Clinical trials: sponsored by Mahidol University
Inflammation, Intraocular Pressure
Efficacy Comparison Study of Steroids to Control Post-operative Inflammation
Phacoemulsification is a quick method with less complication for cataract surgery. Due to the use of ultrasonic energy, it produced more post-operative inflammation than other methods.
- Trial name
- NCT01801774
- Testing
- Subtenon 20-mg triamcinolone injection
- Where
- Thailand
- Volunteers
- 140 people
- Sponsor
- Mahidol University
Anesthesia; Adverse Effect, Spinal and Epidural
Prophylaxis Ephedrine or Ondansetron Prevents Hypotension After Spinal Anesthesia for Cesarean Section
Maternal hypotension after spinal anesthesia in parturients undergoing cesarean section is a very common problem leading to several complications to both patients and their babies.
- Trial name
- NCT02194192
- Testing
- Ondansetron, Ephedrine
- Where
- Thailand
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Kidney Transplant
Impact of CYP3A5 Gene Polymorphisms on Tacrolimus Concentrations and Outcomes in Thai Transplant Recipients
Tacrolimus is a drug used commonly in kidney transplant patients to prevent graft rejection. Tacrolimus acts in a very narrow range in the blood for its optimum activity.
- Trial name
- NCT02377791
- Testing
- SNP: CYP3A5 gene polymorphisms
- Volunteers
- 170 people
- Sponsor
- Mahidol University
Anemia, Pregnancy Complications
Intravenous Versus Oral Iron in Late Pregnancy: Results of Treatment
The purpose of this study is to compare the efficacy of body iron storage replenishment between low dose intravenous iron and oral iron in late pregnancy.
- Trial name
- EIVF (NCT00746551)
- Testing
- Ferli-6® (Continental Pharm co., ltd.), Venofer® (Vifor AG, St. Gallen, Switzerland)
- Where
- Thailand
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Diffuse Large B-cell Lymphoma
The Response Study of Yt90-Zevalin in Patients With Diffuse Large B-cell Lymphoma After 6 Cycles of CHOP
The purpose of this study is to determine the effective of Yt90-Zevalin therapy in patients with diffuse large B-cell lymphoma that have achieved at least an unconfirmed partial remission after 6 cycles of CHOP therapy.
- Trial name
- NCT00440583
- Testing
- chemotherapy followed by Zevalin
- Where
- Thailand
- Volunteers
- 15 people
- Sponsor
- Mahidol University
Pain, Chronic
Development and Evaluation of a Methadone Protocol for Severe Chronic Pain Management
Methadone is a synthetic mu opioid agonist that has been proved as clinically effective in pain management. However, methadone usage for pain control in Thailand has been limited because physicians are not familiar with its…
- Trial name
- NCT02335398
- Testing
- Methadone
- Where
- Thailand
- Volunteers
- 34 people
- Sponsor
- Mahidol University
Nasal Obstruction Present Finding
Effectiveness of Oxymetazoline Added on Nasal Steroid in Rhinitis With Persistent Nasal Obstruction
Background Allergic rhinitis is a common health problem with a worldwide prevalence is 10-25%, and poses significant impact on the quality of life of the patients.
- Trial name
- NCT01847131
- Testing
- oxymetazoline
- Where
- Thailand
- Volunteers
- 50 people
- Sponsor
- Mahidol University
Transplantation of Kidney, Expanded Criteria Donor
Efficacy and Safety of Everolimus in de Novo Kidney Transplant Recipients of ECD or AKI Donors
Single center, open-label randomized-control trial Population: de novo 48 kidney transplant recipients (age 18-75 years) from ECD/AKI donors Compare: everolimus with low dose CNI and prednisolone versus standard immunosuppressive…
- Conditions
- Transplantation of Kidney, Expanded Criteria Donor, ECD
- Trial name
- NCT02314312
- Testing
- Everolimus + low dose cyclosporin A + prednisolone, Standard immunosupressive regimen
- Volunteers
- 48 people
- Sponsor
- Mahidol University
Encephalitis, Japanese B
Immunogenicity and Safety of Inactivated Vero Cell Derived Japanese Encephalitis Vaccine in Thai Children
Japanese encephalitis (JE) is the main cause of viral encephalitis in many countries of Asia including Thailand. Estimated annual mortality ranges from10,000-15,000 deaths, while the total number of clinical cases is about…
- Trial name
- JE0153 (NCT01408537)
- Testing
- JEVAC
- Where
- Thailand
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Vitamin D Deficiency
Vitamin D Status in Pediatric Asthma
The purpose of this study is to evaluate level of vitamin D in pediatric asthma and relationship between vitamin D and level control of asthma.
- Trial name
- NCT01432678
- Where
- Thailand
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Hallux Valgus
Mold Making Silicone Toe Separator on Hallux Valgus
The primary objective of this study is to investigate the effectiveness of mold making silicone toe separator on reducing the hallux valgus angle.
