Clinical trials: open to volunteers, sponsored by Hôpital le Vinatier
Stress (Psychology), Environment
Stress Through Audition: Uptake, Recovery, Oscillations During Nature Exposure
The protocol the investigators propose aims to address certain gaps by developing a multimodal paradigm, based on: Induction of acute stress via the Maastricht Acute Stress Test (MAST), a standardised protocol recognised for its…
- Trial name
- SAURON (NCT07857239)
- Testing
- Natural soundscape auditory exposure, Urban soundscape auditory exposure
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Hallucinations, Auditory
Impact of EDEN College Courses on the Quality of Life of Voice-Hearers
The goal of this Mixed study, combining a randomized controlled trial and an Interpretative Phenomenological Analysis (IPA-qualitative study) is to evaluate the effects of the EDEN College courses on quality of life, compared…
- Trial name
- EDEN-RCT (NCT07694193)
- Testing
- EDEN College, TAU
- Where
- 8 sites in France
- Volunteers
- 240 people
- Sponsor
- Hôpital le Vinatier
Depression Disorder
Estimation of Control Before and After Treatment of a Depressive Episode With Serotonin Reuptake Inhibitors
The goal of this observational study is to better understand cognitive and affective processes involved in depression, in particular how individuals estimate their perception of control over events in their environment, as well…
- Trial name
- APTE-Sero (NCT07716982)
- Testing
- Selective Serotonin Reuptake Inhibitors (SSRIs) or serotonergic antidepressants, Experimental tasks
- Where
- France
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Neurosciences
REALITY MONITORING AND DOPAMINE
Reality-monitoring characterizes the ability to determine whether information was perceived in the environment or only imagined .
- Trial name
- MORDOR (NCT05711082)
- Testing
- Précurseur de la dopamine, antagoniste D2
- Where
- France
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Schizophrenia
Efficiency Assessment of BREFORM. A Multicentric Stepped-wedge Randomized Control Trial.
In psychiatry, caregiver burden is associated with excess physical and psychological morbidity in relatives of patients with schizophrenic disorders Single or multi-family psychoeducation for caregivers of patients with…
- Trial name
- BREFORM (NCT05036590)
- Testing
- control group, Intervention group
- Where
- France
- Volunteers
- 206 people
- Sponsor
- Hôpital le Vinatier
Post Traumatic Stress Disorder
People Bereaved by Violent Death : Negative Event Biases and Temporal Perception
A violent death is defined by its brutality, unexpectedness and is secondary to an external cause (suicide, homicide, accident).
- Trial name
- PrEVENT (NCT05874362)
- Testing
- Diagnosis of depressive episode or post traumatic stress disorder, No diagnosis of depressive episode or post traumatic stress disorder
- Where
- France
- Volunteers
- 61 people
- Sponsor
- Hôpital le Vinatier
Trauma, Psychological
Interaction Between Early Trauma and Odor-induced Dopamine Release
This prospective, double-blind, parallel-group controlled trial aims to investigate the consequence of early trauma on dopamine release evoked by positive valence odors.
- Trial name
- T-ODOR (NCT06284382)
- Testing
- High score at Childhood Trauma Questionnaire., Low score at Childhood Trauma Questionnaire.
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Neurodevelopmental Disorders
Homelessness and Prevalence of Neurodevelopmental Disorders
Introduction \& Central question: Psychiatric disorders are highly prevalent in the homeless population, however neurodevelopmental disorders are also at risk of leading to homelessness (Churchard et al., 2018; Casey et al.…
- Trial name
- PRECA'TND (NCT06869915)
- Testing
- Prevalence (percentage) of ASD, ADHD and IDD in the studied population (homeless people sheltered in accommodation and social rehabilitation centers).
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Hôpital le Vinatier
Mental Disorders
Implementation of REFOCUS Training Program in Mental Health Services
Training of mental health service teams in the orientation of care towards recovery through a 3-day training course: REFOCUS. This training aims to orient care towards recovery.
- Trial name
- RETAFORM (NCT05824234)
- Testing
- Implementation of a training centered around the notions of recovery with mental health services first year, Implementation of a training centered around the notions of recovery with mental health services second year
- Where
- France
- Volunteers
- 760 people
- Sponsor
- Hôpital le Vinatier
Cocaine-Related Disorders
Bright Light Therapy During Inpatient Cocaine Detoxification
Cocaine is a major psychostimulant used to induce a state of euphoria, improved self-confidence and resistance to fatigue, with suppression of sleep.
- Trial name
- COKELUX (NCT07545798)
- Testing
- Medical light therapy device
- Where
- France
- Volunteers
- 256 people
- Sponsor
- Hôpital le Vinatier
Down Syndrome
tDCS for Catatonic Depression in Down Syndrome: A Pilot Study
This study evaluates the efficacy of transcranial direct current stimulation (tDCS) for depression with catatonia in individuals with Down syndrome (DS).
