Clinical trials: sponsored by Odense University Hospital
Older Patients, Medication Review
Telephone Contact Between Hospital and General Practitioner About Medication Review for Older Patients
In this trial, the feasibility of cooperation between clinical pharmacists and physicians by conducting a telephone follow-up conversation between the hospital geriatrician, the general practitioner and the clinical pharmacist is…
- Conditions
- Older Patients, Medication Review, Cross-sectional Communication
- Trial name
- NCT03369652
- Testing
- Medication review
- Where
- 2 sites in Denmark
- Volunteers
- 232 people
- Sponsor
- Odense University Hospital
Diabetic Macular Oedema
Aflibercept anD navigateD vErsus coNvensional Laser in Diabetic macUlar edeMa
Diabetic macular edema (DME) in diabetic retinopathy (DR) is the leading cause of visual impairment among the 300,000 Danish patients with diabetes (DM) and will in time affect 29% of patients.
- Trial name
- ADDENDUM (NCT02554747)
- Testing
- Navigated laser, Conventional laser
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Odense University Hospital
Renal Cell Carcinoma, Renal Tumor
Non-Invasive Diagnostics of Small Renal Masses
NiSAR is a Ph.D. study and consists of three substudies. Renal cancer is one of the most deadly urologic malignancies and accounts for 900 new cases and 300 deaths per year.
- Trial name
- NISar (NCT03667885)
- Testing
- Blood sample, urine sample, Multi planar MRI
- Where
- Denmark
- Volunteers
- 160 people
- Sponsor
- Odense University Hospital
Peyronie Disease
Low-Intensity Extracorporeal Shockwave Therapy and Vacuum Erectile Device as a Treatment for Peyronies Disease.
Aim The primary aim is to examine whether LI-ESWT and vacuum erectile device (VED) followed by manipulation exercises has beneficial effect on PD patients compared to a placebo group.
- Trial name
- NCT03530540
- Testing
- low-intensity extracorporeal shockwave therapy, Penile pump
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Odense University Hospital
Head and Neck Cancer, Radiation Therapy Complication
The Use of Chewing Gum for Xerostomia and Hyposalivation After Radiotherapy for Oral and Oropharyngeal Tumors
This study evaluates the possible benefits of a tasteless and sugar free chewing gum as a salivary stimulant for head and neck cancer patients treated with curative intended radiotherapy.
- Conditions
- Head and Neck Cancer, Radiation Therapy Complication, Xerostomia, Hyposalivation
- Trial name
- NCT03302676
- Testing
- Chewing gum
- Where
- Denmark
- Volunteers
- 109 people
- Sponsor
- Odense University Hospital
Postoperative Hemorrhage
Lateral Occlusion of Uterine Artery in Total Laparoscopic Hysterectomy
Laparoscopic hysterectomy is associated with complications in form of infections and subsequently dehiscence of the vault. This is a serious complication.
- Trial name
- NCT02709460
- Testing
- Lateral occlusion, Cervical occlusion
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Odense University Hospital
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Three-dimensional Measurements of Diabetic Foot Ulcers
Diabetic foot ulcers constitute an increasing health problem in Denmark concurrent with an ageing population and an increase in diabetes prevalence. Diabetic foot ulcers belong to the most serious and costly complications.
- Conditions
- Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Diabetes Complications, Diabetic Foot
- Trial name
- NCT02423850
- Testing
- 3D Wound Assessment Monitor (WAM) camera
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Odense University Hospital
Rheumatoid Arthritis
Fibrocytes in Early and Longstanding Rheumatoid Arthritis
This study will focus on a rare cell population called fibrocytes in peripheral blood and synovial tissue in Rheumatoid Arthritis (RA). One group of patients with early RA and one group with long-standing RA.
- Trial name
- NCT02652299
- Testing
- Synovial biopsy
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Odense University Hospital
Subarachnoid Hemorrhage, Hypoxia Ischemia, Cerebral
Combined Intracerebral and Jugular Bulb Microdialysis
The first aim of this study is to investigate the frequency and severity of a specific pathological metabolic pattern, mitochondrial dysfunction, of the brain in comatose patients under neurocritical care.
- Conditions
- Subarachnoid Hemorrhage, Hypoxia Ischemia, Cerebral, TBI, Meningitis
- Trial name
- NCT03314779
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Odense University Hospital
Lyme Neuroborreliosis
An Intervention in a Primary Healthcare Setting to Reduce Lyme Neuroborreliosis Treatment Delay
This study evaluates the effect of written and oral information in a primary health care setting on 1) patients referred to specialised examination for Lyme neuroborreliosis, 2) delay from patient symptom debut to treatment for…
- Trial name
- NBdelay (NCT03820999)
- Testing
- Oral and written information on tick-bites and Lyme disease
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Odense University Hospital
Proliferative Diabetic Retinopathy
The Individually Marked Panretinal lasEr phoTokoagUlation for Proliferative Diabetic Retinopathy Study - DETECT
The purpose of this study is to determine the threshold level of proliferative diabetic retinopathy progression and regression after standard panretinal photocoagulation.
