Clinical trials: completed, sponsored by Peking Union Medical College Hospital
Breast Cancer
Trastuzumab Administered Concurrently or Sequentially to Anthracycline-containing Adjuvant Regimen for Breast Cancer
Most of the published data support the preferential use of an anthracycline-containing adjuvant regimen for individuals with HER2-positive tumors.
- Trial name
- NCT01413828
- Testing
- concurrent, sequential
- Where
- China
- Volunteers
- 201 people
- Sponsor
- Peking Union Medical College Hospital
Breast Cancer
DA Versus DAC as Postoperative Adjuvant Treatment for Early-stage Breast Cancer
Our study is a prospective, non-inferior, randomized phase II clinical trial, to compare the efficacy and safety profiles of DA versus DAC as adjuvant chemotherapy regimens for early-stage breast cancer patients.
- Trial name
- NCT02838225
- Testing
- Docetaxel, Doxorubicin, Docetaxel, Doxorubicin, Cyclophosphamide
- Volunteers
- 300 people
- Sponsor
- Peking Union Medical College Hospital
Septic Shock
The Effect of Lactate Clearance Oriented Haemodynamic Therapy on the Outcome of Patients With Septic Shock
The purpose of this study is to explore and assess possible outcome benefits of lactate clearance>30% vs ScvO2 ≥70% in 6 hours as the protocol goal that evaluated adequacy of during early resuscitation of septic shock through a…
- Trial name
- NCT02566460
- Testing
- Resuscitation
- Volunteers
- 360 people
- Sponsor
- Peking Union Medical College Hospital
Smoking, Vascular System Injuries
Melatonin in Smoke-induced Vascular Injury
The main purpose of this study was to evaluate the effects of melatonin in the regulation of the vascular injury in smokers through population-based, randomized, double-blind, placebo-controlled trial.
- Trial name
- NCT02591238
- Testing
- non-smoker oral melatonin, smoker oral melatonin
- Where
- China
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Pain, Postoperative
Safety and Efficacy of Cocktail Periarticular Injection in Simultaneous Total Knee Arthroplasty
We investigated the safety and efficacy of the bilateral periarticular cocktail injection at a reduced dosage in patients undergoing simultaneous bilateral total knee arthroplasty.
- Trial name
- NCT02270437
- Testing
- ropivacaine, fentanyl, adrenaline
- Where
- China
- Volunteers
- 55 people
- Sponsor
- Peking Union Medical College Hospital
Pain, Postoperative
Parecoxib for Pain Management After Total Knee Arthroplasty and Total Hip Arthroplasty
Evaluated the effect of perioperative parecoxib administration on postoperative pain, analgesic use, function recovery, inflammatory response and bleeding risk.
- Trial name
- NCT02272660
- Testing
- Parecoxib sodium, Normal saline injection
- Where
- China
- Volunteers
- 74 people
- Sponsor
- Peking Union Medical College Hospital
Pancreatic Neuroendocrine Tumors
Comparative Study of Robotic, Laparoscopic and Open Surgery for Enucleation of Benign Pancreatic Neoplasms
To determine the efficacy and safety of robotic, laparoscopic and open surgery for enucleation of benign pancreatic neuroendocrine tumors
- Trial name
- NCT02125929
- Testing
- Robotic surgery, Laparoscopic surgery, Open surgery
- Where
- China
- Volunteers
- 156 people
- Sponsor
- Peking Union Medical College Hospital
Knee Arthritis Osteoarthritis
Clinical Observation and MRI Influence of Acupuncture on Knee Osteoarthritis
To observe the therapeutic effect of acupuncture on osteoarthritis(OA) and its efficacy on cartilage restoration,acupuncture and physiotherapy treatment were respectively given to two random groups.
- Trial name
- NCT02446756
- Testing
- acupuncture, physiotherapy
- Volunteers
- 50 people
- Sponsor
- Peking Union Medical College Hospital
Pulse Oximetry Plethymographic Waveform, Area Under Curve
The Normal Reference Values of Pulse Oximetry Plethymographic Waveform Parameters
The purpose of this study is to determine the normal reference values of pulse oximetry plethymographic waveform parameters in Chinese population.
