Clinical trials: sponsored by Rennes University Hospital
Hepatocellular Injury
Interest of Oxygenated Hypothermic Perfusion (PHO) in Preservation of Hepatic Grafts From Expanded Criteria Donors
Interest of oxygenated hypothermic perfusion in preservation of hepatic grafts from expanded criteria donors.
- Trial name
- PERPHO (NCT03376074)
- Testing
- Hypothermic oxygenated perfusion (HOPE), Conventional cold storage
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Rennes University Hospital
Brain Neoplasms
Presurgical Language Mapping With fMRI: Comparison of BOLD and fASL Techniques
One of the aim of the neurosurgical treatment of brain tumor is to offer the maximal resection with the minimal neurological risk.
- Trial name
- MALTA (NCT01793714)
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Rennes University Hospital
Colorectal Cancer, Hepatic Metastases
Evaluation of 2 Resection Strategies of Synchronous Colorectal Cancer Metastases
The surgical strategy for the treatment of synchronous colorectal cancer liver metastases has not still been defined. The purpose of this study is to compare two treatment strategies in which liver resection is performed either…
- Trial name
- METASYNC (NCT00264979)
- Testing
- Simultaneous surgery, Sequential surgery
- Where
- 14 sites in France
- Volunteers
- 105 people
- Sponsor
- Rennes University Hospital
Inflammatory Bowel Diseases
Chronic Inflammatory Bowel Diseases (IBD) and School Absenteeism
Study of the causes and rate of school absenteeism in children and adolescents with Inflammatory Bowel Disease.
- Trial name
- MICI School (NCT03270267)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 108 people
- Sponsor
- Rennes University Hospital
Alcoholism
Impact of Marketing of Alcohol Products on Young People
Impact of marketing of alcohol products on young people
- Trial name
- IMAJ (NCT03818750)
- Testing
- MRI, Alcohol Use Disorders Identification Test
- Where
- France
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Digestive System Surgical Procedure, Pancreaticoduodenectomy
Impact of the Absence of Nasogastric Decompression After Pancreaticoduodenectomy
The use of nasogastric (NG) decompression after pancreaticoduodenectomy (PD) is a current practice. NG tube is associated with a high rate of morbidity including pulmonary morbidity, delayed gastric emptying and finally an…
- Trial name
- IPOD (NCT02594956)
- Testing
- no nasogastric tube, nasogastric tube
- Where
- France
- Volunteers
- 125 people
- Sponsor
- Rennes University Hospital
Non Syndromic Congenital Heart
Non Syndromic Congenital Heart Defect and Array-CGH in Prenatal Diagnosis
Comparative genomic hybridization (CGH)-based microarrays are now often used during pregnancy in case of fetal polymalformation in order to assess significant genomic alterations.
- Trial name
- CAPA (NCT02333097)
- Where
- 2 sites in France
- Volunteers
- 78 people
- Sponsor
- Rennes University Hospital
Liver Transplantation
Immunosuppressive Therapy Optimization: Development of a Population Pharmacokinetic-pharmacodynamic (PK-PD) Model in Liver Transplantation
Prospective, non-randomized, open Pharmacokinetic-Pharmacogenetic-Pharmacodynamic monocentric study. Donor and recipient CYP3A5 genotype and recipient ABCB1 will not be communicate to clinicians or patients during the study.
- Trial name
- OPTILTH (NCT02877628)
- Testing
- Pharmacokinetic-pharmacodynamic model in liver transplantation
- Where
- France
- Volunteers
- 110 people
- Sponsor
- Rennes University Hospital
Bacterial Infection
Contribution of Real Time Analyses of CARdio-RESpiratory Signals to the Diagnosis of Infection in PREterM Infants
Hospital-acquired infections are common complications in preterm infants. The diagnosis has to be fast and accurate. Indeed, the early identification of a suspected infection is very important, since the early administration of…
- Trial name
- CARESS_PREMI (NCT01611740)
- Testing
- Analysis of the heart rate and respiratory characteristics / Telemonitoring system prototype developed by INSERM U-642
- Where
- 3 sites in France
- Volunteers
- 525 people
- Sponsor
- Rennes University Hospital
Epilepsy
Effects of Transcranial Direct Current Stimulation (TDCS) in Drug-resistant Partial Epilepsy
Drug-resistant partial epilepsy has a heavy impact on quality of life and sometimes on life expectancy itself. Only a minority of patients may benefit from a curative epilepsy surgery.
- Trial name
- BRAINSTIM (NCT02465970)
- Testing
- STARSTIM
- Where
- France
- Volunteers
- 5 people
- Sponsor
- Rennes University Hospital
Bacterial Infection
Effect of Oral Preparation on Bacterial Colonization of the Pharyngeal Mucosa in Surgery of Head and Neck Cancer
Surgical site infections are an important health indicator for hospitals and a significant medico-economic issue. The aim of the study is to assess the impact of chlorhexidine mouthwash performed before surgery on the bacterial…
- Trial name
- ORAL-ISO (NCT02753387)
- Testing
- Chlorhexidine, NaCl 0.9 %
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Rennes University Hospital
In-hospital Falls
In-hospital Falls and Hemorrhagic Complications : a Descriptive Analysis in Rennes University Hospital
Anticoagulant and antiplatelet treatments have well defined indactions, with a clearly proved benefit, respectivly for prevention of arterial and venous emblism and for prevention of athermo-related arterial thrombosis.
- Trial name
- HEMO-CIH (NCT03687541)
- Where
- France
- Volunteers
- 157 people
- Sponsor
- Rennes University Hospital
Prostate Cancer, Prostate Adenocarcinoma
Surgery Combined With Intensity Modulated Radiation Therapy - Image-Guided Radiation Therapy (IMRT-IGRT) in Locally-advanced Prostate Cancers
Standard treatment of locally-advanced prostate cancers consists in the association of radiotherapy of prostate and seminal vesicles (SV) and androgen deprivation (AD) for 3 years.
- Trial name
- TARGET (NCT01148069)
- Testing
- Surgery combined with IMRT-IGRT
- Where
- 2 sites in France
- Volunteers
- 63 people
- Sponsor
- Rennes University Hospital
Athletes With Isolated Non-ischemic LGE With no Underlying "Labelled" Cardiomyopathy
Effect of Intense Sport Practice in Athletes With Non-ischemic Scar
The prognostic relevance of isolated non-ischemic LGE (i.e. with no underlying "labelled" cardiomyopathy) is unclear, and current guidelines to not state on the clearance of athlete with this type of findings as regards to…
- Trial name
- EISCAR (NCT03780231)
- Testing
- non-ischemic scar
- Where
- 6 sites in Australia, Belgium and 4 more
- Volunteers
- 200 people
- Sponsor
- Rennes University Hospital
Adult Asylum Seekers Who Have Applied for Asylum at the Regional Prefecture in Rennes
Health Care Access for Asylum Seekers in Brittany : Description, Associated Factors and Levers of Improvement
The main objective of this research is to study the logics and the associated factors with asylum seekers use of dedicated health structures.
- Trial name
- ACCEDAB (NCT03754374)
- Testing
- access to healthcare
- Where
- 2 sites in France
- Volunteers
- 1,500 people
- Sponsor
- Rennes University Hospital
Neonatal Disorder
Design of a Non-invasive Multi-modal Neonatal Monitoring System
This is a preliminary study whose objectives are to define the clinical use cases and the constraints of the implementation of a multi-sensor image-sound system.
- Trial name
- VARI-NEONAT (NCT03270410)
- Testing
- Data collection
- Where
- France
- Volunteers
- 35 people
- Sponsor
- Rennes University Hospital
Anesthesia, Epidural, Pregnancy
Study PIEB vs PIEB: the Dose is it Variable According to the Patients
the main objective of this study is to compare the effectiveness of three groups of epidurals with three different programmed intermittent epidural bolus (PIEB)settings.
- Trial name
- DOPABIEB (NCT03690271)
- Where
- France
- Volunteers
- 170 people
- Sponsor
- Rennes University Hospital
Healthy
OSS-IRM: Optimization of MRI Sequences in Healthy Volunteers
Using MRI, many technical parameters can be changed to optimize the diagnostic quality of the examination. The study is interventionnal because healthy volunteers are not supposed to have an MRI exam.
- Trial name
- OSS-IRM (NCT03440983)
- Testing
- MRI data acquiring in healthy volunteers
- Where
- France
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
ExtraCorporeal Membrane Oxygenation
Costs of the Patient's Stay Under ExtraCorporeal Membrane Oxygenation From the Hospital Point of View: a Pilot Study at the Rennes University Hospital Center
The objective of this study is to determine the average cost of stay of a patient supported by ExtraCorporeal Membrane Oxygenation from the point of view of the hospital facility, during the hospitalization in which the ECMO was…
- Trial name
- ECMONOMY (NCT03686540)
- Testing
- ExtraCorporeal Membrane Oxygenation (ECMO)
- Where
- France
- Volunteers
- 620 people
- Sponsor
- Rennes University Hospital
Renal Angioplasty on Atherosclerotic Stenosis
Evaluation of Renal Angioplasty on Atherosclerotic Stenosis Since 2010
The interest of renal angioplasty in the nosological framework of atherosclerotic stenosis has been significantly challenged by STAR and ASTRAL clinical trials in 2009, confirmed by the CORAL study in 2014.
- Trial name
- PARAS (NCT03686358)
- Testing
- Renal artery angioplasty
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Rennes University Hospital