Clinical trials: open to volunteers, sponsored by National Taiwan University Hospital
Osteoarthritis (OA) of the Knee
Comparison of Effectiveness Between PL and PRP on Knee Osteoarthritis: a Prospective,Randomized,Placebo-controlled Trial
This study will focus on grade I to III knee osteoarthritis by randomized controlled trials which comparing the effectiveness between placebo, autologous platelet rich plasma and autologous platelet lysate injections.
- Trial name
- NCT03734900
- Testing
- Saline injection, PRP injection, PL injection
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- National Taiwan University Hospital
Rare Diseases
DeciFace: Decipher the Influence of Ethnic Backgrounds on the Facial Dysmorphic Features of Rare Mendelian Disorders
There are more than 7000 known genetic disorders, and the number of affected is estimated to be about 6-10% of the population. Around 30 to 40% of genetic disorders have physical changes in the face and skull such as Down's…
- Trial name
- NCT05913843
- Testing
- Take photo
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Esophageal Squamous Cell Carcinoma
Sacituzumab Govitecan for Advanced Esophageal Squamous Cell Carcinoma
The goal of this clinical trial is to investigate the efficacy and safety of sacituzumab govitecan in patients with advanced esophageal squamous cell carcinoma.
- Trial name
- SG-ESCC (NCT06329869)
- Testing
- Sacituzumab govitecan
- Where
- Taiwan
- Volunteers
- 35 people
- Sponsor
- National Taiwan University Hospital
Malignant Biliary Obstruction, Malignant Biliary Stricture
Endoscopic Ultrasound Guided Hepaticogastrostomy With or Without Antegrade Stenting for Palliation of Malignant Distal Biliary Obstruction: Randomized Controlled Trial
The purpose of this study is to compare the efficacy and safety between EUS-HGAS and EUS-HGS. We hypothesized that EUS-HGAS provides lower recurrent biliary obstruction (RBO) rate but with a comparable safety profile to EUS-HGS.
- Trial name
- EASE-MBO (NCT07832045)
- Testing
- HGAS, HGS
- Where
- Taiwan
- Volunteers
- 88 people
- Sponsor
- National Taiwan University Hospital
Cardiac Arrest
Monitoring and Optimization of Cerebral Perfusion Pressure in Post-cardiac Arrest Patients: a Pilot Study
The goal of this study is to establish the ICP and CPP monitoring process and analyze the results in post-arrest patients, to validate the correlation between direct and non-invasive ICP monitoring indicators, to establish a…
- Trial name
- NCT06601842
- Testing
- ICP monitoring
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Extrapulmonary Small Cell Carcinoma and Neuroendocrine Carcinoma
Tarlatamab for Advanced Extrapulmonary Small Cell Carcinoma and Neuroendocrine Carcinoma (TAURUS)
Extrapulmonary small cell carcinoma (EPSCC) or neuroendocrine carcinoma (NEC) is a rare but fatal disease. The prognosis of patients with advanced EPSCC or NEC failed platinum-etoposide chemotherapy is poor with median overall…
- Trial name
- TAURUS (NCT06816394)
- Testing
- Tarlatamab
- Where
- Taiwan
- Volunteers
- 32 people
- Sponsor
- National Taiwan University Hospital
Parkinson Disease
Visuomotor Control in Parkinson Disease
Visuomotor processing is the ability to integrate visual information into motor plans and movement correction, which is highly required in daily activities such as writing and walking.
- Trial name
- NCT06918938
- Where
- Taiwan
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Metabolic Syndrome, Diabetes
Metabolic Syndrome and Prediabetes
This study aims to establish a cohort of individuals with metabolic syndrome and prediabetes to enable long-term follow-up of risk factors, disease progression, and the development of obesity-related complications.
- Trial name
- NCT07243821
- Where
- Taiwan
- Volunteers
- 2,000 people
- Sponsor
- National Taiwan University Hospital
Obesity and Obesity-related Medical Conditions
A Wearable Device and AI-Supported Diet and Exercise Intervention
This study implemented a personalized 6-month diet and exercise program to promote weight loss. Participants were recruited from outpatient clinics at the Department of Family Medicine, National Taiwan University Hospital.
- Trial name
- NCT06630663
- Testing
- A Wearable Device and AI-Supported Diet and Exercise intervention, standard care
- Where
- 2 sites in Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Obesity & Overweight, Weight Loss
A Prospective Cohort Study on Patient With Obesity Undergoing Weight Change
This prospective cohort study collected baseline data and followed up obese patients at their first visit to a weight loss clinic.
