Clinical trials: sponsored by Northwell Health
Healthy
Genotype and Phenotype Registry: Enrollment of Normal Control Subjects for Current and Future Research
Registry program for volunteers who are willing to serve as control subjects in future research studies.
- Trial name
- NCT00926042
- Where
- United States
- Volunteers
- 4,511 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Healthy, Chronic Disease
BioGene Bank Cohort Study for Approved Research Requests
The BioGene bank: Is a centralized collection of human blood samples along with de-identified (coded) health information, environmental factors, family disease histories and information from DNA.
- Trial name
- BGB (NCT02550171)
- Where
- United States
- Volunteers
- 7,056 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Alcohol-Related Disorders, Alcohol Use Disorders
Component Analysis for Motivational Interviewing
The purpose of this study is to investigate the critical components of motivational interviewing (MI), a psychotherapeutic intervention, in reducing heavy or problematic drinking.
- Conditions
- Alcohol-Related Disorders, Alcohol Use Disorders, Alcohol Drinking, Alcoholism
- Trial name
- NCT01642381
- Testing
- Full Motivational Interviewing ("FMI"), Spirit Only Motivational Interviewing ("SOMI")
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- Northwell Health
Schizophrenia
Comparison of Aripiprazole and Risperidone for the Treatment of People With First-Episode Psychosis
This 52 week long study evaluates the effectiveness of aripiprazole versus risperidone in treating people with first-episode schizophrenia.
- Trial name
- NCT00320671
- Testing
- Aripiprazole, Risperidone
- Where
- United States
- Volunteers
- 198 people
- Sponsor
- Northwell Health
Sperm DNA Impact on ART Outcomes
Impact of Sperm DNA Integrity on Artificial Reproductive Treatment (ART)
The purpose of this study is to establish a new criteria with which to judge the quality of sperm samples submitted for artificial reproductive treatments.
- Trial name
- NCT00875095
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Northwell Health
B-Cell Chronic Lymphocytic Leukemia
Hydroxychloroquine in Untreated B-CLL Patients
Eligible CLL patients who sign an informed consent will be started on hydroxychloroquine 400mg po daily for up to one year. They will be monitored for disease status as well as adverse reactions after two weeks and then every 4…
- Trial name
- NCT00771056
- Testing
- Hydroxychloroquine
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Northwell Health
Bronchiolitis
Single Dose of Furosemide to Improve Respiratory Distress in Moderate to Severe Bronchiolitis
The purpose of this study is to assess if administration of an early single dose of a diuretic (furosemide) to children with moderate to severe bronchiolitis can reduce extravascular lung water in an effort to reduce respiratory…
- Trial name
- NCT02469597
- Testing
- Furosemide
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Northwell Health
Status Asthmaticus
Pleth Variability and Asthma Severity in Children
Research has shown that pleth variability can be used to assess asthma severity in children with status asthmaticus. The investigators would like to use an FDA-cleared monitor (Masimo Radical 7) which measures Pleth Variability…
- Trial name
- NCT02302261
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Northwell Health
Cancer, Thromboembolism
Anticoagulation and Inferior Vena Cava Filters in Cancer Patients With a Venous Thromboembolism
The development of clots is a potentially deadly complication in many cancer patients. The current optimal treatment is unknown. Evidence supporting the effectiveness of the use of Inferior Vena Caval Filters is lacking.
- Trial name
- NCT00423683
- Testing
- Arixtra alone, Arixtra + filter
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Northwell Health
Head Trauma
Pain in Traumatic Brain Injury - Basile, MD
The observation through a chart review of persistent pain on neuro psychological functioning and how it applies to the community integration with patients that had suffered traumatic brain injury.
- Trial name
- NCT01136486
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Northwell Health
Status Asthmaticus
A Prospective Trial of BiPAP Administration vs. Non-positive Pressure Therapy for Pediatric Status Asthmaticus
Though BiPAP is an increasingly common tool used by pediatric critical care physicians and there is promising data suggesting a role for BiPAP in the management of status asthmaticus, more information is needed to more…
- Trial name
- NCT02539420
- Testing
- BiPAP treatment
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwell Health
Asthma, Obesity
The Effect of Montelukast on Asthma Control in Overweight/Obese Atopic Asthmatics
Background: In recent years, the prevalence of both asthma and obesity has risen dramatically among children and adolescents in the United States. Given the concurrent rise in the two epidemics, there may be an underlying link.
