Clinical trials: sponsored by Penn State University
Chronic Stress, Anxiety
Preventing Internalizing in Preadolescents Exposed to Chronic Stress
Racial and socioeconomic disparities in physical and mental health problems are large, persistent, and severe; begin during childhood; and stem from in part damage to physiologic stress response systems caused by chronic stress.
- Conditions
- Chronic Stress, Anxiety, Depression
- Trial name
- NCT02764138
- Testing
- Building a Strong Identity and Coping Skills
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Penn State University
Eating Behavior
Child Sweet and Savory Snack Study
The purpose of this study is to determine how consumption of a snack food affects the hedonic ratings of that snack food compared to other foods.
- Trial name
- NCT06137677
- Testing
- Sweet Snack, Savory Snack
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Penn State University
Effect of Drug
Topical Cannabidiol Application and Skin Vascular Reactivity
Cannabidiol, or CBD, is an over-the-counter "nutraceutical" that is more commonly being used by healthy adults for pain management, recovery from strenuous exercise, and general wellness.
- Trial name
- cannabidiol (NCT05456113)
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Penn State University
Stress, Anxiety
Assessing the Impact of VR-Based Observational Mindfulness Meditation on Stress Reduction in Adults
This study investigates the impact of a mindfulness-based intervention using virtual reality (VR) and artificial intelligence (AI) coaching on stress reduction.
- Conditions
- Stress, Anxiety, Depression
- Trial name
- VR-MOM (NCT06704282)
- Testing
- VR Mindfulness Meditation Program
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Penn State University
Sleep
Feasibility of a Bedtime Variability Protocol
The purpose of this study is to find out if parents and children 6-10 years old are willing and able to follow a protocol to be used to study the effects of short and/or variable sleep in children.
- Trial name
- NCT06501690
- Testing
- Late bedtime, Variable bedtime
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Penn State University
Child Obesity, Eating Behavior
Tween Sleep Patterns, Appetite Control, and Environment
The goal of this study is to learn about how children's sleep is related to their eating behaviors the next day, and to learn about factors that relate to eating behaviors and sleep health that are specific to preadolescent…
- Conditions
- Child Obesity, Eating Behavior, Sleep
- Trial name
- TweenSPACE (NCT05853393)
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Penn State University
End-stage Renal Disease
Network Interventions to Reduce Disparities in Living Kidney Donation
For this current phase of the larger project, the investigators will survey transplant candidates as well as the participants family and friends to understand the barriers to volunteering and evaluation.
- Trial name
- NCT05255757
- Testing
- Script Intervention, Search Intervention
- Where
- 2 sites in United States
- Volunteers
- 164 people
- Sponsor
- Penn State University
Eating Behavior
Child Snack Variety Study
The purpose of this study is to determine how consumption of a snack food at a first course affects the hedonic ratings of that snack food compared to other foods, and how it affects intake of a second course.
- Trial name
- NCT06427837
- Testing
- Same 2nd course, Different 2nd course
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Penn State University
Autism Spectrum Disorder, Autism
Using Serious Games to Improve Social Skills in Autism
The investigators will conduct a small-scale randomized control trial comparing the intervention game to an active control game, and will assess outcomes at multiple time points (pre-, post-, 6-month follow-up).
- Trial name
- SAGA (NCT03690661)
- Testing
- Intervention Video Game
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Penn State University
Literacy
Effect of the ALL App on Literacy for Children Who Use AAC
The goal of this clinical trial is to test a phonics-based literacy program for children with limited or no speech who use augmentative and alternative communication. More specifically, this study aims to: 1.
- Trial name
- NCT05602181
- Testing
- ALL Phonics Instruction, ALL Sight Word Instruction
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Penn State University
Parent-Child Relations
Trial of Transition to Parenthood Program for Couples
This is a research study to evaluate the effectiveness of the Family Foundations program and to better understand how families cope with having a new baby.
- Trial name
- FF2 (NCT01907412)
- Testing
- Family Foundations Coparenting Program
- Where
- United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Penn State University
Alzheimer Disease
A Family-centered Intervention for Acutely-ill Persons With Dementia
This study will address the effectiveness of Family-centered Function Focused Care (Fam-FFC). Fam-FFC is a theoretically-based approach to care in which family caregivers partner with nurses to prevent functional decline and…
- Trial name
- NCT03046121
- Testing
- Family-centered Function-focused Care (Fam-FFC)
- Where
- 3 sites in United States
- Volunteers
- 461 people
- Sponsor
- Penn State University
Insomnia, Alzheimers Disease Related Dementias
Enhanced CBTi for Older Adult Sleep and Cognition
This randomized clinical trial on 60+ aged and independent-living healthy individuals with symptoms of insomnia will attempt to improve sleep and health outcomes related to sleep with enhancement of a clinical intervention…
- Trial name
- R44 (NCT05015803)
- Testing
- CBTi with Application, CBTi, Sleep Hygiene Education
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Penn State University
Type2 Diabetes
Almond Butter and Fasting Glucose
A two-period randomized crossover study will be conducted to determine the effect of almond butter as an evening snack on fasting blood glucose in adults with type 2 diabetes, not taking insulin.
- Trial name
- NCT03826472
- Testing
- Almond Butter
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Penn State University
Hypertension,Essential
Peripheral Vascular Effects of Sulfhydryl-containing Antihypertensive Pharmacotherapy on Microvessels in Humans
High blood pressure can cause physical changes to the blood vessels of the body (remodeling). If a person who has high blood pressure also has a lot of blood vessel remodeling with their condition, they are more likely to have…
- Trial name
- H2SPharm (NCT03179163)
- Testing
- Captopril Pill, Enalapril Pill, Hydrochlorothiazide
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Penn State University
Dementia, Staff Attitude
Pilot Testing Decision Making in Aging and Dementia for Autonomy Program in Nursing Homes
The purpose of this study is to adapt, pilot test, and evaluate the feasibility, acceptability, and preliminary effectiveness of DIGNITY (Decision-making In aGing and demeNtIa for auTonomY) for Preference-Based Care in Nursing…
- Conditions
- Dementia, Staff Attitude, Nurse's Role, Nursing Homes
- Trial name
- DIGNITY (NCT05618678)
- Testing
- DIGNITY, Infection Control
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Penn State University
Pediatric Obesity, Inhibition
Brain Mechanisms of Overeating in Children
The proposed research will follow healthy weight children who vary by family risk for obesity to identify the neurobiological and appetitive traits that are implicated in overeating and weight gain during the critical…
- Conditions
- Pediatric Obesity, Inhibition, Decision Making, fMRI
- Trial name
- RO1 (NCT03341247)
- Where
- United States
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Penn State University
Eating Behavior
Combined Effects of Sequential Variety and Portion Size on Meal Intake of Women
The primary purpose of this study is to investigate the combined effects of sequential meal variety and portion size on food intake at a meal.
- Trial name
- NCT05485168
- Testing
- Sequential Variety, Single-Food, Small Portion
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Penn State University
Cardiovascular Risk Factor
The Effect of Spice Consumption on Postprandial Vascular Function
A 3-period randomized cross-over, controlled feeding study will be conducted to determine the effect of chronic spice consumption on postprandial vascular function.
- Trial name
- NCT03063320
- Testing
- Spice blend
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Penn State University
Glasses
Light Sleep: Screen Use and Sleep Health
The Phone Sleep Study is being done to find out whether wearing blue light-blocking glasses in the evening improves subsequent sleep.
- Trial name
- LS (NCT05342662)
- Testing
- Blue light-blocking glasses, Glasses with clear lenses
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Penn State University