Clinical trials: sponsored by Istanbul University - Cerrahpasa
Heart Failure, Breathing Exercises
Breathing Exercises for Dyspnea and Anxiety in Heart Failure
Heart failure is a leading cause of emergency department admissions, with dyspnea and psychological distress being among the most common presenting symptoms.
- Conditions
- Heart Failure, Breathing Exercises, Dyspnea, Anxiety
- Trial name
- NCT07752706
- Testing
- Diaphragmatic and Pursed-Lip Breathing Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people
- Sponsor
- Istanbul University - Cerrahpasa
Newborn Pain, Newborn Stress
Effect of Nesting During Intramuscular Injection on Pain, Stress, and Breastfeeding Success in Cesarean-Born Term Newborns
This randomized controlled trial aims to evaluate the effect of nesting during the first intramuscular injection on pain, stress level, physiological parameters, settling time, and breastfeeding success in healthy term newborns…
- Conditions
- Newborn Pain, Newborn Stress, Breastfeeding Success in Newborns
- Trial name
- NESTING (NCT07748520)
- Testing
- Nesting
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Major Depression Moderate, Major Depression Severe
EEG Microstate Parameters and Neuroinflammatory Biomarkers in Patients With Treatment-Resistant Major Depressive Disorder Receiving ECT
This study aims to investigate the neurophysiological and inflammatory changes associated with electroconvulsive therapy (ECT) in patients diagnosed with Major Depressive Disorder who are resistant to at least two antidepressant…
- Conditions
- Major Depression Moderate, Major Depression Severe, Major Depression With Comorbid Anxiety Symptoms, Major Depression With Panic Attacks
- Trial name
- NCT07748091
- Testing
- Electroconvulsive Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Childhood Obesity, Aerobic Exercise
Effects of Progressive Neuromuscular Stabilization Exercises Versus Aerobic Exercises on Body Composition and Postural Balance in Children With Obesity
Introduction: Childhood obesity can impair postural control, balance, and motor skills, thereby limiting participation in physical activity.
- Conditions
- Childhood Obesity, Aerobic Exercise, Exercise
- Trial name
- NCT07744022
- Testing
- Progressive Neuromuscular Stabilization Exercise, Aerobic Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Istanbul University - Cerrahpasa
Rotator Cuff Injuries, Shoulder Pain Chronic
The Relationship Pain Beliefs With Kinesiophobia, Catastrophizing, Pain Knowledge, and Shoulder Functional Disability in Individuals With Shoulder Pain
This cross-sectional observational study aims to examine the relationship between psychological and organic pain beliefs and kinesiophobia, pain catastrophizing, pain knowledge, and shoulder functional disability (SPADI) in…
- Conditions
- Rotator Cuff Injuries, Shoulder Pain Chronic, Impingement Syndrome
- Trial name
- NCT07118163
- Testing
- Other, No intervention; Observational study
- Where
- Turkey (Türkiye)
- Volunteers
- 109 people
- Sponsor
- Istanbul University - Cerrahpasa
Video-assisted Thoracoscopic Surgery (VATS), Thoracic Surgery, Video Assisted
Target-Controlled Infusion (TCI) vs Inhalational Anesthesia in Video-Assisted Thoracoscopic Surgery (VATS)
This study is designed as a prospective observational cohort to evaluate recovery after video-assisted thoracoscopic surgery (VATS).
- Conditions
- Video-assisted Thoracoscopic Surgery (VATS), Thoracic Surgery, Video Assisted, Postoperative Recovery, General Anesthesia
- Trial name
- TCI-INHALE (NCT07288099)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Istanbul University - Cerrahpasa
Major Depression Moderate, Major Depression Severe
EEG Microstate and Neuroinflammatory Biomarkers in Older Age Patients With Major Depressive Disorder Receiving ECT
This study aims to investigate the neurophysiological and inflammatory changes associated with electroconvulsive therapy (ECT) in older age patients diagnosed with Major Depressive Episode, Major Depression, and Bipolar Disorder…
- Conditions
- Major Depression Moderate, Major Depression Severe, Major Depression With Comorbid Anxiety Symptoms, Major Depression With Panic Attacks
- Trial name
- NCT07740694
- Testing
- Electroconvulsive Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Frozen Shoulder, Adhesive Capsulitis
Effect of Hormone Replacement Therapy on Physiotherapy Outcomes in Postmenopausal Women With Frozen Shoulder
The purpose of this study is to compare the effects of a physiotherapy program on pain levels, shoulder range of motion, functional status, pain catastrophizing, perceived change, sleep quality, and quality of life in…
- Conditions
- Frozen Shoulder, Adhesive Capsulitis, Adhesive Capsulitis of the Shoulder, Hormone Replacement Therapy, Post-Menopausal
- Trial name
- NCT07736027
- Testing
- Standardized Physiotherapy Program
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Istanbul University - Cerrahpasa
Heart Failure
Investigation of the Effect of Inspiratory Muscle Training and Dual-Task Inspiratory Muscle Training on Cognitive Functions in Heart Failure
The goal of this clinical trial is to evaluate whether dual-task inspiratory muscle training (IMT) is effective in improving cognitive and functional outcomes in adults with heart failure.
- Trial name
- NCT07581587
- Testing
- Dual-Task IMT, IMT
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Istanbul University - Cerrahpasa
Post-activation Performance Enhancement and Repeated Sprint Performance in Trained Soccer Players
Effects of Heavy Back-Squat PAPE on Jump and Repeated Sprint Performance in Trained Soccer Players
This study examined whether performing heavy back squats before exercise affects jumping ability and repeated sprint performance in trained soccer players.
