Clinical trials: sponsored by Henry Ford Health System
Surgical Site Infection, Groin Infections
Negative Pressure Wound Therapy for Surgical Site Infection Prevention in Common Femoral Artery Exposure
The purpose of this randomized clinical trial is to investigate the role of negative pressure wound therapy (NPWT) vs standard sterile gauze therapy on the incidence of surgical site infections (SSI) in primarily closed groin…
- Trial name
- NCT03935659
- Testing
- Negative Pressure Pressure Wound Therapy, Standard Wound Care
- Where
- United States
- Sponsor
- Henry Ford Health System
HIV Infections
B/F/TAF Ease of Swallowability Trial
The trial will assess the tolerability and swallowability of a STR placebo of B/F/TAF as compared to DTG/ABC/3TC placebo STR in healthy individuals and HIV antiretroviral naïve patients.
- Trial name
- BEST (NCT04600687)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Diabetes Mellitus, Type 2
The Fruit and Vegetable Prescription Program Study
The Fruit and Vegetable Prescription Program Study is a pilot randomized controlled trial of patients with type 2 diabetes participating in a fruit and vegetable prescription program from a Federally Qualified Health Center in…
- Trial name
- NCT04597957
- Testing
- Fresh Rx Intervention group
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Henry Ford Health System
Chronic Knee Pain
Cooled Versus Conventional Genicular Radiofrequency Ablation for Chronic Knee Pain
This prospective observational study seeks to compare pain relief and disability following cooled radiofrequency ablation (Coolief) versus conventional genicular nerve ablation in patients with chronic knee pain.
- Trial name
- NCT04275128
- Testing
- Cooled radiofrequency ablation, Conventional radiofrequency ablation
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Henry Ford Health System
Obesity, Overweight
Pediatric Preventative Health Screenings - Obesity and Family-Centered Outcomes
In 2012, an Expert Panel of the National Heart Lung and Blood Institute published guidelines on cardiovascular health and risk reduction in children; among these guidelines were screening recommendations for obesity and…
- Conditions
- Obesity, Overweight, Blood Pressure, Hypercholesteremia
- Trial name
- NCT02850224
- Testing
- Motivational interviewing to elicit PCO in pediatrics
- Where
- United States
- Volunteers
- 703 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
COVID, Pneumonia, Viral
Early Short Course Corticosteroids in COVID-19
The investigators intend to study the role of early use of methylprednisolone in the hospitalized patients with a diagnosis of COVID-19 pneumonia.
- Trial name
- NCT04374071
- Testing
- Methylprednisolone
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Henry Ford Health System
Post Operative Nausea and Vomiting
Effects of Preoperative Carbohydrate Rich Drinks on Immediate Postoperative Outcome in Total Knee Arthroplasty
The aim of this study is to investigate the effect of preoperative carbohydrate rich drinks on postoperative nausea and vomiting in total knee arthroplasty. This is a prospective, double blinded, randomized controlled trial.
- Trial name
- PONV (NCT03380754)
- Testing
- Nutricia preOp
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Coronary Artery Disease
Pilot Evaluation of the JHI Platform
The main purpose of this pilot study is to evaluate an impact of JHI CR Platform on patient referral, recruitment and retention rates and overall patient satisfaction in cardiovascular rehabilitation programs at the HFHS.
- Trial name
- NCT01648673
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Henry Ford Health System
Insomnia, Post Partum Depression
Insomnia and Rumination in Late Pregnancy and the Risk for Postpartum Depression
The primary objective of the proposed research is to determine whether prenatal insomnia and ruminative thinking predict severity of postpartum depression (PPD) symptoms.
- Trial name
- PPD (NCT03596879)
- Testing
- dCBTI, Sleep Education
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- Henry Ford Health System
Insomnia
Study to Compare the Awakening Threshold Effects of Belsomra 10 mg and 20 mg to Placebo in Non-elderly Insomniacs
Phase IV 3-Way Double-blind, Randomized, Crossover Study to Compare the Awakening Threshold Effects (responsivity) of Belsomra 10 mg and 20 mg to Placebo in non-elderly Insomniacs
- Trial name
- NCT03312517
- Testing
- Suvorexant 10 mg, Suvorexant 20 mg
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Henry Ford Health System
Ulcers, Bedsores
Utility of Interface Pressure Mapping
To determine if a device that measures and displays pressure that the patients feel when in bed can help nurses reposition the patient effectively and thereby reduce bedsores in the intensive care unit.
