Clinical trials: sponsored by Rennes University Hospital
SARS-CoV-2 Coronavirus, Acute Respiratory Distress Syndrome
Human Ab Response & immunoMONItoring of COVID-19 Patients
Prospective, mono centric study on COVID-19 patients with or without acute respiratory distress syndrome (ARDS) to analyse the dynamics of the immune response and to search for biomarkers of evolution
- Trial name
- HARMONICOV (NCT04373200)
- Testing
- Blood samples collection, Saliva collection
- Where
- France
- Volunteers
- 71 people
- Sponsor
- Rennes University Hospital
Premature Birth
Influence of Physical Treatments of Human Milk on the Kinetics of Gastric Lipolysis in Preterm Newborns
The optimization of newborns nutrition is a challenge especially for preterm newborns for whom nutrition plays a crucial part in cerebral and global development. Human milk is considered as the best food for newborns.
- Trial name
- ARCHILACT (NCT02112331)
- Testing
- Raw human milk, Pasteurized human milk, Pasteurized-homogenized human milk
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Rennes University Hospital
Stroke
General Anesthesia Versus Sedation During Intra-arterial Treatment for Stroke
In France, the annual incidence rate of acute ischaemic stroke is around 150 000 patients, 65 % of whom keep long-term disability.
- Trial name
- GASS (NCT02822144)
- Testing
- Etomidate, Succinylcholine, Propofol
- Where
- 4 sites in France
- Volunteers
- 351 people
- Sponsor
- Rennes University Hospital
Alzheimer or Mild Cognitive Impairment
ARIADE : Augmented Reality for Improving Autonomy in Dementia
Navigating according to a specific goal is a common activity of everyday life. Spatial navigation requires the implementation of motor and perceptual functions (sight, walking, proprioception), but also various cognitive…
- Trial name
- ARIADE (NCT04742465)
- Testing
- Augmented reality technological assistance for the movements of people with Alzheimer's disease or MCI in a controlled environment.
- Where
- France
- Volunteers
- 19 people
- Sponsor
- Rennes University Hospital
Chronic Obstructive Pulmonary Disease
Detection of COPD in Primary Care
Chronic obstructive pulmonary disease (COPD) is a common chronic disease with a significant medical and economic impact. Its prevalence is increasing and is estimated at 7.5% of people over 40 in France.
- Trial name
- DISCO (NCT03046199)
- Testing
- Questionnaire, Coordination
- Where
- France
- Volunteers
- 3,162 people
- Sponsor
- Rennes University Hospital
Transfusion
Place of Jugular Ultrasound in the Evaluation of the Volemia by a Clinician Doctor in Routine Care
Interventional study with minimal risks and constraints, prospective, monocentric.
- Trial name
- JUVIA (NCT03484052)
- Testing
- Jugular ultrasound
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Rennes University Hospital
Female Infertility
AROPE : Early Ovarian Reserve Decreased : Impact of Exposure to Persistent Endocrine Disruptors and Organic Solvents
Early ovarian reserve decreased is one of the main causes of infertility for women after 35 years. The relationship between this decreased and exposure to chemicals, including persistent endocrine disruptors or organic solvents…
- Trial name
- AROPE (NCT02802397)
- Testing
- Self-administered questionnaire and blood and urine samples
- Where
- 5 sites in France
- Volunteers
- 335 people
- Sponsor
- Rennes University Hospital
Alcoholism, Liver Disease
Transient Elastography in the Determination of Advanced Fibrosis in Alcoholic Liver Disease.
Alcoholic liver disease is the most frequent complication of excessive alcohol consumption. Early diagnosis of alcoholic liver disease is essential to avoid its complications that could be fatal.
- Conditions
- Alcoholism, Liver Disease, Liver Fibrosis
- Trial name
- FIBR-OH (NCT01789008)
- Testing
- Determination of Advanced Fibrosis in Alcoholic Liver Disease
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Rennes University Hospital
Sarcoidosis, Pulmonary
SARCOLOWDOSE : Ultra-low Dose CT Scan and MRI in Thoracic Sarcoidosis
The goal of this study is to evaluate the diagnostic agreement between, on the one hand, ultra-low dose CT and MRI with UTE pulse sequences, and on the other hand, standard CT scan, to quantify lung parenchyma patterns in…
- Trial name
- SARCOLOWDOSE (NCT03140644)
- Testing
- Patients with thoracic sarcoidosis
- Where
- 7 sites in France
- Volunteers
- 196 people
- Sponsor
- Rennes University Hospital
Heart; Surgery, Heart, Functional Disturbance as Result
Pre-operative Carriage of Respiratory VIRUSes, and Acute Respiratory Distress Syndrome After Heart Surgery
The main objective of our study is to determine whether asymptomatic influenza virus carriage is associated with an increased risk of post-operative Acute Respiratory Distress Syndrome (ARDS) after cardiac surgery.
