Clinical trials: sponsored by National Taiwan University Hospital
Neurologic Dysfunction
Optic Nerve Sheath Diameter, Carotid Duplex and Transcranial Duplex as a Prognostic Factor
Optic nerve sheath diameter (ONSD) had been proved to be associated with increased intracranial pressure and can be used as one of the prognostic factors in cardiac arrest patients.
- Trial name
- NCT04510363
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Nursing
Effectiveness of Calgary Family Intervention Model in Caregivers
Effectiveness of Calgary family intervention model improving on uncertainty, family functioning, and resilience in caregivers of infants and toddlers undergoing open-heart surgery.Research hypothesis is The experimental group of…
- Trial name
- NCT06004622
- Testing
- Calgary Family Intervention Model
- Where
- Taiwan
- Volunteers
- 64 people
- Sponsor
- National Taiwan University Hospital
Paroxysmal Atrial Fibrillation (PAF), Atrial Flutter
Home Monitor for AA Burden Detection IIT in TWN
Primary Endpoint: Early detection rate in Atrial Arrhythmia (AA) burden Data transmission success rate for overall number of atrial burden collection during the monitoring period Secondary Endpoints: Atrial burden occurrence at…
- Trial name
- FF108 (NCT07572279)
- Where
- 4 sites in Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Bronchoscopy, Fasting ( 6H for Solid ; 2H for Clear Fluid )
Fasting Durations Before Bronchoscopy And The Discomfort Levels Of Patients
The goal of this clinical trial is to learn if patients feel more comfortable while being placed on contemporary fasting principle than on conventional fasting time during flexible bronchoscopy.
- Trial name
- NCT06779084
- Testing
- contemporary fasting principle, conventional fasting time
- Where
- Taiwan
- Volunteers
- 84 people
- Sponsor
- National Taiwan University Hospital
Critical Care Medicine, Emergency Medical Services
The TTM and ASM Trial
Sudden cardiac arrest (SCA) remains one of the major challenges in clinical care. Although improvements in resuscitation quality have increased the likelihood of return of spontaneous circulation (ROSC), most patients still fail…
- Conditions
- Critical Care Medicine, Emergency Medical Services, Cardiac Arrest (CA), Seizure
- Trial name
- NCT07835802
- Testing
- Prophylactic ASM, Hypothermic, Normothermic
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Out-Of-Hospital Cardiac Arrest
Systemic Evaluation of the Etiologies of Young Adults With Non-traumatic Out-of-hospital Cardiac Arrest
The goal of this observational study is to establish the protocol of systemic analysis of the causes of non-traumatic cardiac arrest in young patients.
- Trial name
- NCT06122337
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- National Taiwan University Hospital
Colonoscopy, Adenoma Detection Rate
Comparison of Adenoma Detection Rate in 3D vs. 2D Surveillance Colonoscopy
There is substantial evidence confirming that identifying and removing colorectal adenomas during colonoscopy helps prevent the development of colorectal cancer.
- Conditions
- Colonoscopy, Adenoma Detection Rate, Three Dimensional, Colon Polyps and Adenomas
- Trial name
- NCT07076966
- Testing
- 3D device
- Where
- 3 sites in Taiwan
- Volunteers
- 660 people
- Sponsor
- National Taiwan University Hospital
Adenoma Detection Rate, Colonoscopy
Comparison of the Performance Between Conventional Colonoscopy and 3D Colonoscopy in Positive Fecal Immunochemical Test Group
Background: Adenoma detection rate is one of the most quality indicator: an accumulating body of evidence has shown that detection and resection of pre-cancerous adenoma by colonoscopy could effectively prevent colorectal cancer…
- Conditions
- Adenoma Detection Rate, Colonoscopy, Three Dimensional, Fecal Immunochemical Test
- Trial name
- NCT06678477
- Testing
- 3D device
- Where
- 3 sites in Taiwan
- Volunteers
- 298 people
- Sponsor
- National Taiwan University Hospital
Total Hip Arthroplasty (THA), Magnetotherapy
Effects of Additional High-Intensity Pulsed Electromagnetic Field (HI-PEMF) Therapy on Pain and Physical Function After Total Hip Replacement
This study aims to verify whether high-intensity pulsed electromagnetic fields (HI-PEMF) can be effectively applied to postoperative total hip arthroplasty patients.
- Trial name
- NCT07564427
- Testing
- High-Intensity Pulsed Electromagnetic Field（HI-PEMF), Post Operative exercise
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
NSCLC Stage IV
Primary Tumor Resection With EGFR TKI for Stage IV NSCLC
Our project is going to enroll patients with stage IV NSCLC with EGFR mutation and evaluate whether primary tumor resection after receiving the afatinib can prolong survival.