- Conditions
- Pulse Oximetry Plethymographic Waveform, Area Under Curve, Amplitude
- Trial name
- NCT02292420
- Where
- China
- Volunteers
- 1,019 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Osteogenesis Imperfecta
Efficacy and Safety of Alendronate in Chinese Children or Adolescents With Osteogenesis Imperfecta
Alendronate should be considered as an alternative therapy of osteogenesis imperfecta (OI) because it significantly increased areal bone mineral density (BMD) and its Z score, decreased fracture incidence, inhibited bone…
- Trial name
- NCT02303873
- Testing
- Alendronate
- Volunteers
- 99 people
- Sponsor
- Peking Union Medical College Hospital
Cerebral Embolic Damage
MMP-9 Monitoring Particulate Cerebral Embolisation
1. In carotid endarterectomy(CEA) surgery, the dynamic changes of plasma MMP9 concentration cross CEA will be identified. 2. And the part of patients suffered particulate cerebral embolic injury, their MMP9 level will increase in…
- Trial name
- MMP9MPCE (NCT02109120)
- Testing
- vein blood collection
- Where
- China
- Volunteers
- 48 people
- Sponsor
- Peking Union Medical College Hospital
Osteoarthritis
Evaluation of Short-term Effects of Tourniquet Use in Different Ways During Total Knee Arthroplasty
To study the short-term effects of tourniquet use in different ways in total knee arthroplasty,60 patients were randomly divided into 2 groups (30 cases/group): group A using the tourniquet throughout the operation, and group B…
- Trial name
- NCT02102581
- Testing
- short time tourniquet
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking Union Medical College Hospital
Overactive Bladder, Postmenopausal Disorder
Effectiveness and Safety Study of Solifenacin Succinate and Solifenacin Succinate + Estrogen to Treat OAB in Postmenopausal Women
This study is a multi-site, randomized, opened and parallel-controlled clinical study. The patients up to the inclusion criteria are randomly treated with Solifenacin Succinate Tablets (5mg/d) or Solifenacin Succinate Tablets…
- Conditions
- Overactive Bladder, Postmenopausal Disorder, Urination Disorders
- Trial name
- OAB (NCT01833663)
- Testing
- Solifenacin Succinate Tablets, Estrogen
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking Union Medical College Hospital
Subclinical Hypothyroidism
Thyroid Screening Protocol During Pregnancy: a Multi-center Prospective Controlled Study
Estimate the proper thyroid screening method during pregnancy. Evaluate if maternal subclinical hypothyroidism treatment during pregnancy result in improved pregnancy outcome and cognitive function in the children.
- Trial name
- NCT01838031
- Testing
- thyroid screening
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Peking Union Medical College Hospital
Breast Cancer
Ultrasound and Mammography for Screening Breast Cancer in Chinese Women
Early detection of breast cancer through screening has been a common practice in the United States and several European countries for decades.It is effective in reducing the mortality of breast cancer and improving the…
- Trial name
- NCT01880853
- Testing
- mammography, ultrasound, mammography and ultrasound
- Where
- 14 sites in China
- Volunteers
- 47,709 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Arthritis, Rheumatoid
Efficacy and Safety of Tripterygium Wilfordii in Patients With Rheumatoid Arthritis
Evaluation of oral T2 (chloroform/methanol extract of Tripterygium wilfordii Hook F) in the treatment of RA patients with clinical efficacy and safety.Open-labeled, randomized, prospective multi-center clinical trial.
- Trial name
- TRIFRA (NCT01613079)
- Testing
- Tripterygium wilfordii Hook F, Methotrexate
- Where
- China
- Volunteers
- 201 people
- Sponsor
- Peking Union Medical College Hospital
Hemifacial Spasm
A Multicenter, Observational Study to Evaluate Clinical Manifestation, Diagnosis and Treatment of Primary Hemifacial Spasm in Chinese Patients
To determine the clinical manifestation, diagnosis and treatment options of primary hemifacial spasm in Chinese outpatient subjects
- Trial name
- NCT01728428
- Where
- China
- Volunteers
- 1,003 people
- Sponsor
- Peking Union Medical College Hospital
Stomach Neoplasms
Enhanced Magnifying Endoscopy for Diagnosis of Early Gastric Cancer
When performing screening endoscopy, small focal gastric lesions are frequently encountered. Novel techniques in endoscopy, such as magnifying endoscopy (ME) with narrow-band imaging (NBI) and chromoendoscopy with acetic…
- Trial name
- NCT01617876
- Where
- China
- Volunteers
- 282 people
- Sponsor
- Peking Union Medical College Hospital
Postmenopausal Endometrium
Compare the Difference of P4 Concentration in Serum and Endometrium After Vaginal and IM P Administration
Crinone is a micronized progesterone gel which is administrated via vaginal route and targeted drug delivery to uterine (first uterine pass effect) with lower serum concentration.
- Trial name
- NCT01057511
- Testing
- Crinone 8%, Progesterone
- Where
- China
- Volunteers
- 51 people
- Sponsor
- Peking Union Medical College Hospital
Healthy
Pharmacokinetics and Pharmacodynamics of Higenamine in Chinese Healthy Subjects
The purpose of this study is to assess the pharmacokinetics and pharmacodynamics of higenamine in healthy Chinese subjects
- Trial name
- NCT01451229
- Testing
- higenamine
- Where
- China
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital