Clinical trials: sponsored by Region Skane
Surgery--Complications
Does Prehabilitation Improve Outcome in Coloncancer Surgery?
The study aims to find out if complications after surgery for large bowel (colon) cancer can be reduced or avoided in the most frail and elderly by letting them go through an exercise- and diet regime prior to the surgical…
- Trial name
- PRIO (NCT04199208)
- Testing
- Prehabilitation and Immunonutrition, Standard Care Arm
- Volunteers
- 160 people
- Sponsor
- Region Skane
Diabetes Mellitus, Microvascular Coronary Artery Disease
Study in Diabetes Mellitus Patients Without Prior Myocardial Infarction or Stroke Undergoing Elective Percutaneous Coronary Intervention.
This study is designed to test the hypothesis that ticagrelor is superior to clopidogrel, in improving coronary microvascular function, as measured by coronary flow reserve (CFR) in patients with T2DM at high risk of…
- Trial name
- AUGEAS (NCT04069234)
- Testing
- Ticagrelor, Clopidogrel
- Sponsor
- Region Skane
Whiplash Injuries
Is Chronic Whiplash-associated Pain of Neurogenic Origin?
The purpose of this study is to compare the effects of neurolysis with the effects of a exercise program on pain and other symptoms in individuals with chronic whiplash (WAD II-III).
- Trial name
- NCT02692937
- Testing
- Neurolysis, Traditional neck-specific exercise program
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Region Skane
Aortic Valve Disease, Stroke
Swedish Study on STroke After TAVR
This study aims at studying the frequency of late stroke after transcatheter aortic valve replacement/implantation
- Trial name
- SWESTAT (NCT04086836)
- Testing
- TAVR
- Where
- Sweden
- Volunteers
- 4,600 people
- Sponsor
- Region Skane
Infective Endocarditis of Aortic Valve
Infective Endocarditis After TAVR
This study aims at studying the frequency of infective endocarditis after transcatheter aortic valve replacement/implantation
- Trial name
- INTENSE (NCT03768180)
- Where
- Sweden
- Volunteers
- 4,600 people
- Sponsor
- Region Skane
Pneumonia
Etiology and Incidence Assessment of Radiographically-confirmed Community Acquired Pneumonia (CAP)
This is an epidemiological study to investigate the etiology of radiographically-confirmed community-acquired pneumonia (CAP) in adults aged ≥18 years.
- Trial name
- OSPIS (NCT03606135)
- Testing
- The Pneumonia Group, The Control Group
- Where
- Sweden
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Region Skane
Esophageal Neoplasm
Endodrill vs. Conventional Biopsy. Diagnostics and Genetic Analysis
Endodrill is a new instrument for biopsy sampling in the GI-channel. The purposes of this study are as follows: Compare the Endodrill instrument with conventional biopsy forceps in terms of ability to establish the correct…
- Trial name
- NCT02601079
- Testing
- Endodrill Biopsy, Conventional Biopsy forceps
- Where
- Sweden
- Volunteers
- 7 people
- Sponsor
- Region Skane
Systemic Sclerosis, Gastrointestinal Complication
Mycophenolate Mofetil Pharmacokinetics in Systemic Sclerosis
Drug of investigation: Mycophenolate mofetil (MMF), given orally as a tablet twice daily. Dosage of drug: This study recruits patients who have been prescribed a steady dose of MMF in the range between 1000 and 3000 mg daily by…
- Trial name
- MMFSSC (NCT03678987)
- Testing
- P-MPA concentration, mycophenolic acid
- Where
- Sweden
- Volunteers
- 35 people
- Sponsor
- Region Skane
Stroke
Structured Post-stroke Follow-up in Malmö, Sweden (SUESIM)
Background Stroke-related medical complications and health problems are common among stroke survivors. Post-stroke Checklist (PSC), developed by an international expert group, and can be used as a clinical tool to identify common…
- Trial name
- SUESIM (NCT04295226)
- Testing
- Structured follow-up after stroke.