- Trial name
- VIRUS-ATTAC (NCT04562207)
- Testing
- Screening for respiratory virus infection
- Where
- 5 sites in France
- Volunteers
- 1,256 people
- Sponsor
- Rennes University Hospital
Defibrillators, Implantable, Telemedicine
Evaluation of the " Tele-follow-up " for the Follow-up of Implantable Defibrillators
The implantable cardioverter defibrillator (ICD) has been shown to be effective in preventing mortality in patients with ventricular tachyarrhythmia.
- Trial name
- EVATEL (NCT00598026)
- Testing
- Tele- follow-up, Conventional follow-up
- Where
- 30 sites in France
- Volunteers
- 1,501 people
- Sponsor
- Rennes University Hospital
Parkinson's Disease
Cognitive Control in Parkinson's Disease
Cognitive action control allows resisting to irrelevant information to easily produce desired goal-directed behaviors. This cognitive process is disturbed in patients with Parkinson's disease (PD).
- Trial name
- EEGControl (NCT03981913)
- Testing
- Simon Task with high-density EEG recording
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Genetics, Diagnostic Techniques and Procedures
Genetics Tests : How to Improve Management Within Two Medical Specialities
This survey will assess discrepancies between official clinical genetics guidelines and practices within 3 West regions of France.
- Trial name
- ORGAGENE (NCT03572322)
- Testing
- Focus Group, Interviews
- Where
- France
- Volunteers
- 36 people
- Sponsor
- Rennes University Hospital
Heart Failure at NYHA Stage III or IV, Non Responders to Resynchronization
LVAD in Non Cardiac Transplant Candidates and Non Responders to Resynchronization
The prognosis for heart failure patients is bleak for the advanced stages of the disease, with a reported 6-month mortality rate of almost 50% in patients treated with chronic inotropic therapy.
- Conditions
- Heart Failure at NYHA Stage III or IV, Non Responders to Resynchronization, Non Candidates for Transplantation
- Trial name
- CHECKMATE (NCT01126944)
- Testing
- heart mate II
- Where
- 4 sites in France, Germany
- Sponsor
- Rennes University Hospital
Direct Anterior Total Hip Arthroplasty
Direct Anterior Total Hip Arthroplasty (THA), in Versus Outpatients : A Prospective Monocentric Study in Rennes University Hospital.
The main objective is to show that cumulative length of stay over the first 45 post operative days (i.e. : primary length of stay and readmission) is significantly lower in the outpatients group than in the inpatients group
- Trial name
- AHVACA (NCT03667339)
- Testing
- Direct Anterior Total Hip Arthroplasty
- Where
- France
- Volunteers
- 1 people
- Sponsor
- Rennes University Hospital
Adolescent Dysmenorrhea
Adolescent Dysmenorrhea : Prevalence, Severity, Experience and Management in the Use of Medication in High School Girls in Ille-et-Vilaine
Dysmenorrhea or painful menstruation is a common symptom of menses. Dysmenorrhea is defined as a painful, cramping sensation in the lower abdomen or back associated with menstrual periods and is classified into primary and…
- Trial name
- DAPsvs (NCT04007471)
- Testing
- Anonymous survey
- Where
- France
- Volunteers
- 979 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Idiopathic Scoliosis
Evaluation of Pain Following Scoliosis Surgery.
The main objective of this study was to evaluate acute pain following scoliosis surgery in adolescent.
- Trial name
- RACHIDOL (NCT03686371)
- Testing
- posterior surgery for spinal arthrodesis
- Where
- France
- Volunteers
- 51 people
- Sponsor
- Rennes University Hospital
Therapeutic Plasma Exchange
TPE in Rennes Hospital
To assess the indications, tolerance and side effects of therapeutic plasma exchange (TPE) performed at a University Hospital over 8 years
- Trial name
- COMPLASMA (NCT03888417)
- Testing
- Therapeutic plasma exchange (TPE)
- Where
- France
- Volunteers
- 190 people
- Sponsor
- Rennes University Hospital
Peritonitis
Children Peritonitis Ecology at CHU de Rennes - (IIAPEDIA)
The main objectif is assess the germs (species + antibiograms) implicated in children intra-abdominal infections (community acquired or nosocomial ) at CHU de Rennes.
- Trial name
- IIAPEDIA (NCT03668197)
- Testing
- microbiological analysis
- Where
- France
- Volunteers
- 149 people
- Sponsor
- Rennes University Hospital
Mild Head Injury, Anticoagulant
Medico-economic Interest of the Protein S100b in Mild Head Trauma Under Anti-thrombotics
Head trauma is a common injury in emergency department. Investigation to search for complication is guided by the clinical examination and the case history, such as taking anti-thrombotics.
- Conditions
- Mild Head Injury, Anticoagulant, Antiplatelet
- Trial name
- ISTCAT (NCT04305821)
- Testing
- Dosage of S100β protein
- Where
- France
- Volunteers
- 260 people
- Sponsor
- Rennes University Hospital