Clinical trials: sponsored by RenJi Hospital
Lung-protective Ventilation
Lung-protective Ventilation During Robot-assisted Laparoscopic Radical Cystectomy
Robot-assisted laparoscopic radical cystectomy (RARC) increases the incidence of postoperative complications. We conducted a study to determine the effect of lung-protective ventilation strategy.
- Trial name
- LPV-RARC (NCT03868319)
- Testing
- lung protective ventilation strategy, nonprotective ventilation
- Where
- China
- Volunteers
- 258 people
- Sponsor
- RenJi Hospital
Respiratory Depression
TAES Improve the Function of Respiration and Circulation on Elderly Patients Undergoing Colonoscopy Procedure
To explore the effectiveness of transcutaneous acupuncture electrical stimulation (TAES), a non-invasive modality in improvement of the function of respiration and circulation on elder patient during colonoscopy.
- Trial name
- NCT03775122
- Testing
- TAES
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
ST Segment Elevation Myocardial Infarction, Left Ventricular Thrombus
Prevention of Post-STEMI Left Ventricular Thrombus With Optimized Anticoagulant (EARLYmyo-LVT Ⅱ)
Left ventricular thrombus is a common complication subsequent to ST-segment elevation myocardial infarction (STEMI) that related to increased embolic events.
- Trial name
- NCT03786757
- Testing
- Rivaroxaban
- Where
- China
- Volunteers
- 200 people
- Sponsor
- RenJi Hospital
Lupus Nephritis
The Iguratimod Effect on Lupus Nephritis (IGeLU)
This study is a 52-week, randomized, open, active-controlled trial of patients with active diffused lupus nephritis, to assess the efficacy and safety of a novel chemical synthetic agent iguratimod.
- Trial name
- IGeLU (NCT02936375)
- Testing
- Iguratimod, Cyclophosphamide, Azathioprine
- Where
- 2 sites in China
- Volunteers
- 120 people
- Sponsor
- RenJi Hospital
Necrosis of Femoral Head, Knee Osteoarthritis
MRI Maker of Perioperative Neurocognitive Disorder
Periperative neurocognitive disorder(PND) is consistently associated with increased morbidity and mortality, but its mechanisms remain unclear.
- Conditions
- Necrosis of Femoral Head, Knee Osteoarthritis, Fracture of Lower Limb
- Trial name
- MRIPND (NCT03773627)
- Where
- China
- Volunteers
- 100 people
- Sponsor
- RenJi Hospital
Kidney Transplant Failure and Rejection
Study in Detection cfDNA for the Early-stage Diagnosis of Acute Rejection Post-renal Transplantation
Acute rejection (AR) is still one of the major complications after kidney transplantation. The current diagnosis measure for AR is primarily pathological puncture test and hematuria biomarker detection, yet due to their inferior…
- Trial name
- NCT03759535
- Testing
- Acute rejection
- Volunteers
- 60 people
- Sponsor
- RenJi Hospital
ST Segment Elevation Myocardial Infarction
Early Intracoronary Administration of Fasudil in the Primary PCI of ST-segment-Elevation Myocardial Infarction
The study aims to evaluate whether an early intracoronary administration of Fasudil Hydrochloride during primary PCI of STEMI can improve epicardial and myocardial perfusion as well as clinical outcomes.
- Trial name
- NCT03753269
- Testing
- Fasudil Hydrochloride
- Volunteers
- 600 people
- Sponsor
- RenJi Hospital
Aspirin as Adjuvant Therapy in Patients With Surgically Treated High Risk Renal Cell Carcinoma
Preventive Effects of Aspirin as Adjuvant Therapy in Patients With Locally Advanced Renal Cell Carcinoma
The study evaluates the protective effect of low-dose aspirin use as adjuvant therapy on locally advanced renal cell carcinoma in users and non-users of aspirin in Renji Hospital, Shanghai, China.
- Trial name
- NCT03734614
- Testing
- Low dose of aspirin
- Where
- China
- Volunteers
- 260 people
- Sponsor
- RenJi Hospital
Upper Tract Urothelial Carcinoma
Feasibility and Safety of Extraperitoneal Laparoscopic Extended Retroperitoneal Lymph Node Dissection at Time of Nephroureterectomy for Upper Tract Urothelial Carcinoma
Extended pelvic lymph node dissection in bladder carcinoma provides staging and, in selected patients, a survival benefit. Recent studies showed the therapeutic benefit of retroperitoneal lymph node dissection (RPLND) in advanced…
- Trial name
- NCT03544437
- Testing
- extraperitoneal laparoscopic extended retroperitoneal lymph node dissection
- Where
- China
- Volunteers
- 40 people
- Sponsor
- RenJi Hospital
Hypoxia, Gastric Cancer
High-flow Nasal Cannula Oxygenation Decrease Hypoxia in Gastroscopy Sedated by Propofol
Hypoxia is the most common adverse events during sedated gastroscopy. In present study, high-flow nasal cannula oxygenation will be utilized in order to reduce the hypoxia.
