Clinical trials: sponsored by Menoufia University
Prostatic Hyperplasia, Prostate Enucleation
Bipolar Transurethral Enucleation Versus Resection in the Treatment of Benign Prostatic Hyperplasia: a Comparative Study
Benign prostatic hyperplasia (BPH) is a common chronic progressive disease resulting in the enlargement of the prostate gland and bladder outlet obstruction in aging men .
- Trial name
- NCT06294366
- Testing
- Bipolar Bowa device
- Where
- Egypt
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Intraoperative Bleeding
Comparison Between Atenolol,Propnalol and Ivabradine
The aim of this work is to compare atenolol, propranolol, and ivabradine as a premedication to achieve bloodless field anesthesia primarily controlling heart rate in lumbar spine surgery.
- Trial name
- NCT06670690
- Testing
- Atenolol 50 MG, Propranolol Pill, Ivabradine
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Bone Loss, Partial Edentulism Class 1
Short Implant Versus Crestal Standard Length Implant to Retain Class 1 Removable Partial Denture.
Objective: To report the implant survival rates, clinical, and radiographic outcomes of subcrestal short implant versus crestal standard length implant supported removable partial denture (RPD).
- Trial name
- NCT06666595
- Testing
- Titanium dental implant (Conical SPI, Vitronix, Italy), Medical device that interfaces with the jawbone to support a dental prosthesis.
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Pain, Postoperative
Ultrasound Guided Erector Spinae Block Versus Quadratus Lumborum Block For Postoperative Pain ReliefFollowing Laparoscopic Nephrectomy
The aim of this study is to assess the efficacy of Ultrasound guided erector spinae plane block versus quadratus lumborum block for postoperative analgesia in patient undergoing laparoscopic nephrectomy.
- Trial name
- NCT06655298
- Testing
- US guided block
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Menoufia University
Atelectasis, Postoperative
Lung Recruitment in Laparoscpic Surgery
The goal of this clinical trial study is to assess the effectiveness of different methods of lung recruitment maneuver on the incidence of atelectasis in adults undergoing laparoscopic cholecystectomy surgery using lung…
- Trial name
- NCT06221449
- Testing
- Positive end expiratory pressure
- Where
- Egypt
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Breast Cancer
This Study Investigates the Impact of Single Nucleotide Polymorphisms in Genes Involved in the Pharmacokinetics and Toxicity of Doxorubicin (DOX) in Egyptian Female Patients with Breast Cancer. It Also Aims to Explore the Association of Pretreatment Neutrophil to Lymphocyte Ratio to PCR
This study aims to investigate the effect of single nucleotide polymorphisms (SNPs) of genes involved in doxorubicin transport and metabolism on its pharmacokinetics and toxicity in Egyptian breast cancer patients.
- Trial name
- NCT06595758
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Menoufia University
Non-Small Cell Carcinoma of Lung, TNM Stage 4, Radiation Therapy
Radiotherapy to the Primary in Metastatic Non-small Cell Lung Cancer Patients
study the effect of radiotherapy to the primary lesion after first line systemic therapy in metastatic non-small cell lung cancer patients.
- Trial name
- NCT04776083
- Testing
- first line systemic therapy, 3D radiotherapy or IMRT
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Menoufia University
Labour Pain
Programed Intermittent Epidural Bolus Interval 90 (EI90) of 10 ml, 0.0625% Bupivacaine Plus 2 μg/mL Fentanyl
Multiple studies showed the numerous advantages of implementing programmed epidural bolus (PIEB) technique, where a fixed volume of local anesthetic is automatically administrated at a set time interval compared to the continuous…
- Trial name
- NCT05441085
- Testing
- programed intermittent epidural bolus interval 90 (EI90)
- Where
- 2 sites in Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Post Operative Pain
Sacral Erector Spinae Block for Pilonidal Sinus Surgery
The incidence of pilonidal sinus disease (PD) is estimated to be around 26/100,000 individuals mostly men.PD can cause the development of abscess or a draining sinus tract and that may lead to a loss of productive power and…
- Trial name
- NCT06577064
- Testing
- Sacral erector spinae plane block
- Where
- Egypt
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Post Operative Pain
External Oblique Intercostal Plane Block for Patients Undergoing Upper Abdominal Surgeries
Ithe study will evaluate the analgesic efficacy of external oblique intercostal block for patients undergoing upper abdominal surgeries
- Trial name
- EOINB (NCT06514417)
- Testing
- US-guided external oblique intercostal block
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Menoufia University
Implant Complication, Bone Loss
Survival Rate of 2 Implant-supported Short-span Fixed Partial Dentures
Implant supported superstructure is necessary for long term success and durability of the implant itself in terms of stresses distribution and fracture strength capability.1 Stresses falling on an implant are too much greater…
- Trial name
- NCT06447792
- Testing
- Loading protocol
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Menoufia University
Renal Cell Carcinoma
Oncological and Perioperative Outcomes of Laparoscopic Versus Robotic Partial Nephrectomy for Treatment of Renal Tumors.
partial nephrectomy offers lower renal function impairment and equivalent oncological survival outcomes compared with radical nephrectomy in those with T1 tumors.
