Clinical trials: sponsored by Fujian Medical University
Breast Cancer Surgery, Neoadjuvant Therapy
Application of Targeted Axillary Lymph Node Resection in Axillary Surgery After Neoadjuvant Chemotherapy for Breast Cancer: an Open-label, Multicenter Study
In this study, following the full informed consent of patients regarding the safety and potential benefits of the new intervention regimen, pathologically confirmed lymph nodes were pre-labeled with carbon nanoparticles prior to…
- Conditions
- Breast Cancer Surgery, Neoadjuvant Therapy, Sentinel Lymph Node Biopsy (SLNB)
- Trial name
- NCT07032220
- Testing
- carbon suspension
- Where
- China
- Volunteers
- 175 people
- Sponsor
- Fujian Medical University Union Hospital
Lung Cancer Patients
Tubeless Anesthesia in Preventing Lung Complications in Patients Undergoing Surgery for Early-Stage Lung Cancer
The study focuses on evaluating the effectiveness and safety of tubeless anesthesia in single-port thoracoscopic surgery for early-stage lung cancer patients.
- Trial name
- NCT07024433
- Testing
- Tubeless anesthesia, Traditional tracheal intubation
- Where
- China
- Volunteers
- 224 people
- Sponsor
- Fujian Medical University Union Hospital
PCI Patients, DAPT(Dual Antiplatelet Therapy)
Comparison of Cardiovascular Risks Between Hip Fracture Surgery With Continued DAPT（Dual Antiplatelet Therapy ） Within 6 Weeks vs After 6 Weeks Post-PCI（Percutaneous Coronary Intervention）: A Prospective Observational Cohort Study
Percutaneous coronary intervention (PCI) is commonly used to treat stable ischemic heart disease. Among patients, 7.5% require surgical treatment, and up to 20% may need noncardiac surgery (NCS) within two years.
- Conditions
- PCI Patients, DAPT(Dual Antiplatelet Therapy), Hip Fracture Surgeries
- Trial name
- NCT07024446
- Testing
- The time interval between PCI and NCS
- Volunteers
- 50 people
- Sponsor
- Fujian Medical University Union Hospital
Gastrectomy for Gastric Cancer, Robotic Surgical Procedures
Assessment of Robotic Versus Laparoscopic Gastrectomy for GC Patients With Intraoperative Technical Complexity
While robotic gastrectomy (RG) is increasingly used in gastric cancer surgery, its potential advantages over laparoscopic gastrectomy (LG) in Intraoperative technical complexity (ITC) cases remain debated.
- Conditions
- Gastrectomy for Gastric Cancer, Robotic Surgical Procedures, Laparoscopic Surgical Procedures
- Trial name
- NCT06752538
- Where
- China
- Volunteers
- 3,534 people
- Sponsor
- Fujian Medical University
Thyroid Neoplasms
Genotype-Driven Neoadjuvant Therapy for Locally Advanced Thyroid Cancer: A Real-World Cohort Study
This multicenter registry tests whether genomically matched neoadjuvant therapy (1-4 cycles tailored to BRAF V600E, RET fusion/mutation, isolated TERT mutation, triple-negative BRAF/RET/TERT, or ICI ± TKI) can render locally…
- Trial name
- NCT07010393
- Testing
- Dabrafenib, Trametinib, Selpercatinib
- Where
- China
- Volunteers
- 335 people
- Sponsor
- Fujian Medical University
Breast Cancer
A Study on the Efficacy and Safety of IPyC for HER2+ MBC
Between July 2020 and August 2024, 301 HER2-positive MBC patients from five tertiary centers received the regimen until disease progression or unacceptable toxicity.
- Trial name
- NCT06990347
- Testing
- Inetetamab and Pyrotinib Combined with Chemotherapy
- Where
- China
- Volunteers
- 301 people
- Sponsor
- Fujian Medical University
Thyroid Cancer, Thyroid Cancer, Papillary
Intraoperative Neuromuscular Monitoring and Its Impact on Pre- and Postoperative Acoustic Outcomes in Thyroid Surgery
This study examines the impact of intraoperative recurrent laryngeal nerve monitoring signal changes on the postoperative voice quality of thyroid surgery patients.
- Trial name
- NCT06254859
- Testing
- Traditional thyroid surgery.
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Fujian Medical University
Myotonic Dystrophy Type 1 (DM1)
A Registered Observational Cohort Study of Myotonic Dystrophy Type 1
Myotonic dystrophy type 1 (DM1) is the most common form of muscular dystrophy.There is little phenotype and genetic data for Chinese DM1 patients.
- Trial name
- NCT06979024
- Testing
- Triplet-primed PCR or Long-read sequencing
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Robotic-Assisted Radical Prostatectomy, Locally Advanced Prostate Cancer
Improved Robotic-Assisted Radical Prostatectomy for Locally Advanced Prostate Cancer: Bladder Suspension and Preliminary Outcomes
This study is a prospective, single-center clinical trial. It aims to establish an improved robotic-assisted radical prostatectomy for treating locally advanced prostate cancer.
- Conditions
- Robotic-Assisted Radical Prostatectomy, Locally Advanced Prostate Cancer, Bladder Suspension
- Trial name
- NCT06977906
- Testing
- conventional Robotic-assisted radical prostatectomy group, Improved Robotic-assisted radical prostatectomy group
- Where
- China
- Volunteers
- 300 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Hepatocellular Carcinoma
A Trial of Cadonilimab Plus Regorafenib in Patients With Hepatocellular Carcinoma Who Failed Camrelizumab Combined With Apatinib
To evaluate the efficacy and safety of cadonilimab combined with Regorafenib in patients with hepatocellular carcinoma who failed camrelizumab plus apatinib.
- Trial name
- NCT06280105
- Testing
- Cadonilimab+regorafenib
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Meng Chao Hepatobiliary Hospital of Fujian Medical University
Hepatocellular Carcinoma
A Real-world Study of Camrelizumab Combined With Apatinib Mesylate in Unresectable Hepatocellular Carcinoma
To evaluate the efficacy and safety of camrelizumab combined with apatinib mesylate in the treatment of unresectable hepatocellular carcinoma.
- Trial name
- NCT05409482
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Meng Chao Hepatobiliary Hospital of Fujian Medical University
Gastric Cancer, Surgery
Clinical Outcomes of Indocyanine Green Tracer Using in Laparoscopic Gastrectomy With Extended Lymphadenectomy Beyond D2 for Locally Advanced Gastric Cancer (FUGES-30)
Taking patients with locally advanced gastric adenocarcinoma (cT2-4a, N-/+, M0) as the research subjects, to evaluate whether the clinical efficacy of laparoscopic beyond D2 regional lymph node dissection for gastric cancer with…
- Trial name
- NCT06945718
- Testing
- beyond D2 regional lymph node dissection
- Where
- China
- Volunteers
- 760 people
- Sponsor
- Fujian Medical University
Stomach Neoplasms, Indocyanine Green
Indocyanine Green Tracer Using in Laparoscopic Gastrectomy With Lymph Node Dissection
The purpose of this study is to explore the clinical outcomes of Indocyanine Green Tracer using in laparoscopic gastrectomy with lymph node dissection for gastric adenocarcinoma（cT1-4a, N-/+, M0）.
- Trial name
- ICGTinLG (NCT03050879)
- Testing
- Indocyanine Green Tracer
- Where
- China
- Volunteers
- 266 people
- Sponsor
- Fujian Medical University
Advanced Gastric Cancer
Potential Advantages of Robotic Total Gastrectomy in Advanced Middle-Upper Gastric Cancer: A Multicenter Propensity Score Matching Analysis
This multicenter retrospective cohort study aimed to evaluate the potential advantages of robotic total gastrectomy (RTG) compared to laparoscopic total gastrectomy (LTG) in patients with advanced middle and upper gastric cancer…
- Trial name
- NCT06941168
- Testing
- Robotic Total Gastrectomy and Laparoscopic Total Gastrectomy
- Where
- China
- Volunteers
- 1,099 people
- Sponsor
- Fujian Medical University
Gastric Adenocarcinoma, Surgery, Laparoscopic
Defining Benchmarks for Gastric Cancer Patients Underwent Minimal Invasive Gastrectomy
The Benchmark-MISGC study was a large-scale retrospective observational study launched by the China Gastric Cancer Surgical Union, aiming to establish the benchmarks of the short- and long-term outcomes for gastric cancer…
- Trial name
- NCT06938139
- Where
- China
- Volunteers
- 90,000 people
- Sponsor
- Fujian Medical University
GIST of Stomach, Gastric Cancer
Comparison of Tumor Efficacy Safety in Laparoscopic Resection of Gastrointestinal Stromal Tumors Between Favorable and Unfavorable Site
Participants with gastrointestinal stromal tumors(GIST) were divided into favorable and unfavorable sites according to the anatomical site of the tumor, and this study aims to validate the overall postoperative morbidity and…
- Conditions
- GIST of Stomach, Gastric Cancer, Surgery, Complication
- Trial name
- NCT03716089
- Testing
- Laparoscopic resection
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Fujian Medical University
Partial Nephrectomy, Renal Hilum Tumors
Analysis of Predictive Factors for Urinary Leakage After Partial Nephrectomy for Renal Hilum Tumors
In this study, we plan to explore the risk factors closely related to the occurrence of urinary leakage after partial nephrectomy for renal hilum tumors through retrospective analysis of multicenter clinical data, thereby…
- Conditions
- Partial Nephrectomy, Renal Hilum Tumors, Urinary Leakage
- Trial name
- NCT06916910
- Where
- China
- Volunteers
- 200 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Prostate Cancer (Post Prostatectomy), Urinary Continence
Analysis of Immediate Urinary Continence Predictors After RS-RARP
This study is a retrospective, single-center clinical trial. It aims to retrospectively analyze the immediate postoperative urinary continence recovery in prostate cancer patients who underwent Retzius-sparing robot-assisted…
- Conditions
- Prostate Cancer (Post Prostatectomy), Urinary Continence, Retzius-sparing Robot-assisted Radical Prostatectomy
- Trial name
- NCT06850116
- Testing
- Retzius-sparing robot-assisted radical prostatectomy
- Where
- China
- Volunteers
- 400 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Advanced Gastric Cancer
Camrelizumab Combined with Apatinib Mesylate Tablets, Nab-paclitaxel and S-1 in the Treatment of Locally Advanced Gastric Cancer
To evaluate the clinical efficacy and safety of camrelizumab combined with apatinib mesylate, nab-paclitaxel and S-1
- Trial name
- NCT04195828
- Testing
- Camrelizumab, Apatinib Mesylate, nab-paclitaxel
- Where
- China
- Volunteers
- 106 people
- Sponsor
- Fujian Medical University
Spontaneous Intracerebral Hemorrhage, Motor Function
Rehabilitation Paired with VNS for Motor Function Recovery
The goal of this clinical trial is to investigate the efficacy and safety of vagus nerve stimulation (VNS) combined with rehabilitation in improving upper extremity motor function after spontaneous intracerebral hemorrhage (ICH).
- Conditions
- Spontaneous Intracerebral Hemorrhage, Motor Function, Upper Extremity Injury, Rehabilitation
- Trial name
- NCT06892574
- Testing
- Active-VNS
- Volunteers
- 10 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University