- Conditions
- Hypoxia, Gastric Cancer, Esophagus Cancer, Adverse Event
- Trial name
- HONCHO (NCT03332433)
- Testing
- High-flow nasal cannula oxygenation
- Where
- 3 sites in China
- Volunteers
- 2,034 people
- Sponsor
- RenJi Hospital
Biliary Atresia Intrahepatic Syndromic Form
Effects of Intraoperative Normal Saline vs Lactated Ringer on Outcomes in Pediatric Liver Transplantation
Lactated Ringer(LR) has been extensively used to maintain and replace intravascular volume in a variety of anesthetic procedures.
- Trial name
- NCT03563378
- Testing
- Lactated Ringer, Normal saline
- Where
- China
- Volunteers
- 200 people
- Sponsor
- RenJi Hospital
Cerebrovascular Disorders, Cognition Disorders
Renji Cerebral Small Vessel Disease Corhort Study
We aim to make clear the impact with the mechanisms of variant pathological injuries on the outcomes of CSVD, to find independent imaging markers and establish prediction model of it.
- Trial name
- RCCS (NCT03544801)
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Lymph Node Dissection
Prognostic Value of Lymph Node Dissection in Patients With Transitional Cell Carcinoma of the Upper Urinary Tract
Recent studies showed the therapeutic benefit of lymphadenectomy in advanced stage urothelial carcinoma of the upper urinary tract, but there is still a lack of prospective studies.
- Trial name
- NCT03474926
- Testing
- Routine Template-based lymphadenectomy, LND only for lymph nodes enlargement found in preoperative image or during surgery
- Where
- 2 sites in China
- Volunteers
- 504 people
- Sponsor
- RenJi Hospital
Peripheral Artery Disease, In-stent Restenosis
LDD in Treatment of Femoropopliteal ISR
This study will evaluate the effectiveness and safety of local drug delivery using TAPAS balloon catheter system in the treatment of femoropopliteal in-stent restenosis.
- Trial name
- NCT03521843
- Testing
- balloon dilation only, balloon dilation+local drug delivery
- Where
- China
- Volunteers
- 40 people
- Sponsor
- RenJi Hospital
Pulmonary Hypertension, Echocardiography
Cardiac Speckle Tracking Myocardial Strain Balance
The investigators intend to evaluate the function of left heart and right heart and the motion balance between four chambers of the heart by speckle tracking technique during the follow-up of patients with pulmonary hypertension…
- Trial name
- NCT03464591
- Where
- China
- Volunteers
- 30 people
- Sponsor
- RenJi Hospital
Rectal Cancer Stage III
Neoadjuvant Chemotherapy Combined With Cetuximab for EGFR Wild Type Locally Advanced Rectal Cancer
A number of pilot studies had shown high rate of complete resection after neoadjuvant chemotherapy alone for local advanced rectal cancer(LARC), but they did not increase the ratio of pathological complete response (pCR) which…
- Trial name
- NCT03391843
- Testing
- FOLFOXIRI+Cetuximab regimen
- Where
- China
- Volunteers
- 100 people
- Sponsor
- RenJi Hospital
Breast Cancer, Prostate Cancer
Stereotactic Body Radiation Therapy for Spinal Metastases in Favorite Tumors
Stereotactic Body Radiation Therapy(SBRT) for spinal metastases has been proved a good results in pain relieve and local control, However,the longterm of efficacy and safety of this regimen is unclear.The purpose of the study is…
- Conditions
- Breast Cancer, Prostate Cancer, Non Small Cell Lung Cancer
- Trial name
- NCT03392233
- Testing
- Stereotactic Body Radiation Therapy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- RenJi Hospital
Rectal Cancer
Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer
The concurrent neoadjuvant chemoradiation therapy is standard care for local advanced rectal cancer (LARC), however, this regimen may induce sorts of adverse events, and part of them even more severer.
- Trial name
- NCT02942563
- Testing
- FOLFOXIRI
- Where
- China
- Volunteers
- 100 people
- Sponsor
- RenJi Hospital
PCOS, Impaired Glucose Tolerance
Research of Intensive Metabolic Intervention Before Pregnancy in PCOS
To investigate whether intensive metabolic intervention of PCOS women before pregnancy can improve pregnancy outcome.Besides, the investigators aim to investigate the best therapy strategy of metabolic intervention before…
- Trial name
- PCOS (NCT03383068)
- Testing
- Acarbose 100 MG, Exenatide, Orlistat
- Where
- China
- Volunteers
- 160 people
- Sponsor
- RenJi Hospital
Peripheral Artery Disease, Endovascular Treatment
Study of DA+LDD in the Treatment of Femoropopliteal Occlusive Disease
This study will evaluate the effectiveness and safety of directional atherectomy plus local drug delivery using balloon catheter system in the treatment of femoropopliteal occlusive disease.
- Trial name
- NCT03380650
- Testing
- directional atherectomy and locol drug delivery, drug-coated balloon dilation
- Volunteers
- 40 people
- Sponsor
- RenJi Hospital