Clinical trials: sponsored by Peking University
Blood Pressure, Dexmedetomidine
Intraoperative Goal-directed Blood Pressure and Dexmedetomidine on Outcomes
Perioperative organ injuriy remain an important threat to patients undergoing major surgeries. Intraoperative hypotension is associated with an increase in postoperative morbidity and mortality.
- Conditions
- Blood Pressure, Dexmedetomidine, High-risk Patients, Abdominal Surgery
- Trial name
- NCT03933306
- Testing
- Dexmedetomidine, Goal-directed blood pressure management, Routine blood pressure management
- Where
- China
- Volunteers
- 496 people
- Sponsor
- Peking University First Hospital
Immune Thrombocytopenia (ITP), Acute Ischemic Stroke
Longitudinal Cohort Study on Immune Thrombocytopenia Complicated With Acute Ischemic Stroke
Immune thrombocytopenia (ITP) is an acquired bleeding disorder mediated by immune-related platelet destruction and impaired platelet production.
- Trial name
- NCT07070193
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Immune Thrombocytopenia (ITP)
Longitudinal Observational Study on Immune Thrombocytopenia
Immune Thrombocytopenia (ITP) is a bleeding disorder characterized by immune-mediated destruction and/or impaired production of platelets, leading to clinical manifestations such as petechiae, purpura, mucosal bleeding, and in…
- Trial name
- NCT07068425
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Hypertension, Diabetes Mellitus Type 2
County Medical Community-based, Cardiovascular Risk Stratified Integrated Care Model: a Pragmatic Cluster Randomised Control Trial
The goal of this cluster randomized trial is to evaluate the effectiveness of the RISIMA model based on an integrated county healthcare consortium implemented by multi-level family health teams (FHTs)on patients with diabetes…
- Conditions
- Hypertension, Diabetes Mellitus Type 2, Cardiovascular Diseases
- Trial name
- C-RISIMA (NCT06302127)
- Testing
- Team-based care, Risk-stratified care pathway, Strengthened health education
- Where
- 3 sites in China
- Volunteers
- 2,560 people
- Sponsor
- Peking University
Y-balance, Patellofemoral Pain Syndrome
Assessing Lower Extremity Dynamic Stability in Middle-Aged and Elderly Patients With Patellofemoral Pain Using the Y-Balance Test
Background: Patellofemoral pain syndrome (PFPS) is a common functional disorder of knee joint. Its etiology involves biomechanical abnormalities and dynamic stability defects.
- Trial name
- NCT07068984
- Testing
- Differences between lower limb balances were assessed by the Y-Balance test
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Peking University Third Hospital
Immune Thrombocytopenia
The Combination of Upadacitinib and High-dose Dexamethasone as First-line Treatment in Adult Immune Thrombocytopenia
Randomized, open-label, multicenter study to compare the efficacy and safety of Upadacitinib plus high-dose dexamethasone compared to high-dose dexamethasone monotherapy for the first-line treatment of adults with primary immune…
- Trial name
- NCT07064889
- Testing
- Dexamethasone, Upadacitinib
- Where
- China
- Volunteers
- 132 people
- Sponsor
- Peking University People's Hospital
Sarcoma, Biomarkers
The Exploration of OX40 (CD134) Expression Levels in Sarcoma Specimens and Its Clinical Application in Prognosis Determination
This study aims to investigate the expression of OX40 (CD134) in sarcomas and its impact on prognosis, with the goal of identifying novel biomarkers for early resistance detection and optimizing treatment strategies for sarcoma…
- Conditions
- Sarcoma, Biomarkers, Progression
- Trial name
- NCT06751251
- Testing
- IHC: Immunohistochemistry, RNA-seq
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking University People's Hospital
Immune Thrombocytopenia (ITP)
Iguratimod Plus Low-dose Rituximab vs Low-dose Rituximab in Corticosteroid-resistant or Relapsed ITP
Randomized, open-label, multicentre study to assess the efficacy and safety of the combination of low-dose rituximab and Iguratimod in patients with steroid-resistant/relapsed ITP.
- Trial name
- NCT07057778
- Testing
- Iguratimod, low-dose rituximab
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University People's Hospital
Mechanically Ventilated Patients With Shock
The Impact of Different Sedation Regimens on Hemodynamics in Patients Undergoing Mechanical Ventilation With Shock
Mechanical ventilation is a common therapeutic intervention in the intensive care unit (ICU). However, patients undergoing mechanical ventilation often experience agitation, unplanned extubation, patient-ventilator asynchrony…
- Trial name
- NCT07037615
- Volunteers
- 50 people
- Sponsor
- Peking University People's Hospital
Circumcision
Hydrodissection Circumcision Versus Conventional Circumcision
Over a period of more than 3 years (January 2021 to February 2024), 96 males (aged 6-35 years; average 12.3 years) who underwent circumcision were randomly divided into three groups: HC, sCC (tissue sparing), and uCC (tissue…
- Trial name
- Circumcision (NCT07056452)
- Testing
- hydrodissection technique
- Where
- 2 sites in China
- Volunteers
- 96 people
- Sponsor
- Peking University
Minimal Invasive Surfactant Administration in Two Different Non-invasive Ventilation Modes to NRDS Infants
NIV-MISA-NRDS Trial: a Multicenter Study in China
BACKGROUND Non-invasive ventilation (NIV) treatment have been developed to minimize lung damage and to avoid invasive mechanical ventilation (IMV) in preterm infants, especially in those with gestational age less than 30 weeks.
