Clinical trials: sponsored by Lund University
Normal Non-fluency
Gut Hormones After Meal Ingestion in Males Versus Females
The study hypothesis is that the release of gut hormones is increased proportionally to caloric load in each meal. Three different meals with different meal size will therefore be served and gut hormones determined.
- Trial name
- NCT01366781
- Testing
- Meal ingestion
- Where
- Sweden
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Lund University
Diabetes
Vildagliptin and the Glucagon Response to Hypoglycemia in Insulin-Treated Patients With Type 2 Diabetes
The purpose of this study is to explore whether the novel therapy of type 2 diabetes, vildagliptin, which inhibits dipeptidyl peptidase-4 (DPP-4), affects glucagon counterregulation during hypoglycemia in insulin-treated patients…
- Trial name
- NCT01219400
- Testing
- Vildagliptin
- Where
- Sweden
- Volunteers
- 28 people
- Sponsor
- Lund University
Healthy Volunteers Recruited From the General Population
Rapid Versus Slow Ingestion of Mixed Meal: Influence on Islet and Incretin Hormone Secretion in Healthy Volunteers
To test the influence of rapid versus slow ingestion of a mixed meal on insulin and incretin hormone secretion in healthy volunteers
- Trial name
- NCT01779622
- Testing
- Mixed meal
- Where
- Sweden
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Lund University
Obesity, Metabolic Syndrome
Effects of Dietary Fibre on Glucose Metabolism and Satiety
The experimental model is a semi-acute study where the purpose of the study is to evaluate food factors related to colonially derived regulation of glucose metabolism (and related parameters) and satiety in healthy subjects.
- Trial name
- NCT02093481
- Testing
- Test meal, Reference, Priming
- Where
- Sweden
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Lund University
Metabolic Syndrome, Insulin Resistance
Effect of a Synergistic Food Basket on Metabolic Syndrome Risk
The study evaluates the effect of a diet combining two different functional concepts on markers associated to cardiometabolic risk.
- Trial name
- NCT01527253
- Testing
- Synergistic food basket
- Where
- Sweden
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Lund University
HIV Infection, Tuberculosis
Immunosuppression in HIV-infected Patients With Tuberculosis in Ethiopia
Background: Tuberculosis (TB) and HIV are leading causes of disease and death in Subsaharan Africa. Antiretroviral therapy (ART) dramatically improves prognosis in HIV infection, but TB is still a common complication in…
- Conditions
- HIV Infection, Tuberculosis, Immunosuppression
- Trial name
- NCT01252537
- Where
- 5 sites in Ethiopia
- Volunteers
- 1,200 people
- Sponsor
- Lund University
Type 2 Diabetes
Alimentation and Diabetes in Lanzarote - ADILAN: a Pilot Trial
The purpose of this study is to compare two healthy diets (according to official Spanish guidelines) that have been shown to be effective in the treatment of type 2 diabetes in order to see if one is better than the other.
- Trial name
- ADILAN (NCT01891955)
- Testing
- Healthy diet A, Healthy diet B
- Where
- Spain
- Volunteers
- 14 people
- Sponsor
- Lund University
Type 2 Diabetes
Macronutrients and Gut Hormone Secretion
Study hypothesis is to examine the relative contribution of macronutrients for gut hormone secretion after a mixed meal in healthy volunteers and in subjects with type 2 diabetes.