- Conditions
- Asthma, Obesity, Inflammation
- Trial name
- NCT01329939
- Testing
- Montelukast
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Northwell Health
Glioblastoma Multiforme, Anaplastic Astrocytoma
Oral Tarceva Study for Recurrent/Residual Glioblastoma Multiforme and Anaplastic Astrocytoma
This study will offer a safe treatment for patients with relapsing recurring glioblastoma (GBM) or anaplastic astrocytoma (AA). The trial will test the hypothesis that Erlotinib (Tarceva, OSI-774) can be safely used up to a dose…
- Trial name
- NCT00301418
- Testing
- Erlotinib
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Northwell Health
High Risk MC4R Genotype, Low Risk MC4R Genotype
1/2-MC4R Genotype and Pediatric Antipsychotic Drug- Induced Weight Gain
We will conduct a 12-week, randomized open label study, comparing usual care (UC) antipsychotic treatment (aripiprazole, quetiapine, risperidone) with ziprasidone (ZIP) in children and adolescents aged 13-18 years old.
- Conditions
- High Risk MC4R Genotype, Low Risk MC4R Genotype, One Week or Less Antipsychotic Lifetime Exposure
- Trial name
- NCT01844700
- Testing
- Ziprasidone, aripiprazole, quetiapine, or risperidone
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Northwell Health
SLE
3,3'-Diindolylmethane in Patients With Systemic Lupus Erythematosus
This is a single center study of patients with inactive or mild SLE being performed to determine the safety, tolerability, and pharmacodynamics of DIM.
- Trial name
- NCT02483624
- Testing
- BR-DIM
- Volunteers
- 6 people
- Sponsor
- Northwell Health
Asthma
Study of T-Regulatory Cells in Asthma
To study whether the immune response as directed by regulatory T cells is different between obese asthmatics, normal weight asthmatics and healthy controls.
- Trial name
- NCT02574351
- Testing
- blood draw, breathing test
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Retinal Disease
Erythrocyte Ghost Mediated Retinal Diagnosis
Instead of the usual procedure of injecting ICG dye directly into an arm vein, now the dye can be placed inside of RBCs. When a small volume of the RBC's with the dye is injected into a person's arm, the individual RBCs can be…
- Trial name
- EGMRetinalDx (NCT02445001)
- Testing
- ICG loaded erythrocytes
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwell Health
Hypertension, Pulmonary
The Role of Echocardiographic Contrast (Optison) in Enhancing Tricuspid Regurgitation Spectral Doppler Signals
The investigators aim to correlate noninvasive pulmonary artery systolic pressure (PASP) measurements obtained with and without echocardiographic contrast (Optison) during transthoracic echocardiography (TTE) with those obtained…
- Trial name
- NCT02560116
- Where
- United States
- Sponsor
- Northwell Health
Asthma
Study of Budesonide as an Addition to Standard Therapy in Adult Asthmatics in the Emergency Room.
To determine whether adding nebulized inhaled steroids to the standard care of acutely ill ED patients with refractory acute asthma helps improve forced expiratory volume at one second (FEV1) and decrease the need for…
- Trial name
- NCT00588406
- Testing
- Budesonide, albuterol, Ipratropium bromide
- Where
- 3 sites in United States
- Volunteers
- 95 people
- Sponsor
- Northwell Health
Morbid Obesity
Weight Loss & Comorbidity Resolution With LAGB Alone vs. LAGB With Gastric Plication
The purpose of this research study is to evaluate whether combining laparoscopic adjustable gastric band (AKA: lap-band surgery, LAGB) and laparoscopic gastric plication (making tucks in the large curve of the stomach with…
- Trial name
- NCT01703546
- Testing
- LAGB & LGCP
- Where
- 2 sites in United States
- Volunteers
- 420 people
- Sponsor
- Northwell Health