Clinical trials: sponsored by Oslo University Hospital
Hypertension, Resistant to Conventional Therapy
Effect of Renal Sympathetic Denervation on Resistant Hypertension and Cardiovascular Hemodynamic in Comparison to Intensive Medical Therapy Utilizing Impedance Cardiography
The purpose of this study is to demonstrate that Renal Sympathetic Denervation (RDN) improves the control of blood pressure (BP) in patients with treatment-resistant hypertension, as compared to intensive medical therapy (IMT)…
- Trial name
- OsloRDN (NCT01673516)
- Testing
- The SymplicityTM Renal Denervation System, The HOTMAN® System
- Where
- Norway
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Hypothermia
Accuracy of Non-invasive Temperature Measurement in Deep Hypothermia
In pre-hospital care, there are few non-invasive thermometers that are proved both robust and accurate. The aim of this study is to investigate the accuracy of a certain ear-canal based thermometer on patients undergoing thoracic…
- Trial name
- NCT02009059
- Testing
- Non-invasive temperature in hypothermia
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Oslo University Hospital
Multiple Organ Failure, Critical Care
The Pharmacokinetics of Fentanyl in Intensive Care Patients
This study is part of a project intended to develop guidelines to optimise the dosing of fentanyl in intensive care patients. This study will focus on determining: Whether the pharmacokinetics of fentanyl change during the ICU…
- Conditions
- Multiple Organ Failure, Critical Care, Intensive Care
- Trial name
- FENTANYL06 (NCT02587273)
- Testing
- Fentanyl
- Where
- Norway
- Volunteers
- 150 people
- Sponsor
- Oslo University Hospital
Fatigue
Improving Symptom Management for Cancer Patients and Their Caregivers Through Internet
Being diagnosed and treated for cancer is usually associated with severe side effects and symptoms. Cancer patients can have difficulty to manage the symptoms as a result of treatment which may cause i) an interruption or…
- Trial name
- NCT01867723
- Testing
- Internet communication application
- Where
- Norway
- Volunteers
- 560 people
- Sponsor
- Oslo University Hospital
Coronary Heart Disease
After Eighty Study
The rationale of the present clinical trial is to study whether an invasive strategy in clinical stable patients over 80 years with NSTEMI/UAP may improve rates of death, reinfarction, stroke, need of urgent revascularisation…
- Trial name
- NCT01255540
- Where
- Norway
- Volunteers
- 492 people
- Sponsor
- Oslo University Hospital
Colorectal Neoplasms
Geriatric Intervention in Frail Elderly Patients With Colorectal Cancer
This is a randomized, controlled trial on frail elderly patients (aged 65+) with colorectal cancer. The patients will be randomized into two groups. The control group will receive standard surgical treatment.
- Trial name
- NCT01321658
- Testing
- Geriatric intervention
- Where
- Norway
- Volunteers
- 122 people
- Sponsor
- Oslo University Hospital
Breast Cancer
Effects of Internet Support for Cancer Patients
Being diagnosed and treated for cancer is usually associated with severe physical symptoms, impaired functional status, complex emotional, psychosocial and existential issues and substantial worries.
- Trial name
- WebChoice 2 (NCT00971009)
- Testing
- OPPC service, WebChoice IHCA
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- Oslo University Hospital
Glioblastoma, Brain Tumor
Safe Study of Dendritic Cell (DC) Based Therapy Targeting Tumor Stem Cells in Glioblastoma
The study induces an immune response towards the stem-cell like part of glioblastomas in combination with standard therapy. The aim is to define and characterize the feasibility, potential adverse effects of such therapy and…
- Trial name
- NCT00846456
- Testing
- Dendritic cell vaccine with mRNA from tumor stem cells
- Volunteers
- 20 people
- Sponsor
- Oslo University Hospital
Mental Illness
Cognitive Behaviour Therapy and Cognitive Training in Work Rehabilitation for Persons With Severe Mental Illness
This study will compare the effects of cognitive behaviour therapy (CBT) and cognitive training in work rehabilitation of patients with severe mental illness (psychoses).
- Trial name
- NCT01139502
- Testing
- Work rehabilitation based on the cognitive therapeutical model, Work rehabilitation with the addition of cognitive training
- Where
- Norway
- Volunteers
- 140 people
- Sponsor
- Oslo University Hospital
Osteoporosis
Active Rehabilitation in Osteoporotic Patients
The main objective of this study is to target risk factors for falling, such as improved quadriceps muscle strength,balance and bone mineral density (BMD), to reduce the risk of osteoporotic fractures.