- Trial name
- NCT05137340
- Testing
- Nasal continuous positive airway pressure, Non-invasive positive pressure ventilation
- Where
- China
- Volunteers
- 312 people
- Sponsor
- Peking University Third Hospital
Radiation - Induced Proctitis
A Randomized Controlled Trial of Five - Flavor Sophora Flavescens Enteric - Coated Capsules for Radiation - Induced Proctitis After Pelvic Radiotherapy
The goal of this single - center, prospective, randomized controlled study is to assess the therapeutic effects of five - flavor sophora flavescens enteric - coated capsules on radiation - induced proctitis in patients who have…
- Trial name
- NCT07053761
- Testing
- five - flavor sophora flavescens enteric - coated capsules plus glutamine and warm - water sitz baths, glutamine and warm - water sitz baths
- Volunteers
- 124 people
- Sponsor
- Peking University First Hospital
High - Risk NMIBC
Observational Clinical Study on High - Risk NMIBC Patients Choosing Trimodality Bladder - Sparing Therapy
The goal of this observational study is to assess the safety and efficacy of trimodality bladder - sparing therapy in high - risk NMIBC patients.
- Trial name
- NCT07053748
- Testing
- Trimodality Bladder-preserving Therapy
- Volunteers
- 30 people
- Sponsor
- Peking University First Hospital
Bladder (Urothelial, Transitional Cell) Cancer
Observational Clinical Study of Patients With Muscle - Invasive Bladder Cancer Undergoing Bladder Preservation Therapy After Neoadjuvant Therapy
The goal of this observational study is to evaluate the safety and efficacy of neoadjuvant therapy followed by bladder - preserving TMT in patients with MIBC.
- Trial name
- NCT07053722
- Testing
- NA-TMT
- Volunteers
- 30 people
- Sponsor
- Peking University First Hospital
Endometrial Cancer
Calcium Channel Blocker Amlodipine for Endometrial Cancer Therapy
To explore the treatment efficacy of Progesterone Therapeutic Regimen Plus Amlodipine in patients with early endometrial carcinoma (EEC) for conservative treatment.
- Trial name
- NCT06942377
- Testing
- Amlodipine
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Peking University People's Hospital
Bladder (Urothelial, Transitional Cell) Cancer
An Exploratory Clinical Study of Nimotuzumab in Bladder - Sparing Chemoradiotherapy for Muscle - Invasive Bladder Cancer
The goal of this exploratory study is to evaluate the safety and efficacy of nimotuzumab combined with chemoradiotherapy in bladder - preserving treatment for MIBC patients who are ineligible for or decline radical cystectomy.
- Trial name
- NCT07053735
- Testing
- Nimotuzumab and Radiotherapy
- Volunteers
- 30 people
- Sponsor
- Peking University First Hospital
Depression - Major Depressive Disorder
Individualized Exploration of Aerobic Exercise-assisted Treatment of Depression
The goal of this project is to quantify the relative effectiveness of aerobic exercise monitored by smart wristbands in assisting the treatment of depression and improving cognitive function.
- Trial name
- NCT06594588
- Testing
- Aerobic exercise
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Peking University
Prostate Cancer
Comparison of MRI Artificial Intelligence-guided cTB Versus Routine cTB in Prostate Cancer Diagnosis
The goal of this multicenter clinical trial is to compare the cancer detection rates of MRI artificial intelligence-guided cTB (AI-cTB) and routine cTB, and explore the added value of using AI for the guidance of cTB.
- Trial name
- NCT06392737
- Testing
- MRI-AI guided cognitive prostate targeted biopsy, Routine cognitive prostate targeted biopsy
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Peking University First Hospital
Pediatric, Neurosurgery
Remimazolam and Emergence Delirium in Pediatrics
Emergence delirium is a common complication in pediatrics undergoing neurosurgery. Previous study showed that a single bolus of remimazolam was associated with lower incidence of postoperative agitation.
- Conditions
- Pediatric, Neurosurgery, Sevoflurane Anesthesia, Remimazolam
- Trial name
- NCT07046364
- Testing
- Remimazolam, Normal Saline
- Where
- 2 sites in China
- Volunteers
- 248 people
- Sponsor
- Peking University First Hospital
TNBC - Triple-Negative Breast Cancer
Trop-2 Targeted PET Probes in Advanced TNBC
According to inclusion and exclusion criteria, 20 eligible subjects with triple-negative breast cancer (TNBC) scheduled to receive sacituzumab govitecan were screened.
- Trial name
- NCT07046455
- Testing
- Sacituzumab Govitecan (SG)
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Peking University Cancer Hospital & Institute
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.