Clinical trials: sponsored by Peking University
Prostate Cancer
The Value of Dual-parametric Magnetic Resonance Combined With Regional Saturation Biopsy in Patients With Suspected Prostate Cancer
The aim of this study was to investigate the value of dual-parameter magnetic resonance imaging(bpMRI) combined with regional saturation biopsy in the diagnosis of prostate cancer by means of a prospective randomized controlled…
- Trial name
- NCT06824259
- Testing
- Follow up if MRI is negative, Systematic biopsy if MRI is negative
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Peking University First Hospital
Prostate Cancer, Robot-Assisted Laparoscopic Radical Prostatectomy
Enhanced Recovery After Surgery (ERAS) Pathway in Patients Undergoing Robot-Assisted Laparoscopic Radical Prostatectomy
Prostate cancer ranks second among all malignances in men and has become a significant threat to men's health. Robot-assisted laparoscopic radical prostatectomy (RARP) has become a standard treatment for prostate cancer.
- Conditions
- Prostate Cancer, Robot-Assisted Laparoscopic Radical Prostatectomy, Enhanced Recovery After Surgery (ERAS) Protocol, Prehabilitation
- Trial name
- NCT05576766
- Testing
- Routine care, ERAS management pathway
- Where
- China
- Volunteers
- 54 people
- Sponsor
- Peking University First Hospital
Prostate Cancer, Oligometastatic Prostate Cancer
Comprehensive Versus Primary Tumor Radiotherapy in Oligometastatic Prostate Cancer
This study is a multicenter, randomized controlled phase III clinical trial (PROLONG-3) designed to evaluate the survival benefit of comprehensive radiotherapy combined with primary tumor radiotherapy versus primary tumor…
- Trial name
- PROLONG-3 (NCT07015138)
- Testing
- TRT, NTRT
- Where
- 3 sites in China
- Volunteers
- 390 people
- Sponsor
- Peking University First Hospital
Gestatiaonl Diabetes Mellitus
Impact of Antepartum Breast Milk Expression on Breastfeeding Rates in Patients With Gestational Diabetes Mellitus
This study proposes a prospective randomized controlled clinical trial involving primiparous women diagnosed with gestational diabetes mellitus (GDM) carrying singleton pregnancies.
- Trial name
- NCT07128433
- Testing
- milk expression
- Volunteers
- 212 people
- Sponsor
- Peking University First Hospital
Chronic Obstructive Pulmonary Disease, COPD
Shared Medical Appointment for COPD Patients (SMA-COPD)
The goal of this clinical trial is to evaluate whether a behavior change intervention, delivered through a shared medical appointment (SMA) model, can improve self-management behaviors and health outcomes among community-based…
- Trial name
- NCT07128745
- Testing
- Shared Medical Appointment + Self-Management Strategy, Usual Care + Self-Management Handbook
- Where
- 2 sites in China
- Volunteers
- 280 people
- Sponsor
- Peking University Third Hospital
Deep Learning, Ultrasound
Construction of a Deep Learning-Based Precise Diagnostic Framework for Bladder Tumors Using Ultrasound: A Multicenter, Ambispective Cohort Study
This study aims to develop an ultrasound image-based deep learning system to enable automatic segmentation, T-staging, and pathological grading prediction of bladder tumors.
- Conditions
- Deep Learning, Ultrasound, Bladder Cancer
- Trial name
- BCA-AI-US (NCT07111364)
- Testing
- observational diagnostic model development
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Peking University First Hospital
Anterior Cruciate Ligament Reconstruction
Comparison of the Efficacy of Telerehabilitation and In-person Rehabilitation Based on Wearable Devices After ACLR Surgery: a Multicenter Randomized Controlled Trial
Purpose: Investigate whether telerehabilitation based on wearable devices is clinically as effective as in-person rehabilitation for ACLR patients. Subjects: 164 patients aged ≥18 years who underwent ACLR.
- Trial name
- NCT06327555
- Testing
- telerehabilitation, in-person rehabilitation
- Where
- China
- Volunteers
- 164 people
- Sponsor
- Peking University Third Hospital
Chronic Myelomonocytic Leukemia (CMML), Immune Reconstitution
The Kinetics Profiling of Immune Reconstitution and Clinical Outcomes
Chronic myelomonocytic leukemia (CMML) is a clonal hematopoietic malignancy with poor prognosis. Allogeneic hematopoietic stem cell transplantation (HSCT) remains the only potentially curative treatment.
- Trial name
- NCT07113730
- Testing
- immune reconstitution
- Volunteers
- 300 people
- Sponsor
- Peking University People's Hospital
HPV Infection, Cervical Disease
Impact of HPV Vaccination on HPV Infection and Cervical Related Disease Burden in Real-World Settings (HPV-RWS)
Take AS04 adjuvanted HPV16/18 vaccine as an example to evaluate the impact of HPV vaccination on HPV infection and related disease burden in the real world based on prospective cohort and Yinzhou Regional Health Information…
- Trial name
- HPV-RWS (NCT05341284)
- Testing
- Questionnaire Survey and Cervical Cancer Screening
- Volunteers
- healthy volunteers welcome
- Sponsor
- Peking University
Non-Small Cell Lung Cancer
A Perioperative Comprehensive Diagnosis and Treatment System for Lung Cancer in the Era of Neoadjuvant Immunotherapy
The goal of this study is to develop and refine an integrated minimally invasive care pathway for resectable lung cancer in the immunotherapy era, establishing a novel precision perioperative immunotherapy paradigm encompassing…
- Trial name
- NCT07119190
- Volunteers
- 350 people
- Sponsor
- Peking University People's Hospital
Coronary Microvascular Disease
A Clinical Study of Fundus OCTA for the Identification of CMD
Coronary microvascular dysfunction (CMD) carries an increased risk of adverse cardiovascular clinical outcomes. The association between fundus microcirculation changes and coronary microcirculation is not well understood.
