Clinical trials: sponsored by Oslo University Hospital
Health Care Providers, Stress
Digital Stress Management Intervention for Health Care Providers
The purpose with this study is to test if the app-based stress management program StressProffen, can be of interest and support for stress management among health care providers.
- Conditions
- Health Care Providers, Stress, Psychological
- Trial name
- NCT05607758
- Testing
- StressProffen©™
- Where
- Norway
- Volunteers
- 117 people
- Sponsor
- Oslo University Hospital
Celiac Disease
Teriflunomide vs. Placebo During Gluten Challenge in Celiac Disease
The investigators will see if the drug teriflunomide (which is in use in other immune disorder (multiple sclerosis)) can inhibit the immune activation in celiac disease patients during a 3 day gluten challenge.
- Trial name
- NCT04806737
- Testing
- Teriflunomide Oral Tablet
- Where
- Norway
- Volunteers
- 15 people
- Sponsor
- Oslo University Hospital
Aortic Dissection, Factor X Inhibition
The Effect of the CytoSorb® Filter to Remove Anticoagulants From the Circulation During Emergency Surgery for Aortic Dissection
The direct oral anticoagulants (DOACs) and particularly the FXa inhibitors are a concern in patients presenting with type A aortic dissection as this may contribute to severe bleeding complications.
- Trial name
- Citron (NCT05235178)
- Where
- Norway
- Volunteers
- 11 people
- Sponsor
- Oslo University Hospital
Suicide Attempt
Patients Admitted to ICU After a Suicide Attempt
The goal of this study is to increase the knowledge on the experience and symptom profile to suicide attempters admitted to an ICU.
- Trial name
- SA_ICU (NCT06966505)
- Where
- Norway
- Volunteers
- 86 people
- Sponsor
- Oslo University Hospital
Myotonic Dystrophy 1
Symptoms and Outcome Measures for Upper- Limb Function in Myotonic Dystrophy Type 1
Myotonic Dystrophy type 1 (DM1) is a multisystem disease that causes muscle weakness and myotonia. As a result upper limb function might become impaired.
- Trial name
- SOUL-DM1 (NCT05006924)
- Where
- 3 sites in Norway
- Volunteers
- 89 people
- Sponsor
- Oslo University Hospital
Locally Advanced Pancreatic Cancer, Borderline Resectable Pancreatic Cancer
A New Clinical Pathway for Personalized Management of Borderline Resectable and Locally Advanced Pancreatic Cancer
NORPACT-3 is a nationwide, Norwegian single arm prospective study that evaluates the resectability rates and survival in patients with borderline resectable and locally advanced pancreatic cancer who received primary…
- Conditions
- Locally Advanced Pancreatic Cancer, Borderline Resectable Pancreatic Cancer, Pancreatectomy, Chemotherapy Effect
- Trial name
- NORPACT-3 (NCT06944587)
- Testing
- Chemotherapy, Radiology, Pancreatectomy
- Where
- 5 sites in Norway
- Volunteers
- 400 people
- Sponsor
- Oslo University Hospital
Drug Effect
A Pilot Study for Optimizing Meropenem Administration in the ICU
Can antibiotic drugs be administered faster and make acceptable serum concentrations if we give short but multiple infusions compared to long and fewer infusions? In this study we will compare giving meropenem 1 gram 6 times…
- Trial name
- MER6 (NCT05578586)
- Testing
- Meropenem 1000 mg
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Oslo University Hospital
Harmful Stereotypies, Feeding Difficulties
Stereotypic Behaviors and Feeding Difficulties in Adults With Developmental Disabilities
Adults with developmental disabilities (DD) and autism represent a vulnerable demographic that transitions into adulthood with diverse etiologies, exhibiting a significantly higher prevalence of various challenging behaviors.
- Trial name
- NCT06920615
- Testing
- Fading and chaining combined with differential reinforcement, Differential reinforcement of high rate, Response interruption with redirection
- Where
- Norway
- Volunteers
- 8 people
- Sponsor
- Oslo University Hospital
Toxic Alcohol Poisoning
Fomepizole Dosing During Continuous Renal Replacement Therapy (CRRT)
The project is a prospective observation study of patients with suspected or confirmed toxic alcohol poisoning treated with fomepizole and continuous renal replacement therapy (CRRT)
- Trial name
- NCT04649138
- Where
- Norway
- Volunteers
- 11 people
- Sponsor
- Oslo University Hospital
Prostate Cancer
Focal Prostate Ablation Versus Radical Prostatectomy
This study aims to compare the treatment results of HIFU and Radical prostatectomy.
- Trial name
- FARP (NCT03668652)
- Testing
- Focal HIFU treatment using Focal One (EDAP TMS) or TULSA-PRO (Profound Medical), Radical prostatectomy
- Where
- Norway
- Volunteers
- 213 people
- Sponsor
- Oslo University Hospital
Venous Malformation, Pain
A Study of Enalapril in Treatment of Venous Malformations
The goal of this clinical trial is to explore if enalapril can be used to treat painful venous malformations. The main question it aims to answer are: Can enalapril reduce pain and volume of the malformation and increase quality…
- Conditions
- Venous Malformation, Pain, Quality of Life, Vascular Malformation
- Trial name
- EVA (NCT06788314)
- Testing
- Enalapril
- Where
- Norway
- Volunteers
- 12 people
- Sponsor
- Oslo University Hospital
Plantar Fascitis, Gastrocnemius Tightness
Treatment of Gastrocnemius Tightness and Subsequent Chronic Plantar Fasciitis with Botulinum Toxin a
This prospective clinical cohort study will follow 40 patients who recieve botulinum toxin A treatment for proximal medial gastrocnemius tightness with subsequent Chronic Plantar Fasciitis for two years.
- Trial name
- PLATOX (NCT05218785)
- Testing
- Botox
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Oslo University Hospital
Diabetes Mellitus, Claudication, Intermittent
Additional Hyperbaric Oxygen After Lower Extremity Amputation
This study evaluates the effect of additional hyperbaric oxygen therapy after lower extremity amputation. The patients will be randomized after amputation to either a treatment group receiving hyperbaric oxygen therapy, or…
- Conditions
- Diabetes Mellitus, Claudication, Intermittent, Critical Limb Ischemia, Osteomyelitis
- Trial name
- AHOLEA (NCT03594344)
- Testing
- Hyperbaric oxygen therapy
- Where
- 2 sites in Norway
- Volunteers
- 120 people
- Sponsor
- Oslo University Hospital
Rare Malignant Neoplasm
Precision Cancer Therapy in Rare Cancers
Some rare cancers are hard-to-treat and patients have a poor prognosis. It is known that some of these patients have targetable molecular alterations, and some benefit from targeted drugs.
- Trial name
- MATRIX-Rare (NCT06119789)
- Testing
- Imatinib, Trametinib, Dabrafenib
- Where
- Norway
- Volunteers
- 96 people
- Sponsor
- Oslo University Hospital
Ischemia Limb, Blood Circulation Disorder
Ischemia Detection During Development of Acute Compartment Syndrome
This is an open, observational, prospective, descriptive, single-centre study including 60 patients. The study is designed to investigate if IscAlert sensor system can be used for reliable and continuous tissue carbon dioxide…
- Conditions
- Ischemia Limb, Blood Circulation Disorder, Carbon Dioxide, Biosensing Techniques
- Trial name
- IDEA (NCT06079255)
- Testing
- IscAlert sensor(s) in patient with risk of acute compartment syndrome
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Oslo University Hospital
Psychosis
Virtual Reality and Artificial Intelligence in Treatment for Patients With Psychosis
Virtual Reality (VR) has gained momentum in the treatment of various mental health conditions. Despite its potential and emphasis on better use of technology in healthcare strategies, VR therapy for severe mental illness remains…
- Trial name
- RecoVRy (NCT06728241)
- Testing
- RecoVRy, VR Games
- Where
- 2 sites in Norway
- Volunteers
- 150 people
- Sponsor
- Oslo University Hospital
Uncontrolled Hypertension
An Interventional Multidisciplinary Approach to Individualize Blood Pressure Treatment
The aim of the study is to investigate and explore the most important aspects of drug-adherence in the treatment of hypertension in order to improve treatment and blood pressure control, implying that new knowledge will reduce…
- Trial name
- IDA (NCT03209154)
- Testing
- Therapeutic drug monitoring, Home blood pressure monitoring
- Where
- Norway
- Volunteers
- 1,000 people
- Sponsor
- Oslo University Hospital
Surgery
Arthroscopic Surgical Procedures vs Sham Surgery for Patients With Femoroacetabular Impingement and/or Labral Tears.
The primary aim of this study is to determine the efficacy of hip arthroscopic surgery compared to a sham surgery (diagnostic arthroscopy only) for patients with symptomatic and radiological findings related to impingement (FAI)…
- Trial name
- HIPARTI (NCT02692807)
- Testing
- Arthroscopic surgical procedures
- Where
- 2 sites in Australia, Norway
- Volunteers
- 140 people
- Sponsor
- Oslo University Hospital
Post Traumatic Stress Disorder
Intensiv Inpatient Trauma Treatment. A Pilotstudy.
Aim of the study: Post traumatic stress disorder (PTSD) is a psychiatric illness that can develop after having experienced traumatic, often life treathening, events.
- Trial name
- ITBD (NCT05342480)
- Testing
- EMDR and PE combined treatment
- Where
- Norway
- Volunteers
- 18 people
- Sponsor
- Oslo University Hospital
Sepsis Syndrome
Diagnostic Accuracy in Sepsis
The sepsis syndrome has recently been more stringently defined as "a life-threatening organ dysfunction caused by a dysregulated host response to infection".
- Trial name
- NCT03956043
- Where
- Norway
- Volunteers
- 1,989 people
- Sponsor
- Oslo University Hospital