- Trial name
- TOTORO (NCT06866925)
- Testing
- Transcranial stimulation
- Where
- France
- Volunteers
- 62 people
- Sponsor
- Hôpital le Vinatier
Cocaine Use Disorder
Impact of Cocaine Use and Withdrawal on Sleep
This study investigates how cocaine use and withdrawal affect sleep and circadian rhythms in individuals undergoing inpatient detoxification.
- Trial name
- CokeSo (NCT07119567)
- Testing
- Multimodal Sleep and Biomarker Assessment
- Where
- 3 sites in France
- Volunteers
- 32 people
- Sponsor
- Hôpital le Vinatier
Schizophrenia
French Source-monitoring Task
Source-monitoring is a cognitive process that refers to the ability to remember the source of an information. Source-monitoring processes are usually studied using experimental behavioral tasks.
- Trial name
- SOUMO (NCT04237155)
- Testing
- Questionnaire, Cognitive tests
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
First Episode Psychosis (FEP), Caregiver Burden
Psychoeducation Program for Family Caregivers Coordinated by an APRN
The aim of this study is to assess the impact of implementing a specific family program coordinated by APRNs, covering the 5 levels of the family care pyramid through a consultation, an individual psychoeducation program and a…
- Conditions
- First Episode Psychosis (FEP), Caregiver Burden, Nurse Practitioners, IMPACT OF A NEW PSYCHOEDUCATION PROGRAM COORDINATED BY AN ADVANCED PRACTICE NURSE ON THE BURDEN OF FAMILY CAREGIVERS OF PATIENTS WITH A FIRST PSYCHOTIC EPISODE
- Trial name
- APIPEP (NCT07041463)
- Testing
- Psychoeducation program coordinated by an APRN, Usual Care
- Where
- 5 sites in France
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
SCHIZOPHRENIA 1 (Disorder), Sensory Perceptual Characteristics
Precision HD-tACS for Enhancing Sensory Experience in Schizophrenia
To ensure unified sensory perception, the brain must link information from different senses across time and space. This unification of perception often referred to as a perceptual "binding constraint" is a prerequisite for any…
- Trial name
- TherACles (NCT07632261)
- Testing
- Transcranial neurostimulation
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Schizophrenia Spectrum Disorders, Social Cognition
Using Illusions to Boost Social Cognition
This study aims to explore whether the observation of complex visual objects can help improve social cognition in people living with psychotic disorders.
- Trial name
- SOLLUSIONS (NCT07602712)
- Testing
- Visual-illusion social cognition session (immediate), Visual-illusion social cognition session (delayed)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Hôpital le Vinatier
Alcohol Use Disorder (AUD)
Evaluation of a Virtual Reality-based Version of the Multiple Errands Test in Alcohol Use Disorder
The goal of this study is to validate the virtual version of the Multiple Errands Test (V-MET) as a tool for assessing executive functions in patients with alcohol use disorder (AUD). More specifically, the project aims to: 1.
- Trial name
- EVIMETAL (NCT07593664)
- Testing
- Multiple Errand Test (MET), Virtual MET
- Where
- 2 sites in France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Suicide Prevention
Feasibility Study of a Combined Intervention for Suicidal Inpatients in Psychiatric Crisis Units.
Since 2014, suicide prevention has been a national priority and is one of the 3 priority areas of the mental health plan's roadmap . Hospitalization offers a crucial opportunity for life-preserving intervention .
- Trial name
- HOPAIR (NCT07119671)
- Testing
- HOPAIR Intervention: Meeting between Peer Helper and Concerned Individual in Psychiatric Crisis Unit
- Where
- France
- Volunteers
- 42 people
- Sponsor
- Hôpital le Vinatier
Intellectual Developmental Disorder
Emotional Processes in Adults With Intellectual Developmental Disorder
Emotions play a crucial part in the quality of life, interpersonal relationships and mental health in general. In adults presenting with intellectual developmental disorder (IDD), emotional abilities may be hindered, thus leading…
- Trial name
- EmoTDI (NCT07303270)
- Testing
- ACQUISS protocol assessing emotional processing.
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Borderline Personality Disorder BPD
Characterization of the Neural Bases of Mental Imagery in Individuals With Borderline Personality Disorder: An EEG Study
Borderline Personality Disorder (BPD) involves altered social cognition, notably dysfunctional processing of cues signaling potential social exclusion and heightened social pain.
- Trial name
- BABO (NCT07428200)
- Testing
- 2 Tasks : - stop signal reaction time and Cyberball then ill out an evaluation form
- Where
- France
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier