Clinical trials: sponsored by Marmara University
Restorative Experiences, Esthetic Restorations
The Effect of the Mamelon Effect on the Perception of Smile Esthetics
This study aimed to evaluate the role of the mamelon effect on the perception of smile esthetics. A single portrait image was digitally modified by using the Photoshop CC (Adobe, USA) software program to create the mamelon…
- Conditions
- Restorative Experiences, Esthetic Restorations, Perception
- Trial name
- MamelonEffect (NCT07379671)
- Testing
- Online Survey
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Marmara University
Overweight and Obesity
Neuromuscular Balance Exercise Effects in Overweight and Obese Individuals
This randomized controlled study aims to evaluate the effects of adding neuromuscular balance exercises to exercise programs on functional capacity, balance, and physical fitness in individuals with obesity.
- Trial name
- NCT07372157
- Testing
- Aerobic and strength training, Neuromuscular balance exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Marmara University
Lumbar Disc Herniation, Lumbar Radiculopathy
The Role of Temporal Changes in Pain Response After Transforaminal Epidural Steroid Injection on Treatment Success
Transforaminal epidural steroid injection (TFESI) is a commonly used minimally invasive procedure for the treatment of lumbar radicular pain secondary to disc herniation.
- Conditions
- Lumbar Disc Herniation, Lumbar Radiculopathy, Radicular Low Back Pain, Sciatica
- Trial name
- NCT07367191
- Testing
- Transforaminal epidural steroid injection
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Marmara University
Intracranial Hemorrhages
Validation of Falls Decision Rule to Exclude Intracranial Bleeding in Geriatric Fall Patients
Although falls are the most important cause of intracranial hemorrhage in the population over 65, studies have shown that bleeding occurs in only 5% of geriatric patients who fall.
- Trial name
- NCT06525727
- Testing
- Falls Decision Rule
- Where
- Turkey (Türkiye)
- Volunteers
- 800 people
- Sponsor
- Marmara University
Maxillary Sinus Augmentation, Posterior Maxillary Atrophy
Histologic and Histomorphometric Evaluation of Lateral Maxillary Sinus Augmentation With or Without Platelet-Rich Fibrin
This study evaluates bone healing after lateral maxillary sinus lift surgery performed prior to dental implant placement. This surgical procedure is commonly used when there is insufficient bone height in the upper jaw to support…
- Trial name
- NCT07348198
- Testing
- Lateral Maxillary Sinus Augmentation With DFDBA, Lateral Maxillary Sinus Augmentation With DFDBA and PRF
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Marmara University
Lateral Elbow Tendinopathy (Tennis Elbow)
Diagnostic Accuracy of the Clinical Tests and the Ultrasonography in Lateral Elbow Tendinopathy
Lateral elbow tendinopathy (LET) is the most common cause of elbow pain. Even though provocation tests such as Cozen's test, Mill's test or Maudsley test; musculoskeletal ultrasound or magnetic resonance imaging can be used for…
- Trial name
- NCT07347873
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Marmara University
Urinary Stone, Renal Injury
Urinary NGAL and KIM-1 After ESWL
The goal of this prospective observational study is to evaluate the effect of different time intervals between extracorporeal shock wave lithotripsy (ESWL) sessions on renal injury using urinary biomarkers in patients with…
- Trial name
- NCT07341269
- Testing
- No Interventions, No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Marmara University
Intraoperative Oxygenation and Pulmonary Mechanics
Effects of Magnesium Sulfate on Oxygenation and Lung Mechanics During One-Lung Ventilation
This prospective observational study aims to evaluate the effects of intravenous magnesium sulfate on intraoperative oxygenation and lung mechanics in patients undergoing thoracic surgery with one-lung ventilation.
- Trial name
- NCT07325773
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people
- Sponsor
- Marmara University
Whole Body Computed Tomography Imaging
Diagnostic Value of Whole-Body Computed Tomography (WBCT) Scores in Pediatric Trauma Patients
Pediatric trauma assessment is challenging due to difficulties in obtaining information, which increases the need for unnecessary imaging. Trauma-related injuries remain a significant cause of death in children.
- Trial name
- NCT06729528
- Testing
- The PePCI and ManTIS scores
- Where
- Turkey (Türkiye)
- Volunteers
- 684 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Lipedema, Exercise Therapy
Investigation of the Effects of High-Intensity Interval Exercise and Moderate-Intensity Continuous Exercise on Limb Volume, Functional Capacity, and Quality of Life in Patients With Lipedema
This randomized controlled clinical study aims to investigate and compare the effects of high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT), when combined with intermittent pneumatic…
- Conditions
- Lipedema, Exercise Therapy, High Intensity Interval Training
- Trial name
- NCT07319611
- Testing
- Intermittent Pneumatic Compression (IPC), Home-Based Walking Program, High-Intensity Interval Training (HIIT)
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Marmara University
Lipedema, Hypermobility Syndrome (Disorder)
Investigation of Medial Longitudinal Arch and Foot Function in Patients With Lipedema
Lipedema is a chronic adipose tissue disorder that commonly leads to joint laxity, hypermobility, and functional limitations, yet its impact on foot morphology has not been systematically examined.
