Clinical trials: sponsored by Oregon Health and Science University
Parent-Child Relations, Preterm Birth
Bilateral Infant Stimulation Study
This study will investigate stress that parents of children admitted to the neonatal intensive care unit (NICU) experience. Investigation of a novel intervention of using bilateral alternating stimulation to reduce parental…
- Conditions
- Parent-Child Relations, Preterm Birth, Stress Reaction, Hospitalism in Children
- Trial name
- BLISS (NCT06353243)
- Testing
- Bilateral alternating stimulation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Oregon Health and Science University
School Readiness
Clinic-Based School Readiness Coaching
The goal of this clinical trial is to examine how a clinic-based school readiness coaching session conducted by a community health worker for parents of 3-5-year-olds affects children's School Readiness (SR) skills and parents…
- Trial name
- NCT06390215
- Testing
- School Readiness Coaching Intervention
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Depression, Suicide
Reaching Out to Distressed Medical Residents, Fellows and Faculty
The purpose of this study is to study whether distressed medical residents, fellows, and faculty health professionals benefit from completing online an anonymous and interactive screening of stress, depression, substance use, and…
- Trial name
- NCT02010866
- Testing
- counseling
- Where
- United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Spine Fusion
Steroids After Spine Fusion Surgery
This trial studies how well low-dose postoperative corticosteroids (FDA approved) affect patient outcomes (patient reported outcomes, pain medication use, length of stay, major complications, and time to first bowel movement)…
- Trial name
- NCT04568837
- Testing
- Prednisone 20 Mg
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Hypertension
Evaluating Control of Hypertension - Effect of Social Determinants
This study evaluates the impact of a large-scale, national expansion of Medicaid on hypertension incidence, screening, treatment, and management.
- Trial name
- ECHOES (NCT03545763)
- Testing
- Medicaid Expansion
- Where
- United States
- Volunteers
- 1,939,783 people
- Sponsor
- Oregon Health and Science University
Pediatric, Critical Illness
Sleep After Pediatric Critical Illness
This study tests a pilot educational sleep intervention for children after critical care hospitalization.
- Conditions
- Pediatric, Critical Illness, Sleep Disturbance
- Trial name
- NCT05879640
- Testing
- Sleep education
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Oregon Health and Science University
Overdose, Drug
Reducing Overdose After Release From Incarceration
The primary objective of the ROAR project is to evaluate an Oregon Department of Corrections (ODOC) pilot program that combines the use of extended-release naltrexone (XR-NTX) and Certified Recovery Mentors pre-release with…
- Trial name
- ROAR (NCT03902821)
- Testing
- XR-NTX and Certified Recovery Mentor
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Oregon Health and Science University
Atrial Fibrillation, Atrial Flutter
The Z Stitch Early Bed Rest Assessment Study
The goal of this study is to understand the effects of early mobilization after a Z stitch procedure in patients undergoing certain heart-related treatments.
- Conditions
- Atrial Fibrillation, Atrial Flutter, Supraventricular Tachycardia, Syncope
- Trial name
- ZEBRA (NCT06087497)
- Testing
- Early mobilization
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Oregon Health and Science University
MRI
VAPORHCS/OHSU J: MRI and Devices
This is a database study of clinically indicated MRIs on patients with permanent pacemakers and implantable cardioverter defibrillators.
- Trial name
- NCT03915015
- Testing
- MRI
- Where
- 2 sites in United States
- Volunteers
- 10,000 people
- Sponsor
- Oregon Health and Science University
Lead Extraction Procedures
Pacemaker and Defibrillator Lead Extraction Registry
Implanted cardiac devices are commonly used to treat a wide variety of heart diseases, including arrhythmias, cardiac resynchronization in select heart failure patients, and life threatening heart rhythms.
- Trial name
- NCT03847025
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Oregon Health and Science University
Neurocognitive Disorders, Anesthesia
Total Intravenous Versus Inhalational Anesthesia- A Geriatric Anesthesia Study
Traditionally, general anesthesia is maintained with inhalational anesthesia (GAS), but there is a gap in knowledge regarding whether intravenous anesthesia (IV) can prevent deleterious postoperative outcomes in the geriatric…
- Conditions
- Neurocognitive Disorders, Anesthesia, Post-operative Delirium, Post-operative Cognitive Dysfunction
- Trial name
- TIVA GAS (NCT06036095)
- Testing
- Sevoflurane, Propofol
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Intellectual Disability, Speech and Language Disorder
Early Augmentative and Alternative Communication (AAC) Intervention Delivered Via Hybrid Telehealth
The goal of this mixed methods study aims to develop and pilot test an augmentative and alternative communication (AAC) intervention for toddlers with intellectual and developmental disabilities (IDD) and their families.