- Conditions
- Obesity & Overweight, Weight Loss, Metabolic Syndrome, Metabolic Dysfunction-Associated Steatohepatitis
- Trial name
- NCT07239167
- Where
- Taiwan
- Volunteers
- 500 people
- Sponsor
- National Taiwan University Hospital
Diabetes Mellitus Type 2
Patients With Type 2 Diabetes
Diabetes mellitus
- Trial name
- NCT07245082
- Where
- Taiwan
- Volunteers
- 2,000 people
- Sponsor
- National Taiwan University Hospital
Oncology Nurse, Psychological Support
The Impact of Multimedia Psychological Support Platform and Acceptance and Commitment Therapy Workshops of Oncology Nurses
Based on the high levels of emotional distress, burnout, and turnover intentions among clinical oncology nursing staff, this study will provide a multimedia "Mind-Body Support" Line platform and ACT workshop courses as…
- Conditions
- Oncology Nurse, Psychological Support, Acceptance and Commitment Therapy
- Trial name
- NCT06789926
- Testing
- Intervention Group
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Nursing, Artificial Intelligence (AI)
AI-Assisted Smart Interactive Healthcare Robot
To address workforce shortages and increasing workloads in nursing, technological solutions and AI-powered robots for ward navigation have been introduced. However, limitations remain in their application to clinical care.
- Conditions
- Nursing, Artificial Intelligence (AI), Deep Learning, Mechine Learning
- Trial name
- NCT06972043
- Testing
- Intervention Group
- Where
- Taiwan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Medical Visualization, Medical Illustration
Consensus And Norms for Medical Visualization Academic Standards Study - A Modified Delphi Study
The goal of this observational study (modified Delphi consensus study) is to establish an international expert consensus on professional standards for medical visualization in medical visualization experts from from around the…
- Conditions
- Medical Visualization, Medical Illustration, Consensus
- Trial name
- CANVAS (NCT07684703)
- Testing
- Delphi procedure
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Biliary Tract Neoplasms, Biliary Drainage
Suprapapillary Versus Transpapillary Plastic Stents for Unresectable Malignant Hilar Biliary Obstruction
Bile duct blockage caused by cancer near the liver hilum (where the bile ducts join) leads to jaundice and infection. The standard treatment is to place a plastic stent (a small tube) through an endoscope to drain the bile.
- Conditions
- Biliary Tract Neoplasms, Biliary Drainage, Malignant Biliary Obstruction, Obstructive Jaundice
- Trial name
- NCT07811791
- Testing
- Suprapapillary plastic stent placement, Transpapillary plastic stent placement
- Where
- 8 sites in Taiwan
- Volunteers
- 70 people
- Sponsor
- National Taiwan University Hospital
Lung Neoplasms, Non-Small Cell Lung Cancer
Osimertinib With or Without Primary Lung Tumor Resection for EGFR-Mutant Oligometastatic Non-Small Cell Lung Cancer
Osimertinib is a standard first-line treatment for patients with metastatic non-small cell lung cancer harboring an epidermal growth factor receptor exon 19 deletion or exon 21 L858R mutation.
- Trial name
- PTR-2 (NCT07738172)
- Testing
- Primary Tumor Resection, Osimertinib
- Where
- Taiwan
- Volunteers
- 154 people
- Sponsor
- National Taiwan University Hospital
Epiploic Appendagitis
Differentiating Right-sided Epiploic Appendagitis From Diverticulitis
This study will perform a retrospective analysis of adult patients who presented to the emergency department of National Taiwan University Hospital, Hsin-Chu and Yun-Lin Branches between January 2022 and December 2025 and were…
- Trial name
- NCT07794865
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Moyamoya Disease, Healthy
Cognitive-Motor Incorporated Training and Its Relations in Cerebrovascular Diseases With Cognitive and Motor Impairments
The following three-part proposal will explore the impact of applying motor-cognitive incorporated training (MCIT) in individuals with post-stroke cognitive impairment (PSCI) or Moyamoya disease (MMD), and examine the…
- Conditions
- Moyamoya Disease, Healthy, Stroke
- Trial name
- NCT07144930
- Testing
- MCIT program, Motor training program
- Where
- Taiwan
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Autism Spectrum Disorder
Exercise Interventions for Children With Autism Spectrum Disorder
The purpose of this clinical trial is to find out whether exergame and aerobic exercise can improve sleep, movement skills, thinking abilities, and brain activity in children with autism spectrum disorder (ASD).
- Trial name
- NCT07789457
- Testing
- Exergaming, Aerobic exercise, Conventional physical therapy
- Where
- Taiwan
- Volunteers
- 105 people
- Sponsor
- National Taiwan University Hospital
Breast Cancer
Developing and Testing the Efficacy of AI-Chatbot-Based
this study aims to develop the Calm-Mind-Recovery-Journey AI-Chatbot delivering BMS-MC therapy for breast cancer survivors and examine its feasibility, acceptability, safety, and preliminary effects of holistic well-being and…
- Trial name
- NCT07791368
- Testing
- AIAI-Chatbot CalmMindRecoveryJourney delivering BMS-MC therapy
- Where
- Taiwan
- Volunteers
- 68 people
- Sponsor
- National Taiwan University Hospital