Clinical trials: sponsored by Mahidol University
Sarcopenia, Cirrhosis of the Liver
Oral Branched-chain Amino Acid Supplementation for Cirrhotic Patients With Sarcopenia
The goal of this clinical trial is to compare the nutritional parameters after 24-week supplementation of branched-chain amino acids in cirrhotic patients with low muscle mass.
- Trial name
- BCAASarcopenia (NCT06121492)
- Testing
- Branched-chain amino acid
- Where
- Thailand
- Volunteers
- 86 people
- Sponsor
- Mahidol University
Adhesive Capsulitis of the Shoulder
Intra-articular Corticosteroids Are Widely Used for Adhesive Capsulitis, But Alternatives Are Required for Patients With Contraindications. Hyaluronic Acid (HA) and Ketorolac Have Shown Individual Benefits. However, Evidence on Their Combination Remains Limited.
This randomized, double-blind trial compared a single intra-articular injection of moderate-molecular-weight hyaluronic acid (HA) plus ketorolac with ketorolac alone in patients with adhesive capsulitis.
- Trial name
- NCT07183436
- Testing
- Intra-articular Hyaluronic Acid and Ketorolac, Intra-articular Ketorolac
- Where
- Thailand
- Volunteers
- 56 people
- Sponsor
- Mahidol University
Cystitis, Recurrent, Urinary Tract Infections
Microbiome-Modulating Prophylaxis RCT: Antibiotic vs Gynoflor in Postmenopausal Women With Recurrent Cystitis
This open-label, parallel-group randomized controlled trial compares two prophylaxis strategies for recurrent urinary tract infection (rUTI) in postmenopausal women: (1) nightly oral nitrofurantoin 100 mg for 6 months versus (2)…
- Trial name
- microbiome (NCT07186465)
- Testing
- Nitrofurantoin, Gynoflor
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- Mahidol University
Old Age, Hip Fractures
Validity and Reliability of the Modified Delirium Diagnostic Tool - Provisional (DDT-Pro) (Thai Version) in Peri-operative Fragility Hip Fracture Patient
Nowadays, the number of hip fracture patients is increasing. As Thailand enters into an aging society, hip fractures are becoming more common. They are typically treated with surgery.
- Conditions
- Old Age, Hip Fractures, Delirium
- Trial name
- NCT06504251
- Testing
- Delirium Diagnostic Tool-Provisional ( DDT-Pro )
- Where
- Thailand
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Muscle Weakness
The Immediate Effect of Combined Terminal Knee Extension Exercise With Audible Cues
Typically, patients perform TKE by themselves after exercise prescription. The investigators thought that a lack of attention and preferred speed of patients might not provide the best outcome.
- Trial name
- NCT06565325
- Testing
- Exercise + Audible Cues, Exercise
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Mahidol University
Presbyphagia, Abnormal Tongue Pressure
Effect of Biofeedback Tongue Strengthening Program on Tongue Pressure and Swallowing Performance
Aging is often accompanied by a decline in bodily functions, including the swallowing process. Tongue-strengthening exercises have been shown to improve tongue strength and thickness in healthy adults and the elderly, thereby…
- Trial name
- NCT07080996
- Testing
- Strengthening training with biofeedback, Endurance training with biofeedback
- Where
- Thailand
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Plantar Fasciitis
Plantar Heel Pain: Multisegment Foot Motion and Muscle Function, FFI Translation, and Evaluation of Treatments
Plantar fasciitis (PF) is a prevalent musculoskeletal condition of plantar heel pain (PHP) that leads to pain, functional limitations, and reduced quality of life, especially among active adults aged 25 to 65.
- Trial name
- NCT03161314
- Testing
- Strengthening exercises, Stretching exercises
- Where
- 2 sites in Thailand
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Mild Cognitive Impairment
Effect of Action Observation Training on Gait Variables and Global Cognitive Functions
This study will investigate the effect of Action Observation Teaining (AOT) on gait variables and global cognitive functions in older adults with mild cognitive impairment (MCI).
- Trial name
- NCT03522389
- Testing
- AOT with gait training, Gait training, Education
- Where
- Thailand
- Volunteers
- 39 people
- Sponsor
- Mahidol University
Incomplete Spinal Cord Injury, Spastic Tetraplegia
Correlation Between Clinical Assessment and Neurophysiological Assessment in Spinal Cord Injury
This study is a cross-sectional study that aims to explore the correlation between clinical assessment and neurophysiological assessment in SCI.
- Conditions
- Incomplete Spinal Cord Injury, Spastic Tetraplegia, Spastic Paraplegia, Spinal Cord Injury
- Trial name
- NCT06680063
- Where
- Thailand
- Volunteers
- 22 people
- Sponsor
- Mahidol University
Pancreatic Masses
RCT Comparing Accuracy Among Franseen, Forward-bevel Westcott, and Fork-tip EUS-FNB Needle in Diagnosis of Solid Pancreatic Lesions
Endoscopic Ultrasound-Guided Fine Needle Aspiration (EUS-FNA) is a well-established technique for pancreatic tissue acquisition, offering a high diagnostic accuracy ranging from 78% to 95%, along with a favorable safety profile.
