Clinical trials: sponsored by Region Skane
Cleft Palate, Cleft Lip
Articulation and Phonology in Children With Unilateral Cleft Lip and Palate
The purpose of the study is to assess if there are any differences in the articulatory and phonological competence in pre-school children with unilateral cleft lip and palate (UCLP) who are treated with different surgical methods…
- Trial name
- APCLP (NCT00829101)
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Region Skane
Esophageal and/or Cardia Cancer, Esophagectomy
Paracetamol Absorption Technique as a Method for Measuring Gastric Tube Outlet
Retention of the gastric tube after esophagectomy is a clinically important problem, and there is a need of a simple method to evaluate emptying rate from the gastric tube after esophagectomy.
- Conditions
- Esophageal and/or Cardia Cancer, Esophagectomy, Gastric Pull-up Reconstruction
- Trial name
- NCT02158286
- Testing
- Measuring emptying rate from the gastric tube
- Where
- Sweden
- Volunteers
- 13 people
- Sponsor
- Region Skane
Gastroesophageal Reflux
Laparoscopic Nissen Versus Anterior Partial Fundoplication
The most widely used operative technique for gastroesophageal reflux is total fundoplication where the gastric fundus is sutured around the distal esophagus like a wrap.
- Trial name
- NCT01669330
- Testing
- Nissen fundoplication, Laparoscopic antireflux surgery ad modum Watson
- Where
- 4 sites in Sweden
- Volunteers
- 72 people
- Sponsor
- Region Skane
Distal Radius Fractures
Volar Locking Plate vs Fragment Specific Fixation in Wrist Fractures
The treatment of unstable, non-reducible distal radial fractures is still controversial. The aim of the present study is to compare the subjective, clinical and radiographic outcome of the TriMed fragment-specific system with a…
- Trial name
- NCT01311531
- Testing
- Open reduction and fixation with TriMed fragment-specific system, Open reduction and fixation with TriMed volar locking plate
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Region Skane
Heart Arrest, Out-of-hospital Cardiac Arrest
Cognitive Impairment Following Cardiac Arrest and Target Temperature Management
This is a steering group approved substudy to the Target Temperature Management trial (TTM, ClinicalTrials.gov Identifier: NCT01020916).
- Conditions
- Heart Arrest, Out-of-hospital Cardiac Arrest, Cognition Disorders, Brain Injury
- Trial name
- NCT01946932
- Testing
- Temperature treatment
- Where
- 20 sites in Denmark, Italy and 3 more
- Volunteers
- 287 people
- Sponsor
- Region Skane
Kidney Failure, Renal Failure
Erythropoietin (EPO) to Protect Renal Function After Cardiac Surgery
The purpose of this study is to evaluate the potential of erythropoietin in reducing risk and degree of acute kidney injury after cardiac surgery.
- Trial name
- EPRICS (NCT01423955)
- Testing
- Erythropoietin zeta
- Where
- Sweden
- Volunteers
- 75 people
- Sponsor
- Region Skane
Hepatitis C
Hepatitis C in a Cohort of Patients With Maintenance Therapy for Opiate Dependence - Prevalence, Severity and Outcome of Antiviral Therapy
Hepatitis C is the leading cause of chronic liver disease in industrialized countries, and is the most common indication for liver transplantation.
- Trial name
- NCT01045278
- Testing
- Pegylated interferon-alfa-2b and ribavirin
- Where
- Sweden
- Volunteers
- 277 people
- Sponsor
- Region Skane
Alcohol Consumption
Development of IVR and WEB Alcohol Interventions
The primary aim of the present study is to study the effect of a brief automated alcohol intervention in University students, and if there is a difference in effect between automated brief interventions delivered by internet…
- Trial name
- NCT01923246
- Testing
- Single WEB intervention, Repeated WEB intervention, Single IVR intervention
- Where
- Sweden
- Volunteers
- 1,672 people, healthy volunteers welcome
- Sponsor
- Region Skane
Cancer, Polyp
Compression Anastomosis Using the Compression Anastomotic Ring-locking Procedure (CARP)
The intestinal ends must be rejoined after colonic resection. Conventional methods include sutured and stapled anastomoses, which is associated with 3-6% leakage after colonic surgery.
- Trial name
- NCT01451008
- Testing
- Compression anastomotic ring-locking procedure (CARP)
- Where
- Sweden
- Volunteers
- 25 people
- Sponsor
- Region Skane
Arthritis
General vs. Intrathecal Anesthesia for Total Knee Arthroplasty
Hypothesis: General anesthesia as compared to intrathecal (i.e. spinal anesthesia) anesthesia will result in shorter length of hospital stay for patients undergoing total knee arthroplasty.
