Clinical trials: sponsored by Mahidol University
Lung Collapse, One-lung Ventilation
Brief Bronchial Suction for Lung Collapse During Uniportal VATS
The goal of this clinical trial is to learn whether a brief suction of the airway going to the surgical lung (bronchus) can help the lung collapse faster and more completely during uniportal video-assisted thoracoscopic surgery…
- Conditions
- Lung Collapse, One-lung Ventilation, Thoracic Anesthesia, Thoracic Surgery, Video-assisted
- Trial name
- NCT07660588
- Testing
- bronchial suction
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Frailty, Neuromuscular Blockade
Incidence of Residual Neuromuscular Blockade in Fraility in OncoGynae Surgery
Frailty among patients undergoing surgery is strongly associated with an elevated risk of adverse perioperative outcomes, heightened incidence of postoperative complications, increased mortality rates, and prolonged hospital…
- Conditions
- Frailty, Neuromuscular Blockade, General Anesthetic Drug Adverse Reaction, Gynecologic Cancer
- Trial name
- FIGO (NCT06216002)
- Testing
- Train of four nerve stimulator
- Where
- Thailand
- Volunteers
- 356 people
- Sponsor
- Mahidol University
Hematologic Disease and Disorders, Malignancies
Outcome of HSCT in Children at Ramathibodi Hospital
Firstly, to study the treatment outcomes of hematopoietic stem cell transplantation (HSCT) in patients with hematologic diseases, cancers, and other conditions treated at the Department of Pediatrics, Faculty of Medicine…
- Conditions
- Hematologic Disease and Disorders, Malignancies, Genetic Diseases
- Trial name
- NCT07857746
- Where
- Thailand
- Volunteers
- 200 people
- Sponsor
- Mahidol University
Obesity & Overweight, Normal Weight Adults
Long-term Iron Absorption and Loss in Women
Obese people typically have chronic low-grade inflammation. Based on short-term studies, this inflammation could affect the absorption, utilization, storage, and mobilization of iron, and individuals with inflammation might…
- Trial name
- NCT07855939
- Where
- Thailand
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Pain Management After Major Breast Surgery, Well Being After Major Breast Surgery
Quality of Recovery After Primary Breast Cancer Surgery Comparing Thoracic Paravertebral Block and Intravenous Lidocaine Infusion.
The goal of this clinical trial is to learn whether an intravenous lidocaine infusion (IVLI) works as well as a thoracic paravertebral block (TPVB) - the current standard nerve-block technique - for improving recovery after…
- Trial name
- NCT07823244
- Testing
- TPVB, IV Lidocaine infusion
- Where
- Thailand
- Volunteers
- 112 people
- Sponsor
- Mahidol University
Chronic Low Back Pain
Optimization of Lumbar Sensory Stimulation Parameters in Office Workers With Chronic Low Back Pain
This study aims to determine the optimal parameters of lumbar sensory stimulation in office workers with chronic nonspecific low back pain. Participants will attend two laboratory sessions.
- Trial name
- LSS-OPT (NCT07801729)
- Testing
- Lumbar sensory stimulation
- Where
- Thailand
- Volunteers
- 36 people
- Sponsor
- Mahidol University
Chronic Low Back Pain
Sensory Stimulation Belt for Chronic Low Back Pain in Office Workers
This randomized, double-blind, sham-controlled trial will evaluate the effectiveness of a sensory stimulation belt in office workers with chronic nonspecific low back pain.
- Trial name
- LSS-BELT (NCT07801755)
- Testing
- Active Sensory Stimulation Belt
- Where
- Thailand
- Volunteers
- 72 people
- Sponsor
- Mahidol University
Hypoxic-Ischemic Encephalopathy, Neonatal, Brain Injuries, Hypoxic-Ischemic
Mesenchymal Stem Cells With Cooling Therapy for Infants With Hypoxic-Ischemic Encephalopathy
Hypoxic-ischemic encephalopathy (HIE) is a serious condition in newborns caused by lack of oxygen and blood flow around the time of birth.
- Trial name
- SiSTEM-NEO (NCT07018739)
- Testing
- Wharton's jelly-derived mesenchymal stem cells, 0.9 % Normal Saline
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Mahidol University
Cervival Cancer
Hypofractionated Chemoradiotherapy for Cervical Cancer
The goal of this clinical trial is to evaluate whether hypofractionated whole pelvic or extended-field concurrent chemoradiotherapy can improve treatment access and efficiency while potentially providing superior oncologic…
- Trial name
- HYPOCx (NCT07709650)
- Testing
- Hypofractionated Chemoradiotherapy, Conventional Chemoradiotherapy, Concurrent chemotherapy
- Where
- Thailand
- Volunteers
- 250 people
- Sponsor
- Mahidol University
Bacteremia, Streptococcus Infection
Beta-lactam Plus Levofloxacin to Enhance Therapy in Streptococcal Septicemia
A double-blind randomized controlled trial comparing beta-lactam plus levofloxacin versus beta-lactam monotherapy for the treatment of Streptococcal bacteremia
- Trial name
- BLESS (NCT07240077)
- Testing
- Beta-lactam monotherapy, Beta-lactam plus levofloxacin combination therapy
- Where
- 4 sites in Thailand
- Volunteers
- 165 people
- Sponsor
- Mahidol University
Chronic Pain, Musculoskeletal Pain
National Survey of Chronic Occupational Pain in Thai Anesthesia Providers
The purpose of this nationwide cross-sectional survey is to determine the prevalence, multidimensional impacts, and associated factors of chronic occupational pain among anesthesiologists and nurse anesthetists in Thailand.