- Trial name
- NCT05743140
- Testing
- CaIMR
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Peking University First Hospital
Conditions or Focus of Study: B7-H3 Positive Relapsed/Advanced Malignant Solid Tumor
UTAA06 Injection for Treatment of Advanced Malignant Solid Tumors
This is a single-arm, open, early-stage clinical study. The main purpose of this study is to explore the maximum tolerated dose (MTD), the optimal phase II recommended dose, safety, initial anti-tumor activity…
- Trial name
- NCT06372236
- Testing
- UTAA06 injection for treatment of advanced malignant solid tumors
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Peking University
Coronary Microvascular Dysfunction
A Study on the Impact of Bivalirudin Usage During PCI for High-risk Plaques on Post-PCI Coronary Microcirculation.
In this study, investigators enrolled patients with coronary heart disease who were scheduled to undergo percutaneous coronary intervention (PCI) and had high-risk plaques according to computed tomography angiography (CTA).
- Trial name
- PCI (NCT05984537)
- Testing
- Bivalirudin, standard heparin
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Peking University First Hospital
Nephrotic Syndrome, Hypoalbuminemia
Edoxaban Steady-State PK/PD in Adults With Nephrotic Syndrome
A study to evaluate the impact of nephrotic syndrome on the steady state pharmacokinetics and pharmacodynamics of edoxaban compared to health volunteers, and whether edoxaban can provide an equivalent anticoagulant effect to…
- Trial name
- NCT07116239
- Testing
- Edoxaban 60 mg, Enoxaparin 40 mg
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Hyperuricemia
Clinical Effect Observation of Barley Green Intervention in Hyperuricemia Population and Related Mechanism Study of Xanthine Oxidase
This study aims to explore the changes in metabolic-related indicators in patients with hyperuricemia under the intervention of barley green, reveal the clinical effect of barley green in regulating uric acid metabolism, and…
- Trial name
- NCT06876909
- Testing
- barley green
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Peking University People's Hospital
Immune Thrombocytopenia
Teriflunomide Plus High-dose Dexamethasone as First-line Treatment in Newly Diagnosed Primary Immune Thrombocytopenia
A randomized, open-label, multicenter study to compare the efficacy and safety of teriflunomide plus high-dose dexamethasone compared to high-dose dexamethasone monotherapy for the first-line treatment of adults with newly…
- Trial name
- NCT06176235
- Testing
- Teriflunomide, Dexamethasone
- Where
- 10 sites in China
- Sponsor
- Peking University People's Hospital
Stress, Emotional, Stress-related Mental Disorders
School-Based Intervention to Enhance Resilience and Stress Coping in Rural Chinese Adolescents
This study aims to evaluate the effectiveness of school-based psychological interventions in improving stress resilience and coping skills among adolescents in rural China.
- Trial name
- EASY (NCT07115186)
- Testing
- Psychoeducation, guided written therapy, wait-list condition
- Where
- China
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- Peking University
Complication,Postoperative, Stoma
Chinese Ostomy Collaboration Group (COCG) Clinical Study -SITI Classification
Colorectal cancer is an important cancer worldwide, and its incidence is increasing year by year. A large proportion of patients may require diverting stoma or even permanent stoma after surgery.
- Trial name
- COCG-SITI (NCT07111429)
- Testing
- Novel severity grading system of stoma-related complication in cancer patients
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Peking University Cancer Hospital & Institute
End Stage Renal Disease on Dialysis
Efficacy of pHA130 Hemoadsorption for 4 Hours (p4H Study)
This is an open-label, randomized, crossover study to evaluate the efficacy of extending the duration of hemoadsorption (HA) combined with hemodialysis (HD) from 2 hours to 4 hours for clearing protein-bound uremic toxins, such…
- Trial name
- NCT07111260
- Testing
- pHA130 Hemoadsorption + High-Flux Hemodialysis
- Where
- China
- Volunteers
- 34 people
- Sponsor
- Peking University People's Hospital
Renal Artery Stenosis Atherosclerotic, Secondary Hypertension Renal Arterial
A Placebo-controlled Trial of Fractional Flow Reserve-guided Percutaneous Renal Artery Stenting Among Atherosclerosis Renal-vascular Hypertension Patients
Objective: To determine whether percutaneous renal artery stenting guided by fractional flow reserve (FFR), in addition to standard medical therapy, provides superior therapeutic efficacy compared to medical therapy alone in…
- Trial name
- FAIR (NCT07111442)
- Testing
- renal artery fractional flow reserve measurement, dopamine, renal artery stent
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking University First Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.