Clinical trials: sponsored by Mansoura University
Non-Muscle Invasive Bladder Cancer
Omega-3 Polyunsaturated Fatty Acids and Non-Muscle Invasive Bladder Cancer
The investigators hypothesize that omega-3 polyunsaturated fatty acids (n-3 PUFAs) might have a role in prevention of the recurrence of non-muscle invasive bladder cancer (NMIBC).
- Trial name
- NCT04664816
- Testing
- n-3PUFAs Treatment
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Mansoura University
Nocturnal Enuresis
The Safety and Efficacy of Fluoxetine for Refractory Primary Mono-symptomatic Nocturnal Enuresis in Children
To determine whether there is a role for the selective serotonin reuptake inhibitors, fluoxetine, as therapy in the treatment of refractory primary monosymptomatic nocturnal enuresis in children , and whether there are side…
- Trial name
- NCT04676139
- Testing
- Fluoxetine
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Steroid-Induced Glaucoma
Management Steroid Induced Glaucoma
Purpose: To assess the safety and efficacy of Viscotrabeculotomy Versus trabeculectomy with MMC for the management of medically uncontrolled steroid induced glaucoma.
- Trial name
- NCT04673201
- Testing
- Viscotrabeculotomy Versus trabeculectomy with "MMC"
- Where
- Egypt
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Response Assessment in Newly Diagnosed RA Patients at 3rd Month Was Evaluated by DAS28 and ACR in Relation to JAK Expression
JAK2 Mutation May Predict Response and Guide First Line Treatment in Rheumatoid Arthritis
This study included 76 newly diagnosed RA patients and 50 matched controls. Basal JAK2 mutation was assessed by PCR in blood samples, TNF-α and IL 6 were measured by ELISA in serum of patients and controls.
- Trial name
- NCT04667988
- Testing
- JAK expression
- Where
- Egypt
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Prostate Hyperplasia, Transurethral Incision Of The Prostate
Ejaculatory Sparing Transurethral Incision Of The Prostate (ES-TUIP) Versus Conventional TUIP
In this study, Investigators planned to compare ejaculatory sparing and non-ejaculatory sparing (conventional) TUIP using both subjective and objective assessment tools for the degree of deobstruction.
- Conditions
- Prostate Hyperplasia, Transurethral Incision Of The Prostate, Ejaculatory Dysfunction
- Trial name
- NCT03176017
- Testing
- Ejaculatory sparing TUIP, Conventional TUIP
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Breast Cancer
Reconstruction of Partial Mastectomy Defects With Pectoralis Myo-glandular Local Flap.
Increasing number of breast cancer patients are being treated with conservative surgery; without the need for mastectomy. The cosmetic sequel of breast conservative surgery can be unsatisfactory to the patient and may necessitate…
- Trial name
- NCT04091958
- Testing
- Pectoralis myo-glandular flap reconstruction.
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Mansoura University
Incontinence, Urinary Incontinence
Pharmacological Enhancement for Nocturnal Incontinence in Orthotopic Bladder Substitute
In this randomised trial, we hypothesised that mebeverine could enhance nocturnal continenece of Orthotopic Bladder Substitute (OBS) patients by decreasing the frequency and reduce maximum amplitude of uninhibited contractions of…
- Conditions
- Incontinence, Urinary Incontinence, Urinary Bladder Cancer
- Trial name
- NCT04635566
- Testing
- mebeverine 200 mg sustained-release (Coloverine® SR, Chemipharm pharmaceutical, Egypt) one time/day at the evening.
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Mansoura University
Benign Breast Disease
Risk Factors for Benign Breast Disease
Benign diseases of the breast are common clinical conditions that affect young women. Complaints related to the breast often cause significant discomfort and mental stress.
- Trial name
- NCT04127422
- Where
- Egypt
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Anal Fistula
Rerouting Seton Versus LIFT for Complex Anal Fistula
This study aims to compare the efficacy of two surgical techniques in treatment of complex anal fistulas. The first technique involves rerouting of the fistula tract with placement of a vessel loop seton around the internal anal…
- Trial name
- NCT04616911
- Testing
- Rerouting seton, LIFT
- Where
- Egypt
- Volunteers
- 77 people
- Sponsor
- Mansoura University
Covid-19, Drug Effect
New Treatment for COVID-19 Using Ethanol Vapor Inhalation .
