Clinical trials: sponsored by Mahidol University
Plantar Fasciitis
A Single-Blind Randomized Controlled Study Comparing the Efficacy of High-Intensity Laser Therapy and Focused Extracorporeal Shock Wave Therapy in Patients With Plantar Fasciitis
This randomized controlled trial aims to evaluate the efficacy of High-Intensity Laser Therapy (HILT) and Focused Extracorporeal Shock Wave Therapy (fESWT) in reducing pain in patients with plantar fasciitis.
- Trial name
- HILT (NCT07287046)
- Testing
- High power Laser therapy, Focused extracorporeal shock wave therapy
- Volunteers
- 28 people
- Sponsor
- Mahidol University
Dyspepsia and Other Specified Disorders of Function of Stomach
Holy Basil in The Treatment of Dyspepsia
The goal of this clinical trial is to evaluate whether holy basil extract can reduce gastric inflammation and improve symptoms in adult patients with dyspepsia.
- Trial name
- NCT07175272
- Testing
- Holy basil extract
- Where
- Thailand
- Volunteers
- 27 people
- Sponsor
- Mahidol University
Skeletal Class III Malocclusion, Transverse Maxillary Deficiency
Effects of Invisalign Palatal Expander vs Rapid Palatal Expander With Facemask in Growing Class III Patients
The goal of this clinical trial is to compare two types of palatal expanders used with a facemask in children who have skeletal Class III and a narrow upper jaw.
- Trial name
- NCT07485478
- Testing
- Invisalign Palatal Expander (IPE), Rapid Palatal Expander (RPE)
- Where
- Thailand
- Volunteers
- 24 people
- Sponsor
- Mahidol University
Patients With Early Breast Cancer Who Initiating Adjuvant Aromatase Inhibitor
Tailored Exercise to Reduce Aromatase Inhibitor Associated Musculoskeletal Symptoms
A randomized controlled study evaluating effect of tailored exercise compared to routine practice as a preventive measure of aromatase inhibitor associated musculoskeletal related symptoms in early breast cancer patients
- Trial name
- TAILOR-Ex (NCT07448558)
- Testing
- tailored exercise
- Where
- Thailand
- Volunteers
- 206 people
- Sponsor
- Mahidol University
Septic Shock
Septic Shock Hemodynamic Respond to Volume Resuscitation Versus Vasopressor Administration
The goal of this observational study is to learn about the change of hemodynamic response from intravenous fluid versus medical (vasopressor) resuscitation by echocardiogram in septic shock patient.
- Trial name
- ECHO-VEVA (NCT07438301)
- Testing
- Echocardiogram
- Where
- Thailand
- Volunteers
- 180 people
- Sponsor
- Mahidol University
Dengue Fever, Electronic Health Records
Prediction of Infectious Diseases in LMICs Using Electronic Health Record Data
Dengue is a rapidly emerging infectious disease in South and Southeast Asia. Definitive diagnosis requires laboratory testing (PCR or antigen testing) which are often unavailable in settings with highest incidence.
- Conditions
- Dengue Fever, Electronic Health Records, Prediction
- Trial name
- DiGi (NCT07432061)
- Testing
- No intervention
- Where
- Thailand
- Volunteers
- 1,000 people
- Sponsor
- Mahidol University
Ischemic Stroke, Hemorrhagic Stroke
Effects of Transcranial Electrical Stimulation in Stroke Individuals
The present study will use transcranial electrical stimulation (tES) with conventional physical therapy in sub-acute (at least 2 weeks after stroke onset) to chronic stroke within 2 years to investigate the effect on cortical…
- Conditions
- Ischemic Stroke, Hemorrhagic Stroke, Chronic Stroke, Subacute Stroke
- Trial name
- NCT06134921
- Testing
- transcranial direct current stimulation (Active), transcranial alternating current stimulation (active), Conventional physical therapy program
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Mahidol University
Hemorrhagic Stroke, Ischemic Stroke
Effects of tES Combined With CMDT Gait Training on Cognition, Cortical Activity, Spinal Motoneuron Excitability and Motor Performance in Stroke Individuals
The present study will use transcranial electrical stimulation (tES) which are transcranial direct current stimulation (tDCS) and transcranial alternating current stimulation (tACS) combined with conventional physical therapy and…
- Conditions
- Hemorrhagic Stroke, Ischemic Stroke, Subacute Stroke, Chronic Stroke Patient
- Trial name
- NCT07236216
- Testing
- High-definition transcranial direct current stimulation (Active), High-definition transcranial alternating stimulation (Active), Cognitive-motor dual task gait training
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Mahidol University
Dengue Disease, Dengue Haemorrhagic Fever
International Registry of Dengue Infection in Congenital Bleeding Disorders (DengueCBDR)
Dengue fever, a viral infection transmitted by Aedes mosquitoes, is a major health issue in tropical and subtropical regions. Around 20-30% of symptomatic patients developed Dengue Hemorrhagic Fever (DHF), which leads to impaired…
- Conditions
- Dengue Disease, Dengue Haemorrhagic Fever, Dengue Fever, Dengue Fever With Warning Signs
- Trial name
- DengueCBDR (NCT07409857)
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- Mahidol University
Sleep, Slow-wave Sleep, Sleep Enhancement, Sleep Optimization, Sleep Inertia
Association Between Slow Wave Activity and Sleep Inertia
Observational study: The goal of this observational study is to learn about the association between slow wave activity before awakening and post-awakening psychomotor vigilance task in time-fixed, 2-hour, simulated night naps in…
