Clinical trials: sponsored by Mansoura University
Chronic Obstructive Pulmonary Disease, Pulmonary Emphysema
Volumetric HRCT in Stable COPD Patients.
This study evaluates the role of volumetric high-resolution computed tomography (HRCT) of the chest in assessing patients with stable chronic obstructive pulmonary disease (COPD).
- Conditions
- Chronic Obstructive Pulmonary Disease, Pulmonary Emphysema, Airway Obstruction
- Trial name
- NCT07809399
- Testing
- Volumetric HRCT chest, Spirometry and Body Plethysmography
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Mansoura University
Anterior Open Bite
Conventional Palatal Crib Versus Bonded Spurs for Anterior Open Bite Treatment
This randomized clinical trial aims to compare the effectiveness and patient acceptance of two orthodontic appliances-conventional palatal crib and bonded spurs-in the treatment of anterior open bite in children.Twenty children…
- Trial name
- NCT07509567
- Testing
- Conventional Palatal Crib, Bonded Spurs
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Mansoura University
Temporomandibular Joint Disc Displacement, With Reduction
Clinical and Jaw Tracking Assessment Following Intra-articular Injection of PRP and HA in TMJ Disc Displacement With Reduction
Assessment of intra-articular injection of hyaluronic acid and prp within TMJ using the Zebris jaw tracking device as an objective method
- Trial name
- NCT07643402
- Testing
- Hyaluronic Acid (HA) and Platelet rich plasma
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Mansoura University
Tooth Loss and Rehabillitation, Immediate Implant Placement in Mandibular Molar Extraction Sockets
Comparison Between Xenograft and Extended PRF as Jumping Gap Grafting Material Versus Natural Healing of the Socket Without Any Material.
This study aims to clinically and digitally evaluate immediate implants placed in mandibular molar extraction sockets and compare the outcomes of xenograft, e-PRF, and no grafting material within the jumping gap.
- Conditions
- Tooth Loss and Rehabillitation, Immediate Implant Placement in Mandibular Molar Extraction Sockets, Jumping Gap
- Trial name
- NCT07797452
- Testing
- Xenograft jumping gap filling material, e-PRF jumping gap filling material
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Type II Extraction Sockets in the Esthetic Zone
Hard and Soft Tissue Outcomes of Vestibular Socket Therapy Using Magnesium Membrane Versus Cortical Lamina in the Esthetic Zone.
This randomized clinical trial aims to compare two membrane materials used in Vestibular Socket Therapy (VST) technique during immediate implant placement in Type II extraction sockets in the esthetic zone.
- Trial name
- NCT07800377
- Testing
- Vestibular Socket Therapy Using Magnesium Membrane, Vestibular Socket Therapy Using Cortical Lamina
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Postoperative Wound Healing After Oral Cancer Surgery
Topical Phenytoin-Loaded Hydrogel Dressing for Postoperative Wound Management After Oral Squamous Cell Carcinoma Resection
This randomized, parallel-arm clinical trial evaluated whether a topical phenytoin-loaded hydrogel dressing could improve postoperative wound healing in patients undergoing surgical resection and reconstruction for locally…
- Trial name
- NCT07801157
- Testing
- Topical Phenytoin-Loaded Hydrogel Dressing, Conventional Postoperative Wound Care
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Mansoura University
Soft Tissue Augmentation at Dental Implants, Marginal Bone Loss
Autogenous Soft Tissue Grafts for Primary Closure Over Immediately Placed Dental Implants
The aim of this interventional study is to evaluate the best method to place the autogenous soft tissue grafts for primary closure over immediately-placed dental implants.
- Trial name
- BFP - FGG (NCT07327047)
- Testing
- Free autogenous soft tissue grafts
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Mansoura University
Diagnostic Role, Prognostic Role
Diagnostic and Prognostic Roles of Procalcitonin and Highly Sensitive C-Reactive Protein in Early Detection of Burn Sepsis
This study aimed to evaluate the value of procalcitonin and highly sensitive c-reactive protein as biomarkers for early detection of sepsis in patients with major burns.
- Conditions
- Diagnostic Role, Prognostic Role, Procalcitonin, Highly Sensitive
- Trial name
- NCT07791030
- Testing
- Measurement of Procalcitonin level, Measurement of c-reactive protein level
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Stem Cell Transplantation, Hematopoietic
Hematopoietic Stem Cell Transplantation Empowerment Program
The goal of this study is to evaluate the impact of an empowerment program for patients undergoing stem cell transplantation on their clinical outcomes.
- Trial name
- HSCT-EP (NCT07781046)
- Testing
- Empowerment program
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Dental Anxiety, Fear
Acupressure and Hand Massage for Reducing Anxiety During Dental Local Anesthetic Injections in Children
This study aims to compare the effects of acupressure ,hand massage , and routine behavioral management on anxiety in children undergoing dental local anesthetic injections .