Since ARDS is a major complication of COVID - 19 with subsequent formation of non-cardiogenic pulmonary edema , worsening the oxygenation of the patients and foamy and even bloody sputum formation, so the idea is to use alcohol…
- Trial name
- NCT04554433
- Testing
- Ethanol with Asprin
- Volunteers
- 80 people
- Sponsor
- Mansoura University
Bladder Cancer
The Role of mRNA-based Urine Test (Xpert Bladder Cancer Monitor) in Predicting the Need for Second Look Biopsy After Transurethral Resection of Non Muscle-invasive Bladder Tumor.
The Xpert BC Monitor is an mRNA-based urinary marker test for BC surveillance which measures the levels of five target mRNAs (ABL1, ANXA10, UPK1B, CRH and IGF2) from a voided urine sample by real-time RT-PCR.
- Trial name
- NCT04603612
- Testing
- Primary TURBT
- Where
- Egypt
- Volunteers
- 254 people
- Sponsor
- Mansoura University
Posterior Spine Surgery
Kyphoscoliosis Surgery: Blood Conservation and Analgesia
Since the first spinal fusion by Hibbs 1911, yet anesthesia for correction of scoliosis is challenging due to frequently associated co-morbidities, the extensive nature of surgery and liability for many complications.
- Trial name
- NCT03319563
- Testing
- Local anesthetic-epinephrine, Saline
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Mansoura University
Breast Cancer, Hepatitis C
Association of Hepatitis C Virus With Breast Cancer
Hepatitis C viral infection is a major health problem in Egypt. The management of breast cancer patients is often complicated by the presence of associated HCV infection.
- Trial name
- NCT04090164
- Where
- Egypt
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Chronic Knee Osteoarthritis
Ultrasound-guided Monopolar Versus Bipolar Radiofrequency Ablation for Genicular Nerves in Chronic Knee Osteoarthritis
Radiofrequency ablation of the genicular nerves using ultrasound is safe and effective for treating intractable knee osteoarthritis pain by using either monopolar or bipolar radiofrequency ablation.
- Trial name
- NCT04112264
- Testing
- Monopolar radiofrequency ablation, Bipolar radiofrequency ablation
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Mansoura University
Dysfunctional Uterine Bleeding
Misotac vs Combined Oral Contraceptive Pill in the Treatment of Symptomatic Isthmocele
Isthmocele is a growing concern as a cause of abnormal uterine bleeding, especially post menstrual bleeding which may be present in up to 82% of these cases (Iannone et al 2019).
- Trial name
- NCT04579965
- Testing
- medical treatment of isthmocele
- Volunteers
- 50 people
- Sponsor
- Mansoura University Hospital
Pneumonia, Covid19
The Role of Sodium Bicarbonate as Adjuvant Treatment of Computed Tomography Identified COVID-19 Pneumonia
To report the possible role of S.B 8.4% in the treatment of COVID-19pneumonia.
- Trial name
- NCT04374591
- Testing
- Sodium Bicarbonate
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Mansoura University
Ideal Time Interval
The Ideal Time Interval Between Repeated Shock Wave Lithotripsy Sessions For Renal Stones: A Randomized Controlled Trial
There is no consensus about the required time intervals between repeated SWL sessions applied for renal stones with some centers waiting for 3 days, others for one week and others up to one month to repeat lithotripsy.
- Trial name
- NCT04575480
- Testing
- Shock Wave Lithotripsy for renal stone.
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Mansoura University
Abdominoplasty
Erector Spinae Plane Block Versus Transversus Abdominis Plane Block in Abdominoplasty Surgery
Abdominoplasty is one of the most popular body-contouring procedures. Patients that undergo body-contouring abdominoplasty usually have important analgesic requirements.
- Trial name
- NCT03940885
- Testing
- Erector spinea plane block group, Transversus abdominis plane block, Control group
- Where
- Egypt
- Volunteers
- 69 people
- Sponsor
- Mansoura University
Emesis
Evaluation of Meclizine Orodispersible Tablet Pharmacokinetic in Human Volunteers
The main goal of this study is to develop a new oro-dissolvable/dispersible tablet that will augment the dual rapid absorption of MCZ from the buccal cavity as well as prolonging that from the GIT.
- Trial name
- NCT04564144
- Testing
- Meclizine Hydrochloride
- Where
- Egypt
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Proximal Femur Fracture
Which Analgesia is Better for Proximal Femoral Fractures?
This patient population is typically elderly and frail. They are at risk of adverse effects secondary to inadequate pain management such as prolonged admissions and poor functional outcomes.
- Trial name
- NCT04309539
- Testing
- Fascia iliaca block, combined LFCN block with PENG block
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
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