Clinical trials: sponsored by Laval University
Circulating Tumor Cell, Lung Cancer
Sequence of Vessel Interruption and Circulating Tumor Cells in Surgical Lung Cancer
This study aims to define the impact of the sequence of vessel interruption on change in CTC and CTC clusters density in the tumor-draining pulmonary vein between the period before surgical manipulation and before tumor-draining…
- Conditions
- Circulating Tumor Cell, Lung Cancer, Surgery
- Trial name
- CTC-01 (NCT03645252)
- Testing
- Vein interruption before any other surgical manipulation, Arteries interruption before vein interruption
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Laval University
Chronic Disease
Optimizing Patient Usability Experience for Chronic Care
The study aims to develop a module of an eHealth platform, do a feasibility study through a pilot cluster randomized control trial and assess the scalability of the solution.
- Trial name
- NCT03628963
- Testing
- Concerto+
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Laval University
Shoulder Impingement Syndrome, Shoulder Rotator Cuff Tendinopathy
Effectiveness of Supervised Motor Control Exercises on Rotator Cuff Tendinopathies
The shoulder is the most mobile joint in the body but still has the responsibility of ensuring a strong stability of our upper limbs during daily activities.
- Trial name
- NCT02926443
- Testing
- Upper Extremity Neuromuscular Training Program, Usual Physiotherapy Care
- Where
- Canada
- Volunteers
- 33 people
- Sponsor
- Laval University
Lung Cancer
Intervention to Improve Supportive Care for Family Caregivers of Patients With Lung Cancer
Family caregivers play a crucial role in cancer patients care, as they are their principal source of support. It is well recommended to provide them with the resources, information and support needed to maintain a good health…
- Trial name
- NCT02531464
- Testing
- Supportive care
- Where
- Canada
- Volunteers
- 109 people
- Sponsor
- Laval University
Hip Osteoarthritis
Daily Activity and Gait Analysis After Viscosupplement Injection Among Hip Osteoarthritis Patients
The objective of this study is to assess the changes in daily physical activity and gait pattern, following a viscosupplement injection among a population who is suffering from hip osteoarthritis.
- Trial name
- NCT02086474
- Testing
- Hyaluronan, Bupivacaine
- Where
- Canada
- Volunteers
- 38 people
- Sponsor
- Laval University
Chronic Obstructive Pulmonary Disease
Glittre ADL-test: Responsiveness to Acute Bronchodilation in Chronic Obstructive Pulmonary Disease (COPD)
This project is aimed to assess the responsiveness of the Glittre ADL-test and the 1-Minute Sit-to-Stand test (1-Minute STST) to acute bronchodilation in patients with COPD.
- Trial name
- Glittre (NCT03071731)
- Testing
- Bronchodilators
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- Laval University
Musculoskeletal Disorder
Effect of an Exercise Program Designed for Orchestral Musicians
This study is a randomized clinical trial evaluating the effect of an exercise program designed specifically for orchestral musicians on performance-related musculoskeletal problems (PRMPs).
- Trial name
- NCT03288688
- Testing
- Exercise program and education
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Laval University
Obesity, Hyperoxia
Evaluation of the Risk of Hyperoxia-induced Hypercapnia in Obese Cardiac Surgery Patients
This study aims to evaluate the risk of hyperoxia-induced hypercapnia in post-op obese cardiac surgery patients. It will compare two oxygenation modes in terms of their effect on the arterial partial pressure of carbon dioxide…
- Conditions
- Obesity, Hyperoxia, Hypercapnia
- Trial name
- NCT02917668
- Testing
- FreeO2, Usual care
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Laval University
Chronic Obstructive Pulmonary Disease (COPD)
Chen-style Tai Chi in Pulmonary Rehabilitation for Chronic Obstructive Pulmonary Disease
This study will evaluate the effects of Chen-style Tai Chi compared to conventional exercise in pulmonary rehabilitation for COPD patients.
- Trial name
- NCT02370654
- Testing
- Tai chi, Conventional exercise
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- Laval University
Morbid Obesity, Bariatric Surgery Candidate
EPO2-PV: Evaluation of Pre-Oxygenation Conditions in Morbidly Obese Volunteer: Effect of Position and Ventilation Mode
The risk of complications associated with airway management in obese patients is significant. The results of pre-oxygenation allow a prolonged non-hypoxic apnea time for the clinician.
