Clinical trials: sponsored by Hospital for Special Surgery, New York
CRPS (Complex Regional Pain Syndromes)
Forward Looking InfraRed Imaging and Severity Score in Complex Regional Pain Syndrome
The goal of this interventional study is to explore the use of InfraRed (FLIR) imaging in determining pain intensity and severity in newly diagnosed complex regional pain syndrome patients.
- Trial name
- FLIR (NCT05852210)
- Testing
- Infrared Imaging
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Hospital for Special Surgery, New York
Total Knee Replacement, Post-operative Nausea and Vomiting
Aromatherapy in Total Knee Replacement
The purpose of this pilot randomized controlled trial is to investigate the effects of aromatherapy on postoperative anxiety and pain in total knee replacement patients.
- Conditions
- Total Knee Replacement, Post-operative Nausea and Vomiting, Opioid Use, Anxiety
- Trial name
- NCT06045078
- Testing
- Elequil Lavender-peppermint Aromatabs, Elequil Almond-Oil Aromatabs
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Hospital for Special Surgery, New York
Pain, Postoperative, Opioid Use
Cannabidiol for Bilateral Total Knee Arthroplasty
In light of the opioid epidemic and evidence suggesting that cannabis may be opioid-sparing, we are in a unique position to conduct a novel, high-impact study that would set the stage for future RCTs examining the effects of a…
- Conditions
- Pain, Postoperative, Opioid Use, Knee Osteoarthritis
- Trial name
- NCT04749628
- Testing
- cannabidiol, Ora-sweet SF
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Hospital for Special Surgery, New York
Total Knee Arthroplasty, Opioid Use
Dronabinol in Total Knee Arthroplasty (TKA)
The goal of this double-blinded randomized controlled trial is to compare whether the addition of Dronabinol compared to a placebo will affect opioid intake in patients undergoing a total knee arthroplasty.
- Trial name
- NCT04734080
- Testing
- Dronabinol 5mg Cap
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Hospital for Special Surgery, New York
ACL, Anterior Cruciate Ligament Injuries
Genicular Nerve Blocks for Anterior Cruciate Ligament Knee Surgery
The purpose of this randomized controlled trial is to assess a new analgesia regimen that includes the addition of genicular never blocks to our current standard regimen of peripheral nerve blocks, which includes an adductor…
- Trial name
- NCT05720949
- Testing
- Genicular Nerve Block with bupivacaine and preservative free dexamethasone
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Hospital for Special Surgery, New York
Ankle Surgery, Foot Surgery
MIDCAB (Mid-Calf Block) for Foot Surgery
MIDCAB is defined as a group of ultrasound guided distal nerve blocks at the level of the individual branches. It is similar to an Ultrasound Guided (USG) Ankle block but the probe is placed higher on the calf covering all and…
- Trial name
- MIDCAB (NCT05368012)
- Testing
- MIDCAB
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Hospital for Special Surgery, New York
TSA, Bruise
Natural History of Pain After Shoulder Arthroplasty Conducted With Multimodal Analgesia
This study aims to identify the timeline of pain following total shoulder replacement with the goal of developing data for a subsequent randomized trial.
- Conditions
- TSA, Bruise, Pain, Postoperative
- Trial name
- TSA (NCT03021096)
- Testing
- Surveys
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Fractures, Bone, Deformity; Bone
Virtual Reality Distraction During Outpatient Pediatric Orthopedic Procedures
Virtual Reality(VR) has had promising applications in science and medicine, including intervention delivery. The use of VR interventions has been studied in a wide range of medical conditions, including anxiety, phobias, obesity…
- Trial name
- NCT05510232
- Testing
- A treatment group that will watch a non-VR video via an iPad, A treatment group that will have headset on and will watch a non-VR video, A treatment group that will be immersed in the VR game (Bear Blast) via the headset.
- Where
- United States
- Volunteers
- 226 people
- Sponsor
- Hospital for Special Surgery, New York
Joint Disease, Pain, Acute
Effect of Duloxetine on Opioid Use After Total Knee Arthroplasty
Post-discharge pain after total knee arthroplasty remains problematic; many patients have excessive pain at the 2 week time point (and often thereafter).
- Conditions
- Joint Disease, Pain, Acute, Pain, Chronic
- Trial name
- NCT03271151
- Testing
- Cymbalta
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Hospital for Special Surgery, New York
ACL, ACL Injury
Acupuncture ACL (Anterior Cruciate Ligament)
Acupuncture research in regards to PONV has been fairly well established, however, studies about perioperative pain control and acupuncture are a little more murky.