- Trial name
- NCT05215548
- Testing
- therapeutic thoracic surgery, Afatinib
- Where
- 2 sites in Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Pompe Disease
Pompe Disease RWE Long-term Monitoring Program
Evaluate short- and long-term biomarker, motor function, respiratory function and safety with avalglucosidase alfa in IOPD and LOPD patients who switched from other ERT.
- Trial name
- NCT07834320
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
Parkinson Disease (PD)
Effects of Repetitive Transcranial Magnetic Stimulation (rTMS)-Primed Self-controlled Practice in People With Parkinson's Disease
Parkinson's disease (PD) is commonly associated with impaired motor learning and reduced motivation, both of which can negatively influence rehabilitation outcomes.
- Trial name
- NCT07832695
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), Physical therapy
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- National Taiwan University Hospital
Prostate Cancer
Predictive and Prognostic Markers for Treatment Outcomes in Prostate Cancer Patients
The study aims to identify potential urine marker metabolites as predictive or prognostic markers for treatment outcomes in patients with prostate cancer.
- Trial name
- NCT03237026
- Testing
- No intervention required
- Where
- Taiwan
- Volunteers
- 360 people
- Sponsor
- National Taiwan University Hospital
Atrial Fibrillation
Exercise Training to Atrial Fibrillation
To test the impacts of different exercise training programs to the cardiopulmonary function, muscle metabolism, and body mass composition
- Trial name
- ExAF (NCT04508478)
- Testing
- Aerobic training, Resistance training, Control physical exercise
- Where
- Taiwan
- Volunteers
- 8 people
- Sponsor
- National Taiwan University Hospital
Malignant Biliary Obstruction, Malignant Biliary Stricture
Endoscopic Ultrasound Guided Hepaticogastrostomy With or Without Antegrade Stenting for Palliation of Malignant Distal Biliary Obstruction: Randomized Controlled Trial
The purpose of this study is to compare the efficacy and safety between EUS-HGAS and EUS-HGS. We hypothesized that EUS-HGAS provides lower recurrent biliary obstruction (RBO) rate but with a comparable safety profile to EUS-HGS.
- Trial name
- EASE-MBO (NCT07832045)
- Testing
- HGAS, HGS
- Where
- Taiwan
- Volunteers
- 88 people
- Sponsor
- National Taiwan University Hospital
Esophageal Squamous Cell Carcinoma
Sacituzumab Govitecan for Advanced Esophageal Squamous Cell Carcinoma
The goal of this clinical trial is to investigate the efficacy and safety of sacituzumab govitecan in patients with advanced esophageal squamous cell carcinoma.
- Trial name
- SG-ESCC (NCT06329869)
- Testing
- Sacituzumab govitecan
- Where
- Taiwan
- Volunteers
- 35 people
- Sponsor
- National Taiwan University Hospital
Osteoarthritis (OA) of the Knee
Comparison of Effectiveness Between PL and PRP on Knee Osteoarthritis: a Prospective,Randomized,Placebo-controlled Trial
This study will focus on grade I to III knee osteoarthritis by randomized controlled trials which comparing the effectiveness between placebo, autologous platelet rich plasma and autologous platelet lysate injections.
- Trial name
- NCT03734900
- Testing
- Saline injection, PRP injection, PL injection
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- National Taiwan University Hospital
Terminal Cancer, Hospice
Exploring Indications and Practices of Administering Artificial Hydration to Terminal Cancer Patients in Taiwan
Background: The issue of artificial hydration for terminal cancer patients is a classic ethical dilemma in palliative care. It is a common practice especially when patients are incapable of oral intake; however, there is a lack…
- Conditions
- Terminal Cancer, Hospice, Palliative Medicine
- Trial name
- NCT06329856
- Testing
- Administering of artificial hydration
- Where
- Taiwan
- Volunteers
- 391 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
rTMS Stimulation, Autonomy
Repetitive Transcranial Magnetic Stimulation Primed Self-controlled Practice on Motor Learning
This study aims to investigate the additive effects of combining self-controlled practice with repetitive transcranial magnetic stimulation (rTMS) pretreatment on motivation enhancement and motor learning performance in healthy…
- Conditions
- rTMS Stimulation, Autonomy, Healthy Young Adults
- Trial name
- NCT07197346
- Testing
- rTMS - cTBS (Continuous Theta-Burst Stimulation), Self-controlled (autonomy), Yoked Practice
- Where
- Taiwan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Rare Diseases
DeciFace: Decipher the Influence of Ethnic Backgrounds on the Facial Dysmorphic Features of Rare Mendelian Disorders
There are more than 7000 known genetic disorders, and the number of affected is estimated to be about 6-10% of the population. Around 30 to 40% of genetic disorders have physical changes in the face and skull such as Down's…
- Trial name
- NCT05913843
- Testing
- Take photo
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital