Clinical trials: sponsored by Region Skane
Breast Cancer
ExBRAC- Expressive Writing in Breast Cancer
The study is a randomized trial designed to examine whether an "expressive writing" intervention can affect the quality of life in patients recently diagnosed with breast cancer.
- Trial name
- ExBRAC (NCT07298980)
- Testing
- Expressive Writing
- Where
- Sweden
- Volunteers
- 272 people
- Sponsor
- Region Skane
Cancer
Sense of Security With Access to Palliative Outpatient Clinic
The aim of the study is to evaluate experience of security, accessibility, and avoidable utilization of health care services in patients who have had access to specialized palliative care clinic (SPCC) compared to those who have…
- Trial name
- NCT06393569
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Region Skane
Osteoarthritis
All-poly Versus Metal-backed
The primary objective is the assessment of prosthetic migration results after two years of the Triathlon PS Knee System with all-polyethylene tibial components compared to the Triathlon PS Knee System with metal-backed modular…
- Trial name
- NCT04358601
- Testing
- Triathlon PS Knee System with all-polyethylene tibial components, Triathlon PS Knee System with metal-backed modular components
- Volunteers
- 60 people
- Sponsor
- Region Skane
Breast Cancer
The T-REX Trial: Tailored Regional External Beam Radiotherapy in Clinically Node-negative Breast Cancer Patients With 1-2 Sentinel Node Macrometastases.
T-REX is a randomized multicenter, non-inferiority trial. Aim: To evaluate whether regional radiotherapy may safely be omitted in clinically node negative breast cancer patients with one or two sentinel node macrometastases and…
- Trial name
- T-REX (NCT05634889)
- Testing
- De-escalation
- Where
- 30 sites in Finland, Norway and 1 more
- Volunteers
- 1,350 people
- Sponsor
- Region Skane
Osteo Arthritis of the Knee
Combination of Nerve Blocks and Local Infiltration Analgesia in Knee Arthroplasty
The aim of this clinical randomized trial is to compare local infiltration analgesia (LIA) alone versus the combination of LIA with saphenous nerve (SN) block, block of the nerve to vastus medialis (NVM), and anterior femoral…
- Trial name
- BALIA (NCT07350252)
- Testing
- Ropivacain 5 mg/ml + Clonidine
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Region Skane
Arthroplasty, Replacement, Knee
Evaluation of Triathlon - A New Total Knee Prosthesis System - RSA Triathlon Cruciate Retaining - Cemented vs. Uncemented
The objective is to investigate the Clinical, Radiographic, Roentgen Stereophotogrammetric behaviour and patient outcome when using the Triathlon total knee prosthesis in a prospective randomized clinical trial.
- Trial name
- TriathlonRSA (NCT02525601)
- Testing
- Triathlon CR cemented, Triathlon CR uncemented
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Region Skane
Breath-holding Spell
Breath-holding Spells and Its Management Study
The goal of this prospective population-based study is to evaluate the new disease description and management guidelines for breath-holding spells in children (Hellström Schmidt et al, Acta Paediatrica 2024) below the age of 5…
- Trial name
- BAM (NCT06628271)
- Testing
- Guidelines
- Where
- 12 sites in Sweden
- Volunteers
- 120 people
- Sponsor
- Region Skane
Skin Disease, Eczema
The Skin Microbiota in Skin Disease and Eczema
Background: The skin microbiota influence skin health in several skin diseases and atopic dermatitis (AD). Presence of Staphylococcus have been associated to a sever course of the disease.
- Conditions
- Skin Disease, Eczema, Eczema Atopic Dermatitis
- Trial name
- NCT06924333
- Where
- Sweden
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Region Skane
Infections, Injuries
Digital Versus Telephone Symptom Assessment and Triage in Primary Care
A 'digital-first' approach is currently under implementation in several Swedish regions. The principles behind implementing an online service as an access way to primary care are based on an expectation that it can make access…
- Conditions
- Infections, Injuries, Psychiatric Disorder, Gastro-Intestinal Disorder
- Trial name
- NCT06092866
- Testing
- Digital triage
- Where
- Sweden
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Region Skane
Skin Cancer
Skin Cancer Diagnostics Using Photoacoustic Imaging
In this clinical study, photoacoustic imaging will be used on patients with suspected skin cancer (primarily melanoma, basal cell carcinoma, and squamous cell carcinoma) to determine the tumor borders both superficially and at a…
- Trial name
- NCT06379581
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Region Skane
Mental Illness, Stress
HEAlth Dialogues for Patients With Mental Illness in Primary Care
In the current project, primary health care patients with mental illness such as anxiety, depression, fatigue or sleep disorders will be followed.
- Conditions
- Mental Illness, Stress, Fatigue, Sleep Disorder
- Trial name
- HEAD-MIP (NCT05181254)
- Testing
- health dialogue
- Where
- Sweden
- Volunteers
- 167 people
- Sponsor
- Region Skane
Acute Pancreatitis
Acute Pancreatitis and Coagulation Study
The study aims to investigate pathophysiological changes in coagulation in relation to inflammation in patients with acute pancreatitis. Serum and plasma is sampled repeated days from admission.
- Trial name
- APK (NCT05201053)
- Testing
- Exploratory for different markers
- Where
- Sweden
- Volunteers
- 141 people
- Sponsor
- Region Skane
Lynch Syndrome
Evaluation of Capsule Colonoscopy in Patients With Lynch Syndrome
Lynch syndrome is the most common hereditary cancer syndrome and is caused by pathogenic variants in DNA mismatch repair genes, resulting in a markedly increased lifetime risk of colorectal cancer.
- Trial name
- Lynch syndrome (NCT07445828)
- Testing
- colon capsule endoscopy
- Where
- Sweden
- Volunteers
- 78 people
- Sponsor
- Region Skane
Staphylococcus Aureus Bacteraemia, Staphylococcal Bacteraemia
Comparison of Cloxacillin and Benzylpenicillin in Penicillin Susceptible S. Aureus Bacteraemia
The goal of this study is to investigate if benzylpenicillin is a better treatment option than cloxacillin in patients with penicillin-susceptible Staphylococcus aureus bacteraemia.
- Conditions
- Staphylococcus Aureus Bacteraemia, Staphylococcal Bacteraemia, Staphylococcus Aureus Bloodstream Infections (BSI; Bacteremia), Staphylococcus (S.) Aureus Infection
- Trial name
- COMeBAC (NCT06726395)
- Testing
- Penicillin G_1200mg, cloxacillin
- Where
- Sweden
- Volunteers
- 420 people
- Sponsor
- Region Skane
Adolescent Behavior, Social Media Addiction
Evaluation of a Family-centered Program for Problematic Gaming/Excessive Screen Use
The Family-Centered Program for Problematic Gaming and Excessive Screen Use (FAME) is a pioneering initiative designed to address the growing challenges of excessive screen use and gaming among children and adolescents…
- Conditions
- Adolescent Behavior, Social Media Addiction, Gaming Disorder, Family Relations
- Trial name
- S-FAME (NCT07245862)
- Testing
- Family-centered Program for Problematic Gaming/Excessive Screen Use in a child and adolescent population within Social Services, Control
- Where
- Sweden
- Volunteers
- 170 people
- Sponsor
- Region Skane
Depression, Psychiatric Diagnosis
Long-term Follow-up of Depressive Disorders in Psychiatric Care
The project investigates long-term prognosis and predictors of treatment outcomes for difficult-to-treat depression in patients in secondary psychiatric care.
- Conditions
- Depression, Psychiatric Diagnosis, Personality Disorders, Suicide, Attempted
- Trial name
- NCT07078227
- Testing
- No intervention is used.
- Where
- 2 sites in Sweden
- Volunteers
- 415 people
- Sponsor
- Region Skane
Overweight (BMI > 25)
SSRD and Overweight
The investigators have previously found that a starch- and sucrosereduced diet (SSRD) has led decreased gastrointestinal symptoms in patients with irritabel bowel syndrome (IBS).
- Trial name
- SSRD (NCT07372235)
- Testing
- Dietary intervention with SSRD in combination with feedback information about the metabolic profile, Dietary intervention with SSRD without any feedback on metabolic profile
- Volunteers
- 300 people
- Sponsor
- Region Skane
IBS - Irritable Bowel Syndrome, Sucrase-Isomaltase Deficiency
Sucrase-Isomaltase (SI) Genes and Meal Load
The goal of this interventional study is to examine whether those patients with irritable bowel syndrome (IBS) and a reduced abitility do degrade starch and sugar (lowe levels of enzymes) have lower raise in blood glucose after a…
- Trial name
- SI IBS (NCT07309601)
- Testing
- Meal load
- Where
- Sweden
- Volunteers
- 70 people
- Sponsor
- Region Skane
Benign Breast Tumors, Malignant Breast Tumours
Clinical Explorative Optical Breast Investigations
This study evaluates diffuse reflectance spectroscopy and photoacoustic imaging for differentiating healthy, benign, and malignant breast tissue by identifying their optical profiles.
- Conditions
- Benign Breast Tumors, Malignant Breast Tumours, Healthy
- Trial name
- CLEO-B (NCT06857669)
- Testing
- Diffuse reflectance spectroscopy and Photoacoustic imaging,
- Where
- Sweden
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Region Skane
Mb Crohn, Ulcerative Colitis (UC)
Uneven Nutrition and Life Style as IBD Triggers in Adolescents and Adults
The aims of the study are 1. to determine the effect on dysbiosis, permeability and inflammatory activity after administration of a Mediterranean like diet (a Nordic equivalent, "Nordiet"), 2.
- Trial name
- UNITA (NCT07389161)
- Testing
- Nordiet
- Where
- Sweden
- Volunteers
- 160 people
- Sponsor
- Region Skane