- Conditions
- Chronic Pain, Musculoskeletal Pain, Occupational Pain, Occupational Diseases
- Trial name
- NCT07778381
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Inflammatory Bowel Disease (IBD)
Benefit of Moderate Intensity Exercise in Patients With Clinical Quiescent Inflammatory Bowel Disease
The goal of this Randomised controlled trial is to investigate the effect of exercise on changes in quality of life in in patients with clinical quiescent Inflammatory bowel Disease.
- Trial name
- IBDEXERCISE (NCT07775794)
- Testing
- Exercise
- Where
- Thailand
- Volunteers
- 50 people
- Sponsor
- Mahidol University
Dengue Fever
Bridging Economics and Public Trust: A Study of Dengue Vaccine Cost-effectiveness and Acceptance in Thais Visiting Hospital
Study 1: Cost-effectiveness of TAK-003 Dengue Vaccination in Thailand This study aims to evaluate the cost-effectiveness of introducing the live-attenuated tetravalent dengue vaccine (TAK-003) into Thailand's national…
- Trial name
- NCT07759596
- Testing
- Objective 1- economic evaluation of Thai children with dengue vaccine
- Where
- Thailand
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Energy Expenditure, Body Composition
Energy Expenditure and Body Composition of Infants and Young Children (6-24 Months Old) in Asia
This project is a collaboration between International Atomic Energy Agency (IAEA), FAO Regional Office for Asia and The Pacific, and Mahidol University, Thailand to carry out the study on doubly-labeled water for assessment of…
- Conditions
- Energy Expenditure, Body Composition, Infants and Young Children, Infant and Young Child Feeding
- Trial name
- NCT06287697
- Testing
- No intervention
- Where
- Thailand
- Volunteers
- 391 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Non-pedunculated Colorectal Polyp Size > 20 mm
Comparison of Efficacy and Safety of Speedboat Device and Needle Knife for Colorectal Endoscopic Submucosal Dissection: a Multicenter Randomized Study
The goal of this clinical trial is to learn whether a new endoscopic device called the Speedboat works as well or better than the standard needle knife for removing large colonic nonpedunculated polyps.
- Trial name
- NCT07754955
- Testing
- Speedboat, Needle knife
- Where
- Thailand
- Volunteers
- 80 people
- Sponsor
- Mahidol University
IBD (Inflammatory Bowel Disease)
Efficacy of Melatonin Treatment on Sleep Quality Improvement in Inflammatory Bowel Disease Patients With Clinical Remission
Sleep disturbances are common in patients with inflammatory bowel disease (IBD) and are associated with increased disease activity and reduced quality of life.
- Trial name
- Melatonin IBD (NCT07737665)
- Testing
- Melatonin ("Circadin")
- Where
- Thailand
- Volunteers
- 90 people
- Sponsor
- Mahidol University
Pain, Chronic, Cancer Pain
Telemedicine Versus In-Person Follow-up for Cancer Pain Management: An Equity and Cost Analysis Comparison Using a Prospective Quasi-Experimental Design
Cancer is the second leading cause of death worldwide, with approximately 18.1 million new cases and 9.6 million deaths reported in 2018.
- Conditions
- Pain, Chronic, Cancer Pain, Cancer Related Pain
- Trial name
- NCT05628246
- Testing
- Telemedicine, In-person
- Where
- Thailand
- Volunteers
- 193 people
- Sponsor
- Mahidol University
Laparoscopic Inguinal Hernia Repair
The Plastic Covering Method for Self-gripping Mesh Placement in Laparoscopic Inguinal Hernia Repair
Inguinal hernia is one of the most-common surgical conditions. Incidence is about 27% in males and 3% in females.The treatment of this condition is inguinal hernia repair operation which can be approached with several techniques…
- Trial name
- NCT04394338
- Testing
- self-gripping mesh placement with plastic sheath in laparoscopic inguinal hernia
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Mahidol University
Foot Orthoses, Fasciitis, Plantar
Customized Foot Orthoses on Muscle Activity During Standing and Gait in Plantar Heel Pain
The present study will use a randomized controlled trial (RCT) to determine the effectiveness of customized foot orthosis (CFO) for the treatment of patients with PHP.
- Trial name
- NCT06318910
- Testing
- orthotic wedge, CFO
- Where
- Thailand
- Volunteers
- 75 people
- Sponsor
- Mahidol University
Dyslipidemia, Elevated Blood Lipids
Effects of Policosanol and Exercise on Fitness and Lipids in People With Elevated Blood Lipids
This study will evaluate the effects of policosanol supplementation, concurrent exercise training, and their combination on physical fitness, muscle recovery, inflammatory markers, and blood lipid profiles in adults with elevated…
- Conditions
- Dyslipidemia, Elevated Blood Lipids, Physical Fitness, Exercise Training
- Trial name
- NCT07710261
- Testing
- Policosanol, Concurrent Exercise Training
- Where
- Thailand
- Volunteers
- 120 people
- Sponsor
- Mahidol University