- Conditions
- ACL, ACL Injury, Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
- Trial name
- NCT03711734
- Testing
- Acupuncture + Standard of Care
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Pain, Joint Stiffness
Persistent Postoperative Pain and Joint Stiffness After Total Knee Arthroplasty Performed for Osteoarthritis
Persistent pain and joint stiffness after surgery may interfere with recovery and adversely affect quality of life in up to 40% of patients who have undergone total knee arthroplasty.
- Trial name
- NCT02626533
- Testing
- Total Knee Arthroplasty
- Where
- United States
- Volunteers
- 179 people
- Sponsor
- Hospital for Special Surgery, New York
Stress, Psychological
Audiovisual Aid Pilot Study
Little is known about perioperative stress responses and possible anxiety mitigating factors like audiovisual aids or IV sedation.
- Trial name
- NCT02506673
- Testing
- Zeiss, Cinema ProMED (audiovisual equipment), Midazolam, Skin Conductance Monitor
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Hospital for Special Surgery, New York
Blood Loss, Blood Transfusion
Oral Versus Intravenous Tranexamic Acid
The goal of this randomized clinical control trial is to determine whether oral TXA dosing in THA/TKA result in more blood loss and more transfusions compared to IV TXA dosing in patients undergoing THA/TKA under neuraxial…
- Trial name
- NCT04089865
- Testing
- Tranexamic Acid
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Shoulder Pain
Rotator Cuff Pathway
Rotator cuff surgery is mostly performed on an outpatient basis, and many patients still experience moderate to severe pain after surgery, despite the use of regional anesthesia and opioids.
- Trial name
- NCT03717753
- Testing
- Pathway
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Hospital for Special Surgery, New York
Total Hip Arthroplasty, Primary Total Hip Arthroplasty
Outcomes After Hypotensive Neuraxial Anesthesia in Total Hip Arthroplasty
This is a retrospective chart review to determine if neuraxial anesthesia is associated with worse outcomes after Primary Total Hip Arthroplasty.
- Conditions
- Total Hip Arthroplasty, Primary Total Hip Arthroplasty, Hypotension, Database
- Trial name
- NCT03973320
- Testing
- Chart Review
- Where
- United States
- Volunteers
- 11,292 people
- Sponsor
- Hospital for Special Surgery, New York
Osteoarthritis, Hip
Minimal Opioid Use After Total Hip Replacement (THR)
Total hip arthroplasty can be associated with significant postoperative pain. Side effects of pain management may impair participation in physical therapy and slow readiness for discharge from the hospital.
- Trial name
- NCT03090152
- Testing
- Periarticular injection (Deep injection), Periarticular injection (Superficial injection), Bupivacaine
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Hospital for Special Surgery, New York
Knee Osteoarthritis, Pain, Postoperative
Acupuncture for Low-Dose Opioid for TKA Replacement
The majority of patients undergoing total knee replacement(TKR) rely on opioids for postoperative analgesia. These medications have undesirable side effects and potential for abuse and addiction.
- Conditions
- Knee Osteoarthritis, Pain, Postoperative, Acupuncture
- Trial name
- NCT04084288
- Testing
- Acupuncture, Peripheral Nerve Stimulator
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Hospital for Special Surgery, New York
Pain, Postoperative, Opioid Use
Erector Spinae Plane Blocks for Adolescent Idiopathic Scoliosis
Pediatric spinal fusion (PSF) surgery is a painful procedure that can treat adolescent idiopathic scoliosis (AIS). One technique that can potentially reduce patients' pain levels and need for opioid medication is the…
- Conditions
- Pain, Postoperative, Opioid Use, Recruitment
- Trial name
- NCT04500613
- Testing
- Bilateral Erector Spinae Plane Block with bupivacaine and dexamethasone, No bilateral Erector Spinae Plane Block (no bupivacaine and no dexamethasone)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Hospital for Special Surgery, New York
Total Knee Athroplasty
Does PAI Reduce Pain After TKA Among Knee Arthroplasty Patients Receiving ACB & IPACK?
The goal of this clinical trial is to determine whether Periarticular Injection (PAI) alongside Adductor Canal Block (ACB) and Infiltration between the Popliteal Artery and Capsule of the Knee (IPACK) block can decrease…
- Trial name
- NCT04749615
- Testing
- Periarticular Injection (PAI), Saline Control Periarticular Injection (PAI)
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Hospital for Special Surgery, New York
Cerebral Oxygen Desaturation, Post-operative Delirium
Cerebral Oxygenation in Total Hip Arthroplasty Patients
We plan to investigate the relationship between hypotensive epidural anesthesia for hip arthroplasty and cerebral oxygen saturation.
- Trial name
- THANIRS (NCT02325154)
- Testing
- Cerebral Oximeter
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York