Clinical trials: sponsored by Mahidol University
Melena Due to Gastrointestinal Hemorrhage
The Role of Push Enteroscopy in Patients With Passing Melena With Nondiagnostic EGD.
Melena is often caused by upper gastrointestinal (GI) bleeding; therefore, esophagogastroduodenoscopy (EGD) is the first preferred diagnostic tool. However, EGD fails to identify the bleeding source in about 25% of cases.
- Trial name
- NCT06574542
- Testing
- Push enteroscopy (PE), Colonoscopy
- Where
- Thailand
- Volunteers
- 77 people
- Sponsor
- Mahidol University
Anorexia, Cachexia
Olanzapine for Cancer Related Anorexia-cachexia Syndrome
Cancer anorexia-cachexia syndrome is one of the common conditions in cancer patients. Olanzapine has been demonstrated to reduce chemotherapy-induced anorexia.
- Trial name
- NCT06517199
- Testing
- Olanzapine 2.5 MG, Olanzapine 5 MG
- Where
- 2 sites in Thailand
- Volunteers
- 138 people
- Sponsor
- Mahidol University
Critically Ill, Pain, Postoperative
Ketamine-fentanyl VS Fentanyl for Analgosedation in SICU
This is a randomized, double-blinded study to evaluate the analgosedative effect of ketamine in a surgical intensive care unit. The patients who will receive continuous fentanyl infusion for either pain control or sedation will…
- Trial name
- NCT03879564
- Testing
- Ketamine, Normal saline
- Where
- Thailand
- Volunteers
- 118 people
- Sponsor
- Mahidol University
Intravenous, Thrombosis
Intravenous TNK vs TPA for AIS Treatment on MSU,a Prospective Multicenter RCT
Acute ischemic stroke is one of the devastating diseases that increase hospitalization, disabilities, and deaths worldwide. Current treatment with intravenous thrombolytic agent can help reduce disabilities and improve quality of…
- Conditions
- Intravenous, Thrombosis, Acute Ischemic Stroke
- Trial name
- NCT06498323
- Testing
- tenecteplase
- Where
- Thailand
- Volunteers
- 160 people
- Sponsor
- Mahidol University
Cryotherapy Effect
A Cryotherapy With Tranexamic Acid Versus Normal Saline in the Treatment of Melasma
This study aimed to evaluate the effectiveness of a precision cryotherapy via boosting mode combined with tranexamic acid versus normal saline in the treatment of melasma.
- Trial name
- NCT06491771
- Testing
- TargetCool
- Where
- Thailand
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Wrinkle
Efficacy and Safety of 675-nm Laser for Dorsal Hand Rejuvenation
This study aimed to evaluate efficacy and safety of 675-nm laser for dorsal hand rejuvenation in Thai patients. Twenty-six subjects aged 50 to 65 years diagnosed with wrinkle and solar lentigines on both dorsums of hands were…
- Trial name
- NCT06486727
- Testing
- Redtouch
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Tuberculosis (TB), Isoniazid Toxicity
Gene-guided N-acetyl Cysteine for Prophylaxis of Anti-tuberculous Drug- Induced Hepatitis
Tuberculosis (TB) remains a significant public health concern in Thailand and globally, especially in tropical regions, with pulmonary TB being predominant. Besides affecting the lungs, TB can also impact extrapulmonary organs.
- Conditions
- Tuberculosis (TB), Isoniazid Toxicity, Rifampicin Toxicity, Pyrazinamide Adverse Reaction
- Trial name
- NCT06484530
- Testing
- N acetyl cysteine
- Where
- Thailand
- Volunteers
- 116 people
- Sponsor
- Mahidol University
Low Back Pain
The Investigation of Underlying Mechanism of Lumbar Multifidus Muscle Activation Deficits
The goal of this clinical trial is to investigate mechanism underlying lumbar multifidus muscle (LM) activation deficits in adults with chronic low back pain (CLBP).
- Trial name
- NCT05961774
- Testing
- Transcranial magnetic stimulation, Neuromuscular electrical stimulation
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Mahidol University
Asthma, COPD
Small Airway Obstruction in Asthma, COPD, ACOS
This study was designed as retrospective chart review to test our hypothesis whether there are the differences in inflammatory and anti-inflammatory mediators between asthmatic and ACOS patients with small airway obstruction, and…
- Conditions
- Asthma, COPD, Asthma-COPD Overlap Syndrome
- Trial name
- NCT03423693
- Testing
- No any intervention
- Where
- Thailand
- Volunteers
- 230 people
- Sponsor
- Mahidol University
Migraine Disorders
Role of Ultrasound Guide Greater Occipital Nerve Block at Second Cervical Vertebra in Migraine Headache Prophylaxis
The goal of this randomized controlled study in Thailand. is to find if there is a role of local anesthetic greater occipital nerve block at Cervical spine level 2 under ultrasound guide in prophylaxis of episodic migraine and…
- Trial name
- NCT06432127
- Testing
- Bupivacaine
- Where
- Thailand
- Volunteers
- 108 people
- Sponsor
- Mahidol University
Implant Site Reaction
Effect of Static Magnetic Field on Dental Implant Stability.
To evaluate the effect of static magnetic field on dental implant to bone integration.
