Clinical trials: sponsored by Henry Ford Health System
Pancreas Neoplasm Malignant Resectable
Phase II Study of Chemo-Radiotherapy in Patients With Resectable and Borderline Resectable Pancreatic Cancer
To evaluate the safety and effectiveness of a novel neoadjuvant treatment strategy incorporating 5-fluorouracil/leucovorin with oxaliplatin ( FOLFOX )chemotherapy in combination with chemo-radiation with gemcitabine.
- Trial name
- NCT02243358
- Testing
- Folfox6, Gemcitabine, Radiation Therapy
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Henry Ford Health System
GVHD
Immuno-regulatory Profiling of T Cells in GVHD Treated With Extracorporeal Photopheresis
Extracorporeal Photopheresis (ECP) has been used as one of the treatments for graft versus host disease (GVHD). Responses were observed in skin, liver, GI tract, mouth, eye and lung.
- Trial name
- NCT03851601
- Testing
- blood samples
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Henry Ford Health System
Abdominal Pain, Surgical Adhesions
Pregabalin for Abdominal Pain From Adhesions
The purpose of this study is to evaluate if pregabalin demonstrates significant reduction in abdominal pain from adhesions.
- Trial name
- NCT00310765
- Testing
- Pregabalin 75 or 150 mg BID for 7 weeks followed by open label pregabalin 150 mg BID for 4 weeks
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Henry Ford Health System
Prostate Cancer
Multi-parametric Magnetic Resonance Imaging for Prostate Cancer Patients
This is a pilot study of implement multi-parametric MR imaging for organ delineation and tumor response assessment of prostate cancer patients being treated with radiation therapy.
- Trial name
- NCT03180398
- Testing
- Multiparametric MRI
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Arthritis of Hip
Fascia Iliaca Blocks for Pain Control After Total Hip Arthroplasty
The fascia iliaca compartment block (FICB) is a regional block that anesthetizes the femoral, obturator, and lateral femoral cutaneous nerves around the hip.
- Trial name
- NCT03375112
- Testing
- Fascia iliaca compartment block, Bupivacaine
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- Henry Ford Health System
Post Operative Pain
Dexamethasone Administered Via the Epidural Catheter as an Adjunct in Patients Undergoing Cesarean Delivery
This study will evaluate the ability of dexamethasone to enhance labor epidurals when administered as an adjunct to local anesthetics via an epidural catheter.
- Trial name
- NCT03877549
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Labor Pain, Analgesia
Effect of Epidural Analgesia During Labor on Force of Maternal Push
There are multiple factors that determine progress of normal vaginal delivery. Frequency, duration and strength of uterine contractions are important for progress throughout labor, and abdominal wall muscle contractions…
- Conditions
- Labor Pain, Analgesia, Maternal; Procedure
- Trial name
- NCT04888858
- Testing
- Epidural analgesia (0.125% bupivacaine/2mcg fentanyl solution)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Heart Failure With Reduced Ejection Fraction, Left Ventricular Assist Device
Influence of Right Ventricular Function on Changes in Exercise Capacity After LVAD
This is an exploratory project with the purpose to describe the responses of the right ventricle (RV) and gas exchange during exercise in patients scheduled to undergo left ventricular assist device (LVAD) implant.
- Trial name
- NCT05916612
- Sponsor
- Henry Ford Health System
Intraoperative Monitoring
Comparison of Intraoperative HR and RR Acquired Via ATLASense Raphael PolyMonitor and Standard Intraoperative Monitors
The aim of this observational comparison study is to compare the HR and respiratory RR of intraoperative surgical patients simultaneously recorded by standard intraoperative monitors and the ATLASense RAPHAEL PolyMonitor.
- Trial name
- ATLASense (NCT05291949)
- Testing
- ATLASense RAPHAEL PolyMonitor
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Henry Ford Health System
Quality of Life, Brain Tumor
Quality of Life and Patient Needs in Advanced High Grade Gliomas
There is limited knowledge regarding the quality of life and needs of patients with advanced high grade gliomas, especially during the end of life.
- Conditions
- Quality of Life, Brain Tumor, Glioblastoma, Glioma
- Trial name
- NCT05039346
- Testing
- Phone interviews
- Volunteers
- 55 people
- Sponsor
- Henry Ford Health System
Healthy
Innovative Strategies Which Improve the Clinical Handoff (I-SWITCH)
Study the feasibility of different educational modalities to improve resident handoff of patient information b) Determine whether different educational modalities (powerpoint vs.