- Trial name
- NCT01366794
- Testing
- Macronutrients
- Where
- 2 sites in Sweden
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Lund University
Metabolic Syndrome, Inflammation
Effects of Berries and Vegetables on Cardiometabolic Risk Markers and Cognitive Functions
The purpose of the study is to study the potential anti-inflammatory- and metabolic effects of polyphenols and dietary fibres in a product based on a mixture of several Swedish berries and vegetables that is known to have high…
- Conditions
- Metabolic Syndrome, Inflammation, Aging, Fermentation
- Trial name
- NCT01562392
- Testing
- berries and vegetables, control product
- Where
- Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lund University
Complication of Surgical Procedure
Factors Responsible for the Effectiveness of the Lund De-airing Technique
The Lund de-airing technique is employed for cardiac de-airing in open left heart surgery. It consists of two main elements namely, opening of both pleura after the patient is on CPB (cardiopulmonary bypass)and disconnection of…
- Trial name
- NCT01757704
- Testing
- Open pleurae & conventional filling of heart, Intact pleurae & staged filling of heart
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Lund University
Healthy, Type 2 Diabetes
Effects of Dipeptidyl Peptidase-4 (DPP-4) Inhibition on Hormonal Responses to Macronutrient Ingestion
The regulation by DPP-4 inhibition after ingested of different individual macronutrients is not known. Therefore, this study examines the influence of ingestion of fat, protein, glucose or mixed meal on the concentrations of…
- Trial name
- NCT00885638
- Testing
- Sitagliptin
- Where
- Sweden
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Lund University
Diabetes Mellitus
Improvement of Sensibility in the Foot in Diabetic Patients Induced by EMLA-application to the Lower Leg
Sensory input from the foot as well as all other body parts results in activation of sensory cortex. It is well known that the cortical body map is experienced-dependant and can rapidly change in response to changes in activity…
- Trial name
- NCT00959595
- Testing
- EMLA cream
- Where
- Sweden
- Volunteers
- 32 people
- Sponsor
- Lund University Hospital
Aortic Valve Disorder
CO2 Versus Lund De-airing Technique in Heart Surgery
To evaluate which of the two de-airing methods (CO2 insufflation vs. Lund de-airing technique) can shorten the left heart de-airing time and prevent or minimize cerebral air emboli during open surgery involving exposure of the…
- Trial name
- NCT00934596
- Testing
- Lund de-airing technique, carbon-dioxide insufflation
- Volunteers
- 20 people
- Sponsor
- Lund University
Obesity, Metabolic Syndrome
Role of Colonic Events on Metabolism and Appetite Control: A Synbiotic Approach
The purpose of the study is to evaluate food factors related to colonically derived regulation of glucose metabolism (and related parameters) and satiety using a semi-acute meal study in healthy subjects as experimental model.
- Trial name
- NCT01718418
- Testing
- test meal, reference
- Where
- Sweden
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Lund University
Metabolic Syndrome
Prebiotics as a Means to Modulate Gut Fermentation, Metabolism, Appetite and Cognition
This study aims at investigating the impact of colonic fermentation of intrinsic indigestible carbohydrates in cereal whole kernels after three days consumption, on metabolic variables and cognition.
- Trial name
- NCT01718431
- Testing
- test meal, reference meal
- Where
- Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lund University
Metastatic Colorectal Cancer
Chemotherapy and Avastin Followed by Maintenance Treatment With Avastin +/- Tarceva
Chemotherapy and bevacizumab is given for 4 months. Patients who have not progressed will continue with maintenance treatment with either bevacizumab (Avastin) alone, or bevacizumab and erlotinib (Tarceva).
- Trial name
- ACT (NCT00598156)
- Testing
- erlotinib (Tarceva), bevacizumab (Avastin)
- Where
- 15 sites in Denmark, Sweden
- Volunteers
- 249 people
- Sponsor
- Lund University Hospital
Frail Elderly
Case Managers to Frail Older People a Randomized Controlled Trial
The aim of is to test the effects of a model for care (case management) to older people with high healthcare consumption and functional dependency on healthcare consumption, quality of life, functional ability and experiences of…
- Trial name
- NCT01829594
- Testing
- Case management
- Where
- Sweden
- Volunteers
- 153 people
- Sponsor
- Lund University
Adjustment Disorders, Burnout, Professional
Outcome Study of the ReDO Intervention for Women With Stress-related Disorders
This project evaluates the outcomes of a work rehabilitation program, Redesigning Daily Occupations (ReDO), for women with stress-related disorders. The ReDO intervention focuses on how people compose their everyday lives.
- Trial name
- NCT01234961
- Testing
- Redesigning Daily Occupations, Care as usual
- Where
- Sweden
- Volunteers
- 84 people
- Sponsor
- Lund University
Dietary Prevention
Effects of Legumes on Glucose Regulation
Dietary prevention strategies are increasingly recognized as essential to combat the current epidemic of obesity and related metabolic disorders.
- Trial name
- NCT01706042
- Testing
- legume meal, white bread
- Where
- Sweden
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Lund University
Normal Non-fluency
Gut Hormones After Oral Versus Intravenous Amino Acids
The study hypothesis is that gut hormones are released after oral but not intravenous amino acids which result in stimulation of insulin secretion.
- Trial name
- NCT01366768
- Testing
- Oral amino acid mixture, Intravenous amino acid administration
- Where
- Sweden
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Lund University