Clinical trials: sponsored by Laval University
Eating Habits
Impact of the COVID-19 Pandemic on Diet Quality and Food Insecurity: a NutriQuébec Sub-study
The unprecedented confinement and social distancing rules imposed by the fight against COVID-19 has forced the majority of the population worldwide to stay home for periods of time ranging from weeks to months.
- Trial name
- NCT04371848
- Where
- Canada
- Volunteers
- 2,465 people, healthy volunteers welcome
- Sponsor
- Laval University
Eating Habits
NutriQuébec: a Web-based Prospective Cohort Study to Monitor the Population's Eating Habits in the Province of Québec.
The epidemic of non-communicable diseases such as cardiovascular diseases and type 2 diabetes is attributable in large part to unhealthy eating habits and physical inactivity.
- Trial name
- NCT04140071
- Where
- Canada
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Laval University
Obesity, Morbid Obesity
Single Anastomosis Versus Standard Duodenal Switch
Bilio-Pancreatic diversion with Duodenal Switch (BPD-DS) is the most effective bariatric procedure in terms of long-term weight loss and remission rate of Type 2 Diabetes.
- Trial name
- SADI (NCT04767490)
- Testing
- Standard Duodenal Switch, Single Anastomosis Duodenal Switch
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Laval University
Physical Activity
Evaluation of a Smartphone-delivered Peer-led Physical Activity Counselling Program for Manual Wheelchair Users
Despite physical activity (PA) being a valuable modality for promoting health, the evidence for effective PA intervention strategies for manual wheelchair (MWC) users is underdeveloped.
- Trial name
- ALLWheel (NCT02826707)
- Testing
- SPPAC intervention
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Laval University
Respiratory Disease, Respiratory Failure
Clinical Evaluation of FreeO2 (Version 4) in All Patients Receiving Oxygen
Evaluation of automatic titration of oxygen with a new version of FreeO2 (V4)
- Conditions
- Respiratory Disease, Respiratory Failure, COPD Exacerbation, Asthma
- Trial name
- FreeO24G (NCT03119727)
- Testing
- FreeO2
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Laval University
Bulimia Nervosa, Binge-Eating Disorder
Pilot Study on the Validity of the Metacognitive Hub Model of Craving in Bulimia Nervosa (BN) and Binge Eating Disorders (BED)
Craving is defined as an irrepressible urge to consume certain products and represents one of the key factors in severe substance use disorders, as illustrated by its recent inclusion as a diagnostic criterion in the most recent…
- Trial name
- MetaBou (NCT05879679)
- Testing
- Food craving induction
- Where
- 3 sites in Canada, France
- Volunteers
- 60 people
- Sponsor
- Laval University
Respiratory Failure, Hypoxemia
OxyGap : Comparison Between Different Pulse Oximeter and With the Arterial Blood Gase
The oximeter is used to monitor intensive care patients undergoing oxygen therapy. It indicates pulsed oxygen saturation (SpO2), a reflection of arterial oxygen saturation (SaO2) which enables detection of hypoxemia and…
- Conditions
- Respiratory Failure, Hypoxemia, Hyperoxemia
- Trial name
- OxyGap (NCT04772183)
- Testing
- SpO2 and SaO2 comparison
- Where
- 2 sites in Canada
- Volunteers
- 300 people
- Sponsor
- Laval University
Oxygen Deficiency, COPD Exacerbation
FreeDom: Innovative Strategy for the Management of COPD Exacerbations
The main objective of the study is to assess the "FreeDom" innovative strategy (FreeO2 at Domicile) to reduce hospitalization duration in patients with COPD exacerbation.
- Trial name
- NCT03396172
- Testing
- Control, FreeDom
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Laval University
Cardiometabolic Risk
Combining a Mediterranean Diet With Physical Activity to Address Cardiometabolic Risk
There is little doubt scientifically that healthy eating, such as adhering to the Mediterranean diet (MedDiet) principles, is key for the prevention of cardiovascular disease (CVD).
- Trial name
- MEx (NCT03731013)
- Testing
- Mediterranean diet (MedDiet), Physical activity (PA), Mediterranean diet and physical activity
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Laval University
Medial Knee Osteoarthritis
Lateral Wedge Insoles With Arch Support in Knee Osteoarthritis
The purpose of this is to test lateral foot orthoses with different amount of wedging to find a model that predicts the optimal lateral inclination of foot orthosis based on biomechanical or feelings measures.
- Trial name
- NCT01909596
- Testing
- Neutral customized foot orthoses, 6° lateral customized foot orthoses, 10° lateral customized foot orthoses
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Laval University
Posterior Tibial Tendon Dysfunction
Biomechanical Effects of Three Types of Foot Orthoses in Individuals With Posterior Tibialis Tendon Dysfunction
Background : Posterior tibialis tendon dysfunction (PTTD) is characterized by a loss of function of the muscle caused by the degeneration of the tendon leading to a flattening of the arch.
