Clinical trials: sponsored by Linkoeping University
Internet Treatment, Active Control
ICBT for Depression in Older Adults
The study was a randomized controlled trial investigating treatment effects against an active control condition. 101 self-recruited participants, aged 65 to 88 years, were included.
- Trial name
- ALM (NCT05269524)
- Testing
- Internet-delivered tailored cognitive behavior therapy
- Where
- Sweden
- Volunteers
- 101 people
- Sponsor
- Linkoeping University
Disseminated Pancreatic Cancer
Surgery for Liver Metastases From PDAC
Dissemination from pancreatic ductal adenocarcinoma (PDAC) occurs in clinical practice either in the form of recurrence after initial treatment with curative intent resection (metachronous) or more frequently prevails already at…
- Trial name
- ScanPan1 (NCT05271110)
- Testing
- Liver resection (ablation)
- Where
- Sweden
- Volunteers
- 64 people
- Sponsor
- Linkoeping University
Cancer
Pre-operative Prehabilitation in Cancer Surgery - Objective Recovery Assessment
To compare prehabilitation with physical exercise, psychological support, nutritional support and smoke/alchol stop to "standard of care" before canceer surgery.
- Trial name
- Popcorn (NCT05270577)
- Testing
- Prehabilitation, Standard care
- Volunteers
- 90 people
- Sponsor
- Linkoeping University
Pancreatic Cancer
Post-operative Drainage After Pancreaticoduodenectomy
The study compares regular use of surgical drains and no use of surgical drains in patients subjected to pancreaticoduodenectomy with expected low to intermediate risk for post operative pancreatic fistula.
- Trial name
- Drain 1 (NCT05270564)
- Testing
- Drain, No drain
- Where
- 2 sites in Sweden
- Volunteers
- 300 people
- Sponsor
- Linkoeping University
Adjustment Disorders
Work-focused Versus Generic Internet-based Interventions for Stress-related Disorders
Objective The aim of the current study was to evaluate the efficacy of an internet-based cognitive-behavioural intervention for stress-related disorders integrating work-related aspects (W-iCBT), compared with a generic iCBT and…
- Trial name
- NCT05240495
- Testing
- Internet-based Cognitive-behavioural therapy, Work-focused Cognitive-behavioural therapy
- Where
- Sweden
- Volunteers
- 182 people
- Sponsor
- Linkoeping University
Adjustment Disorders
Learning How to Recover From Stress - Pilot RCT
This randomized, controlled pilot trial evaluated the efficacy of a brief internet-based recovery training intervention targeting distressed employees.
- Trial name
- NCT05220592
- Testing
- Internet-based recovery training program
- Where
- Sweden
- Volunteers
- 69 people
- Sponsor
- Linkoeping University
Depression and Quality of Life Related to the Coronavirus Pandemic
ICBT for Mental Health Problems Related to the Coronavirus Pandemic
The study seeks to investigate the effects of a guided internet-based cognitive behavioral therapy (ICBT) programme a on adult mental health problems related to the current coronavirus pandemic.
- Trial name
- NCT04424212
- Testing
- Intervention group CoronaCope
- Where
- Sweden
- Volunteers
- 76 people
- Sponsor
- Linkoeping University
Caregiver Distress
Internet-based Treatment for Informal Caregivers in Lithuania LINGI
The purpose of this study is to evaluate efficacy of internet intervention for informal caregivers in Lithuania in reducing their care-giving burden.
- Trial name
- LINGI (NCT04052724)
- Testing
- Intervention group LINGI
- Where
- Sweden
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Linkoeping University
Coronary Artery Disease
Behavioral Interventions for Improvement of Adherence at Exercise-based Cardiac Rehabilitation (ECRA)
The purpose of this study is to investigate the effects of an extended behavioral intervention in exercise-based CR for improvement of physical capacity, adherence, psychological and physiological parameters, compared with usual…
- Trial name
- ECRA (NCT02895451)
- Testing
- Extended behavioral intervention
- Where
- Sweden
- Volunteers
- 170 people
- Sponsor
- Linkoeping University
Chronic Pain
Guided Internet-delivered Psychological Treatment for Chronic Pain
The aim of this feasibility study is to investigate if an addition of an internet-delivered psychological treatment, Acceptance and commitment therapy (IACT), can enhance the effect of an existing evidence-based interdisciplinary…
- Trial name
- MERIT (NCT05071547)
- Testing
- Guided internet-delivered acceptance and commitment therapy (ACT), Interdisciplinary Pain Rehabilitation Program (IPRP)
- Volunteers
- 300 people
- Sponsor
- Linkoeping University
Covid19, Cardiopulmonary Disease
Physiological Studies in Post-COVID-19 Syndrome, and the Association With DNA Methylation
The physiological derangements in subjects suffering from long-term symptoms following a Covid-19 infection (Post-COVID-19 Syndrome) are poorly understood and evaluated.