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Region Skane
Stroke
A Trial of Nature-based Post-stroke Fatigue Rehabilitation (NASTRU)
The aim of NASTRU was to examine whether ten weeks of nature-based rehabilitation, as add-on to standard management, could influence post-stroke fatigue (primary outcome), depression, work ability or functional outcome (secondary…
- Trial name
- NASTRU (NCT02435043)
- Testing
- Nature based rehabilitation, standard management after stroke
- Where
- Sweden
- Volunteers
- 101 people
- Sponsor
- Region Skane
Neurodevelopmental Disorders, Attention Deficit Hyperactivity Disorder
Validity of Neurocognitive Assessment Methods in Childhood ADHD
The aim of the study is to examine the prospective validity of neurocognitive functions and emotional factors in schoolchildren with ADHD and a control group of typically developing schoolchildren at baseline and after three…
- Trial name
- NCT04201509
- Where
- Sweden
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Region Skane
IBS - Irritable Bowel Syndrome
The Effect of Dietary Intervention on Symptoms, Epigenetics, and Gut Microbiota in IBS
The aim of the present study is to research whether subjects with irritable bowel syndrome (IBS) display epigenetic/genetic changes or altered microbiota compared to a non-IBS control group.
- Trial name
- NCT03306381
- Testing
- Dietary intervention
- Where
- Sweden
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Region Skane
Chronic Kidney Failure, Uremia
Reduction Ratio and Clearance During Hemodialysis With MCO-filter Compared to HDF With Standard High-flux Filter
The Medium Cut-Off dialysis (MCO) membrane has been developed to improve middle molecule removal compared to standard high-flux dialysis filters.
- Conditions
- Chronic Kidney Failure, Uremia, Dialysis
- Trial name
- NCT03437538
- Testing
- MCO-HD, High-flux HDF
- Where
- Sweden
- Volunteers
- 18 people
- Sponsor
- Region Skane
Parents
New Programme for Antenatal Preparation for Early Parenthood
Becoming a parent is a challenging stage in life, which provokes feelings of both excitement and insecurity; parents strive to develop confidence in their parenting role.
- Trial name
- NCT03679520
- Testing
- New programme, Regular programme
- Where
- 7 sites in Sweden
- Volunteers
- 71 people
- Sponsor
- Region Skane
Breast Cancer
Malmö Breast Tomosynthesis Screening Trial
To compare digital breast tomosynthesis (DBT) with full field digital mammography (FFDM) regarding effectiveness as screening modalities.
- Trial name
- MBTST (NCT01091545)
- Testing
- DBT and FFDM
- Where
- Sweden
- Volunteers
- 15,000 people
- Sponsor
- Region Skane
Effects of; Anesthesia, Spinal and Epidural, in Pregnancy
Influence of Maternal Postioning on Spread of Local Anesthetic After Epidural Analgesia
The purpose of this study is to determine if a lateral positioning of the pregnant woman after epidural analgesia increases the incidence of unilateral functioning epidurals.
- Trial name
- NCT02617823
- Testing
- lateral position
- Where
- 2 sites in Sweden
- Volunteers
- 950 people, healthy volunteers welcome
- Sponsor
- Region Skane
Rheumatoid Arthritis
Faecal Analyses in Rheumatoid Arthritis Therapy
This study evaluates the intestinal microbiome and disease activity in patients with rheumatoid arthritis receiving immunosuppressive therapy.
- Trial name
- FART (NCT03775824)
- Testing
- MTX start, TNF start
- Volunteers
- 50 people
- Sponsor
- Region Skane
Drug Utilization Review
Medication Reviews in Elderly in Primary Care
The study is a follow-up of a randomized controlled study performed in 2011-2012 with medication reviews in elderly patients in Sweden. Additional data about mortality and hospital admissions have been collected.
- Trial name
- NCT04040855
- Testing
- Medication review
- Volunteers
- 369 people
- Sponsor
- Region Skane
Clear Cell Renal Cell Carcinoma
Diagnostic Imaging for Clear Cell Renal Cell Carcinoma
The main objective is to study whether imaging detection of the biomarker DAT can be used to detect kidney tumors identified by computer tomography (CT), which are pathologically assesses as being of the clear cell subtype.
- Trial name
- RCCSCAN (NCT03185182)
- Testing
- Ioflupane I123
- Where
- Sweden
- Volunteers
- 5 people
- Sponsor
- Region Skane
Osteoarthritis
General or Regional Anesthesia for Hip Surgery
The purpose of this study is to determine whether general anaesthesia or regional anaesthesia is best for patients undergoing Total Hip Arthroplasty.
- Trial name
- NCT01733472
- Testing
- GA-arm, remifentanil, RA-arm
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Region Skane