- Trial name
- NCT01439581
- Testing
- Mapping System, Non-Mapping System
- Where
- United States
- Volunteers
- 428 people
- Sponsor
- Henry Ford Health System
Achilles Tendon Rupture
Achilles Tendon Lengthening With Traditional vs. Accelerated Rehab
The purpose of this study is to evaluate the surgically repaired tendon of a ruptured achilles tendon. We will investigate fixation slippage and tendon creep and correlate how these post-repair findings can contribute to outcomes…
- Trial name
- NCT04050748
- Testing
- Achilles tendon repair
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Carpal Tunnel Syndrome
Carpal Tunnel Release Effects on Median Nerve Perfusion
This study aims to examine the effect of carpal tunnel release on blood flow to the median nerve using SPY scope imaging to view the perfusion to the nerve.
- Trial name
- NCT01610739
- Testing
- Indigocyanine green dye
- Where
- United States
- Sponsor
- Henry Ford Health System
Asthma
Study of Asthma Phenotypes and Pharmacogenomic Interactions by Race-Ethnicity (SAPPHIRE)
Inhaled corticosteroids (ICS) are considered first-line treatment for persistent asthma, yet little is known about the genetic factors that influence response to this therapy.
- Trial name
- SAPPHIRE (NCT01142947)
- Testing
- beclomethasone dipropionate
- Where
- United States
- Volunteers
- 362 people
- Sponsor
- Henry Ford Health System
Osteoporosis, Atypical Femoral Fractures
Pathogenesis of Atypical Femur Fractures on Long Term Bisphosphonate Therapy
The purpose of this protocol is to determine the risk of atypical femoral shaft (thigh bone) fractures after long term fracture prevention therapy with a class of drugs called "bisphosphonates", colloquially referred to as…
- Conditions
- Osteoporosis, Atypical Femoral Fractures, Prodromal Bone Deterioration
- Trial name
- NIH fracture (NCT02155595)
- Testing
- 500 without BP treatment, 500 with BP treatment
- Where
- United States
- Volunteers
- 738 people
- Sponsor
- Henry Ford Health System
Hypertension
Enhancing Systems of Care to Improve Hypertension Guideline Implementation
This study is a prospective cluster randomized trial testing a systems-level strategy to implement current American Heart Association hypertension guidelines in African American communities at risk for cardiovascular related…
- Trial name
- NCT03563872
- Testing
- Intervention, Active Comparator
- Where
- United States
- Sponsor
- Henry Ford Health System
Narcotic Use
Nonopioid Analgesia After Labral Surgery
This is a randomized, single blinded, standard of care controlled clinical trial. This project aims to compare postoperative pain control in patients in two treatment arms of rotator cuff repair: a treatment group given a…
- Trial name
- NCT03825809
- Testing
- Celecoxib, Hydrocodone-Acetaminophen, Ketorolac
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Doxorubicin Induced Cardiomyopathy, Breast Cancer
Prevention Using Exercise Rehabilitation to Offset Cardiac Toxicities Induced Via Chemotherapy
The purpose of this study is to identify patients at risk for future heart failure using novel markers of early cardiac damage and determine if exercise training can improve these emerging markers as well as overall fitness and…
- Conditions
- Doxorubicin Induced Cardiomyopathy, Breast Cancer, Gastric Cancer, Leukemia
- Trial name
- HF-PROACTIVE (NCT02796365)
- Testing
- Exercise
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Henry Ford Health System
Asthma, Obesity
Teen Asthma Control Encouraging a Healthier Lifestyle
Little guidance is given to physicians caring for obese adolescents with asthma, however, findings suggest that interventions designed to achieve asthma control in these patients are necessary.
- Trial name
- TAC (NCT02575326)
- Testing
- Standard Control, a provider administered, tailored discussion guide
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Asthma
Web-Based and Tailored Asthma Management Intervention (Puff City) in Teens With Asthma Attending Urban Clinics
The purpose of this study is to evaluate the Puff City web-based behavioral intervention of asthma management program in a clinical setting.
- Trial name
- PCC (NCT01757002)
- Testing
- Teens randomized to the experimental arm will receive 4 sessions plus a booster of web-based, tailored asthma management., Teens in the control group will receive generic, web-based asthma education.
- Where
- United States
- Volunteers
- 266 people
- Sponsor
- Henry Ford Health System