Clinical trials: sponsored by Montefiore Medical Center
Intubated ICU Patients
Shortened Preoperative Fasts in ICU
Randomized controlled trial assessing the safety and benefits of shortening preoperative fasts on intubated ICU patients undergoing tracheotomy.
- Trial name
- NCT03031379
- Testing
- shortened fast
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Montefiore Medical Center
Epilepsy
Stress Management Intervention for Living With Epilepsy (SMILE)
The study will examine whether a stress reduction intervention reduces the number of seizures in people with drug resistant epilepsy.
- Trial name
- SMILE (NCT01444183)
- Testing
- Progressive muscle relaxation
- Where
- 3 sites in United States
- Volunteers
- 95 people
- Sponsor
- Montefiore Medical Center
Migraine
Prochlorperazine vs Metoclopramide
Migraine headaches are a common reason for patients to present to an emergency department. We are comparing two different medications to see which one is better for patients who present ot an emergency room with a migraine…
- Trial name
- NCT00364806
- Testing
- Prochlorperazine, Metoclopramide
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Montefiore Medical Center
Chronic Rhinosinusitis w/o Nasal Polyps
DNA Microarray Analysis of Gene Expression in Chronic Rhinosinusitis
Analysis of differential gene expression in patients with chronic rhinosinusitis without polyps compared to unaffected patients. Correlation of abnormal gene expression with surgical outcomes.
- Trial name
- NCT01001819
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Montefiore Medical Center
Acute Pain
Protocolized vs Nonprotocolized Treatment of Adult ED Patients With Acute Severe Pain
Patients treated with protocolized pain management (1 mg of IV hydromorphone followed by an additional 1 mg IV hydromorphone if the patient wants more) will have better pain relief and no more adverse events than patients…
- Trial name
- NCT00627367
- Testing
- Hydromorphone, Nonprotocolized
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Autism
Trichuris Suis Ova in Autism Spectrum Disorders
The purpose of this study is to determine whether Trichuris Suis Ova (TSO) is safe and effective in treating adults with autism spectrum disorder
- Trial name
- TSO (NCT01040221)
- Testing
- Trichuris Suis Ova
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Montefiore Medical Center
Extubation Failures
Study to Evaluate Causes of Failure to Extubate
This is a prospective chart review of all extubations in the pediatric intensive care unit. Over a one year period all extubations in the unit are to be recorded on a designated form and standard variables charted and compared.
- Trial name
- RIPE (NCT01598246)
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Montefiore Medical Center
Arthroplasty, Replacement, Knee
The Combined Efficacy of Evicel and Tranexamic Acid on Total Knee Arthroplasty
Total knee arthroplasty is a surgical procedure that involves a significant amount of blood loss and it has always been the surgeons' goal to try to minimize blood loss.
- Trial name
- NCT02553122
- Testing
- Evicel, tourniquet
- Sponsor
- Montefiore Medical Center
Obesity, Morbid
Preoxygenation With Optiflow™ in Morbidly Obese Patients is Superior to Face Mask
Optiflow™ may provide an opportunity to prolong apnea time in the morbidly obese patient population. This study will examine whether Optiflow can do this, and compare the pre-oxygenation with Optiflow to the pre-oxygenation…
- Trial name
- NCT03009877
- Testing
- Optiflow F&P 850™ System, facemask, Rocuronium
- Volunteers
- healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Contraception
Effectiveness of a Patient Decision Aid in Immediate Postpartum Contraceptive Counseling
Effective physician-patient communication in postpartum contraceptive counseling is essential for patients to meet their contraceptive needs and reduce the risk of rapid repeat pregnancies.
- Trial name
- POCO (NCT03088397)
- Testing
- Patient Decision Aid, Website, Shared- Decision Making Counseling
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
End Stage Renal Failure on Dialysis
Anesthetic Technique for AV Fistulae Creation
This study is being done to compare the two anesthesia techniques which are commonly used in the formation of arteriovenous fistulas: local anesthesia and regional anesthesia.