- Trial name
- NCT06399237
- Testing
- Foot Orthoses
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- Laval University
Pancreas Adenocarcinoma, Pancreas Metastases
Pancreatic Cancer and Synchronous Liver Metastases Resection Following Neoadjuvant FOLFIRINOX
This is a prospective, pilot study from a single center. Patients will be evaluated and operated on by one of five surgeons with a subspeciality in hepato-biliary and pancreatic surgery.
- Conditions
- Pancreas Adenocarcinoma, Pancreas Metastases, Pancreas Cancer
- Trial name
- PDAC-LIV (NCT06349278)
- Testing
- Pancreatic resection and non-anatomic liver resections.
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Laval University
Overweight, Microbiota
Effects of Maple Syrup on Gut Microbiota Diversity and Metabolic Syndrome
It has been suggested that the actual obesity epidemy is related to chronic overconsumption of added or free sugars. The increasing popularity of artificial sweeteners attest the population willingness to reduce added sugars…
- Conditions
- Overweight, Microbiota, Endotoxemia, Metabolic Syndrome
- Trial name
- NCT04117802
- Testing
- Maple syrup
- Where
- Canada
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Laval University
Gastric Cancer, Gastric Adenocarcinoma
Near-infrared Imaging With Indocyanine Green for Detection of Peritoneal Metastases for Gastric Adenocarcinoma.
Peritoneal disease at initial presentation for patients with gastric adenocarcinoma (GA) is frequent, with 15-31% of patients presenting with peritoneal metastases (PM) at surgical exploration.
- Conditions
- Gastric Cancer, Gastric Adenocarcinoma, Peritoneal Carcinomatosis, Peritoneal Metastases
- Trial name
- NCT05687617
- Testing
- Indocyanine green
- Where
- 2 sites in Canada
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Laval University
Polyarthritis
Study of the Impact of Fatty Acids From Seal Oil on the Relief of Symptoms Associated With Rheumatoid Arthritis
This project proposes to conduct the first fully controlled and randomized clinical study demonstrating the impact of DPA-rich sea bass oil on the reduction of symptoms related to rheumatoid arthritis.
- Trial name
- NCT04688398
- Testing
- Seal oil, Control
- Where
- Canada
- Volunteers
- 130 people
- Sponsor
- Laval University
Post Traumatic Stress Disorder, Insomnia
RESILIENT - An Online Multidimensional Treatment to Promote Resilience After a Disaster: Randomized Controlled Trial Protocol
Background. The wildfires on May 1, 2016 in Fort McMurray, Alberta (Canada), destroyed approximately 2,400 homes and buildings and led to massive displacement of approximately 88,000 people.
- Conditions
- Post Traumatic Stress Disorder, Insomnia, Depression
- Trial name
- RESILIENT (NCT04808713)
- Testing
- Treatment
- Where
- Canada
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Laval University
Hypercholesterolemia, Familial, Calcification; Heart
Diet Quality and Coronary Artery Calcification in Adults With Heterozygous Familial Hypercholesterolemia
The overarching objective is to evaluate the relationship between diet and coronary artery calcification in patients with heterozygous familial hypercholesterolemia (HeFH). We will recruit adults with HeFH.
- Conditions
- Hypercholesterolemia, Familial, Calcification; Heart, Diet Habit
- Trial name
- FH-CAC (NCT04837638)
- Testing
- Diet
- Where
- Canada
- Volunteers
- 258 people, healthy volunteers welcome
- Sponsor
- Laval University
COVID-19, SARS-CoV-2 Infection
Physical and Cognitive Impairments in People Suffering From Long COVID
Of the 1,900,000 Canadians who have been infected by COVID-19, 8 to 15% will continue to experience COVID-19 related symptoms well after 12 weeks. The persistence of such symptoms is now defined as "long COVID" syndrome.
- Conditions
- COVID-19, SARS-CoV-2 Infection, Corona Virus Infection, Physical Disability
- Trial name
- NCT05216536
- Testing
- No intervention
- Where
- Canada
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Laval University
Vaping, Electronic Cigarette Use
Vaping Adverse Lung and Heart Events Cohort
This prospective study assesses the pulmonary and cardiovascular effets of vaping in adult electronic cigarette users with biannual visits and a 5-year follow-up.
- Trial name
- VapALERT (NCT06291597)
- Testing
- Vaping
- Where
- Canada
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Laval University
Chronic Pain, Musculoskeletal Pain
Pain Education Program Optimization (PEPO) Trial
The goal of this clinical trial is to compare two different modes of delivering a self-management program for chronic pain (independently vs. with additional support) on pain-related disability.
- Trial name
- PEPO (NCT06174246)
- Testing
- Pain self-management program, Additional support for self-management program
- Where
- Canada
- Volunteers
- 86 people
- Sponsor
- Laval University