- Trial name
- NCT07779837
- Testing
- acupressure, hand massage
- Where
- Egypt
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Breast Advanced Malignancies
TDXD in Metastatic HER2-Positive Breast Cancer
A single-center observational study (retrospective + prospective) evaluating the real-world efficacy and toxicity profile of Trastuzumab Deruxtecan (T-DXd) in adult female patients with HER2-positive metastatic breast cancer…
- Trial name
- NCT07778407
- Testing
- Trastuzumab deruxtecan (T-DXd)
- Where
- Saudi Arabia
- Volunteers
- 25 people
- Sponsor
- Mansoura University
Dental Implants, Edentulous Jaw
Passive Fit of Implant-Supported Frameworks: Digital vs Conventional Impressions
This randomized crossover clinical trial compares the passivity of fit of complete-arch mandibular implant-supported frameworks fabricated using three impression techniques: a non-calibrated splinted digital scan body system…
- Conditions
- Dental Implants, Edentulous Jaw, Passive Fit
- Trial name
- NCT07778199
- Testing
- IO-Connect Digital Impression, Reverse Scan Body Digital Impression, Conventional Splinted Impression
- Where
- Egypt
- Volunteers
- 8 people
- Sponsor
- Mansoura University
Breathing Exercises
Breathing Exercises on Lung Function
aim of this study is to evaluate the efficacy of pulmonary rehabilitation program as a non-pharmacological treatment method to: Improve functional capacity as assessed by six-minute walking distance (6MWD) test.
- Trial name
- NCT06472167
- Testing
- Breathing exercises
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University Hospital
Diaphragm Electrical Activity, COPD (Chronic Obstructive Pulmonary Disease)
Effect of Electrical Diaphragmatic Stimulation on Chronic Obstructive Pulmonary Disease
Respiratory muscle dysfunction is a common consequence of chronic obstructive pulmonary disease (COPD). This technique consists of placing electrodes on the skin at locations near the motor points of the diaphragm, transmitting…
- Trial name
- NCT07020299
- Testing
- Device : Digital electrical muscle stimulator is applied to induce diaphragm contraction.
- Where
- Egypt
- Volunteers
- 128 people
- Sponsor
- Mansoura University Hospital
Lung Cancer
Demographics of Lung Cancer in Females
Lung cancer has been the most common and fatal type of cancer; indeed worldwide incidence of lung cancer is alarming. It is considered a leading cause of cancer- related deaths among males and females due to environmental…
- Trial name
- NCT07122245
- Testing
- Demographics and risk factors of lung cancer
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Mansoura University Hospital
Chronic Obstructive Pulmonary Disease
Atopy and Frequency of Exacerbation in Chronic Obstructive Pulmonary Disease Patients
Chronic Obstructive Pulmonary Disease (COPD) is a heterogeneous lung condition characterized by chronic respiratory symptoms (dyspnea, cough, sputum production and/or exacerbations) due to abnormalities of airways (bronchitis…
- Trial name
- NCT06518473
- Testing
- Skin prick test
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University Hospital
Allergic Asthma
Changes in Eosinophil Cationic Protein and Sputum Eosinophils Following Allergen Immunotherapy
Asthma is a chronic heterogeneous inflammatory airway disease affecting millions worldwide and remains a major global health burden.
- Trial name
- NCT07694947
- Testing
- Allergen Immunotherapy Extract
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University Hospital
TMD, Disc Displacement
Conventional, Additive and Subtractive Occlusal Splints for TMDs
This study is aiming to clinically compare between occlusal splints produced by conventional, subtractive and additive techniques in regard to patient satisfaction.
- Trial name
- TMD - TMJ - DD (NCT07371078)
- Testing
- Conventional Stabilizing Splint, Milled Stabilizing Splint, 3D Printed Stabilizing Splint
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Maxillary Transverse Deficiency (Posterior Crossbite) in Early Adolescent Patients
Posterior Resin Bite Turbos Effect on Maxillary Expansion Using a HYRAX Expander in Early Adolescents
This randomized controlled clinical trial aims to evaluate the effect of posterior disarticulatory resin bite turbos on the rate of maxillary expansion using a HYRAX expander in early adolescent patients.
- Trial name
- HYRAX_ RME_SME (NCT07739498)
- Testing
- Intervention 1: HYRAX expander with posterior disarticulatory resin bite turbos, Intervention 2 (Control): HYRAX expander alone
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Mansoura University
Marginal Bone Loss Around Implants
Radiographic and Retention Evaluation Over Seven Years for Four Implant Retained Overdenture
ABSTRACT Statement of the problem: Insufficient long-term retrospective data is evaluating marginal bone loss and retention of four-implant Locator-retained mandibular overdentures.
- Trial name
- NCT07536776
- Testing
- implant retained overdenture, four dental implant with locator attachment
- Where
- Egypt
- Volunteers
- 27 people
- Sponsor
- Mansoura University
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