- Trial name
- NCT01727557
- Testing
- regional anesthesia, local anesthesia
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Montefiore Medical Center
Cough Reflex Sensitivity
Antitussive Effect of a Naturally Flavored Syrup Containing Diphenhydramine, Compared With Dextromethorphan and Placebo
The purpose of this study is to evaluate the antitussive (cough-suppressing) effects of two liquid medications: a combination of diphenhydramine and phenylephrine in a naturally cocoa flavoring, and, dextromethorphan syrup…
- Trial name
- NCT02062710
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Montefiore Medical Center
Physical Activity, Obesity
Evaluation of CHAM JAM Increasing Physical Activity Levels in Students
The purpose of this study is to determine if the "Moving Smart" program, a daily 10-minute classroom-based exercise program, increases physical activity levels during the school day in Bronx elementary school students.
- Trial name
- NCT00556569
- Testing
- CHAM JAM
- Where
- United States
- Volunteers
- 10,098 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Asthma
A Community Health Worker Home Intervention to Improve Pediatric Asthma Outcomes
The investigators propose to test the hypothesis that a home-based asthma intervention, the Wee Wheezers program, delivered by the Community Health Workers and tailored to the needs of the investigators community, will improve…
- Trial name
- NCT01003340
- Testing
- Wee Wheezers
- Where
- United States
- Volunteers
- 188 people
- Sponsor
- Montefiore Medical Center
Pain
Comparative Efficacy of 4 Oral Analgesics
The purpose of this study is to perform a randomized, double blind 4-arm clinical trial of the comparative efficacy of 4 oral analgesics in the initial management of acute musculoskeletal extremity pain presenting to the ED.
- Trial name
- NCT02455518
- Testing
- Oxycodone/acetaminophen, Hydrocodone/acetaminophen, Codeine/acetaminophen
- Where
- United States
- Volunteers
- 416 people
- Sponsor
- Montefiore Medical Center
Pain, Acute
Acetaminophen IV vs Hydromorphone IV in the ED
The purpose of the current study is to compare the analgesic efficacy of intravenous acetaminophen and intravenous hydromorphone in the treatment of acute pain in the ED.
- Trial name
- NCT03107481
- Testing
- Acetaminophen, Hydromorphone
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Surgical Site Infection Following Cesarean Delivery
Comparison of Surgical Skin Preps During Cesarean Deliveries
In women that undergo non-emergency cesarean delivery, we are comparing the skin preparation solutions for best outcome of surgical site infection.
- Trial name
- NCT01870583
- Testing
- Iodine povidone, Chlorhexidine, Combination iodine and chlorhexidine
- Where
- 2 sites in United States
- Volunteers
- 1,404 people
- Sponsor
- Montefiore Medical Center
Ultrasound, Shock
The Impact of Point-of-Care Ultrasound
Point-of-care ultrasound (POCUS) has been found to be useful for aiding in the prediction of fluid responsiveness. It is unknown if trainees can effectively utilize this tool to improve their assessment of fluid responsiveness.
- Trial name
- NCT03276364
- Testing
- Ultrasound
- Volunteers
- 112 people
- Sponsor
- Montefiore Medical Center
Neuroepithelial Tumor, Solid Tumor
A Multi-Institutional Pilot Study of Allogeneic Hematopoietic Stem Cell Transplantation for Patients With Malignant Neuro-Epithelial and Other Solid Tumors
There is currently no standard treatment for patients with neuro-epithelial (brain) or other solid tumors in another part of the body who do not have adequate suitable autologous hematopoietic progenitor cells available and/or…
- Conditions
- Neuroepithelial Tumor, Solid Tumor, Allogeneic Hematopoietic Stem Cell Transplantation
- Trial name
- NCT02653196
- Testing
- Allogeneic hematopoietic stem cell transplant following thiotepa-based marrow ablative chemotherapy, Keratinocyte Growth Factor, Alemtuzumab
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Montefiore Medical Center
Molluscum Contagiosum
Safety and Efficacy Study of Topical Cantharidin for the Treatment of Molluscum Contagiosum
The purpose of this study is to determine if cantharidin is a safe and effective treatment for molluscum contagiosum in kids
- Trial name
- NCT02665260
- Testing
- Cantharidin, Gauze occlusion bandage
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center