- Trial name
- NCT02220881
- Testing
- Mold making silicone toe separator, Observation
- Where
- Thailand
- Volunteers
- 90 people
- Sponsor
- Mahidol University
Gastroesophageal Reflux Disease
Efficacy of Imipramine for Treatment of Patients With Esophageal Hypersensitivity/ Functional Heartburn
Esophageal hypersensitivity/Functional heartburn are common among non-erosive reflux disease (NERD) patients who do not response to proton pump inhibitors.
- Trial name
- NCT01753128
- Testing
- imipramine
- Where
- Thailand
- Volunteers
- 83 people
- Sponsor
- Mahidol University
Child
Surgical Transversus Abdominis Plane Block in Pediatric Patients
The objective of this study to determine the effect of surgical transversus abdominis plane block and local infiltration for postoperative pain control in major abdominal surgery compare with control group.
- Trial name
- TAP (NCT01548027)
- Testing
- Local infiltration group, TAP block, No intervention
- Where
- Thailand
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Serum Bupivacaine Level, Periarticular Block
Plasma Concentrations of Bupivacaine After Peri-articular Injection in Total Knee Arthroplasty
Patients with knee arthroplasty usually performed under spinal anesthesia with a single-shot femoral nerve block and periarticular block, so we would like to know the plasma concentration of bupivacaine in these patients.
- Conditions
- Serum Bupivacaine Level, Periarticular Block, Total Knee Arthroplasty
- Trial name
- NCT01636869
- Testing
- Bupivacaine
- Where
- Thailand
- Volunteers
- 43 people
- Sponsor
- Mahidol University
Bradycardia, Neostigmine Adverse Reaction
0.6 vs. 1.2 mg Atropine Together With Neostigmine 2.5 mg on Heart Rate in Patient Receiving Muscle Relaxant
Balanced general anesthesia with neuromuscular blocking agents has been widely used for surgery.. At the end of surgery, neostigmine has been given for the reversal of neuromuscular blocking agents with several adverse effects…
- Conditions
- Bradycardia, Neostigmine Adverse Reaction, Adverse Reaction to Belladonna or Atropine
- Trial name
- NCT02186132
- Testing
- Atropine 0.6 mg, Atropine 1.2 mg
- Volunteers
- 40 people
- Sponsor
- Mahidol University
Stroke; Sequelae
Efficacy of Massage in Stroke Spasticity
Stroke is one of the common diseases in the elderly. It is the third ranking cause of death and affects health care system in our country. One of the most important consequences of stroke is spasticity.
- Trial name
- NCT01448980
- Testing
- Thai Traditional Massage (TTM), Physical therapy program
- Where
- Thailand
- Volunteers
- 396 people
- Sponsor
- Mahidol University
Patients With Chronic Rhinitis Who Failed Medical Treatment
A Randomized Study of Temperature-controlled and Bipolar Radiofrequency for Inferior Turbinate Reduction
Currently, there are several alternative treatments for patients with chronic rhinitis (CR) who failed medication. Although, most of the researches have been focusing on temperature-controlled RF (TCRF), the cost is a major…
- Trial name
- CompareRFIT (NCT01054521)
- Testing
- Temperature-controlled RF, Bipolar RF
- Where
- Thailand
- Volunteers
- 84 people
- Sponsor
- Mahidol University
Coronary Artery Disease, Valvular Heart Disease
The Cortisol Levels During Cardiac Surgery. The Comparison Between Etomidate and Thiopentone
During induction for cardiac surgery, patient hemodynamic stability is achieved by using anesthetic drugs which least affects hemodynamics such as benzodiazepines, etomidate.
- Trial name
- NCT01495949
- Testing
- etomidate, thiopentone
- Where
- Thailand
- Volunteers
- 92 people
- Sponsor
- Mahidol University
Anesthetic Technique, One-lung Ventilation
The Use of LMA-Proseal and Endobronchial Blocker for One Lung Anesthesia, Case Series
An observational pilot study to determine the success rate of using LMA Proseal in conjuction with endobronchial blocker to provide one-lung anesthesia for thoracic surgery.
- Trial name
- NCT02106273
- Testing
- Bronchial blocker (Coopdech, Arndt), LMA-ProsealTM
- Where
- Thailand
- Volunteers
- 29 people
- Sponsor
- Mahidol University
Hypersalivation, Prevention of Drooling
Efficacy of Intravenous Glyco-P® in Patients Undergoing Procedure That Require Anesthesia Service
This observational study was designed to prove clinical efficacy of the well known "glycopyrrolate" which is considered an orphan drug in Thailand.
- Conditions
- Hypersalivation, Prevention of Drooling, Bradycardia, Reversal of Muscle Relaxants
- Trial name
- NCT02102542
- Where
- Thailand
- Volunteers
- 65 people
- Sponsor
- Mahidol University