- Trial name
- NCT01312298
- Testing
- General anesthesia, Regional anesthesia
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Region Skane
Type 2 Diabetes, Hypertension
10 Prescriptions an Hour. Group Treatment and Physical Activity Referral in a Primary Health Care Setting
The purpose of this study is to determine the effects of group treatment including physical activity referral (PAR) on level of physical activity and quality of life in patients diagnosed with type 2 diabetes and/or hypertension…
- Trial name
- 10PAR (NCT01357304)
- Testing
- Group treatment and PAR
- Where
- Sweden
- Volunteers
- 105 people
- Sponsor
- Region Skane
Affect, Alcohol Consumption
Automated Telephone Follow-up in the Swedish Prison and Probation Services
The purpose of this study is to investigate whether automated telephony may be used for daily assessments of paroled offenders, and whether a brief intervention based on these daily assessments may result in a more positive…
- Conditions
- Affect, Alcohol Consumption, Substance Abuse
- Trial name
- NCT01727882
- Testing
- Brief feedback, Daily assessments
- Where
- Sweden
- Volunteers
- 108 people
- Sponsor
- Region Skane
Angina
Effect of Oxygen During Percutaneous Coronary Intervention for Pain Relief
Nasal oxygen is widely used as pain relief against ischemic pain during Percutaneous Coronary Intervention (PCI). However, to our knowledge no randomised clinical trials have tested this.
- Trial name
- OXYPAIN (NCT01413841)
- Testing
- Nasal oxygen, Regular nasal air
- Where
- Sweden
- Volunteers
- 300 people
- Sponsor
- Region Skane
Osteoarthritis
Early Mobilization After Total Knee Arthroplasty
Patients undergoing elective total knee arthroplasty are randomized to either intrathecal anesthesia, wound infiltration with local anesthetics and standardized postoperative care (NA = neuraxial anesthesia) or general…
- Trial name
- NCT01604382
- Testing
- General Anesthesia, Neuraxial anesthesia
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Region Skane
Carpal Tunnel Syndrome
Steroid Injection Treatment of Carpal Tunnel Syndrome
The aim of this study is to assess the efficacy of injecting steroid into the carpal tunnel in relieving symptoms of carpal tunnel syndrome for at least 1 year with outcomes measured with patient evaluated symptoms score.Out of…
- Trial name
- NCT00806871
- Testing
- Methylprednisolone 40 mg, Methylprednisolone 80 mg, Sodium chloride
- Where
- Sweden
- Volunteers
- 112 people
- Sponsor
- Region Skane
Hypertension
The Impact of Yoga on Blood Pressure and Quality of Life in Patients With Hypertension
The purpose of this study is to determine the effects of yoga on blood pressure and quality of life in patients in primary health care diagnosed with hypertension within the last year.
- Trial name
- YHIP (NCT01302535)
- Testing
- Yoga group with supervision (trainer), Yoga at home
- Where
- Sweden
- Volunteers
- 83 people
- Sponsor
- Region Skane
Inflammation
Significance of Synbiotics on Inflammation and Proliferation of Colonic Mucosa
There is a constant exchange between the gut epithelium and lumen, including microbial interplay. The aim of this study was to investigate dietary test products on inflammatory proliferation markers in the gut, and thereby if the…
- Trial name
- NCT01534572
- Testing
- Lactobacillus, Bifidobacterium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Region Skane
Stress, Complete Psychological Check Up
Cognition and Health in Adolescents, Mindfulness as Prevention of Stress.
The purpose of this study is to determine whether mindfulness is useful as primary prevention for psychological health in highschool students, primarily related to stress, and whether mindfulness can improve cognitive function.
- Conditions
- Stress, Complete Psychological Check Up, Sleep, Cognition - Other
- Trial name
- CHAMPS (NCT01457222)
- Testing
- Mindfulness intervention, Music relaxation
- Where
- Sweden
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Region Skane
Obesity
Impact of Increased Tidal Volumes on Oxygenation and Cardiac Output
General anaesthesia impairs respiratory function in overweight patients. The investigators wanted to compare arterial concentration of sevoflurane and oxygen in overweight patients ventilated with increased tidal volume, or…
- Trial name
- NCT01343017
- Testing
- Ventilatory pattern
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Region Skane
Colorectal Cancer
Information Needs After Surgery for Colorectal Cancer
Aim The overall aim was to investigate information needs after surgery for colorectal cancer and factors explaining information needs, both from the patients' perspective and the next of kin's.
- Trial name
- NCT01303393
- Where
- 3 sites in Sweden
- Volunteers
- 100 people
- Sponsor
- Region Skane