- Trial name
- NCT06226038
- Testing
- Magnet disc, Stainless steel
- Where
- Thailand
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Intertransverse Process Block, Thoracic Nerve Block
A Novel Intertransverse Plane Block: a Magnetic Resonance Imaging and Volunteer Study
Intertransverse process block (ITPB) is a thoracic nerve block technique where the LA is injected into the thoracic "intertransverse tissue complex" posterior to the superior costotransverse ligament (SCTL).
- Conditions
- Intertransverse Process Block, Thoracic Nerve Block, Thoracic Paravertebral Block
- Trial name
- NCT05538884
- Testing
- Intertransverse process block
- Where
- Thailand
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Gastroduodenal Ulcer
Hemostatic Forceps vs. Bipolar Electrocautery Probes for High-Risk Bleeding Gastroduodenal Ulcers
A randomized controlled trial to evaluate the efficacy of hemostatic forceps and bipolar electrocautery probes in patient with high risk bleeding gastroduodenal ulcers.
- Trial name
- NCT06393907
- Testing
- Hemostatic Forceps, Bipolar Electrocautery Probes
- Where
- Thailand
- Volunteers
- 150 people
- Sponsor
- Mahidol University
Rotator Cuff Tears
Combination of Vitamin C and N-Acetylcysteine to Improve Functional Outcome After Rotator Cuff Repair
The goal of this clinical trial is to learn if vitamin C and N-acetylcysteine work to improve shoulder functional score after rotator cuff repair. It will also learn about the safety of vitamin C and N-acetylcysteine.
- Trial name
- NCT06384833
- Testing
- Ascorbic acid, N-acetyl cysteine
- Volunteers
- 110 people
- Sponsor
- Mahidol University
Insertional Achilles Tendinopathy
Effectiveness of Extracorporeal Shockwave Therapy Combined With Platelet-rich Plasma in the Treatment of Chronic Insertional Achilles Tendinopathy
The goal of this clinical trial is to learn about the effectiveness of extracorporeal shockwave(ESWT) combined with platelet-rich plasma(PRP) to treat chronic insertional tendinopathy.
- Trial name
- NCT06384859
- Testing
- ESWT, PRP
- Where
- Thailand
- Volunteers
- 94 people
- Sponsor
- Mahidol University
Septic Shock, Adverse Event
Early Versus Conventional Cessation of Hydrocortisone in Septic Shock
Septic shock is one of the causes of death in ICU and hospital. Refractory shock is the problem which healthcare providers should recognize though it is difficult to handle with.
- Conditions
- Septic Shock, Adverse Event, Hydrocortisone, Hyperglycemia
- Trial name
- CESSHYDRO (NCT05818826)
- Testing
- normal saline solution, Hydrocortisone and normal saline solution
- Where
- Thailand
- Volunteers
- 160 people
- Sponsor
- Mahidol University
Intermittent Fasting, Weight Loss
The Effectiveness of Intermittent Fasting and Behavioral Economics Intervention on Weight Control in Obese Patients
This study is a parallel randomized controlled trial (RCT). To determine the effect of intermittent fasting, intermittent fasting with behavioral economics, and intensive lifestyle modification on nutritional status; the…
- Conditions
- Intermittent Fasting, Weight Loss, Behavioral Economic, Obese
- Trial name
- NCT06261229
- Testing
- Intermittent fasting, Intermittent fasting + Behavioral economic, Intensive Lifestyle Modification
- Where
- Thailand
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Exclusive Breastfeeding, Human Milk
Assessing Exclusive Breastfeeding Practice
This study was a longitudinal design. The questionnaire on exclusive breastfeeding was administered and was validated against the deuterium oxide dose-to-mother technique to assess human milk intake of babies aged 3 and 6 mo.
- Conditions
- Exclusive Breastfeeding, Human Milk, Breast Milk
- Trial name
- NCT05959460
- Testing
- Deuterium dose-to-mother method for assessing breastfeeding
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Fungal Foot Infection
Effectiveness and Safety of Whitfield's Solution, Zinc Oxide Nanoparticles Solution or Combination for the Treatment of Fungal Feet Infection
This study aimed to study the efficacy of Whitfield's solution, zinc oxide nanoparticles solution, and the combination of Whitfield's and zinc oxide nanoparticles solution in treating fungal feet infection.
- Trial name
- WhitfieldZinc (NCT05901961)
- Testing
- Whitfield solution, Zinc oxide nanoparticles solution, Combined Whitfield and Zinc oxide nanoparticles solution
- Where
- Thailand
- Volunteers
- 84 people
- Sponsor
- Mahidol University
Foot Dermatoses
Chlorhexidine Scrub, ZnO Nanoparticles Socks and the Combination for Prevention of Pitted Keratolysis
This study aimed to study the efficacy of chlorhexidine scrub, zinc oxide nanoparticles (ZnO-NPs) socks and the combination of chlorhexidine scrub and ZnO-NPs socks in prevention of pitted keratolysis.
- Trial name
- PKprevention (NCT04337749)
- Testing
- Chorhexidine scrub, ZnO-NPs socks, Combination of chorhexidine scrub and ZnO-NPs socks
- Where
- Thailand
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mahidol University