- Conditions
- Sleep, Slow-wave Sleep, Sleep Enhancement, Sleep Optimization, Sleep Inertia, Night Shift Work
- Trial name
- NCT07409883
- Testing
- Nap intervention
- Where
- Thailand
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Overactive Bladder (OAB), Menopause
Effect of Vaginal Estrogen on Alterations in the Urine Microbiome of Menopausal Women With Overactive Bladder
The goal of this Pre-Post Quasi-experimental study is to investigates the effect of vaginal estrogen therapy on changes in the urinary microbiome and its association with improvement in overactive bladder (OAB) symptoms in…
- Conditions
- Overactive Bladder (OAB), Menopause, Microbiome
- Trial name
- NCT06780163
- Testing
- 17β-estradiol 10 mcg
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Mahidol University
Acute Coronary Syndrome/ Myocardial Infarction, Coronary Artery Disease
Enabling Patient-Reported Outcomes Through Innovative Care - ACS (EPIC-ACS)
This study evaluates the effectiveness of an innovative care approach that integrates face-to-face education, motivational counseling, and mobile health (mHealth) support delivered via the LINE application among Thai older adults…
- Trial name
- NCT07390006
- Testing
- Innovative Care Approach, Usual Post-Acute Coronary Syndrome Care
- Where
- Thailand
- Volunteers
- 80 people
- Sponsor
- Mahidol University
Myofascial Pain Syndrome
Efficacy of Focused ESWT and Dry Needling Among Patients With Myofascial Pain Syndrome of the Upper Trapezius Muscle
Myofascial pain syndrome (MPS) is one of the most common causes of musculoskeletal pain. Among patients with MPS, the upper trapezius muscle appears to be the common muscle that generates pain in the area of upper extremity.
- Trial name
- NCT07397039
- Testing
- Focused Extracorporeal Shockwave Therapy (fESWT), Dry needling (DN)
- Where
- Thailand
- Volunteers
- 53 people
- Sponsor
- Mahidol University
Coronary Artery Disease (CAD), Coronary Artery Bypass Graft (CABG)
Effects of a Recovery-Promoting Program in Patients Undergoing CABG Surgery
Patients undergoing coronary artery bypass graft (CABG) surgery often experience physical limitations, psychological stress, and challenges during recovery after hospital discharge.
- Conditions
- Coronary Artery Disease (CAD), Coronary Artery Bypass Graft (CABG), Postoperative Recovery
- Trial name
- NCT07392021
- Testing
- Recovery Promotion Program for CABG patients, Standard Postoperative CABG Care
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Mahidol University
HIV
HIV Self-testing With Online Supervision for Vietnamese MSM
Although global rates of HIV infection have decreased overall, rates among men who have sex with men (MSM) in Southeast Asia are increasing.
- Trial name
- NCT05797961
- Testing
- HIV self-testing with online supervision, Control
- Where
- Vietnam
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Effectiveness of Toothbrush
The Study of Parental Toothbrushing Efficacy Assessment With Triple-Headed and Single-Headed Toothbrushes in Preschool Children With Developmental Disability
The Objectives 1. To evaluate the efficacy of dental plaque removal between triple-headed and single-headed toothbrushes in preschool children with developmental disabilities through parental brushing 2.
- Trial name
- NCT07373249
- Testing
- Triple-headed toothbrush
- Where
- Thailand
- Volunteers
- 24 people
- Sponsor
- Mahidol University
Fluoroquinolone, Adult
A Sticker Reminder Intervention to Promote IV-to-PO Fluoroquinolone Switching
A single-center, cluster-randomized controlled trial was conducted to determine the effect of Sticker reminder intervention on IV-to-PO switching of fluoquinolone.
- Trial name
- STICKER (NCT07361185)
- Testing
- Sticker reminder
- Where
- Thailand
- Volunteers
- 168 people
- Sponsor
- Mahidol University
Hypoxia, Airway Obstruction, Postoperative
Endotracheal Tube Suctioning Versus No Suctioning During Emergence From General Anesthesia
The goal of this study is to determine whether omitting tracheal suctioning immediately prior to extubation is non-inferior to routine tracheal suctioning with respect to early postoperative oxygenation among adult surgical…
- Conditions
- Hypoxia, Airway Obstruction, Postoperative, Sore Throat, Cough, Postoperative
- Trial name
- NCT07287293
- Testing
- Routine Endotracheal Suctioning, Omission of Endotracheal Suctioning
- Where
- Thailand
- Volunteers
- 408 people
- Sponsor
- Mahidol University
Hepatecellular Carcinoma, Cirrhosis
STOP HCC-GAAD-APAC-Thailand
Hepatocellular carcinoma (HCC) surveillance is frequently underutilized, and currently available biomarkers, such as alpha-fetoprotein (AFP), demonstrate suboptimal diagnostic performance.
- Conditions
- Hepatecellular Carcinoma, Cirrhosis, HBV Infection
- Trial name
- NCT07319299
- Testing
- GAAD score
- Where
- Thailand
- Volunteers
- 2,100 people
- Sponsor
- Mahidol University
Knee Osteoarthristis, Arthroplasties, Knee Replacement
Accelerated Rehabilitation in Individuals After Total Knee Arthroplasty
The primary aim of this double-blind randomized controlled trial is to evaluate the effectiveness of an accelerated rehabilitation protocol on knee joint function and quality of life in individuals undergoing TKA compared to…
- Trial name
- NCT07319546
- Testing
- Accelerated exercise, Routine exercise
- Where
- China
- Volunteers
- 32 people
- Sponsor
- Mahidol University