- Trial name
- ARO (NCT01357278)
- Testing
- Rehabilitation and patient education
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- Oslo University Hospital
Critically Ill, Acute Renal Failure
2012_PharmacoCRRT-study:Pharmacokinetics of Anti-infectives in Critically Ill Patients in Need of Continuous Renal Replacement Therapy (CRRT)
The main purpose of the study is to examine if changes in pharmacokinetics of important antiinfectives in Critically Ill patients in need of continuous renal replacement therapy (CRRT), causes inadequate concentrations in plasma.
- Conditions
- Critically Ill, Acute Renal Failure, Acute Kidney Injury
- Trial name
- PharmacoCRRT (NCT01582360)
- Where
- Norway
- Volunteers
- 640 people
- Sponsor
- Oslo University Hospital
Rds, Pulmonary Hypertension
High Flow Ventilation With Volume Guarantee
The trial is a pilot study performed in the NICU's at Oslo University Hospital and Haukeland University Hospital preparing a multi-center randomized, controlled unblinded cross-over study, comparing high frequency ventilation…
- Conditions
- Rds, Pulmonary Hypertension, Meconium Aspiration Syndrome
- Trial name
- NCT02571231
- Testing
- HFV + and - VG
- Volunteers
- 15 people
- Sponsor
- Oslo University Hospital
Postoperative Pain
Ultrasound-guided Quadratus Lumborum Block for Postoperative Pain Relief After Cesarean Delivery
The Quadratus Lumborum (QL) Block is an ultrasound-guided technique described by Rafael Blanco in 2007. The nerves to the lower abdominal wall can be anesthetized by injecting local anesthetics close to the anterior border of the…
- Trial name
- NCT02036749
- Testing
- nerve block
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Oslo University Hospital
Prostate Cancer
Clinical Study Evaluating Targeted Biopsies and Cytological Imprints in Prostate Cancer
The investigators will evaluate the accuracy of performing cytological imprints of targeted biopsies when diagnosing prostate cancer.
- Trial name
- NCT01745718
- Testing
- Cytological imprints
- Where
- Norway
- Sponsor
- Oslo University Hospital
Unspecified Disorder of Bone Density and Structure
Mg Induced Changes From Day 0 to Day 28 on Serum and Urine Bone Metabolic Parameters in 70 y Old Females (no 50).
Calcium and vitamin D substitution has for a long time been used to improve osteoporosis.The main storage place for magnesium is in the bone.
- Trial name
- parathormon (NCT02549521)
- Testing
- Oral magnesium substitution
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Breast Reconstruction, Skin Perfusion
Microcirculation of the Abdominal Skin After Deep Inferior Epigastric Artery Perforator Flap Procedure
The purpose of this study was to perform a quantitative perfusion study of the undermined abdominal skin in deep inferior epigastric artery perforator flap breast reconstruction patients in order to obtain more knowledge on…
- Trial name
- NCT02481284
- Testing
- Laser Doppler perfusion imaging
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Oslo University Hospital
Chlamydia Trachomatis Infection, Chlamydial Urethritis
Mecillinam for Treatment of Genital Chlamydia Infection
The mainstay of treating both symptomatic and asymptomatic genital Chlamydia trachomatis infection has been macrolide antibiotics in the form of azithromycin, and alternatively tetracycline antibiotics in the form of doxycycline.
- Trial name
- MecillinamCT (NCT02083276)
- Testing
- Pivmecillinamhydrochlorid
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Oslo University Hospital
Dupuytrens Contracture
Prospective Randomized Trial Between Needle Fasciotomy and Xiapex for Dupuytrens Contracture
The purpose of this study is to investigate whether percutaneous needle fasciotomy is as effective for treating Dupuytrens contracture as Xiapex.
- Trial name
- PNFvsxiapex (NCT02476461)
- Testing
- xiapex, percutaneous needle fasciotomy
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Oslo University Hospital
Psoriasis
Psoriasis and Climate Therapy- Effect of Motivational Follow- up Calls on Clinical and Health Economic Parameters
The aim of this study is to evaluate clinical and health economic parameters in relation to individual motivational counseling by phone.
- Trial name
- NCT01352780
- Testing
- Motivational interviewing
- Where
- 2 sites in Norway
- Volunteers
- 169 people
- Sponsor
- Oslo University Hospital
Deep Vein Thrombosis
Catheter-Directed Venous Thrombolysis in Acute Iliofemoral Vein Thrombosis
Deep vein thrombosis (DVT) is a severe disease, and conventional treatment with low molecular weight heparin (LMWH) and warfarin is associated with some degree of long-term sequelae, i.e. post-thrombotic syndrome (PTS).
- Trial name
- CaVenT (NCT00251771)
- Testing
- catheter-directed venous thrombolysis
- Where
- Norway
- Volunteers
- 209 people
- Sponsor
- Oslo University Hospital