Clinical trials: sponsored by Poitiers University Hospital
Respiration Disorder, Respiratory Failure
Impact of the Inspiratory Cortical Control on the Outcome of the Ventilatory Weaning Test in Patients Intubated in Resuscitation
In case of respiratory distress, patients are intubated to be connected to an artificial respirator to ensure gas exchanges. Before any ventilatory weaning, a breathing test in spontaneous ventilation under artificial nose is…
- Conditions
- Respiration Disorder, Respiratory Failure, Weaning Failure, Respiratory Compensation
- Trial name
- NCT03372252
- Testing
- Electroencephalography
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Poitiers University Hospital
Stroke
Evaluation of the PS100B for the Diagnostic of Stroke With Patients Out of Delay for Thrombolysis or Thrombectomy
Numerous patients are addressed to the Emergency Department for unspecific symptoms which can evoke a stroke, such as vertigo, isolated motor deficit, behavior disorder.
- Trial name
- NCT05002400
- Where
- 2 sites in France
- Volunteers
- 179 people
- Sponsor
- Poitiers University Hospital
Tension-Type Headache Episodic
Pilot Study of the Osteo-Fluidic-Sensitive (OFS) in Tension-type Headache.
The hypothesis of the study is the Osteo-fluidic-Senstive is effective for lowering headache pains (Reduction of the number of days of headaches per month) for patients having frequent episodic tension-type headache.
- Trial name
- NCT05229224
- Testing
- Osteo fluidic Sensitive méthod
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Cerebrospinal Fluid, Healthy Subjects or Volunteers
Dynamic Measurement of Cerebrospinal Fluid in Healthy Subjects: Pilot Study
This research will enhance our knowledge and understanding of Cerebrospinal Fluid (CSF) circulation around the Central Nervous System (CNS) (brain and spinal cord).
- Trial name
- DYNA-LCS P (NCT06743347)
- Testing
- MRI Contrast
- Where
- France
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Obesity, Stigma, Weight
Interventions to Remedy the Negative Effects of Obesity Stigma
This project proposes to integrate a psychosocial approach into the therapeutic patient education program (TPE) at "La Vie la Santé", an innovative health promotion platform at Poitiers University Hospital.
- Trial name
- NCT05906238
- Testing
- STEREOBES Workshops, Un Poids en moins
- Where
- France
- Volunteers
- 210 people
- Sponsor
- Poitiers University Hospital
Atopic Dermatitis, Staphylococcus Aureus
Staphylococcal Toxins in Atopic Dermatitis and Eczema Herpeticum
Atopic dermatitis (AD) is the most common chronic inflammatory skin disease. Clinical studies have demonstrated a link between staphylococcal skin colonization and the pathogenesis of AD, but the implication of bacterial…
- Conditions
- Atopic Dermatitis, Staphylococcus Aureus, Bacterial Toxins, Immune Response
- Trial name
- STADEH (NCT04274348)
- Testing
- Skin biopsies and blood samples
- Where
- 2 sites in France
- Volunteers
- 41 people
- Sponsor
- Poitiers University Hospital
Systemic Sclerosis (SSc), Magnetic Resonance Imaging (MRI)
7.0 Tesla Resonance Magnetic Imaging of the Hand in Systemic Sclerosis
Systemic sclerosis (SSc) is a rare systemic autoimmune disease with specific osteoarticular pattern of unknown mechanism. Ischemic phenomenon have been suggested to participate to the osteoarticular involvement in SSc.
- Trial name
- PREM'S (NCT04223817)
- Testing
- 7.0 T RMI
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Poitiers University Hospital
Minor Traumatic Brain Injury, Treatment by Antiplatelet
Interest of S100B Protein for Patient Victim of Minor Traumatic Brain Injury and Treated by Antiplatelet
All the patients admitted in emergency department for minor traumatized cranial, with antiplatelet therapy, can be included, after checked inclusion and non inclusions criterias.
- Trial name
- PETEChIA (NCT03780062)
- Testing
- S100B protein dosing
- Where
- 4 sites in France
- Volunteers
- 720 people
- Sponsor
- Poitiers University Hospital
Huntington Disease
Study to Evaluate Music Therapy on Irritability and Impulsivity in Patients With Huntington's Disease (MUSIC-HD)
The study is an open-label clinical trial evaluating whether music therapy combined with conventional management reduces irritability and impulsivity in 15 patients with early-stage Huntington's disease.
- Trial name
- MUSIC-HD (NCT06414967)
- Testing
- Music Intervention
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Poitiers University Hospital
Smoking Cessation
Study to Evaluate Music Therapy and Nicotine Replacement Therapy on Craving Related to Smoking Cessation in Students
The study is a randomized, controlled trial comparing music therapy associated to NRT versus NRT alone to evaluate the value of music therapy in improving the management of craving among 120 student smokers (18 to 25 years old).
- Trial name
- NCT05589220
- Testing
- Music Intervention, Nicotine replacement
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Poitiers University Hospital
Paroxysmal Atrial Fibrillation
Baroreflex Sensitivity in Patients Undergoing Ablation of Atrial Fibrillation
Atrial fibrillation is the most common arrhythmia. The posterior surface of the left atrium is covered by an extensive network belonging to the autonomic nervous system that can be damaged during the ablation.