- Trial name
- NCT07736209
- Testing
- Heavy Back-Squat PAPE Protocol, Standardized Warm-Up Control Condition
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Breech Birth Maneuvers, Virtual Reality (VR) Technology
Virtual Reality Technology-Based Breech Birth Maneuver Training
Midwifery education is a comprehensive process aimed at equipping students with advanced theoretical knowledge, clinical decision-making abilities, and complex psychomotor skills necessary to promote and protect maternal and…
- Trial name
- NCT07732998
- Testing
- Virtual Reality, Conventional Slide-Based Training
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University - Cerrahpasa
Trigger Finger
Betamethasone vs Dextrose Injections in Trigger Finger
This study aims to compare the effectiveness of ultrasound-guided betamethasone and dextrose injections in patients with trigger finger.
- Trial name
- NCT07681804
- Testing
- Betamethasone, Dextrose Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Istanbul University - Cerrahpasa
Stroke, Hemiplegia
Task-Oriented Training Versus High-Intensity Gait Training in People With Chronic Stroke
The purpose of this study is to compare the effects of high-repetition task-oriented training and high-intensity gait training on walking capacity and functional mobility in individuals with chronic stroke.
- Conditions
- Stroke, Hemiplegia, Chronic Stroke
- Trial name
- NCT07725211
- Testing
- Neurodevelopmental Treatment, High-Repetition Task-Oriented Training, High-Intensity Gait Training
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Istanbul University - Cerrahpasa
Cerebral Palsy (CP), Spastic Diplegia Cerebral Palsy
Comparison of Synchronous and Asynchronous Action Observation Therapy in Children With Cerebral Palsy
The aim of this study is to compare the effects of synchronous and asynchronous action observation therapy (AOT) on balance, gait, and functional capacity in children with cerebral palsy (CP).
- Conditions
- Cerebral Palsy (CP), Spastic Diplegia Cerebral Palsy, Spastic Hemiplegic Cerebral Palsy, Neurodevelopmental Disorder (Diagnosis)
- Trial name
- NCT07114731
- Testing
- Synchronous Action Observation Therapy, Asynchronous Action Observation Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Istanbul University - Cerrahpasa
Pediatric Regional Anesthesia, Retrolaminar Block
Retrolaminar Plane Block Versus Anterior Quadratus Lumborum Block in Pediatric Urogenital Surgery
Effective control of postoperative pain following pediatric lower urogenital surgery is important for enhancing recovery and reducing opioid requirements.
- Conditions
- Pediatric Regional Anesthesia, Retrolaminar Block, Pediatric Postoperative Pain
- Trial name
- NCT07711496
- Testing
- Anterior Quadratus Lumborum Block, Retrolaminar Block
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Istanbul University - Cerrahpasa
Adhesive Capsulitis, Corticosteroid Injection
Pericapsular vs Intra-Articular Injection in Adhesive Capsulitis
Adhesive capsulitis is a common and disabling shoulder disorder characterized by progressive pain and restricted active and passive range of motion, leading to significant limitations in daily activities and reduced quality of…
- Trial name
- NCT07710651
- Testing
- Betamethasone
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Istanbul University - Cerrahpasa
Muscle Hypotrophy, Exercise Performance
Resistance Training Adaptations and Caffeine Intake
This parallel-group, randomized, double-blind, placebo-controlled trial investigates the effects of three different caffeine supplementation strategies on resistance training-induced adaptations in 120 caffeine-naive, inactive…
- Conditions
- Muscle Hypotrophy, Exercise Performance, Muscle Strength, Adaptation
- Trial name
- NCT07410195
- Testing
- Caffeine (Constant Daily Dose), Caffeine (Escalating Dose), Caffeine (Training Days Only)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Menopause, Hot Flashes
Effect of Cold Shower Therapy on Hot Flashes And Night Sweats in Menopausal Women
This randomized controlled trial aims to evaluate the effect of a 6-week cold shower therapy on hot flashes and night sweats in menopausal women.
- Conditions
- Menopause, Hot Flashes, Night Sweats
- Trial name
- NCT07695051
- Testing
- Cold Shower Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University - Cerrahpasa
Critical Illness, Frailty
CALLY Index, Frailty and SOFA-2 for Mortality Prediction in Geriatric ICU Patients
This study aims to evaluate the prognostic value of the C-reactive protein-albumin-lymphocyte (CALLY) index, Clinical Frailty Scale (CFS), and SOFA-2 score in predicting mortality among geriatric intensive care unit (ICU)…
- Conditions
- Critical Illness, Frailty, Intensive Care Unit (ICU)
- Trial name
- CALLY-FS (NCT07579728)
- Testing
- observational study
- Where
- Turkey (Türkiye)
- Volunteers
- 138 people
- Sponsor
- Istanbul University - Cerrahpasa
Upper Extremity Fractures, Postoperative Anxiety
The Effect of the Cold Arm Sling Elevation Pillow on Postoperative Anxiety and Comfort in Children
The purpose of this clinical trial is to learn whether the use of a "cold and arm sling elevation pillow" affects anxiety and comfort levels in children aged 7-12 years undergoing surgery for upper extremity fractures.
- Conditions
- Upper Extremity Fractures, Postoperative Anxiety, Patient Comfort
- Trial name
- NCT07475975
- Testing
- Cold and arm sling elevation pillow, Standard postoperative care
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Istanbul University - Cerrahpasa