- Trial name
- NCT07032974
- Testing
- Franseen, Forward-bevel, Fork-tip
- Where
- Thailand
- Volunteers
- 108 people
- Sponsor
- Mahidol University
Artificial Intelligence (AI), Colonoscopy Education
Artificial Intelligence-assisted Colonoscopy, Tandem Study
The goal of this clinical trial is to evaluate effect of artifial intelligent (AI) system, Endoscopy as AI-powered Device (ENAD) on adenoma miss rate from colonoscopy underwent by trainee endoscopist.
- Conditions
- Artificial Intelligence (AI), Colonoscopy Education, Adenoma Colon Polyp
- Trial name
- NCT07023471
- Testing
- Group A (Trainee --> expert), Group B (Trainee +AI --> expert), Group C (Trainee --> expert + AI)
- Where
- Thailand
- Volunteers
- 364 people
- Sponsor
- Mahidol University
Common Bile Duct Stone
Laser vs Electrohydraulic Lithotripsy for Difficult CBD Stones
Common bile duct (CBD) stones are a frequent condition that can lead to severe complications if not treated. The standard approach involves endoscopic retrograde cholangiopancreatography (ERCP) with sphincterotomy and stone…
- Trial name
- NCT07030829
- Testing
- Laser Lithotripsy, Electrohydraulic Lithotripsy
- Where
- 2 sites in Thailand
- Volunteers
- 60 people
- Sponsor
- Mahidol University
Hypercholesterolemia
How Cricket Powder Affects Gut Microbiome and Cholesterol Metabolism
Cardiovascular disease (CVD) is the leading cause of death worldwide, including in Thailand. One of the major risk factors for CVD is dyslipidemia, or abnormal levels of cholesterol and other fats in the blood.
- Trial name
- CricketOnME (NCT07009756)
- Testing
- Cricket Powder
- Where
- Thailand
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Lower Gastrointestinal Bleeding, Small Bowel Bleeding
Urgent Panendoscopy in Patients Presenting With Hematochezia
Gastrointestinal bleeding is a significant emergency condition requiring prompt diagnosis. Current evidence presents a clinical paradox: urgent colonoscopy (within 24 hours) shows no clear benefit in several studies, while urgent…
- Trial name
- NCT06985277
- Testing
- Urgent endoscopy strategy, Standard colonoscopy with standard VCE group
- Where
- Thailand
- Volunteers
- 188 people
- Sponsor
- Mahidol University
Critical Illness, Fluid Overload
Intrarenal Venous Flow Change During Fluid Removal in Critically Ill Patients: A Prospective Exploratory Study
This clinical trial aims to study intrarenal venous flow patterns change, VExUS score change, and LUS score change during fluid removal treatment in critically ill patients
- Trial name
- NCT06216119
- Where
- Thailand
- Volunteers
- 52 people
- Sponsor
- Mahidol University
Foot Orthoses, Fasciitis, Plantar
Customized Foot Orthoses With Orthotic Wedges for Plantar Heel Pain
The present study will use a randomized controlled trial (RCT) to determine the effectiveness of customized foot orthosis (CFO) for the treatment of patients with PHP.
- Trial name
- NCT06319066
- Testing
- orthotic wedge, CFO
- Where
- Thailand
- Volunteers
- 120 people
- Sponsor
- Mahidol University
Daily Step Count, MASLD
The Efficacy of Pedometer-motivated Physical Activity for the Management of Patients With MASLD.
The study conducted a health survey among Thai adults in 2022 and found a significant increase in obesity and nonalcoholic fatty liver disease (NAFLD), leading to metabolic-associated steatotic liver disease (MASLD).
- Conditions
- Daily Step Count, MASLD, BMI, Metabolic Syndrome
- Trial name
- NCT06334666
- Testing
- Encourage using pedometer
- Where
- Thailand
- Volunteers
- 86 people
- Sponsor
- Mahidol University
Retinitis Pigmentosa
Safety and Efficacy of Stem Cell Small Extracellular Vesicles in Patients With Retinitis Pigmentosa
The aim of this clinical trials is to evaluate the safety and efficacy of intravitreal injection of GMP-compliant BM-MSC-derived sEVs in patients with retinitis pigmentosa.
- Trial name
- NCT06242379
- Testing
- GMP compliant-BM-MSC derived sEVs
- Where
- Thailand
- Volunteers
- 15 people
- Sponsor
- Mahidol University
Type 1 Diabetes
Self-compassion to Reduce Diabetes Distress in Persons With Type 1 Diabetes
This study explored the effects of self-compassion intervention on diabetes distress and self-compassion.
- Trial name
- NCT05070949
- Testing
- Mindful Self-Compassion
- Where
- 2 sites in Thailand
- Volunteers
- 34 people
- Sponsor
- Mahidol University
Transient Elastography, MASLD
Hepatic Elastography-Enhanced Lifestyle Modification in MASLD
The 2022 National Health Survey in Thailand revealed a substantial rise in obesity and metabolic dysfunction-associated steatotic liver disease (MASLD).
- Conditions
- Transient Elastography, MASLD, BMI, Metabolic Syndrome
- Trial name
- NCT06826807
- Testing
- Regular monitoring with transient elastography
- Where
- Thailand
- Volunteers
- 92 people
- Sponsor
- Mahidol University