeldt-Jakob disease (CJD) is a rare and rapidly progressive neurological disorder. This study aims to describe and summarize the key features of CJD by looking back at medical records of patients who were diagnosed with CJD…
- Trial name
- NCT07589283
- Testing
- No Interventions
- Where
- China
- Volunteers
- 150 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University