- Trial name
- BARO-AF (NCT04503122)
- Testing
- pulmonary vein isolation
- Where
- France
- Volunteers
- 116 people
- Sponsor
- Poitiers University Hospital
Breast Cancer, Digestive Cancer
Interest of Circulating Tumor DNA in Digestive and Gynecologic/Breast Cancer
Circulating tumor DNA (ctDNA) offers the possibility of accessing the tumor genome from circulating blood through a simple blood test.
- Conditions
- Breast Cancer, Digestive Cancer, Gynecologic Cancer, Circulating Tumor DNA
- Trial name
- NCT04530890
- Testing
- Blood samples
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Poitiers University Hospital
Acute Respiratory Distress Syndrome
Avalanche Phenomenon During Airways Opening in Acute Respiratory Distress Syndrome
Acute respiratory distress syndrome accounts for 23% of mechanically ventilated patients and is associated with high mortality rate.
- Trial name
- AVALANCHE (NCT05224323)
- Testing
- Airway pressure, flow, esophageal pressure, ventilation distribution
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Poitiers University Hospital
Complete Vertical Midline Sternotomy / Cardiac Surgery
Prevention of the Risk of Complete Sternotomy Scar Dehiscence in Cardiac Surgery: A Clinical Investigation Comparing Negative Pressure Wound Therapy (NPWT) vs. Standard Dressing
Mediastinitis is the most feared infectious complication after cardiac surgery. Several risk factors are known such as: obesity, diabetes, chronic obstructive pulmonary disease, double breast sampling, immunodeficiency…
- Trial name
- PRISTER (NCT06207630)
- Testing
- Dressing Device
- Where
- 5 sites in France
- Volunteers
- 660 people
- Sponsor
- Poitiers University Hospital
HELICOBACTER PYLORI INFECTIONS
Feasibility Study to Diagnose Helicobacter Pylori in the Paediatric Population Using Non-invasive Fecal Analysis
Helicobacter pylori infection is a widespread bacterial disease affecting nearly half of the world's population. In children, the infection displays distinct features versus adults, with lower prevalence, variable symptoms, and…
- Trial name
- HEPYCA (NCT07083804)
- Testing
- Gastric biopsies, Stool sampling
- Where
- France
- Volunteers
- 188 people
- Sponsor
- Poitiers University Hospital
Advanced Practice Nursing, Emergency Departments
Evaluation of the Impact of Emergency Advanced Practice Nurses One Year After Implementation in the Adult Emergency Department of a French University Hospital
In France and around the world, emergency care facilities are facing increasing demand, with rising waiting times. Differentiating care pathways, notably by opening a fast-track unit, helps to improve patient flow and waiting…
- Conditions
- Advanced Practice Nursing, Emergency Departments, Patient Satisfaction
- Trial name
- IMPACTED (NCT07004270)
- Where
- France
- Volunteers
- 921 people
- Sponsor
- Poitiers University Hospital
COPD, Pulmonary Hypertension
Effectiveness and Tolerance of Respiratory Rehabilitation in Pulmonary Hypertension Associated With Chronic Obstructive Pulmonary Disease
Observational study summary The goal of this observational study is to determine whether an outpatient pulmonary rehabilitation (PR) program-already known to be effective and safe for chronic obstructive pulmonary disease…
- Trial name
- REHABTP (NCT07202793)
- Where
- France
- Volunteers
- 59 people
- Sponsor
- Poitiers University Hospital
Respiratory Failure With Hypoxia, Respiratory Failure, ICU
Weaning From High Flow Nasal Oxygen in Acute Respiratory Failure : a Target Trial Emulation
Acute respiratory failure is a frequent reason for admission to the intensive care unit (ICU). It is associated with high healthcare consumption and mortality.
- Conditions
- Respiratory Failure With Hypoxia, Respiratory Failure, ICU, High-Flow Nasal Oxygen Therapy
- Trial name
- HFNO-Weaning (NCT07030413)
- Where
- 3 sites in France
- Volunteers
- 2,000 people
- Sponsor
- Poitiers University Hospital
Metastatic Colon Cancer
Detection of Brain Metastasis by MRI in Metastatic Colorectal Cancer Patients
The aim of this study is to prospectively determine the incidence of brain metastases in metastatic colorectal cancer patients using systematic annual screening by MRI.
- Trial name
- NCT03694938
- Testing
- Magnetic resonance imaging
- Where
- 4 sites in France
- Volunteers
- 143 people
- Sponsor
- Poitiers University Hospital
Laparoscopic Surgery, Neuromuscular Blocking Agents
Study of the Relationship Between Curarization and Pneumoperitoneum in Laparoscopic Surgery
The number of surgical procedures is increasing worldwide (1). Laparoscopic surgery is one of the surgical techniques that has become indispensable. Laparoscopic surgery is less invasive than laparotomy.
- Conditions
- Laparoscopic Surgery, Neuromuscular Blocking Agents, Pneumoperitoneum
- Trial name
- PneumandTOF (NCT07005518)
- Testing
- No Intervention: Observational Cohort
- Volunteers
- 200 people
- Sponsor
- Poitiers University Hospital