- Trial name
- NCT06424080
- Testing
- laparoscopic partial nephrectomy, robotic partial nephrectomy
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Menoufia University
Prosthesis Survival, Bone Loss
Four-unit Implant Supported Fixed Partial Dentures Fabricated From Different Materials
Implant supported superstructure is necessary for long term success and durability of the implant itself in terms of stresses distribution and fracture strength capability.
- Trial name
- NCT06422260
- Testing
- Prosthesis superstructure
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Menoufia University
BPH, Intravesical Botox
Prostate Enucleation With Intravesical Botox Injections in Treating BPH and Bladder Overactivity
The aim of this study is to evaluate the effect of intravesical Botox injections on lower urinary tract symptoms (LUTS) when administered during Bipolar prostate enucleation surgery in patients with bladder outlet obstruction…
- Conditions
- BPH, Intravesical Botox, Bipolar Enucleation of the Prostate, Overactive Bladder
- Trial name
- BPH Botox (NCT05910983)
- Testing
- Bipolar enucleation of the prostate (BipolEP), Intravesical Botox injection
- Volunteers
- 100 people
- Sponsor
- Menoufia University
Inflammatory Response, Microbial Colonization
Microbial Adhesion and Biofilm Formation on Denture Base Materials
Polymethylmethacrylate (PMMA) has been the material of choice for fabricating complete dentures for more than 80 years now.(1,2) As a material it is easy to handle and can be easily repaired and polished.
- Conditions
- Inflammatory Response, Microbial Colonization, Denture Stomatitis
- Trial name
- NCT06395116
- Testing
- Denture base material
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Renal Stone
Comparison of High and Low Pulse Energy Dusting Protocols Using Holmium: YAG-laser in Flexible Ureteroscopy for Renal Stones Treatment
Rcompare high-energy versus low-energy laser settings in renal stone lithotripsy using low power machines) Holmium YAG 30 watts, examining their respective advantages, limitations, and overall efficacy.
- Trial name
- NCT06338137
- Testing
- Holmium Yag laser
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Menoufia University
Gouty Arthritis
The Impact of Metformin on the Outcome of Gouty Arthritis in a Cohort of Egyptian Gouty Patients.
Objective: To study the impact of metformin on the outcome of gouty arthritis in a cohort of Egyptian gouty patients, and to evaluate its effect on local joint inflammation, inflammatory cytokines (IL-1β and IL-6), and life…
- Trial name
- Mets in gout (NCT05332795)
- Testing
- Metformin
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Menoufia University
Cancer, Bladder, Cystostomy; Complications
Outcome of Perioperative Immune Enhancing Nutrition in Patients Undergoing Radical Cystectomy
The aim of this study is to evaluate the outcome of perioperative immune-nutrition with glutamine, arginine and fish oil in patients undergoing radical cystectomy as regards to enhancement of healing, increasing immunity and…
- Trial name
- NCT05822518
- Testing
- Neo-mune powder (otsuka pharmaceutical), Dipeptiven solution (Fresenius Kabi pharmaceutical)
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Menoufia University
Postoperative Pain
Efficacy of Erector Spinae Plane Block Analgesia After Off Pump Cardiac Surgery
In this study the investigators will investigate the efficacy of ESPB as a part of Enhanced recovery after surgery on postoperative analgesia and recovery criteria after off pump cardiac surgery.
- Trial name
- ESPB (NCT05769309)
- Testing
- Erector spinae block, Fentanyl
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Menoufia University
ERCP, Difficult CBD Cannulation
Comparison Between Different Techniques in Difficult CBD Cannulation
This study aims to compare the efficacy and outcomes between double guidewire technique (DGT), trans pancreatic sphincterotomy (TPS) as well as precut and fistulotomy techniques in ERCP in patients defined as having difficult…
- Trial name
- NCT06315647
- Testing
- DGT vs TPS vs Precut and fistulotomy in Difficult CBD cannulation
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Menoufia University