- Trial name
- NCT05743439
- Testing
- Early Augmentative and Alternative Communication (AAC) Intervention
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Contraception
Pharmacists Expand Access to Reproductive heaLthcare
Prospective cohort study of women presenting to initiate hormonal contraception, prescribed by a clinician or pharmacist. Women will be followed for one year to assess contraceptive continuation and unintended pregnancy rates, as…
- Trial name
- PEARL (NCT03830567)
- Testing
- Pharmacist prescription, Clinician prescription
- Where
- United States
- Volunteers
- 471 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Type1diabetes
Automated Insulin Delivery vs. Injections: Sleep Impact in Pediatric Type 1 Diabetes
The purpose of the study is to learn about the effect of insulin pumps on sleep in pediatric patients with type 1 diabetes and their caregivers.
- Trial name
- NCT06347783
- Testing
- Insulin pump
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Oregon Health and Science University
Trauma, Surgery
Lovenox 30 mg Twice Daily (BID) Versus 40 mg Once Daily (QD)
The risk of developing a blood clot occurs in up to 60% of all critical care patients. Many times enoxaparin (or Lovenox) is given to patients who are at a higher risk of developing clots in their legs or lungs.
- Conditions
- Trauma, Surgery, Deep Vein Thrombosis (DVT), Thromboembolic Events
- Trial name
- NCT02342444
- Testing
- Enoxaparin Sodium Injection 30 mg BID, Enoxaparin Sodium Injection 40 mg QD
- Where
- United States
- Volunteers
- 606 people
- Sponsor
- Oregon Health and Science University
Circadian Rhythm, Cardiometabolic Health
Circadian Time Restricted Eating
The goal of this study is to learn more about how the time in which participants consume their meals relative to their personalized circadian rhythm influences their overall cardiometabolic health and weight.
- Conditions
- Circadian Rhythm, Cardiometabolic Health, Weight Loss, Cardiovascular Health
- Trial name
- CTRE (NCT05628012)
- Testing
- Circadian Based Time Restricted Eating
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Sleep Deprivation, Obesity
Sleep and Metabolism
The goal of this study is to uncover sleep and circadian mechanisms contributing to adverse metabolic health. The protocol is a 21 day (7 outpatient days, 14 inpatient days) mechanistic randomized-crossover study designed to…
- Conditions
- Sleep Deprivation, Obesity, Glucose Intolerance, Weight Gain
- Trial name
- SAM (NCT05775627)
- Testing
- Sleep Restriction
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Health Services for Transgender Persons, Transgender Persons
Comparing Subcutaneous Testosterone to Intramuscular Testosterone in Gender Affirming Care of Transgender Male Adolescents
The trial studies the efficacy of subcutaneous (SQ) testosterone compared to intramuscular (IM) testosterone therapy during the first 6 months of pubertal induction in transgender male adolescents.
- Trial name
- NCT03864913
- Testing
- Testosterone injection, PedsQL questionnarie, Masculinizing effects questionnaire
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Carbohydrate Intolerance
Impact of Two Dietary Interventions on Simple Carbohydrate Intolerance
In this project we want to assess impact of dietary fructose as a simple sugar intolerance on abdominal pain and compare a low FODMAP diet versus an added sugar elimination diet effectiveness on symptoms but also impact on…
- Trial name
- NCT06057376
- Testing
- Low-FODMAP diet group (LFD), Low Sugar diet group (LAS)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Oregon Health and Science University
Traumatic Brain Injury
Pilot Study of Whole Blood Transfusion for Trauma Brain Injury (TBI)
Our goal is to perform a pilot, single center study to evaluate the efficacy of whole blood (WB) in subjects with TBI, intracranial hemorrhage, and anemia compared to blood component therapy.
- Trial name
- NCT06184828
- Testing
- Whole blood transfusion, Blood components transfusion
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University