Clinical trials: sponsored by Menoufia University
Nonfunctioning Kidney, Renal Cell Carcinoma (RCC)
Laparoscopic Versus Open Nephrectomy : Clinical Effectivness and Cost Analysis
To evaluate and compare clinical effectiveness (operative time, blood loss, hospital stay, complications and etc) and cost analysis' between laparoscopic nephrectomy and open nephrectomy .
- Trial name
- NCT07461090
- Testing
- open or laparoscopic nephrectomy
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Major Depressive Disorder (MDD), SCHIZOPHRENIA 1 (Disorder)
Transcranial Direct Current Stimulation (tDCS) in Different Psychiatric Disorders
The goal of this clinical trial is to evaluate the efficacy and safety of transcranial direct current stimulation (tDCS) in reducing core symptoms of different psychiatric disorders using validated clinical scales.
- Conditions
- Major Depressive Disorder (MDD), SCHIZOPHRENIA 1 (Disorder), Obsessive-Compulsive Disorder, Generalized Anxiety Disorder
- Trial name
- Transcranial (NCT07452835)
- Testing
- tDCS Parameters
- Where
- Egypt
- Volunteers
- 320 people
- Sponsor
- Menoufia University
Post Operative Pain
Thoracic Epidural Analgesia With Bilateral Erector Spinae Plane Block in Radical Cystectomy Surgery
The aim of this study is to compare between Thoracic Epidural Analgesia (TEA) with ultrasound-guided bilateral erector spinae plane (ESP) block in radical cystectomy surgery for analgesic efficacy and hemodynamic effects
- Trial name
- TEAvsESB (NCT06324253)
- Testing
- bilateral Erector spine block,A dose of 30 ml 0.125% Bupivacaine will be injected., Thoracic epidural analgesia
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Menoufia University
Septic Shock
Comparison Between Using Cardiometry and IVC Collapsibility
Sepsis is a life-threatening condition caused by a dysregulated host response to infection, leading to organ dysfunction. Septic shock, a severe form of sepsis, is characterized by persistent hypotension and cellular/metabolic…
- Trial name
- NCT07411469
- Testing
- Cardiometry
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Menoufia University
Edentulous Jaw
Monolithic Zirconia Full-Arch Rehabilitation Using Digital Technology
20 edentulous patients presented for full-arch rehabilitation and was managed using a motion-integrated, fully digital workflow that combined the M-4 protocol in the maxilla with the All-on-4 concept in the mandible.
- Trial name
- NCT07369583
- Testing
- Motion-Integrated, Fully Digital Full-Arch Implant Rehabilitation Combining Maxillary M-4 and Mandibular All-on-4 Protocols with Monolithic Zirconia Prostheses
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Bone Loss
All-on-X Stackable Guides for Maxillary Terminal Dentition
This retrospective study will evaluate the clinical performance of maxillary All-on-X(full-arch implant-supported rehabilitation) implant rehabilitation using stackable guided surgery and immediate loading.
- Trial name
- NCT07353619
- Testing
- Maxillary All-on-X implant rehabilitation using a fully digital stackable guided surgery workflow with immediate loading.
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Menoufia University
Nocturnal Enuresis in Children, Desmopressin
Ginkgo Biloba vs Desmopressin in Treatment of Children With Monosymptomatic Nocturnal Enuresis
the efficacy of Ginkgo Biloba versus desmopressin in treatment of children with monosymptomatic nocturnal enuresis
- Conditions
- Nocturnal Enuresis in Children, Desmopressin, Monosymptomatic Nocturnal Enuresis
- Trial name
- NCT06771128
- Testing
- Ginkgo Biloba oral tablet, Desmopressin Acetate 0.2 mg Tablets
- Where
- Egypt
- Volunteers
- 398 people
- Sponsor
- Menoufia University
Renal Stones
Efficacy and Safety of Flexible Ureteroscopy Versus Percutaneous Nephrolithotomy in Management of Staghorn Stones
Percutaneous nephrolithotomy (PCNL) is considered the treatment of choice for management of large renal calculi larger than 2 cm based on the yearly updated European Association of Urology (EAU) guidelines.
- Trial name
- NCT07322471
- Testing
- Percutaneous nephrolithotomy, Flexible ureteroscopy
- Where
- Egypt
- Volunteers
- 138 people
- Sponsor
- Menoufia University
Prostate Cancer
Cognitive and Fusion Prostatic Biopsy
The goal of this study is to compare two different prostate biopsy techniques used to detect prostate cancer. These techniques are cognitive-targeted biopsy (CTB) and magnetic resonance imaging-ultrasound fusion-targeted…
- Trial name
- CTB-FTB (NCT07306741)
- Testing
- Cognitive-targeted prostate biopsy
- Where
- 2 sites in Egypt
- Volunteers
- 80 people
- Sponsor
- Menoufia University
Malocclusion
"Facially Driven Digital Full-Mouth Rehabilitation"
Participants with bite difficulties, smile dissatisfaction, and missing mandibular molars was rehabilitated using a fully digital, facially driven workflow.