- Trial name
- IMPETUS-D (NCT02157350)
- Testing
- Panretinal laser photocoagulation
- Where
- Denmark
- Volunteers
- 65 people
- Sponsor
- Odense University Hospital
HPV in Testis Tissue
HPV as a Possible Cause of Azoospermia
Azoospermia is found in 5-20% of all men suffering from infertility, and in more than 20% azoospermia remains unexplained. The investigators suggest, that HPV may be an etiological factor in azoospermia and reduced sperm…
- Trial name
- NCT02329275
- Testing
- Testicular biopsy
- Where
- Denmark
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Cancer
Geriatric and Oncologic Assessment Before Treatment
In a randomized controlled trial, the investigators wish to investigate, if oncologic treatment decision based on G8 screening followed by geriatric assessment and subsequent MDT, if needed, in older frail patients with…
- Trial name
- GOAT (NCT02671994)
- Testing
- G8 screening, Geriatric assessment
- Where
- Denmark
- Volunteers
- 114 people
- Sponsor
- Odense University Hospital
Type 2 Diabetes Mellitus
Dose-response Effect of Pine Nut Oil as a Dual FFA1 and FFA4 Agonist on Glucose Tolerance in Healthy Humans.
Several free fatty acids receptors (FFARs) have been discovered. These have been implicated in metabolic processes and inflammation.
- Trial name
- NCT03305367
- Testing
- Hydrolyzed pine nut oil
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Type2 Diabetes Mellitus, Obesity
FFAR Agonist on Incretins, Insulin, Lipids and Inflammation
Several free fatty acids receptors (FFARs) have been discovered. These have been implicated in metabolic processes and inflammation.
- Trial name
- NCT03062592
- Testing
- Pine nut oil
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Pain, Physical Activity
Influence of Expectations on Change in Pain Perception After a 3 Min Wallsquat Exercise.
The purpose of this study is to investigate how expectations induced by information given prior to exercise influence the magnitude of exercise-induced hypoalgesia after a 3 min wallsquat exercise in healthy subjects.
- Trial name
- NCT03678662
- Testing
- Hypoalgesia expectation, Hyperalgesia expectation, Neutral
- Where
- Denmark
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Prostate Cancer
Choline PET/CT vs. Dual Time Point FDG PET/CT in Prostate Cancer
Prostate cancer is currently the leading newly diagnosed cancer in the industrialized world. Treatment of prostate cancer is highly dependent on the stage of the disease.
- Trial name
- NCT02232724
- Testing
- Choline PET/CT and Dual time point FDG PET/CT
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Odense University Hospital
Pneumonia
Mechanical Insufflation-Exsufflation Compared With CPAP in Patients Admitted to an Intermediate Care Unit With Pneumonia
Pneumonia, an infection in the lower airways, is a common cause of hospital contacts and a leading cause of death from infections worldwide.
- Trial name
- CoughAssist (NCT03714321)
- Testing
- Mechanical insufflation-exsufflation (MIE)
- Volunteers
- 30 people
- Sponsor
- Odense University Hospital
Coronary Artery Disease, Coronary Disease
Fractional Flow Reserve Versus Angiography Randomization for Graft Optimization Trial
The FARGO trial is a prospective, randomized (1:1), multicenter study. The aim of the study is to assess the importance of fractional flow reserve (FFR) assessment prior to coronary artery bypass grafting (CABG) with respect to…
- Conditions
- Coronary Artery Disease, Coronary Disease, Myocardial Ischemia, Arteriosclerosis
- Trial name
- FARGO (NCT02477371)
- Testing
- Fractional flow reserve-guided CABG, Angiography-guided CABG
- Where
- 3 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Odense University Hospital
Hand Related Injuries
The Effect of Activity-based Training in Patients With Hand-related Injuries Grouped Using Sense of Coherence Scores
Background Patients with the same type of hand injury often reach different functional levels. Therefore, it is necessary to investigate what kind of rehabilitation is most efficient for each individual patient.
- Trial name
- NCT02098564
- Testing
- Joint mobility exercises hand therapy, activity-based hand therapy
- Where
- Denmark
- Volunteers
- 504 people
- Sponsor
- Odense University Hospital