- Trial name
- I-SWITCH (NCT00917072)
- Testing
- Didactic, Didactic+Simulation, Control
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Recurrent or Progressive Glioblastoma
Stereotactic Radiology Versus Chemotherapy for Recurrent/Progressive Glioblastoma After Second-Line Chemotherapy
This clinical trial is a prospective study of radiosurgery treatment for progressive GBM to test 1)the efficacy of radiosurgery for recurrent/progressive GBM compared to chemotherapy , and 2) the role of diffusion-weighted image…
- Trial name
- NCT05718466
- Testing
- Bevacizumab, Chemotherapy, Fractionated radiosurgery
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Henry Ford Health System
Right Bundle-Branch Block
Adaptive Cardiac Resynchronization Therapy in Patients With RBBB
This study will address whether acute adaptive RV pacing in sinus rhythm patients with severe LV systolic dysfunction and RBBB is superior to no ventricular pacing, and is as effective as echocardiographically optimized…
- Trial name
- NCT05936294
- Testing
- Optimization of CRT Device
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- Henry Ford Health System
Colonoscopy
Amitiza® Plus GoLYTELY® (PEG) Versus Placebo Plus GoLYTELY® for Outpatient Colonoscopy Preparation
The primary objective is to compare the effectiveness and tolerance of the medication named lubiprostone plus a large volume liquid laxative versus placebo which is a look alike medication that has no effect such as a sugar pill…
- Trial name
- PEG (NCT00645801)
- Testing
- lubiprostone (Amitiza)
- Where
- 3 sites in United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Acute Asthma
A Pilot Study to Determine the Most Effective Dose of Arformoterol for Treating Acute Asthmatic Patients
The purpose of this study is to determine the best dose of nebulized arformoterol, a quick onset but long acting beta agonist, for use in treating acute bronchospasm in asthmatics presenting to the the Emergency Department.
- Trial name
- NCT00819637
- Testing
- arformoterol (RR formoterol), levalbuterol
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Henry Ford Health System
Cervical Ripening
Cervical Ripening With Cook Catheter Plus Low Dose Oxytocin
The purpose of this study is to compare if using a Cook Cervical Ripening Balloon in conjunction with low dose oxytocin is more effective at shortening labor induction times than the Cook Cervical Ripening Balloon alone.
- Trial name
- NCT02465164
- Testing
- Cook catheter, Oxytocin
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Health Care Associated Pneumonia, Osteomyelitis/Septic Arthritis
Safety and Efficacy of Strategy to Prevent Drug-Induced Nephrotoxicity in High-Risk Patients
For more than fifty years, vancomycin has been cited as a nephrotoxic agent. Reports of vancomycin induced kidney injury (a.k.a vancomycin induced nephrotoxicity or VIN), have waxed and waned throughout the years for various…
- Conditions
- Health Care Associated Pneumonia, Osteomyelitis/Septic Arthritis, Endocarditis, Bacteremia
- Trial name
- STOP-NT (NCT01734694)
- Testing
- Vancomycin, Ceftaroline, Daptomycin
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Henry Ford Health System
Acute Blood Loss Anemia, Osteoarthritis, Knee
Topical Tranexamic Acid and Acute Blood Loss in Total Knee Arthroplasty
This study aims to assess postoperative blood loss and transfusion rates in total knee replacement after one-time administration of topical tranexamic acid.
- Trial name
- NCT01370460
- Testing
- Tranexamic Acid
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Henry Ford Health System
Thoracolumbar Spinal Fusions
Ketorolac on Posterior Thoracolumbar Spinal Fusions
To determine is low-dose ketorolac use in the early post-operative period (within 48 hours) provides adequate analgesia without long term adverse effect on spinal fusion rates when compared to post-operative analgesia without the…
- Trial name
- NCT03278691
- Testing
- Saline, Ketorolac
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Vestibular Schwannoma, Cochlear Implantation
Simultaneous Cochlear Implantation During Translabyrinthine Resection of Vestibular Schwannoma
This study will address the feasibility of simultaneous cochlear implantation during resection of a vestibular schwannoma.
- Trial name
- NCT03958006
- Testing
- Cochlear implant
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Henry Ford Health System