- Trial name
- EPO2-PV (NCT02121808)
- Testing
- NIPPV, Tidal volume
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Laval University
Obesity, Morbid, Bariatric Surgery Candidate
Duodenal Switch With a Standard Versus Long Alimentary Limb
The aim of this study was to determine if Biliopancreatic Diversion with Duodenal Switch (BPD-DS) with a longer strict alimentary limb at the expense of a shorter biliopancreatic limb will offer significant weight lost, but with…
- Conditions
- Obesity, Morbid, Bariatric Surgery Candidate, Metabolism Disorder
- Trial name
- Long_limb_DS (NCT03097926)
- Testing
- Long alimentary limb BPD-DS
- Volunteers
- 20 people
- Sponsor
- Laval University
Neoplasms
Beta-carotene and Alpha-tocopherol Chemoprevention of Second Primary Malignancies in Head and Neck Cancer Patients
Epidemiologic studies suggest that low dietary intakes and low plasma concentrations of antioxidant vitamins and minerals are associated with increased risks of cancer, especially for epidermoid tumors.
- Trial name
- NCT00169845
- Testing
- Alpha-Tocopherol and Beta-Carotene
- Where
- Canada
- Volunteers
- 540 people
- Sponsor
- Laval University
Pulmonary Disease, Chronic Obstructive, Healthy
Low Load, High-repetitive Elastic Band Resistance Training in COPD
Recent work have shown that low load, high-repetitive single limb resistance training, if compared to a control, can increase limb muscle function and functional exercise capacity in patients with chronic obstructive pulmonary…
- Trial name
- NCT02283580
- Testing
- Single limb, Two limb
- Where
- 2 sites in Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Laval University
Pulmonary Arterial Hypertension
Peripheral Muscle Microcirculation and Exercise-induced Blood Flow Distribution in Pulmonary Arterial Hypertension
Pulmonary artery hypertension (PAH) is a rare, severe disease, characterized by a progressive increase in pulmonary vascular resistance ultimately leading to right ventricular (RV) failure and premature death.
- Trial name
- NCT01520493
- Testing
- Submaximal exercises
- Where
- 2 sites in Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Laval University
Cardiovascular Disease, Inflammation
Impact of EPA and DHA Supplementation on Plasma Biomarkers of Inflammation (n3)
Subclinical inflammation is now indisputably recognized as a key etiological factor in the development of atherosclerosis and subsequent cardiovascular disease.
- Trial name
- n3 (NCT01810003)
- Testing
- High DHA, High EPA
- Where
- Canada
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Laval University
Metabolic Syndrome
Study of the Impact of Dairy Fat on Cardiovascular Health.
Market trends depicted by Agriculture and Agri-Food Canada suggest stagnation in cheese consumption, with potentially important impact on this key industry in Canada.
- Trial name
- HDL (NCT02106208)
- Testing
- Cheese diet, Butter diet, CHO diet
- Where
- 2 sites in Canada
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Laval University
Hypertension
Study of the Impact of Low Fat Dairy and High Fat Dairy Consumption on Daytime Ambulatory Blood Pressure
Market trends depicted by Agriculture and Agri-Food Canada suggest stagnation in cheese consumption, with potentially important impact on this key industry in Canada.
- Trial name
- GABA2 (NCT02763930)
- Testing
- Control diet, Milk diet, GABA-rich cheese diet
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Laval University
Human Papillomavirus Vaccines
Immunogenicity of One Dose of Gardasil and One Dose of Gardasil-9
This study will assess the immunogenicity of one dose of Gardasil and one dose of Gardasil-9
- Trial name
- NCT03431246
- Testing
- Gardasil and Gardasil-9
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Laval University
Coronary Artery Disease
EArly Discharge After Transradial Stenting of CoronarY Arteries in High-Risk Patients of Bleeding
RATIONALE: Transradial coronary stenting is associated with less risk of access site complications and bleeding compared to femoral approach. Major bleeding post-PCI is a strong independent predictor of mortality and MACE.
- Trial name
- EASY-B2B (NCT01084993)
- Testing
- Bivalirudin, Heparin
- Where
- Canada
- Volunteers
- 2,000 people
- Sponsor
- Laval University
Infarction, Myocardial
Comparaison of 2 SpO2 Level Measured by Pulse Oxymetry in Complications of Acute Coronary Syndrome.
During acute coronary syndrome, the American College of Cardiology and the American Heart Association recommend oxygen delivery to patients with less than 90% oxygen saturation.
- Trial name
- FreeO2 SCA (NCT03122210)
- Testing
- Automated oxygen administration
- Volunteers
- 60 people
- Sponsor
- Laval University