Clinical trials: sponsored by RenJi Hospital
Epithelial Ovarian Cancer
Plasma ctDNA Detection in Diagnosis of Epithelial Ovarian Cancer.
Epithelial ovarian cancer constitutes one of the most common gynecological malignancies.Because the ovaries lie in the deep pelvic cavity,most ovarian cancer patients are asymptomatic, rendering the majority often diagnosed at an…
- Trial name
- ctDNA_EOC (NCT03155451)
- Testing
- methylation markers screening
- Where
- China
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Breast Cancer
Effects of Dexmedetomidine on Breast Cancer Cell Function in Vitro
Dexmedetomidine is widely used as an anaesthetic for general anesthesia during surgery. Previous studies in cells and animals show that dexmedetomidine may promote cancer growth.
- Trial name
- NCT03108937
- Testing
- Dexmedetomidine, saline
- Where
- China
- Volunteers
- 24 people
- Sponsor
- RenJi Hospital
Systemic Lupus Erythematosus, Critical Illness
Accuracy, Feasibility and Acceptance of CGM Lupus
This is a prospective monocenter, non-randomised, open-lable single-group intervention diagnostic trial on the accuracy, reliability and feasibility of the continuous glucose monitoring system in critically systemic lupus…
- Conditions
- Systemic Lupus Erythematosus, Critical Illness, Diabetic Blood Glucose Monitoring
- Trial name
- NCT03296995
- Testing
- Flash glucose monitoring system
- Where
- China
- Volunteers
- 30 people
- Sponsor
- RenJi Hospital
Intracranial Pressure, Neurosurgery
Parameters Analysis in Neurosurgical Critical Patients Through Big Data Acquisition
The PANDA trial is a multicenter prospective observational study designed to analyze various ICP derived parameters and clinical status in neurosurgical critical patients through a new big data acquisition system.
- Conditions
- Intracranial Pressure, Neurosurgery, Information Management
- Trial name
- PANDA (NCT03087981)
- Where
- China
- Volunteers
- 120 people
- Sponsor
- RenJi Hospital
Acute ST-segment Elevation Myocardial Infarction
EARLY Routine Catheterization After Alteplase Fibrinolysis vs. PPCI in ST-Segment-Elevation MYOcardial Infarction
The EARLY-MYO (EARLY routine catheterization after alteplase fibrinolysis vs. primary PCI in acute ST-segment elevation MYOcardial infarction) is an investigator-initiated, prospective, multicenter, randomized (1:1), open-label…
- Trial name
- EARLY-MYO (NCT01930682)
- Testing
- Alteplase, Early post-fibrinolytic catheterisation, Primary PCI
- Where
- China
- Volunteers
- 344 people
- Sponsor
- RenJi Hospital
ST Segment Elevation Myocardial Infarction
Efficacy of Intracoronary Infusion of Different Medicine in STEMI Patients Undergoing Primary PCI
The study intends to evaluate the efficacy of different medicine delivering by targed perfusion catheter incoronary administration on epicardial, myocardial perfusion and clinical outcomes in STEMI patients undergoing primary PCI.
- Trial name
- NCT03252665
- Testing
- Alprostadil, Nicorandil, Nitroglycerin
- Where
- China
- Volunteers
- 600 people
- Sponsor
- RenJi Hospital
Ischemic Stroke
Ginkgo Diterpene Lactone Meglumine Injection on Platelet Reactivity in Acute Ischemic Stroke
This study evaluates the addition of Ginkgo Diterpene Lactone Meglumine Injection to aspirin in the treatment of acute ischemic stroke.Half of patient will receive Ginkgo Diterpene Lactone Meglumine Injection(25mg once/day…
- Trial name
- GDPRS (NCT03219645)
- Testing
- Ginkgo Diterpene Lactone Meglumine Injection, Acetylsalicylic acid
- Volunteers
- 40 people
- Sponsor
- RenJi Hospital
Anticoagulation, Minimally Invasive
Minimally Invasive Lumbar Aneasthesia Used for Cesarean Section
Spinal canal anesthesia is marked the most commonly used method of cesarean section. Traditional spinal anesthesia may cause post-dural puncture headache and low back pain.Plenty of parturients are undergoing anticoagulation…
- Conditions
- Anticoagulation, Minimally Invasive, Spinal Anesthesia
- Trial name
- NCT02987192
- Testing
- pen type 27 gauge needles, cutting type 22 gauge needles
- Where
- China
- Volunteers
- 200 people
- Sponsor
- RenJi Hospital
Lung; Disease, Interstitial, With Fibrosis, Dermatomyositis
Basiliximab Treating Interstitial Pneumonia of CADM
This is a 52-week, randomized, open and routine treatment controlled study. This study will assess the safety and efficacy of basiliximab as an add-on treatment for interstitial pneumonia in clinical amyopathic dermatomyositis…
- Trial name
- NCT03192657
- Testing
- Basiliximab, Calcineurin Inhibitors, Steroids
- Where
- China
- Volunteers
- 100 people
- Sponsor
- RenJi Hospital
Renal Cell Carcinoma
Comparison of Microwave Ablation-Assisted Enucleation and Conventional Laparoscopic Partial Nephrectomy in the Treatment of T1a Renal Cell Carcinoma
The purpose of this study is to evaluate the feasibility, safety and efficiency of zero ischemia laparoscopic microwave ablation-assisted enucleation in comparison with conventional laparoscopic partial nephrectomy in the…
- Trial name
- NCT02326558
- Testing
- laparoscopic microwave ablation-assisted enucleation, conventional laparoscopic partial nephrectomy
- Where
- China
- Volunteers
- 183 people
- Sponsor
- RenJi Hospital
Nonsmall Cell Lung Cancer
Effects of Acupuncture Stimulation on Systemic Inflammation
60 ASA physical status I or II patients, aged 18-75 years old , scheduled for elective video-assisted thoracoscopic lobectomy surgery,will be randomized into 2 groups,with 30 patients in each group: 1. control group and 2.
- Trial name
- NCT02951611
- Testing
- Acupuncture stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- RenJi Hospital
Neoplasms, Gastrointestinal
The Role of ctDNA, PVT1 and ROS in Diagnosis and Treatment of Gastrointestinal and Hepatobiliary Pancreatic Cancer
This study aims to evaluate the role of ct-DNA, PVT1 and reactive oxygen species (ROS) as biomarkers in the diagnosis, treatment and recurrence monitoring of gastrointestinal and hepatobiliary pancreatic cancer.
- Trial name
- NCT03076502
- Volunteers
- 500 people
- Sponsor
- RenJi Hospital
Brain Injuries, Traumatic, Body Temperature Changes
Postoperative Temperature Monitoring In Brain Trauma
This prospective observational study is designed to investigate the relationship between brain temperature, axillary temperature, rectal temperature, and bladder temperature of postoperative patients with brain trauma, and the…
- Trial name
- PTMIBT (NCT03068143)
- Where
- China
- Volunteers
- 150 people
- Sponsor
- RenJi Hospital
Kidney Diseases,Cystic
Efficacy and Safety of Microwave Ablation in BosniakⅠ~ⅡF Cystic Renal Lesions
The purpose of this study is to determine whether microwave ablation is more effective in the treatment of simple renal cysts than conventional laparoscopic decortication.
- Trial name
- NCT03068195
- Testing
- microwave ablation, laparoscopic decortication
- Where
- China
- Volunteers
- 300 people
- Sponsor
- RenJi Hospital
Systemic Sclerosis
Pirfenidone as Treatment of Skin Fibrosis in Systemic Sclerosis
This study is to evaluate the efficacy and safety of an antifibrotic agent, pirfenidone as treatment of systemic sclerosis. The primary outcome of this study is improvement of skin fibrosis.
- Trial name
- NCT03068234
- Testing
- Pirfenidone, Steroids
- Where
- China
- Volunteers
- 72 people
- Sponsor
- RenJi Hospital
Lupus Nephritis
Iguratimod as Treatment for Refractory Lupus Nephritis
This study is to evaluate the efficacy and safety of a novel chemical synthetic agent iguratimod as treatment of refractory lupus nephritis.
- Trial name
- NCT03054545
- Testing
- Iguratimod
- Where
- China
- Volunteers
- 30 people
- Sponsor
- RenJi Hospital
Tubular Breast Cancer, Mucinous Breast Cancer
Addition of Cisplatin to Neoadjuvant Therapy for T Locally Advanced Breast Cancer
The investigators hypotheses that paclitaxel combined with cisplatin in a weekly-based regimen as neoadjuvant chemotherapy is effective and tolerable for locally advanced breast cancer.
- Conditions
- Tubular Breast Cancer, Mucinous Breast Cancer, Invasive Ductal Breast Cancer, Inflammatory Breast Cancer
- Trial name
- SHPD001 (NCT02199418)
- Testing
- Paclitaxel, Cisplatin
- Where
- 2 sites in China
- Volunteers
- 132 people
- Sponsor
- RenJi Hospital
Chronic Pain, Mammary Cancer
Accurate Diagnosis System for Postoperative Chronic Pain Based on fMRI
Postoperative pain is an ideal model for study on acute pain changing into chronic pain. The functional imaging of magnetic resonance can reflect the extent and character of pain exactly and the structural imaging of it can be a…
- Trial name
- NCT03022864
- Volunteers
- 100 people
- Sponsor
- RenJi Hospital
Mean Arterial Pressure, Heart Rate
The Effects of Two Induction Means on Emergence After General Anesthesia
This study aims to investigate the effects of different methods of administration on emergence period after laryngeal mask anesthesia in elderly patients undergoing transurethral endoscopic operation
- Trial name
- NCT02974712
- Testing
- Fentanyl, Saline
- Volunteers
- 60 people
- Sponsor
- RenJi Hospital
Intracranial Aneurysm, Unruptured Cerebral Aneurysm
Chinese Small Intracranial Aneurysm Study (CSIAS)
Intracranial aneurysms are common in the general population. The overall prevalence of unruptured intracranial aneurysms (UIAs) is estimated of 2.3-3.2% in the population without specific risk factors for SAH.
- Conditions
- Intracranial Aneurysm, Unruptured Cerebral Aneurysm, Treatment Side Effects
- Trial name
- NCT02948504
- Testing
- Coiling or Clipping
- Volunteers
- 500 people
- Sponsor
- RenJi Hospital