- Conditions
- Lipedema, Hypermobility Syndrome (Disorder), Pes Planus, Joint Hypermobility
- Trial name
- NCT07294014
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Marmara University
Cervical Radiculopathy, Cervical Radicular Pain
Investigation of the Effects of Interlaminar Epidural Steroid Injection on Upper Extremity Proprioception in Patients With Chronic Cervical Radiculopathy
Cervical radiculopathy is a common condition caused by irritation or compression of cervical nerve roots, often leading to unilateral neuropathic pain and functional impairment.
- Conditions
- Cervical Radiculopathy, Cervical Radicular Pain, Proprioception
- Trial name
- NCT07307846
- Testing
- Interlaminar Epidural Steroid Injection (ILESI)
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Marmara University
Lateral Epicondylitis, Lateral Elbow Tendinopathy (Tennis Elbow)
Ultrasonographic Examination of Other Enthesitis Sites in Patients With Lateral Epicondylitis
Lateral epicondylitis (LE) is the tendinopathy of the common extensor tendon. Although exact etiology remains unclear, it is believed to be caused by overuse.
- Trial name
- NCT07314840
- Testing
- Madrid Sonographic Enthesitis Index
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Marmara University
Gestational Diabetes Mellitus (GDM)
Gestational Diabetes and Human Milk Composition Study
This study aims to compare hormone levels and milk composition in women with and without gestational diabetes through postpartum human milk and blood samples.
- Trial name
- NCT07051681
- Testing
- Individualized Medical Nutrition Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Marmara University
Endoscopic Submucosal Dissection, Target Controlled Infusion of Propofol
Comparison of the Effects of Target-Controlled Infusion Method and Manual Propofol Administration on Respiratory Function, Recovery, and Electroencephalogram in Endoscopic Submucosal Dissection Cases
Endoscopic submucosal dissection (ESD) has become widely used as a minimally invasive alternative for the resection of early-stage gastrointestinal neoplasms.
- Conditions
- Endoscopic Submucosal Dissection, Target Controlled Infusion of Propofol, Endoscopy Unit, Respiratory Complications
- Trial name
- NCT07305857
- Testing
- manuel propofol and target controlled infusion propofol
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Marmara University Pendik Training and Research Hospital
Evaluate the Fluorescence of Natural Tooth Following Dehydration
Effect of Dehydration on Dental Fluorescence
A cheek retractor will be placed to ensure consistent isolation throughout the procedure. Dehydration will be assessed at baseline, at the 5th minute, and at the 10th minute using three different evaluation techniques.
- Trial name
- NCT07295977
- Testing
- Digital photograph with Ashur plaque indicator, Digital photographs with the Led lights (365 nm), The QLF (Quantitative Light-Induced Fluorescence- 405 nm) images
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Marmara University
Geriatric Patient Care Improvement, EEG Data Analysis
Anesthetic Agent Titration With EEG Wave Analysis
Several studied shown that when general anesthesia is applied under BIS guidance, anesthetic doses are reduced. Additionally it has been found that the risk of postoperative delirium (POD) is reduced and postoperative recovery is…
- Trial name
- NCT07266727
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Marmara University
Acute Kidney Injury, Children
Renal Oxygen Saturation and Its Association With Acute Renal Injury
Peri-operative renal dysfunction is a major mortality and morbidity cause following cardiac and major vascular surgery. Although several intra-operative strategies are proposed for better outcomes, no effective and fast resulting…
- Conditions
- Acute Kidney Injury, Children, Cardiac Surgery
- Trial name
- NCT03608956
- Where
- Turkey (Türkiye)
- Sponsor
- Marmara University
Endodontic Diagnosis, Endodontic Diseases, Endodontic Treatment, Endodontic Decision-making
LLM Performance in Endodontic Diagnostics
The goal of this prospective observational study is to evaluate the ability of three large language models (ChatGPT-4o, Gemini Advanced, and Claude 3.7) to support diagnosis and treatment decision-making in adult patients…
- Trial name
- NCT07281066
- Testing
- AI-Based Diagnostic Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Marmara University
Ventilator Associated Pneumonia ( VAP)
Effect of Two Oral Care Methods on Oral Flora and VAP in Mechanically Ventilated Patients
This randomized controlled trial aims to evaluate the effect of two oral care methods on oral bacterial colonization and ventilator-associated pneumonia (VAP) in mechanically ventilated intensive care unit (ICU) patients.
- Trial name
- ORAVAP-RCT (NCT07283380)
- Testing
- Pediatric toothbrush, Sponge stick
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Marmara University