- Conditions
- Covid19, Cardiopulmonary Disease, Dyspnea, Lung Function Decreased
- Trial name
- NCT04859894
- Testing
- Physiological testing
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Linkoeping University
Major Depressive Disorder
Linköping University Relational and Interpersonal Psychotherapy Project
The study investigates the relative efficacy of Interpersonal Psychotherapy and Brief Relational Therapy for Major Depressive Disorder.
- Trial name
- LURIPP (NCT00763594)
- Testing
- Brief Relational Therapy, Interpersonal Psychotherapy
- Where
- Sweden
- Volunteers
- 41 people
- Sponsor
- Linkoeping University
Tendon Injuries, Soft Tissue Injuries
Early Controlled Loading on Conservative Treated Achilles Tendon Ruptures
The purpose of this study is to measure the mechanical properties of the tendon after conservative treated Achilles tendon ruptures with or without early controlled loading.
- Conditions
- Tendon Injuries, Soft Tissue Injuries, Achilles Tendon Rupture
- Trial name
- NCT02805751
- Testing
- Early loading on a training pedal, Tendon strain exercises, Early weight bearing
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Linkoeping University
Depressive Disorder, Major, Depressive Symptoms
ICBT for Depression - A Factorial Investigation of Kinds of Therapist Support and Self-/Expert-selected Content
The study is a factorial randomized controlled trial investigating the efficacy of difference versions of internet-administered cognitive behavioral therapy.
- Trial name
- NCT04260750
- Testing
- Internet-administered Cognitive behavioral therapy (ICBT)
- Where
- Sweden
- Volunteers
- 246 people
- Sponsor
- Linkoeping University
Pharmacokinetics, Antidepressive Agents
Serum Concentrations of Antidepressant Drugs in Pregnant Women - a Naturalistic Study
The study was a prospective naturalistic PK study of five frequently used antidepressant drugs in pregnant women; citalopram (CIT), escitalopram (ECIT), sertraline (SERT), mirtazapine (MIRT) and venlafaxine VEN) and their major…
- Conditions
- Pharmacokinetics, Antidepressive Agents, Pregnancy
- Trial name
- PAPA (NCT04806230)
- Testing
- sertraline, mirtazapine, venlafaxine, citalopram, escitalopram
- Where
- Sweden
- Volunteers
- 81 people
- Sponsor
- Linkoeping University
Pancreatic Ductal Adenocarcinoma
Survival Among Patients With Pancreatic Cancer Depending on Surgical Resection Rate
The primary aim of this population-based study is to investigate how a high resection rate of pancreaticoduodenectomy affects overall survival among patients aged ≥70 years with pancreatic ductal adenocarcinoma.
- Trial name
- NCT04802993
- Testing
- Resection rates
- Volunteers
- 5,123 people
- Sponsor
- Linkoeping University
Family Health
The Health Promoting Conversations for Families With a Critically Ill Relative
Objective: We investigated the outcomes of a nurse-led family intervention, Health Promoting Conversations, which focused on family functioning and wellbeing in families with a critically ill member.
- Trial name
- NCT03325049
- Testing
- The health-promoting conversations, Usual Care
- Where
- Sweden
- Volunteers
- 17 people
- Sponsor
- Linkoeping University
Generalized Anxiety Disorder
Self-selected or Predetermined Internet-based Treatment for Generalized Anxiety Disorder With Different Types of Support
This study evaluates two types of internet-based treatments for generalized anxiety disorder and two types of support. The treatments are a predetermined program for generalized anxiety disorder and a self-selected treatment.
- Trial name
- NCT03807193
- Testing
- Self-selected treatment, Predetermined treatment, Weekly support
- Where
- Sweden
- Volunteers
- 85 people
- Sponsor
- Linkoeping University
Maternal Obesity During Childbirth, Labor; Arrested Active Phase
Impact of Maternal BMI on Plasma Levels of Oxytocin During Labor Augmentation
The aim of this study is to examine the associations between maternal BMI and levels of oxytocin in maternal plasma during augmentation with oxytocin during first stage of labor in term pregnancy.
- Trial name
- NCT04093479
- Testing
- blood samples
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Linkoeping University
Heart Valve Disease, Ventricular Function
Magnetic Resonance Imaging and Fibrosis
Aortic valve disease causes impaired let ventricular function (LVF) due to hypertrophy, dilatation and diffuse myocardial fibrosis yet the prognostic effect of fibrosis, waiting time for operation and postoperative exercise…
- Conditions
- Heart Valve Disease, Ventricular Function, Fibrosis
- Trial name
- MRF (NCT02790008)
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Linkoeping University