- Trial name
- NCT07314034
- Testing
- Facially Driven, Fully Digital Full-Mouth Rehabilitation with Guided Implant Placement, TAD-Assisted Molar Intrusion, and Restorative Crowns/Veneers
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Menoufia University
Renal Calculi
Comparison of Lithotomy Versus Lateral Position in Retrograde Intrarenal Surgery for Lower Calyceal Stones Less Than 2 cm
Retrograde intrarenal surgery (RIRS) is an established minimally invasive treatment for renal stones, particularly for lower calyceal stones less than 2 cm, offering acceptable stone-free rates with low morbidity.
- Trial name
- NCT07310966
- Testing
- Lithotomy Position, Lateral position
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Menoufia University
Double J Stent
Microbiological Characteristics of Biofilm on Double J Ureteral Stents After Lithotripsy.
Indwelling Double J (DJ) ureteral stents are commonly used following lithotripsy to ensure adequate urinary drainage and prevent obstruction.
- Trial name
- NCT07301294
- Testing
- Linezolid (LZD), N-Acetyl Cysteine (NAC)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Menoufia University
Bone Loss
Crestal Bone Response to Narrow vs. Regular Tie-Base in Subcrestal Implants
This 24-month randomized clinical trial evaluates peri-implant marginal bone changes at subcrestal implants restored with narrow versus regular tie-base abutments.
- Trial name
- NCT07196228
- Testing
- Intervention Name (Arm 1): Narrow tie-base abutment Intervention Name (Arm 2): Regular tie-base abutment
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Bone Loss
Prospective Outcomes of Guided Equator Overdentures
This prospective clinical study evaluated the 3-year performance of mandibular implant-supported overdentures (IODs) placed using a fully guided static computer-assisted implant surgery (CAIS) protocol.
- Trial name
- NCT07196943
- Testing
- Fully guided static computer-assisted implant surgery (CAIS) for mandibular overdentures using Equator® attachments
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Menoufia University
Rhinosinusitis
Dexmedetomidine Infusion in Either Total Intravenous Anesthesia or Inhalational Anesthesia to Improve Surgical Field Visibility in Endoscopic Sinus Surgery
Dexmedetomidine Infusion in either Total Intravenous Anesthesia or Inhalational Anesthesia to Improve Surgical Field Visibility in Endoscopic Sinus Surgery
- Trial name
- NCT06866145
- Testing
- functional endoscopic sinus surgery, Dexmedetomidine
- Where
- 2 sites in Egypt
- Volunteers
- 50 people
- Sponsor
- Menoufia University
Postoperative Pain
Efficacy Of Ultrasound Guided External Oblique Intercostal Plane Block for Subcostal Nephrectomy
The patients will be randomly allocated into two equal groups using a computer program. Group A: will receive external oblique intercostal block after induction. Group B: will receive postoperative morphine per patient request.
- Trial name
- EOINB (NCT06056479)
- Testing
- external oblique intercostal block
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Menoufia University
Bone Loss in Jaw
Mandibular Overdentures vs All-on-4 With PEEK
This study compares long-term peri-implant outcomes between two mandibular full-arch rehabilitation approaches-four-implant-retained overdentures and All-on-4 fixed prostheses-when both are fabricated with polyetheretherketone…
- Trial name
- NCT07137533
- Testing
- Mandibular Four-Implant-Retained Overdenture (PEEK Framework); Mandibular All-on-4 Fixed Prosthesis (PEEK Framework)
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Menoufia University
Alveolar Osteitis
Assessment of Ozone Therapy for Management of Post-Extraction Localized Alveolar Osteitis
This clinical study investigates the effectiveness of ozone therapy in comparison to conventional treatment for alveolar osteitis (AO), a common painful complication following tooth extraction.
- Trial name
- NCT07106333
- Testing
- Topical Ozone Therapy, Irrigation with saline
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Bone Loss
Mandibular Overdentures Retained by Four Locator Attachments Versus Four-Implant Bar Attachments
This 10-year retrospective study investigates residual ridge changes in edentulous patients treated with mandibular overdentures (ODs) retained by either four Locator attachments or a four-implant bar system.
- Trial name
- NCT07093853
- Testing
- Four Locator Attachments, Four Bar Attachment System
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Menoufia University
Sedative Adverse Reaction
Morphine, Midazolam and Dexmedetomidine in the Management of Acute Cardiogenic Pulmonary Edema, Safety and Efficacy
Acute cardiogenic pulmonary edema is a stressful scenario with progressive respiratory failure that may lead to cardiorespiratory collapse within hours, or minutes unless therapeutic action is taken As the initial events in…
- Trial name
- NCT06653244
- Testing
- Injection
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Menoufia University